| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Dadmarz, J C Cawle. Heterogeneity of CLL: high CD23 antigen and alpha IFN receptor expression are features of favourable disease and of cell activation. British journal of haematology. vol 68. issue 3. 1988-05-18. PMID:2965599. |
there was no correlation between cd 19, 20, 22 and 24 antigen expression and either alpha ifnr numbers or clinical stage. |
1988-05-18 |
2023-08-11 |
Not clear |
| L A Compton, C K Mathews, W C Johnso. The conformation of T4 bacteriophage dihydrofolate reductase from circular dichroism. The Journal of biological chemistry. vol 262. issue 27. 1987-11-02. PMID:3308867. |
the characteristic peaks of the cd spectrum indicate that the enzyme has a lot of antiparallel beta-sheet, which is typical of the alpha + beta tertiary class of globular proteins. |
1987-11-02 |
2023-08-11 |
Not clear |
| T Lah, M Vihar, A Dubin, V Tur. Horse alpha 2-macroglobulin. Circular dichroism studies of conformational changes upon reaction with proteinases and methylamine. Biological chemistry Hoppe-Seyler. vol 368. issue 5. 1987-10-22. PMID:2441724. |
the cd spectra of horse alpha 2-macroglobulin resemble those of bovine und human alpha 2-macroglobulin. |
1987-10-22 |
2023-08-11 |
human |
| T Lah, M Vihar, A Dubin, V Tur. Horse alpha 2-macroglobulin. Circular dichroism studies of conformational changes upon reaction with proteinases and methylamine. Biological chemistry Hoppe-Seyler. vol 368. issue 5. 1987-10-22. PMID:2441724. |
the cd spectra were changed in a different manner after the interaction of alpha 2-macroglobulin with methylamine, trypsin and inactive or active cathepsin d, indicating that more than one conformational change occurs. |
1987-10-22 |
2023-08-11 |
human |
| M Otagiri, T Maruyama, T Imai, A Suenaga, Y Imamur. A comparative study of the interaction of warfarin with human alpha 1-acid glycoprotein and human albumin. The Journal of pharmacy and pharmacology. vol 39. issue 6. 1987-09-03. PMID:2886597. |
the difference in cd spectra observed for alpha 1-agp and ha indicated that the drug-binding sites of the two proteins might have different asymmetries. |
1987-09-03 |
2023-08-11 |
human |
| P Füglistaller, M Mimuro, F Suter, H Zube. Allophycocyanin complexes of the phycobilisome from Mastigocladus laminosus. Influence of the linker polypeptide L8.9C on the spectral properties of the phycobiliprotein subunits. Biological chemistry Hoppe-Seyler. vol 368. issue 4. 1987-08-28. PMID:3111493. |
the absorption and cd spectra of the complexes (alpha ap beta ap)3, (alpha ap beta ap)3l8.9c and (alpha apb alpha ap2 beta ap3)l8.9c could be deconvoluted into the spectra of the phycobiliprotein subunits. |
1987-08-28 |
2023-08-11 |
Not clear |
| K Mawatari, S Matsukawa, Y Yoneyam. Valency hybrid hemoglobins with special attention to subunit organization. Biomedica biochimica acta. vol 46. issue 2-3. 1987-06-26. PMID:3593313. |
to examine the effects of ferric spin state on the allosteric properties and the structure at the alpha 1 beta 2 subunit interface, we measured circular dichroism (cd) and deoxy minus oxy difference spectra in the ultraviolet (uv) region as well as the oxygen equilibrium curves for various ferric ligand complexes of valency hybrid hemoglobins (alpha +2 beta 2 and alpha 2 beta +2 : + signifies ferric heme). |
1987-06-26 |
2023-08-11 |
Not clear |
| K Mawatari, S Matsukawa, Y Yoneyam. Valency hybrid hemoglobins with special attention to subunit organization. Biomedica biochimica acta. vol 46. issue 2-3. 1987-06-26. PMID:3593313. |
the cd and difference spectral data strongly suggested that in both type of hybrids the alpha 1 beta 2 boundary structure of the high spin derivatives is different from that of the low spin ones. |
1987-06-26 |
2023-08-11 |
Not clear |
| M J Stillman, W Cai, A J Zelazowsk. Cadmium binding to metallothioneins. Domain specificity in reactions of alpha and beta fragments, apometallothionein, and zinc metallothionein with Cd2+. The Journal of biological chemistry. vol 262. issue 10. 1987-05-15. PMID:3558354. |
comparison between the band centers of the cd-alpha mt and cd-beta mt indicates that the cd spectrum of cd7-mt is dominated by intensity from transitions that originate on cd-s chromophores in the alpha domain, with little direct contribution from the beta domain. |
1987-05-15 |
2023-08-11 |
rat |
| M J Stillman, W Cai, A J Zelazowsk. Cadmium binding to metallothioneins. Domain specificity in reactions of alpha and beta fragments, apometallothionein, and zinc metallothionein with Cd2+. The Journal of biological chemistry. vol 262. issue 10. 1987-05-15. PMID:3558354. |
analysis of the spectra recorded during titrations of zn7-mt 2 with cd2+ suggests: (i) that cd2+ replaces zn2+ in zn7-mt isomorphously; (ii) that cadmium binds in a nonspecific, "distributed" manner across both domains; (iii) that cluster formation in the alpha domain only occurs after 4 mol eq of cadmium have been added and is indicated by the presence of a cluster-sensitive, cd spectral feature; (iv) that the characteristic derivative cd spectrum of native cd4,zn3-mt is only obtained from "synthetic" cd4,zn3-mt following a treatment cycle that allows the redistribution of cadmium into the alpha domain; warming the synthetic "native," cd4,zn3-mt, to 65 degrees c results in cadmium being preferentially bound in the alpha domain; and (v) zn7-mt will bind cd2+ quite normally at up to 65 degrees c but with greater specificity for the alpha domain compared with titrations carried out at 25 degrees c. these results suggest that the initial presence of zinc in both domains is an important factor in the lack of any domain specificity during cadmium binding to zn-mt which contrasts the domain specific manner observed for cadmium binding to apo-mt. |
1987-05-15 |
2023-08-11 |
rat |
| E Couture-Tosi, J Tapon-Bretaudière, F Pochon, M Barray, A Bros, E Delai. Ultrastructural and anti-proteinase activity modifications of human alpha 2-macroglobulin induced by zinc and other divalent cations. European journal of cell biology. vol 42. issue 2. 1987-03-30. PMID:2434330. |
native tetrameric alpha 2-macroglobulin molecules (alpha 2m) can be converted into a population of dimers by incubation with various divalent cations such as zn, cd, mg, cu, ni, co. |
1987-03-30 |
2023-08-11 |
human |
| G A Hitman, M J Niven, H Festenstein, P G Cassell, J Awad, J Walker-Smith, J N Leonard, L Fry, P Ciclitira, P Kuma. HLA class II alpha chain gene polymorphisms in patients with insulin-dependent diabetes mellitus, dermatitis herpetiformis, and celiac disease. The Journal of clinical investigation. vol 79. issue 2. 1987-03-12. PMID:3805283. |
we have investigated dna polymorphism of the class ii alpha chain genes in hla typed patients with insulin dependent diabetes mellitus (iddm; n = 79), celiac disease (cd; n = 46), dermatitis herpetiformis (dh; n = 53), and controls (n = 86). |
1987-03-12 |
2023-08-11 |
Not clear |
| G A Hitman, M J Niven, H Festenstein, P G Cassell, J Awad, J Walker-Smith, J N Leonard, L Fry, P Ciclitira, P Kuma. HLA class II alpha chain gene polymorphisms in patients with insulin-dependent diabetes mellitus, dermatitis herpetiformis, and celiac disease. The Journal of clinical investigation. vol 79. issue 2. 1987-03-12. PMID:3805283. |
in dr7 positive cd patients a 3.8-kilobase (kb) dr alpha fragment, which correlated with dqw3, was found in only 11% of patients compared with 45% of corresponding controls (p less than 0.05). |
1987-03-12 |
2023-08-11 |
Not clear |
| G A Hitman, M J Niven, H Festenstein, P G Cassell, J Awad, J Walker-Smith, J N Leonard, L Fry, P Ciclitira, P Kuma. HLA class II alpha chain gene polymorphisms in patients with insulin-dependent diabetes mellitus, dermatitis herpetiformis, and celiac disease. The Journal of clinical investigation. vol 79. issue 2. 1987-03-12. PMID:3805283. |
an increased frequency of a dx alpha genotype uu in all three diseases was found (iddm 59%, dh 45%, cd 48%, compared to 21% in controls, p less than 0.001), which is not explained solely by the increased frequencies of dr3-dx alpha u. |
1987-03-12 |
2023-08-11 |
Not clear |
| P Manavalan, D M Mittelstaedt, M I Schimerlik, W C Johnso. Conformational analysis of thymidylate synthase from amino acid sequence and circular dichroism. Biochemistry. vol 25. issue 21. 1987-02-11. PMID:3098289. |
further, the location of the predicted regions of alpha-helices and beta-strands along the sequence and the cd characteristics strongly suggest that this protein belongs to an alpha + beta structural class. |
1987-02-11 |
2023-08-11 |
Not clear |
| J Caburi-Martin, M C Garel, C Domenget, C Prehu, Y Beuzar. Contact inhibition within hemoglobin S polymer by thiol reagents. Biochimica et biophysica acta. vol 874. issue 1. 1986-12-10. PMID:3768379. |
crystallographic studies of molecular contacts within deoxyhbs crystals suggest that the cis inhibitory effect of n-ethylmaleimide can be explained by direct inhibition of 'external' contacts between double strands involving the cd corner of the alpha chains. |
1986-12-10 |
2023-08-11 |
Not clear |
| A Lewiński, M Pawlikowsk. Melatonin suppression of the colloid droplet formation in the thyroid is not related to the alteration of prostacyclin synthesis. Journal of pineal research. vol 3. issue 3. 1986-12-09. PMID:3772726. |
the goal of the present investigation has been to compare the effect of melatonin on the early secretory event in the thyroid follicular cells (thyroglobulin endocytosis; colloid droplet [cd] formation) and the effect of this pineal indoleamine on the release of a stable prostacyclin (pgi2) metabolite, 6-keto-pgf1 alpha from the thyroid. |
1986-12-09 |
2023-08-11 |
rat |
| C Tohyama, E Kobayashi, H Saito, N Sugihara, A Nakano, Y Mitan. Urinary alpha 1-microglobulin as an indicator protein of renal tubular dysfunction caused by environmental cadmium exposure. Journal of applied toxicology : JAT. vol 6. issue 3. 1986-08-04. PMID:2424964. |
the urinary and serum levels and the relative clearance of alpha 1-mg to creatinine clearance were compared with various parameters (age, urinary beta 2-microglobulin (beta 2-mg), total protein, cd, cu and zn, serum beta 2-mg, creatinine and blood urea nitrogen and relative clearances of alpha 1-mg, beta 2-mg, inorganic phosphate and uric acid). |
1986-08-04 |
2023-08-11 |
Not clear |
| C Tohyama, E Kobayashi, H Saito, N Sugihara, A Nakano, Y Mitan. Urinary alpha 1-microglobulin as an indicator protein of renal tubular dysfunction caused by environmental cadmium exposure. Journal of applied toxicology : JAT. vol 6. issue 3. 1986-08-04. PMID:2424964. |
it was found that the urinary excretion of alpha 1-mg is closely associated with the urinary cd and cu and with the indices of renal dysfunction listed above. |
1986-08-04 |
2023-08-11 |
Not clear |
| C Tohyama, E Kobayashi, H Saito, N Sugihara, A Nakano, Y Mitan. Urinary alpha 1-microglobulin as an indicator protein of renal tubular dysfunction caused by environmental cadmium exposure. Journal of applied toxicology : JAT. vol 6. issue 3. 1986-08-04. PMID:2424964. |
these results suggest that the urinary alpha 1-mg level markedly reflects a degree of proximal tubular dysfunction and that it may be useful as one of the screening measures for proximal tubular dysfunction caused by environmental cd exposure. |
1986-08-04 |
2023-08-11 |
Not clear |