| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| O Steward, M S Kelley, E R Torr. The process of reinnervation in the dentate gyrus of adult rats: temporal relationship between changes in the levels of glial fibrillary acidic protein (GFAP) and GFAP mRNA in reactive astrocytes. Experimental neurology. vol 124. issue 2. 1994-02-18. PMID:8287920. |
the dot blot analyses of gfap mrna levels confirmed previous studies, in that we observed dramatic increases in the levels of gfap mrna in the hippocampus ipsilateral to the ec lesions. |
1994-02-18 |
2023-08-12 |
rat |
| M D Browning, E M Dudek, J L Rapier, S Leonard, R Freedma. Significant reductions in synapsin but not synaptophysin specific activity in the brains of some schizophrenics. Biological psychiatry. vol 34. issue 8. 1994-02-08. PMID:8274580. |
the levels of the synaptic vesicle-associated proteins, synapsin and synaptophysin, were examined in human postmortem hippocampus from the brains of schizophrenics and age-matched controls using a quantitative western blot analysis. |
1994-02-08 |
2023-08-12 |
human |
| H Otsuki, K Yamada, T Yuguchi, M Taneda, T Hayakaw. Prostaglandin E1 induces c-Fos and Myc proteins and protects rat hippocampal cells against hypoxic injury. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 14. issue 1. 1994-01-25. PMID:8263051. |
western blot analysis showed an increased induction of 62-kda c-fos and 58, 60, and 66 kda myc proteins in rat hippocampal cells with 10(-7) m pge1 treatment. |
1994-01-25 |
2023-08-12 |
rat |
| D R Repaske, J G Corbin, M Conti, M F Go. A cyclic GMP-stimulated cyclic nucleotide phosphodiesterase gene is highly expressed in the limbic system of the rat brain. Neuroscience. vol 56. issue 3. 1994-01-13. PMID:8305078. |
northern blot analysis of brain subregions shows especially strong expression in hippocampus and cortex, modest expression in the remainder of the forebrain and in the midbrain, and little expression in cerebellum and hindbrain. |
1994-01-13 |
2023-08-12 |
rat |
| M V Sofroniew, J D Cooper, C N Svendsen, P Crossman, N Y Ip, R M Lindsay, F Zafra, D Lindhol. Atrophy but not death of adult septal cholinergic neurons after ablation of target capacity to produce mRNAs for NGF, BDNF, and NT3. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 12. 1994-01-12. PMID:8254373. |
after near complete ablation of hippocampal neurons, total levels of ngf, brain-derived neurotrophic factor (bdnf), and neurotrophin-3 (nt3) mrna measured by quantitative northern blot analysis in the hippocampal remnant fell significantly, to less than 25% of control values by 28 d and to less than 9% by 300 d. in the septal region ipsilateral to such lesions, ngf protein levels measured by elisa fell significantly, to about 35% of control values, but the number of immunohistochemically detected cholinergic neurons did not decline significantly for up to 500 d. instead, the cholinergic neurons persisted in an atrophied state, exhibiting severe shrinkage and reduced staining for the transmitter-synthesizing enzyme chat. |
1994-01-12 |
2023-08-12 |
rat |
| D J Bonthius, O Stewar. Induction of cortical spreading depression with potassium chloride upregulates levels of messenger RNA for glial fibrillary acidic protein in cortex and hippocampus: inhibition by MK-801. Brain research. vol 618. issue 1. 1993-11-15. PMID:8402181. |
intraperitoneal injection of mk-801, a non-competitive nmda antagonist which prevents spreading depression, blocked the upregulation of gfap mrna in both the hippocampus and the cortex, as demonstrated by both in situ and dot blot hybridization. |
1993-11-15 |
2023-08-12 |
Not clear |
| R V Bhat, F A Tausk, J M Baraban, R E Mains, B A Eippe. Rapid increases in peptide processing enzyme expression in hippocampal neurons. Journal of neurochemistry. vol 61. issue 4. 1993-10-21. PMID:8397292. |
after a single ect, in situ hybridization demonstrated a rapid increase in the level of pam mrna in the dentate granule cells of the hippocampus, reaching peak levels between 1 and 4 h and then returning to near baseline levels within 24 h. northern blot analysis confirmed the changes in pam mrna expression seen by using in situ hybridization. |
1993-10-21 |
2023-08-12 |
rat |
| M Ruat, E Traiffort, R Leurs, J Tardivel-Lacombe, J Diaz, J M Arrang, J C Schwart. Molecular cloning, characterization, and localization of a high-affinity serotonin receptor (5-HT7) activating cAMP formation. Proceedings of the National Academy of Sciences of the United States of America. vol 90. issue 18. 1993-10-20. PMID:8397408. |
northern blot and in situ hybridization analyses showed the 5-ht7 transcripts to be expressed in discrete areas of the limbic brain (e.g., pyramidal hippocampus cells, tenia tecta, amygdaloid, or mammillary nuclei), suggesting that the receptor mediates serotoninergic controls in functions like mood, learning, or neuroendocrine and vegetative behaviors. |
1993-10-20 |
2023-08-12 |
Not clear |
| B Schöbitz, F Holsboer, R Kikkert, W Sutanto, E R De Kloe. Peripheral and central regulation of IL-6 gene expression in endotoxin-treated rats. Endocrine regulations. vol 26. issue 3. 1993-09-30. PMID:1308153. |
subsequently, northern blot analyses were performed with rna isolated from spleen, adrenals, pituitary gland, hypothalamus, hippocampus and cerebellum of rats injected intraperitoneally with a non toxic dose of lps. |
1993-09-30 |
2023-08-11 |
rat |
| A Takeda, H Onodera, A Sugimoto, K Kogure, M Obinata, S Shibahar. Coordinated expression of messenger RNAs for nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 in the rat hippocampus following transient forebrain ischemia. Neuroscience. vol 55. issue 1. 1993-09-15. PMID:8350988. |
changes in nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 messenger rna expression in the rat hippocampus following 20 min of transient forebrain ischemia were evaluated using northern blot analysis and in situ hybridization histochemistry. |
1993-09-15 |
2023-08-12 |
rat |
| L L Demchyshyn, C B Srikant, R K Sunahara, G Kent, P Seeman, H H Van Tol, R Panetta, Y C Patel, H B Nizni. Cloning and expression of a human somatostatin-14-selective receptor variant (somatostatin receptor 4) located on chromosome 20. Molecular pharmacology. vol 43. issue 6. 1993-07-23. PMID:8100352. |
northern blot analysis revealed the presence of an sstr4 mrna species of approximately 4 kilobases in select regions of the monkey brain, including the hippocampus, hypothalamus, cortex, and striatum, with little or no receptor mrna detected in either the olfactory tubercle, medulla, cerebellum, or amygdala. |
1993-07-23 |
2023-08-12 |
human |
| J Gómez-Márquez, J I Pedrares, A Otero, R Anadó. Prominent expression of the actin-sequestering peptide Fx gene in the hippocampal region of rat brain. Neuroscience letters. vol 152. issue 1-2. 1993-07-19. PMID:8515877. |
northern blot analysis confirmed the prominent expression of the fx transcript in the hippocampus and showed a notably lower amount of this mrna in the hippocampus of old rats suggesting an influence of aging on the expression of this gene. |
1993-07-19 |
2023-08-12 |
rat |
| F Y Sun, E Costa, I Mocchett. Adrenal steroids mediate the increase of hippocampal nerve growth factor biosynthesis following bicuculline convulsions. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 8. issue 3. 1993-07-12. PMID:8507349. |
northern blot analysis of nerve growth factor (ngf) messenger ribonucleic acid (mrna), together with a two-site enzyme immunoassay for ngf protein, showed that a convulsive dose of bicuculline (0.4 mg/kg, iv) induced a rapid (within 1 hour) three-fold increase in hippocampal ngf mrna. |
1993-07-12 |
2023-08-12 |
rat |
| M Ruat, E Traiffort, J M Arrang, J Tardivel-Lacombe, J Diaz, R Leurs, J C Schwart. A novel rat serotonin (5-HT6) receptor: molecular cloning, localization and stimulation of cAMP accumulation. Biochemical and biophysical research communications. vol 193. issue 1. 1993-07-01. PMID:8389146. |
the highest expression, detected by northern blot analysis as well as by in situ hybridization occurs in various serotoninergic areas of rat or guinea pig brain such as striatum, olfactory tubercle, nucleus accumbens and hippocampus, but a faint expression is also detectable in rat stomach. |
1993-07-01 |
2023-08-12 |
rat |
| P A Lapchak, D M Araujo, K D Beck, C E Finch, S A Johnson, F Heft. BDNF and trkB mRNA expression in the hippocampal formation of aging rats. Neurobiology of aging. vol 14. issue 2. 1993-06-10. PMID:8487914. |
northern blot analysis of hippocampal rna from male fischer 344 confirmed that neither bdnf mrna nor trkb mrna levels changed with age. |
1993-06-10 |
2023-08-12 |
rat |
| J D Corness, L L Demchyshyn, P Seeman, H H Van Tol, C B Srikant, G Kent, Y C Patel, H B Nizni. A human somatostatin receptor (SSTR3), located on chromosome 22, displays preferential affinity for somatostatin-14 like peptides. FEBS letters. vol 321. issue 2-3. 1993-05-26. PMID:8097479. |
northern blot analysis reveals the presence of an sstr3 mrna species of approximately 5 kb in various regions of the monkey brain, including the frontal cortex, cerebellum, medulla, amygdala, with little or no sstr3 mrna detectable in brain regions such as the striatum, hippocampus, and olfactory tubercle. |
1993-05-26 |
2023-08-12 |
human |
| P A Lapchak, D M Araujo, F Heft. Cholinergic regulation of hippocampal brain-derived neurotrophic factor mRNA expression: evidence from lesion and chronic cholinergic drug treatment studies. Neuroscience. vol 52. issue 3. 1993-04-15. PMID:8450959. |
quantitative in situ hybridization and northern blot analysis techniques were used to determine the effects of removal of the cholinergic input on levels and topographical distribution of brain-derived neurotrophic factor mrna in the hippocampus of adult rats. |
1993-04-15 |
2023-08-12 |
rat |
| P A Lapchak, D M Araujo, F Heft. Cholinergic regulation of hippocampal brain-derived neurotrophic factor mRNA expression: evidence from lesion and chronic cholinergic drug treatment studies. Neuroscience. vol 52. issue 3. 1993-04-15. PMID:8450959. |
quantitative northern blot analysis indicated that hippocampal bdnf mrna was decreased by 29 and 68%, three weeks after partial or full unilateral fimbrial transections, respectively. |
1993-04-15 |
2023-08-12 |
rat |
| S R D'Mello, C Jiang, C Lamberti, S C Martin, G Heinric. Differential regulation of the nerve growth factor and brain-derived neurotrophic factor genes in L929 mouse fibroblasts. Journal of neuroscience research. vol 33. issue 4. 1993-02-12. PMID:1336558. |
northern blot hybridization analysis revealed 4 discrete bdnf mrna species in l929 cells and rat hippocampus after induction of seizures with kainic acid. |
1993-02-12 |
2023-08-11 |
mouse |
| M Kobayashi, K Takamatsu, S Saitoh, M Miura, T Noguch. Molecular cloning of hippocalcin, a novel calcium-binding protein of the recoverin family exclusively expressed in hippocampus. Biochemical and biophysical research communications. vol 189. issue 1. 1992-12-30. PMID:1280427. |
northern blot, in situ hybridization, immunoblot and immunohistochemical analyses revealed that the protein is exclusively expressed in pyramidal layer of the hippocampus. |
1992-12-30 |
2023-08-11 |
rat |