| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M-Y Wan, Z-L Chen, J-W Gu, C-Y Ya. Amphipathic KALA fusogenic peptide enhances absorption of insulin and calcitonin by pulmonary membranes of rats. European review for medical and pharmacological sciences. vol 28. issue 15. 2024-08-28. PMID:39194196. |
amphipathic kala fusogenic peptide enhances absorption of insulin and calcitonin by pulmonary membranes of rats. |
2024-08-28 |
2024-08-30 |
rat |
| Elisa Moser, Ayako Ura, Loreen Vogel, Katja Steiger, Carolin Mogler, Matthias Evert, Bruno Märkl, Klemens Scheidhauer, Marc Martignoni, Helmut Friess, Alexander von Werder, Ilaria Marinoni, Aurel Perren, Günter Klöppel, Atsuko Kasajim. ARX, PDX1, ISL1 and CDX2 expression distinguishes five subgroups of PanNETs with correlations to histology, hormone expression and outcome. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2024-08-15. PMID:39147030. |
185 pannets (non-functioning 165, functioning 20) resected between 1996 and 2023 were classified into five subgroups (a1, a2, b, c, d) by cluster analysis based on arx, pdx1, isl1 and cdx2 expression and correlated with trabecular vs. solid histology, expression of insulin, glucagon, pp, somatostatin, serotonin, gastrin, calcitonin, acth, daxx/atrx, men1 and alt status by fish, and disease-free survival (dfs). |
2024-08-15 |
2024-08-18 |
Not clear |
| A T Larsen, K E Mohamed, E A Petersen, M A Karsdal, K Henrikse. The Insulin Sensitizer KBP-336 Prevents Diabetes-Induced Cognitive decline in ZDF Rats. The journal of prevention of Alzheimer's disease. vol 11. issue 4. 2024-07-24. PMID:39044524. |
dual amylin and calcitonin receptor agonists (dacras) elicit beneficial effects on glycemic control and insulin sensitivity. |
2024-07-24 |
2024-07-26 |
rat |
| Anna Thorsø Larsen, Khaled Elhady Mohamed, Simone Anna Melander, Morten Asser Karsdal, Kim Henrikse. The enduring metabolic improvement of combining dual amylin and calcitonin receptor agonist and semaglutide treatments in a rat model of obesity and diabetes. American journal of physiology. Endocrinology and metabolism. 2024-06-12. PMID:38864815. |
long-acting dual amylin and calcitonin receptor agonists (dacras) are novel candidates for the treatment of type 2 diabetes and obesity due to their beneficial effects on body weight, glucose control, and insulin action. |
2024-06-12 |
2024-06-14 |
rat |
| Nanna Wichmann Larsen, Serhii Kostrikov, Morten Borre Hansen, Claudia Ulrich Hjørringgaard, Niels Bent Larsen, Thomas Lars Andresen, Kasper Kristense. Interactions of oral permeation enhancers with lipid membranes in simulated intestinal environments. International journal of pharmaceutics. 2024-03-02. PMID:38430950. |
to mimic the molecular composition of the real intestinal environment, the experiments are performed with the two peptide drugs salmon calcitonin and desb30 insulin in fasted-state simulated intestinal fluid. |
2024-03-02 |
2024-03-06 |
Not clear |
| Simone Anna Melander, Anna Thorsø Larsen, Morten Asser Karsdal, Kim Henrikse. Are insulin sensitizers the new strategy to treat Type 1 diabetes? A long-acting dual amylin and calcitonin receptor agonist improves insulin-mediated glycaemic control and controls body weight. British journal of pharmacology. 2024-02-20. PMID:38378168. |
dual amylin and calcitonin receptor agonists are potent insulin sensitizers developed for type 2 diabetes (t2d) as they improve glucose control, reduce body weight, and attenuate hyperglucagonemia. |
2024-02-20 |
2024-02-23 |
Not clear |
| Dan Luo, Xiaoqing Ni, Hao Yang, Lu Feng, Zhaoqun Chen, Lan Ba. A Comprehensive Review of Advanced Nasal Delivery: Specially Insulin and Calcitonin. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2023-11-10. PMID:37949195. |
a comprehensive review of advanced nasal delivery: specially insulin and calcitonin. |
2023-11-10 |
2023-11-20 |
human |
| Dan Luo, Xiaoqing Ni, Hao Yang, Lu Feng, Zhaoqun Chen, Lan Ba. A Comprehensive Review of Advanced Nasal Delivery: Specially Insulin and Calcitonin. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2023-11-10. PMID:37949195. |
peptide drugs through nasal mucous membrane, such as insulin and calcitonin have been widely used in the medical field. |
2023-11-10 |
2023-11-20 |
human |
| Dan Luo, Xiaoqing Ni, Hao Yang, Lu Feng, Zhaoqun Chen, Lan Ba. A Comprehensive Review of Advanced Nasal Delivery: Specially Insulin and Calcitonin. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2023-11-10. PMID:37949195. |
the most studies were insulin and calcitonin. |
2023-11-10 |
2023-11-20 |
human |
| Tomoko Kaketaka, Ikuo Mineo, Yu Kimura, Naohiko Ito, Yukiyoshi Okauchi, Hiromi Tamura, Shiro Adachi, Hiromi Iwahash. A Case of Insulinoma with Hyperprocalcitoninemia and Hypercalcitoninemia Showing Coexpression of Insulin and Calcitonin in Its Tumor Cells. Internal medicine (Tokyo, Japan). 2023-10-15. PMID:37839887. |
a case of insulinoma with hyperprocalcitoninemia and hypercalcitoninemia showing coexpression of insulin and calcitonin in its tumor cells. |
2023-10-15 |
2023-11-08 |
Not clear |
| Tomoko Kaketaka, Ikuo Mineo, Yu Kimura, Naohiko Ito, Yukiyoshi Okauchi, Hiromi Tamura, Shiro Adachi, Hiromi Iwahash. A Case of Insulinoma with Hyperprocalcitoninemia and Hypercalcitoninemia Showing Coexpression of Insulin and Calcitonin in Its Tumor Cells. Internal medicine (Tokyo, Japan). 2023-10-15. PMID:37839887. |
immunohistochemical analyses confirmed the co-staining of calcitonin and insulin immunoreactivity in the tumor cells, suggesting a calcitonin-producing insulinoma. |
2023-10-15 |
2023-11-08 |
Not clear |
| Marcello Martinez Morales, Christopher F van der Walle, Jeremy P Derric. Modulation of the Fibrillation Kinetics and Morphology of a Therapeutic Peptide by Cucurbit[7]uril. Molecular pharmaceutics. 2023-06-16. PMID:37327060. |
cucurbit[7]urils (cb[7]), a group of water soluble macrocycles, have been reported to suppress fibrillation in insulin and human calcitonin through association with phe and tyr residues which drive fibril formation. |
2023-06-16 |
2023-08-14 |
human |
| Anna Thorsø Larsen, Simone A Melander, Nina Sonne, Emma Bredtoft, Mays Al-Rubai, Morten A Karsdal, Kim Henrikse. Dual amylin and calcitonin receptor agonist treatment improves insulin sensitivity and increases muscle-specific glucose uptake independent of weight loss. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 164. 2023-06-03. PMID:37269811. |
dual amylin and calcitonin receptor agonist treatment improves insulin sensitivity and increases muscle-specific glucose uptake independent of weight loss. |
2023-06-03 |
2023-08-14 |
rat |
| Anna Thorsø Larsen, Simone A Melander, Nina Sonne, Emma Bredtoft, Mays Al-Rubai, Morten A Karsdal, Kim Henrikse. Dual amylin and calcitonin receptor agonist treatment improves insulin sensitivity and increases muscle-specific glucose uptake independent of weight loss. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 164. 2023-06-03. PMID:37269811. |
dual amylin and calcitonin receptor agonists (dacras) are known to induce significant weight loss as well as improve glucose tolerance, glucose control, and insulin action in rats. |
2023-06-03 |
2023-08-14 |
rat |
| Lihua Wang, Xianghui Qin, Maojuan Y. The influence of interventional measures on metabolic factors in fluoride and aluminum combined poisoning bones. Biotechnology & genetic engineering reviews. 2023-05-02. PMID:37130242. |
serum samples were collected and radioimmunoassay (ria) was used to measure osteocalcin (bgp), calcitonin (ct), parathyroid hormone (pht) and insulin growth factor i (igf-1) levels after 90 and 165 days of intervention. |
2023-05-02 |
2023-08-14 |
rat |
| Zachary S Clauss, Rolande Meudom, Bo Su, Michael A VandenBerg, Simranpreet S Saini, Matthew J Webber, Danny Hung-Chieh Chou, Jessica R Krame. Supramolecular Protein Stabilization with Zwitterionic Polypeptide-Cucurbit[7]uril Conjugates. Biomacromolecules. 2022-12-13. PMID:36512327. |
in this work, we investigated zwitterionic polypeptides prepared using a rapid and scalable polymerization technique and conjugated to a supramolecular macrocycle host, cucurbit[7]uril, for the ability to inhibit aggregation of model protein therapeutics insulin and calcitonin. |
2022-12-13 |
2023-08-14 |
human |
| Zachary S Clauss, Rolande Meudom, Bo Su, Michael A VandenBerg, Simranpreet S Saini, Matthew J Webber, Danny Hung-Chieh Chou, Jessica R Krame. Supramolecular Protein Stabilization with Zwitterionic Polypeptide-Cucurbit[7]uril Conjugates. Biomacromolecules. 2022-12-13. PMID:36512327. |
only conjugates prepared from zwitterionic structures of sufficient chain lengths were efficient inhibitors of insulin aggregation and could also inhibit aggregation of calcitonin. |
2022-12-13 |
2023-08-14 |
human |
| Swapna Poudwal, Pravin Shend. Multi-strategic approaches for enhancing active transportation using self-emulsifying drug delivery system. Journal of drug targeting. 2022-04-22. PMID:35451898. |
oral delivery is the most desired route of drug administration and it can be more beneficial for patients suffering from chronic diseases wherein frequent parenteral administration of proteins such as insulin and calcitonin is required. |
2022-04-22 |
2023-08-13 |
Not clear |
| David S Mathiesen, Asger Lund, Jens J Holst, Filip K Knop, Thomas A Lutz, Jonatan I Bagge. Amylin and calcitonin - physiology and pharmacology. European journal of endocrinology. 2022-03-30. PMID:35353712. |
however, calcitonin, particularly of salmon origin, has also been shown to affect insulin sensitivity, reduce gastric emptying rate and promote satiation. |
2022-03-30 |
2023-08-13 |
Not clear |
| David S Mathiesen, Asger Lund, Jens J Holst, Filip K Knop, Thomas A Lutz, Jonatan I Bagge. Amylin and calcitonin - physiology and pharmacology. European journal of endocrinology. 2022-03-30. PMID:35353712. |
pre-clinical trials with agents targeting the calcitonin receptor and the amylin receptors, which are based on the calcitonin core receptor, show improvements in several parameters of glucose metabolism including insulin sensitivity and some of these agents are currently undergoing clinical trials. |
2022-03-30 |
2023-08-13 |
Not clear |