| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Amrita Benoy, Lik-Wei Wong, Niha Ather, Sreedharan Sajikuma. Serotonin facilitates late-associative plasticity via synaptic tagging/cross-tagging and capture at hippocampal CA2 synapses in male rats. Oxford open neuroscience. vol 1. 2024-04-10. PMID:38596711. |
here, we show that bath-application of serotonin facilitates the persistence of long-term depression (ltd) at the ca3 schaffer collateral inputs to ca2 neurons (sc-ca2) when coupled to a weak low frequency electrical stimulation, in acute rat hippocampal slices. |
2024-04-10 |
2024-04-12 |
rat |
| Qiao Ye, Gocylen Gast, Erik George Wilfley, Hanh Huynh, Chelsea Hays, Todd C Holmes, Xiangmin X. Monosynaptic rabies tracing reveals sex- and age-dependent dorsal subiculum connectivity alterations in an Alzheimer's disease mouse model. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-03-19. PMID:38503494. |
input-mapped brain regions include hippocampal subregions (ca1, ca2, ca3), medial septum and diagonal band (ms-db), retrosplenial cortex (rsc), sub, post subiculum (postsub), visual cortex (vis), auditory cortex (aud), somatosensory cortex (ss), entorhinal cortex (ec), thalamus, perirhinal cortex (prh), ectorhinal cortex (ect) and temporal association cortex (tea). |
2024-03-19 |
2024-03-23 |
mouse |
| Preston N Siegler, Emma K Shaughnessy, Brian Horman, Tia T Vierling, Darron H King, Heather B Patisaul, Kim L Huhman, Georgia M Alexander, Serena M Dude. Identification of hippocampal area CA2 in hamster and vole brain. The Journal of comparative neurology. vol 532. issue 3. 2024-03-18. PMID:38497661. |
identification of hippocampal area ca2 in hamster and vole brain. |
2024-03-18 |
2024-03-20 |
mouse |
| Preston N Siegler, Emma K Shaughnessy, Brian Horman, Tia T Vierling, Darron H King, Heather B Patisaul, Kim L Huhman, Georgia M Alexander, Serena M Dude. Identification of hippocampal area CA2 in hamster and vole brain. The Journal of comparative neurology. vol 532. issue 3. 2024-03-18. PMID:38497661. |
hippocampal area ca2 is known to play a key role in these behaviors in mice and responds to social stimuli in rats, but ca2 has yet to be characterized in hamsters or voles, which are also used in studies of social behaviors. |
2024-03-18 |
2024-03-20 |
mouse |
| Preston N Siegler, Emma K Shaughnessy, Brian Horman, Tia T Vierling, Darron H King, Heather B Patisaul, Kim L Huhman, Georgia M Alexander, Serena M Dude. Identification of hippocampal area CA2 in hamster and vole brain. The Journal of comparative neurology. vol 532. issue 3. 2024-03-18. PMID:38497661. |
however, pnn staining is not useful for identifying ca2 in voles or hamsters, suggestive of differing roles for either pnns or for the hippocampal subregions in social behavior. |
2024-03-18 |
2024-03-20 |
mouse |
| Qiaoyun Ren, Susu Wang, Junru Li, Kun Cao, Mei Zhuang, Miao Wu, Junhua Geng, Zhengping Jia, Wei Xie, An Li. Novel social stimulation ameliorates memory deficit in Alzheimer's disease model through activating α-secretase. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-02-28. PMID:38418221. |
in this study, we found that single novel social (sns) stimulation promoted c-fos expression, and increased the protein levels of mature adam10/17 and sappα in the ventral hippocampus (vhpc) of wild-type (wt) mice, which are hippocampal dorsal ca2 (dca2) neuron activity and vhpc nmdar dependent. |
2024-02-28 |
2024-03-02 |
mouse |
| Preston Nicole Siegler, Emma K Shaughnessy, Brian Horman, Tia T Vierling, Darron H King, Heather B Patisaul, Kim L Huhman, Georgia M Alexander, Serena M Dude. Identification of hippocampal area CA2 in hamster and vole brain. bioRxiv : the preprint server for biology. 2024-02-26. PMID:38405991. |
identification of hippocampal area ca2 in hamster and vole brain. |
2024-02-26 |
2024-02-28 |
Not clear |
| Izabelle Dias Benfato, Ana Carolina Silvares Quintanilha, Jessica Salles Henrique, Melyssa Alves Souza, Barbara Dos Anjos Rosário, Jose Ivo Araújo Beserra Filho, Alessandra Mussi Ribeiro, Luciana Le Sueur Maluf, Camila Aparecida Machado de Oliveir. Long-term calorie restriction prevented memory impairment in middle-aged male mice and increased a marker of dna oxidative stress in hippocampal dentate gyrus. Neurobiology of learning and memory. 2024-02-09. PMID:38336097. |
in addition, immunohistochemistry targetingΔfosb (neuronal activity),brain-derived neurotrophic factor (bdnf) and thedna oxidative damage (8ohdg) in hippocampal subfields ca1, ca2, ca3, and dentate gyrus (dg), and in basolateral amygdala and striatum were performed. |
2024-02-09 |
2024-02-12 |
mouse |
| Paola Palombo, Roberta Maeda, Caroline Riberti Zanibon, Sheila Antonagi Engi, Thais Yokoyama, Natalia Bonetti Bertagna, Agusto Anesio, Paula Cristina Bianchi, Thamires Riggi, Gabrielle Emily Boaventura Tavares, Fernando Bezerra Romualdo da Silva Caden Souccar, Fabio Cardoso Cr. Unlocking the role of dorsal hippocampal α4β2 nicotinic acetylcholine receptors in Ethanol-Induced conditioned place preference in mice. Neuroscience letters. 2024-02-08. PMID:38331019. |
our results unveiled that ethanol-induced cpp was associated with an increase fos -positive cells in various subregions of the dorsal hippocampus, including ca1, ca2, ca3, and the dentate gyrus. |
2024-02-08 |
2024-02-11 |
mouse |
| Robert H Oakley, Natallia V Riddick, Sheryl S Moy, John A Cidlowsk. Imbalanced glucocorticoid and mineralocorticoid stress hormone receptor function has sex-dependent and independent regulatory effects in the mouse hippocampus. Neurobiology of stress. vol 28. 2023-12-11. PMID:38075021. |
to elucidate the sex-specific and independent actions of glucocorticoids in the hippocampus, we developed knockout mice lacking hippocampal gr, mr, or both gr and mr. mice deficient in hippocampal mr or both gr and mr showed an altered molecular phenotype of ca2 neurons and reduced anxiety-like behavior in both sexes, but altered stress adaptation behavior only in females and enhanced fear-motivated cue learning only in males. |
2023-12-11 |
2023-12-17 |
mouse |
| Keerthi Thirtamara Rajamani, Marie Barbier, Arthur Lefevre, Kristi Niblo, Nicholas Cordero, Shai Netser, Valery Grinevich, Shlomo Wagner, Hala Harony-Nicola. Oxytocin activity in the paraventricular and supramammillary nuclei of the hypothalamus is essential for social recognition memory in rats. Molecular psychiatry. 2023-12-05. PMID:38052983. |
we used multiplex fluorescence in situ hybridization to label oxytocin receptors in the sum and determined that they are predominantly expressed in glutamatergic neurons, including those that project to the ca2 region of the hippocampus. |
2023-12-05 |
2023-12-10 |
rat |
| Etienne Aumont, Aurélie Bussy, Marc-André Bedard, Gleb Bezgin, Joseph Therriault, Melissa Savard, Jaime Fernandez Arias, Viviane Sziklas, Paolo Vitali, Nina Margherita Poltronetti, Vanessa Pallen, Emilie Thomas, Serge Gauthier, Eliane Kobayashi, Nesrine Rahmouni, Jenna Stevenson, Cecile Tissot, Mallar M Chakravarty, Pedro Rosa-Net. Hippocampal subfield associations with memory depend on stimulus modality and retrieval mode. Brain communications. vol 5. issue 6. 2023-11-30. PMID:38035364. |
we segmented the right and left hippocampi into (i) dentate gyrus and cornu ammonis 4 (dg/ca4); (ii) ca2 and ca3 (ca2/ca3); (iii) ca1; (iv) strata radiatum, lacunosum and moleculare; and (v) subiculum. |
2023-11-30 |
2023-12-10 |
human |
| Sophie Nader, Esma Karlovich, Etty P Cortes, Ricardo Insausti, Gregory Meloni, Michelle Jacobs, John F Crary, Susan Morgell. Predictors of hippocampal tauopathy in people with and at risk for human immunodeficiency virus infection. Journal of neurovirology. 2023-11-05. PMID:37926797. |
subfield p-tau predictors were for cornu ammonis (ca)1, age; for ca2 and subiculum, seizure history; for ca3, seizure history and head trauma; and for ca4/dentate, history of hepatitis c virus (hcv) infection. |
2023-11-05 |
2023-11-08 |
human |
| Yeon Hee Yu, Seong-Wook Kim, Hyuna Im, Yu Ran Lee, Gun Woo Kim, Seongho Ryu, Dae-Kyoon Park, Duk-Soo Ki. Febrile Seizure Causes Deficit in Social Novelty, Gliosis, and Proinflammatory Cytokine Response in the Hippocampal CA2 Region in Rats. Cells. vol 12. issue 20. 2023-10-27. PMID:37887290. |
febrile seizure causes deficit in social novelty, gliosis, and proinflammatory cytokine response in the hippocampal ca2 region in rats. |
2023-10-27 |
2023-11-08 |
rat |
| Yeon Hee Yu, Seong-Wook Kim, Hyuna Im, Yu Ran Lee, Gun Woo Kim, Seongho Ryu, Dae-Kyoon Park, Duk-Soo Ki. Febrile Seizure Causes Deficit in Social Novelty, Gliosis, and Proinflammatory Cytokine Response in the Hippocampal CA2 Region in Rats. Cells. vol 12. issue 20. 2023-10-27. PMID:37887290. |
in addition, fs model juvenile rats showed enhanced levels of gliosis and inflammation in the hippocampal ca2 region and cerebellum. |
2023-10-27 |
2023-11-08 |
rat |
| G P Ossani, M A Riudavets, V D'Annunzio, A M Uceda, O Ponzo, N R Lago, D J Martin. Effect of lithium in pyramidal neurons of Cornu Ammonis in an animal model. Journal of psychiatric research. vol 167. 2023-10-12. PMID:37826875. |
as a result of this histological analysis, cell body area and nuclear area were significantly larger in the experimental group in a specific area of the cornu ammonis that could correspond to ca2 or the transition between ca1 and ca2. |
2023-10-12 |
2023-10-15 |
rat |
| Yu-Tzu Shih, Jason Bondoc Alipio, Amar Saha. An inhibitory circuit-based enhancer of DYRK1A function reverses Dyrk1a-associated impairment in social recognition. Neuron. vol 111. issue 19. 2023-10-05. PMID:37797581. |
here, we identify a social experience-sensitive mechanism in hippocampal mossy fiber-parvalbumin interneuron (pv in) synapses by which dyrk1a recruits feedforward inhibition of ca3 and ca2 to promote social recognition. |
2023-10-05 |
2023-10-07 |
mouse |
| Su Hyun Lee, Nicholas I Cilz, Sarah K Williams Avram, Adi Cymerblit-Sabba, June Song, Karis Courey, Austin Howley, Michaela E Cooke, W Scott Youn. Stimulation of median raphe terminals in dorsal CA2 reduces social investigation in male mice specifically investigating social stimulus of ovariectomized female mice. bioRxiv : the preprint server for biology. 2023-09-11. PMID:37693526. |
the cornu ammonis area 2 (ca2) region is essential for social behaviors, especially in social aggression and social memory. |
2023-09-11 |
2023-10-07 |
mouse |
| Su Hyun Lee, Nicholas I Cilz, Sarah K Williams Avram, Adi Cymerblit-Sabba, June Song, Karis Courey, Austin Howley, Michaela E Cooke, W Scott Youn. Stimulation of median raphe terminals in dorsal CA2 reduces social investigation in male mice specifically investigating social stimulus of ovariectomized female mice. bioRxiv : the preprint server for biology. 2023-09-11. PMID:37693526. |
in addition, the ca2 area of the mouse hippocampus receives neuronal inputs from other regions including the septal nuclei, the diagonal bands of broca, supramammillary nuclei, and median raphe nucleus. |
2023-09-11 |
2023-10-07 |
mouse |
| Su Hyun Lee, Nicholas I Cilz, Sarah K Williams Avram, Adi Cymerblit-Sabba, June Song, Karis Courey, Austin Howley, Michaela E Cooke, W Scott Youn. Stimulation of median raphe terminals in dorsal CA2 reduces social investigation in male mice specifically investigating social stimulus of ovariectomized female mice. bioRxiv : the preprint server for biology. 2023-09-11. PMID:37693526. |
a functional role of median raphe (mr) - ca2 projection is supported by the mr to ca2 projections and 82% reduction of hippocampal serotonin (5-ht) levels following mr lesions. |
2023-09-11 |
2023-10-07 |
mouse |