Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
T L Bale, D M Dors. NGF, cyclic AMP, and phorbol esters regulate oxytocin receptor gene transcription in SK-N-SH and MCF7 cells. Brain research. Molecular brain research. vol 53. issue 1-2. 1998-04-20. PMID:9473629. |
receptor binding studies using the otr antagonist 125i-labeled ornithine vasotocin, and western blot analyses of otrs in mcf7 cells, showed that pma and forskolin also increased the density of endogenous human oxytocin receptors. |
1998-04-20 |
2023-08-12 |
human |
S Hyodo, S Ishii, J M Jos. Australian lungfish neurohypophysial hormone genes encode vasotocin and [Phe2]mesotocin precursors homologous to tetrapod-type precursors. Proceedings of the National Academy of Sciences of the United States of America. vol 94. issue 24. 1998-01-08. PMID:9371847. |
genomic sequence analysis and northern blot analysis confirmed that [phe2]mt is a native oxytocin family peptide in the australian lungfish, although it has been reported that the lungfish neurohypophysis contains mt. |
1998-01-08 |
2023-08-12 |
Not clear |
K Nishimori, L J Young, Q Guo, Z Wang, T R Insel, M M Matzu. Oxytocin is required for nursing but is not essential for parturition or reproductive behavior. Proceedings of the National Academy of Sciences of the United States of America. vol 93. issue 21. 1996-12-04. PMID:8876199. |
southern blot analysis of genomic dna from homozygote offspring and in situ hybridization with an exonic probe 3' of the deletion failed to detect any oxytocin or neurophysin sequences, respectively, confirming that the mutation was a null mutation. |
1996-12-04 |
2023-08-12 |
mouse |
H H Zingg, F Rozen, C Breton, A Larcher, J Neculcea, K Chu, C Russo, A Arsla. Gonadal steroid regulation of oxytocin and oxytocin receptor gene expression. Advances in experimental medicine and biology. vol 395. 1996-09-19. PMID:8713994. |
by northern blot analysis and in situ hybridization, we have determined that, at term, the rat uterine epithelium represents a major site of oxytocin (ot) gene expression. |
1996-09-19 |
2023-08-12 |
rat |
H Ungefroren, M Davidoff, R Ivel. Post-transcriptional block in oxytocin gene expression within the seminiferous tubules of the bovine testis. The Journal of endocrinology. vol 140. issue 1. 1994-04-25. PMID:8138753. |
northern blot hybridization showed that bovine and sheep testis, unlike testes from other mammals, contain moderate levels of an apparently normal oxytocin gene transcript. |
1994-04-25 |
2023-08-12 |
cattle |
E Mohr, S Fehr, D Richte. Axonal transport of neuropeptide encoding mRNAs within the hypothalamo-hypophyseal tract of rats. The EMBO journal. vol 10. issue 9. 1991-09-18. PMID:1868830. |
the concept of axonal mrna transport is supported firstly, by northern blot and in situ hybridization analysis indicating that vasopressin and oxytocin mrnas are also present in the neural stalk; secondly, by intron analysis and transcription run on experiments demonstrating the absence of primary vasopressin and oxytocin transcripts in non-neuronal cells of the posterior pituitary; thirdly, by embryonic developmental studies showing that appearance of vasopressin transcripts in the hypothalamus and the pituitary anlage is correlated. |
1991-09-18 |
2023-08-11 |
human |
R Chibbar, J G Toma, B F Mitchell, F D Mille. Regulation of neural oxytocin gene expression by gonadal steroids in pubertal rats. Molecular endocrinology (Baltimore, Md.). vol 4. issue 12. 1991-05-07. PMID:2082196. |
northern blot analysis demonstrated that neural oxytocin mrna increased 5- to 10-fold from postnatal day 20 (p20) to p60 in animals of both sexes, coincident with puberty. |
1991-05-07 |
2023-08-11 |
rat |
G F Jirikowski, P P Sanna, F E Bloo. mRNA coding for oxytocin is present in axons of the hypothalamo-neurohypophysial tract. Proceedings of the National Academy of Sciences of the United States of America. vol 87. issue 19. 1990-11-09. PMID:2268384. |
southern blot analysis of the amplification products confirmed the presence of oxytocin mrna in all three tissue samples. |
1990-11-09 |
2023-08-11 |
rat |
F D Miller, G Ozimek, R J Milner, F E Bloo. Regulation of neuronal oxytocin mRNA by ovarian steroids in the mature and developing hypothalamus. Proceedings of the National Academy of Sciences of the United States of America. vol 86. issue 7. 1989-05-05. PMID:2928343. |
northern blot analysis demonstrated a significant developmental increase in the abundance of oxytocin mrna in the female brain concomitant with puberty. |
1989-05-05 |
2023-08-11 |
rat |
G Almazan, D L Lefebvre, H H Zing. Ontogeny of hypothalamic vasopressin, oxytocin and somatostatin gene expression. Brain research. Developmental brain research. vol 45. issue 1. 1989-03-29. PMID:2563676. |
the expression of 3 neuropeptide genes, vasopressin (avp), oxytocin (ot) and somatostatin (som), was studied in the developing rat hypothalamus using northern blot analysis combined with densitometric scanning. |
1989-03-29 |
2023-08-11 |
rat |
U Nörenberg, A Brunath, D Richte. Expression of the bovine hypothalamic hormone oxytocin precursor in Escherichia coli. Biochimie. vol 70. issue 1. 1988-09-12. PMID:3135840. |
the oxytocin precursor was cleaved off the fusion protein by cyanogen bromide treatment, chromatographed on fplc columns and identified by western blot analysis, using antibodies raised against neurophysin. |
1988-09-12 |
2023-08-11 |
cattle |