Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Qiang Zhang, Ping Wu, Feixiang Chen, Yanan Zhao, Yinping Li, Xiaohua He, Céline Huselstein, Qifa Ye, Zan Tong, Yun Che. Brain Derived Neurotrophic Factor and Glial Cell Line-Derived Neurotrophic Factor-Transfected Bone Mesenchymal Stem Cells for the Repair of Periphery Nerve Injury. Frontiers in bioengineering and biotechnology. vol 8. 2020-09-28. PMID:32850732. |
in order to further improve their nerve repairing efficiency, the bone mesenchymal stem cells (bmscs) overexpressing brain derived neurotrophic factor (bdnf) and glial cell line-derived neurotrophic factor (gdnf) were introduced into the conduits as seed cells and then were used to repair the 10-mm sciatic nerve defects in rats. |
2020-09-28 |
2023-08-13 |
rat |
Tadashi Nakaji-Hirabayashi, Kurumi Fujimoto, Chiaki Yoshikawa, Hiromi Kitan. Functional surfaces for efficient differentiation of neural stem/progenitor cells into dopaminergic neurons. Journal of biomedical materials research. Part A. vol 107. issue 4. 2020-06-17. PMID:30597732. |
oligohistidine-fused brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor, synthesized using genetic engineering, were co-immobilized on the surface via metal chelation. |
2020-06-17 |
2023-08-13 |
Not clear |
Merve Çapkın Yurtsever, Arlin Kiremitci, Menemşe Gümüşderelioğl. Dopaminergic induction of human dental pulp stem cells by photobiomodulation: comparison of 660nm laser light and polychromatic light in the nir. Journal of photochemistry and photobiology. B, Biology. vol 204. 2020-03-11. PMID:31982670. |
real time rt-qpcr analysis indicated that expressions of brain derived neurotrophic factor (bdnf), glial cell line derived neurotropic factor (gndf), matrix associated protein 2 (map2), nuclear receptor related 1 protein (nurr1) and dopamine transporter (dat) were increased, especially in the first 7 days of dopaminergic induction when 660 nm laser light was applied with a total energy density of 1.6 j/cm |
2020-03-11 |
2023-08-13 |
human |
Mark D Underwood, Mihran J Bakalian, Teresa Escobar, Suham Kassir, J John Mann, Victoria Arang. Early-Life Adversity, but Not Suicide, Is Associated With Less Prefrontal Cortex Gray Matter in Adulthood. The international journal of neuropsychopharmacology. vol 22. issue 5. 2020-02-28. PMID:30911751. |
we previously found reduced neurotrophic factor brain-derived neurotrophic factor in suicide decedents and with early-life adversity, and we sought to determine whether cortex thickness or neuron or glia density in the dorsolateral prefrontal and anterior cingulate cortex are associated with early-life adversity or suicide. |
2020-02-28 |
2023-08-13 |
Not clear |
Hao-Yun Zhang, Ning Song, Hong Jiang, Ming-Xia Bi, Jun-Xia Xi. Brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor inhibit ferrous iron influx via divalent metal transporter 1 and iron regulatory protein 1 regulation in ventral mesencephalic neurons. Biochimica et biophysica acta. vol 1843. issue 12. 2019-11-20. PMID:25239763. |
brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor inhibit ferrous iron influx via divalent metal transporter 1 and iron regulatory protein 1 regulation in ventral mesencephalic neurons. |
2019-11-20 |
2023-08-13 |
Not clear |
Changxiang Li, Xueqian Wang, Fafeng Cheng, Xin Du, Juntang Yan, Changming Zhai, Jie Mu, Qingguo Wan. Geniposide protects against hypoxia/reperfusion-induced blood-brain barrier impairment by increasing tight junction protein expression and decreasing inflammation, oxidative stress, and apoptosis in an in vitro system. European journal of pharmacology. vol 854. 2019-11-11. PMID:30995438. |
notably, gen pretreatment effectively improved the bbb function by decreasing the permeability of the bbb, promoting expression of tight junction proteins (zonula occludens-1, claudin-5, and occludin) and gamma-glutamyl transpeptidase, increasing transendothelial electrical resistance, mitigating oxidative stress damage and the release of inflammatory cytokines, downregulating the expression levels of matrix metallopeptidases-9 (mmp-9) and mmp-2, and increasing the release of brain derived neurotrophic factor and glial cell derived neurotrophic factor. |
2019-11-11 |
2023-08-13 |
Not clear |
Rafieh Alizadeh, Seyed Kamran Kamrava, Zohreh Bagher, Mohammad Farhadi, Masoumeh Falah, Fatemeh Moradi, Mahdi Eskandarian Boroujeni, Maryam Soleimani, Ahmadreza Kamyab, Ali Komeil. Human olfactory stem cells: As a promising source of dopaminergic neuron-like cells for treatment of Parkinson's disease. Neuroscience letters. vol 696. 2019-09-02. PMID:30552942. |
oe-mscs were induced to differentiate to da neuron-like cells in vitro by using sonic hedgehog (shh), fibroblast growth factor 8 (fgf8), basic fibroblast growth factor (bfgf), glial cell line-derived neurotrophic factor (gdnf) and brain derived neurotrophic factor (bdnf). |
2019-09-02 |
2023-08-13 |
human |
Yun-Hong Cheon, Seung-Geun Lee, Mingyo Kim, Hyun-Ok Kim, Young Sun Suh, Ki-Soo Park, Rock Bum Kim, Hyun-Su Yang, Ji-Min Kim, Chang-Nam Son, Eun Kyoung Park, Sang-Hyon Kim, Sang-Il Le. The association of disease activity, pro-inflammatory cytokines, and neurotrophic factors with depression in patients with rheumatoid arthritis. Brain, behavior, and immunity. vol 73. 2019-08-06. PMID:29787856. |
inflammation and trophic factors (brain-derived neurotrophic factor [bdnf], vascular endothelial growth factor, glial cell line-derived neurotrophic factor, and insulin-like growth factor-1) are associated with depression in the general population. |
2019-08-06 |
2023-08-13 |
Not clear |
Fábio G Teixeira, Miguel M Carvalho, Krishna M Panchalingam, Ana J Rodrigues, Bárbara Mendes-Pinheiro, Sandra Anjo, Bruno Manadas, Leo A Behie, Nuno Sousa, António J Salgad. Impact of the Secretome of Human Mesenchymal Stem Cells on Brain Structure and Animal Behavior in a Rat Model of Parkinson's Disease. Stem cells translational medicine. vol 6. issue 2. 2019-07-08. PMID:28191785. |
finally, proteomic characterization of the msc secretome (through combined mass spectrometry analysis and bioplex assays) revealed the presence of important neuroregulatory molecules, namely cystatin c, glia-derived nexin, galectin-1, pigment epithelium-derived factor, vascular endothelial growth factor, brain-derived neurotrophic factor, interleukin-6, and glial cell line-derived neurotrophic factor. |
2019-07-08 |
2023-08-13 |
human |
Sheng-Jie Shiue, Ruey-Horng Rau, Han-Shiang Shiue, Yi-Wei Hung, Zhi-Xiang Li, Kuender D Yang, Jen-Kun Chen. Mesenchymal stem cell exosomes as a cell-free therapy for nerve injury-induced pain in rats. Pain. vol 160. issue 1. 2019-06-26. PMID:30188455. |
exosomes also inhibited the level of tnf-α and il-1β, while enhanced the level of il-10, brain-derived neurotrophic factor, and glial cell line-derived neurotrophic factor in the ipsilateral l5/6 dorsal root ganglion of nerve-ligated rats, indicating anti-inflammatory and proneurotrophic abilities. |
2019-06-26 |
2023-08-13 |
human |
Patrícia C R Rabelo, Nayara A C Horta, Letícia M S Cordeiro, Maristela O Poletini, Cândido C Coimbra, Raphael E Szawka, Danusa D Soare. Intrinsic exercise capacity in rats influences dopamine neuroplasticity induced by physical training. Journal of applied physiology (Bethesda, Md. : 1985). vol 123. issue 6. 2019-06-20. PMID:28883047. |
to evaluate the dopaminergic neuroplasticity, we analyzed mrna levels of d1 receptor, d2 receptor, dopamine transporter, tyrosine hydroxylase, glia cell line neurotrophic factor, and brain-derived neurotrophic factor as well as concentrations of dopamine, serotonin, and their metabolites. |
2019-06-20 |
2023-08-13 |
rat |
Franciane Bobinski, Juliana Maia Teixeira, Kathleen Anne Sluka, Adair Roberto Soares Santo. Interleukin-4 mediates the analgesia produced by low-intensity exercise in mice with neuropathic pain. Pain. vol 159. issue 3. 2019-04-01. PMID:29140923. |
in the spinal cord, pni increased glial cell activation, brain-derived neurotrophic factor and β-nerve growth factor levels, and decreased il-4 and il-1ra levels, whereas treadmill exercise suppressed glial cells activation (glial fibrillary acidic protein and iba1 immunoreactivity), reduced brain-derived neurotrophic factor and β-nerve growth factor, and increased il-4, il-1ra, and il-5 concentrations. |
2019-04-01 |
2023-08-13 |
mouse |
Lifeng Qi, Xinhong Xue, Jijun Sun, Qingjian Wu, Hongru Wang, Yan Guo, Baoliang Su. The Promising Effects of Transplanted Umbilical Cord Mesenchymal Stem Cells on the Treatment in Traumatic Brain Injury. The Journal of craniofacial surgery. vol 29. issue 7. 2018-12-20. PMID:30234712. |
simultaneously, the expression of glial cell line-derived neurotrophic factor (gdnf) and brain derived neurotrophic factor (bdnf) were measured by real-time-polymerase chain reaction and elisa.the authors found that the group of transplantation uc-mscs has a significant improvement than other group treated by phosphate buffered saline. |
2018-12-20 |
2023-08-13 |
rat |
Daniela Impellizzeri, Marika Cordaro, Giuseppe Bruschetta, Rosalba Siracusa, Rosalia Crupi, Emanuela Esposito, Salvatore Cuzzocre. N-Palmitoylethanolamine-Oxazoline as a New Therapeutic Strategy to Control Neuroinflammation: Neuroprotective Effects in Experimental Models of Spinal Cord and Brain Injury. Journal of neurotrauma. vol 34. issue 18. 2018-05-21. PMID:28095731. |
in addition, the expression of neurotrophic factors, such as glial cell line-derived neurotrophic factor, brain-derived neurotrophic factor, and neurotrophin-3 were increased by pea-oxa treatment. |
2018-05-21 |
2023-08-13 |
mouse |
Wenhuan Xiao, Fei Ye, Chunlai Liu, Xiaowei Tang, Jin Li, Hui Dong, Weiwei Sha, Xiaobin Zhan. Cognitive impairment in first-episode drug-naïve patients with schizophrenia: Relationships with serum concentrations of brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor. Progress in neuro-psychopharmacology & biological psychiatry. vol 76. 2018-04-02. PMID:28342945. |
cognitive impairment in first-episode drug-naïve patients with schizophrenia: relationships with serum concentrations of brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor. |
2018-04-02 |
2023-08-13 |
Not clear |
Suman Mishra, Rajnikant Mishr. Tolerance of hyperammonemia in brain of Heteropneustes fossilis is supported by glutamate-glutamine cycle. Journal of chemical neuroanatomy. vol 80. 2018-02-20. PMID:27913184. |
the expression patterns of genes associated to homeostasis of neuron and glia, management of oxidative stress and inflammation, ammonia metabolism and brain derived neurotrophic factor were analysed through reverse-transcriptase-polymerase chain reaction. |
2018-02-20 |
2023-08-13 |
Not clear |
André T R Goes, Cristiano R Jesse, Michelle S Antunes, Fernando V Lobo Ladd, Aliny A B Lobo Ladd, Cristiane Luchese, Natalia Paroul, Silvana P Boeir. Protective role of chrysin on 6-hydroxydopamine-induced neurodegeneration a mouse model of Parkinson's disease: Involvement of neuroinflammation and neurotrophins. Chemico-biological interactions. vol 279. 2018-01-03. PMID:29054324. |
6-ohda administration elevated levels of tumour necrosis factor-α, interferon-gamma, interleukin-1β, interleukin-2, interleukin-6 and nuclear factor-kappa b and decreased the interleukin-10 levels, total reactive antioxidant potential and total antioxidant reactivity in striatum, as well as, modified the calcium-binding protein b (s100b), brain-derived neurotrophic factor, nerve growth factor and glial cell line-derived neurotrophic factor levels. |
2018-01-03 |
2023-08-13 |
mouse |
Qian Yang, Yini Ke, Jianhong Luo, Yang Tan. Protocol for culturing low density pure rat hippocampal neurons supported by mature mixed neuron cultures. Journal of neuroscience methods. vol 277. 2017-11-16. PMID:27956052. |
this may be due to a lack of neurotrophic factors such as brain derived neurotrophic factor (bdnf), neurotrophin-3 (nt3) and glial cell line-derived neurotrophic factor (gdnf). |
2017-11-16 |
2023-08-13 |
rat |
Cho-Chen Hsieh, Muh-Shi Lin, Kuo-Feng Hua, Wei-Jung Chen, Chai-Ching Li. Neuroprotection by freshwater clam extract against the neurotoxin MPTP in C57BL/6 mice. Neuroscience letters. vol 642. 2017-09-08. PMID:28126590. |
the expressions of brain-derived neurotrophic factor, glial cell line-derived neurotrophic factor, and nerve growth factor were markedly increased by fce action against mptp-induced toxicity. |
2017-09-08 |
2023-08-13 |
mouse |
Beatrice Vignoli, Giulia Battistini, Riccardo Melani, Robert Blum, Spartaco Santi, Nicoletta Berardi, Marco Canoss. Peri-Synaptic Glia Recycles Brain-Derived Neurotrophic Factor for LTP Stabilization and Memory Retention. Neuron. vol 92. issue 4. 2017-07-26. PMID:27746130. |
peri-synaptic glia recycles brain-derived neurotrophic factor for ltp stabilization and memory retention. |
2017-07-26 |
2023-08-13 |
mouse |