| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yu Song, Taizhen Cui, Na Xie, Xiaoyi Zhang, Zhibin Qian, Juyuan Li. Protocatechuic acid improves cognitive deficits and attenuates amyloid deposits, inflammatory response in aged AβPP/PS1 double transgenic mice. International immunopharmacology. vol 20. issue 1. 2014-12-28. PMID:24667368. |
pca could significantly reduce the number of aβ positive expressions in the hippocampus and cerebral cortex of aβpp/ps1 mice by immunocytochemical assay with congo red staining and decrease remarkably app expression level by western blot analysis (p<0.01). |
2014-12-28 |
2023-08-12 |
mouse |
| Jiahui Mao, Yae Hu, Ailing Zhou, Bing Zheng, Yi Liu, Yueming Du, Jia Li, Jinyang Lu, Pengcheng Zho. Oxymatrine reduces neuroinflammation in rat brain: A signaling pathway. Neural regeneration research. vol 7. issue 30. 2014-12-24. PMID:25538757. |
twenty-four hours after model induction, the hippocampus was analyzed by real-time quantitative pcr, and the cerebral cortex was analyzed by enzyme-linked immunosorbent assay and western blot assay. |
2014-12-24 |
2023-08-13 |
rat |
| Aleksandra N Mladenovic Djordjevic, Milka Perovic, Kosara Smiljanic, Smilja Todorovic, Vesna Tesic, Sabera Ruzdijic, Selma Kanazi. The effects of dietary restriction and aging on amyloid precursor protein and presenilin-1 mRNA and protein expression in rat brain. Neuroreport. vol 25. issue 6. 2014-12-23. PMID:24346258. |
changes in mrna and protein expression were assessed by real-time pcr and western blot analysis during aging and long-term dr in the cortex and hippocampus of 6-, 12-, 18-, and 24-month-old rats. |
2014-12-23 |
2023-08-12 |
rat |
| Wen-Xian Huang, Jia-Wei Min, Yu-Qiang Liu, Xiao-Hua He, Bi-Wen Pen. Expression of TRPV1 in the C57BL/6 mice brain hippocampus and cortex during development. Neuroreport. vol 25. issue 6. 2014-12-23. PMID:24488030. |
here, we reveal that the expression of trpv1 can be detected in the c57bl/6 mouse hippocampus and cortex using real-time pcr and western blot. |
2014-12-23 |
2023-08-12 |
mouse |
| Haiyang Yu, Tingting Li, Yan Cui, Yingjun Liao, Gaoyang Wang, Lanyue Gao, Fenghong Zhao, Yaping Ji. Effects of lead exposure on D-serine metabolism in the hippocampus of mice at the early developmental stages. Toxicology. vol 325. 2014-12-18. PMID:25242007. |
expressions of serine racemase (sr), d-amino acid oxidase (daao), alanine-serine- cysteine transporter-1 (asc-1) and subunits of n-methyl-d-aspartate receptor (nmdar) in the hippocampus of pnd 10, 20 and 40 mice were examined by western blot and real time rt-pcr. |
2014-12-18 |
2023-08-13 |
mouse |
| Rasoul Ghasemi, Asadollah Zarifkar, Karim Rastegar, Nader Maghsoudi, Maryam Moosav. Repeated intra-hippocampal injection of beta-amyloid 25–35 induces a reproducible impairment of learning and memory: considering caspase-3 and MAPKs activity. European journal of pharmacology. vol 726. 2014-12-15. PMID:24418687. |
hippocampal western blot analysis revealed that behavioral impairment is in parallel with greater apoptosis and mapks activation. |
2014-12-15 |
2023-08-12 |
rat |
| D Feng, W Wang, Y Dong, L Wu, J Huang, Y Ma, Z Zhang, S Wu, G Gao, H Qi. Ceftriaxone alleviates early brain injury after subarachnoid hemorrhage by increasing excitatory amino acid transporter 2 expression via the PI3K/Akt/NF-κB signaling pathway. Neuroscience. vol 268. 2014-12-12. PMID:24631672. |
terminal deoxynucleotidyl transferase-mediated dutp-biotin nick end labeling assay (tunel) staining and western blot analysis of cleaved caspase 3 showed that cef decreased hippocampal neuronal apoptosis following sah. |
2014-12-12 |
2023-08-12 |
rat |
| Jiaqing Yang, Shilei Song, Jian Li, Tao Lian. Neuroprotective effect of curcumin on hippocampal injury in 6-OHDA-induced Parkinson's disease rat. Pathology, research and practice. vol 210. issue 6. 2014-12-12. PMID:24642369. |
furthermore, curcumin obviously up-regulated hippocampal brain derived neurotrophic factor (bdnf), trkb, phosphatidylinositide 3-kinases (pi3k) protein expressions, respectively as shown in western blot analysis. |
2014-12-12 |
2023-08-12 |
rat |
| Fangli Liu, Zhenfei Xue, Ning Li, Hui Huang, Yanyan Ying, Jin Li, Lin Wang, Wenjie L. Effects of lead exposure on the expression of amyloid β and phosphorylated tau proteins in the C57BL/6 mouse hippocampus at different life stages. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). vol 28. issue 2. 2014-12-03. PMID:24582137. |
the protein expression of amyloid β and phosphorylated tau in the hippocampus was detected via western blot. |
2014-12-03 |
2023-08-12 |
mouse |
| Michael A van der Kooij, Martina Fantin, Igor Kraev, Irina Korshunova, Jocelyn Grosse, Olivia Zanoletti, Ramon Guirado, Clara Garcia-Mompó, Juan Nacher, Michael G Stewart, Vladimir Berezin, Carmen Sand. Impaired hippocampal neuroligin-2 function by chronic stress or synthetic peptide treatment is linked to social deficits and increased aggression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 5. 2014-12-01. PMID:24213355. |
this occurs along with a reduction of nlgn-2, but not nlgn-1 expression (as shown with western blot, immunohistochemistry, and electron microscopy analyses), throughout the hippocampus and detectable in different layers of the ca1, ca3, and dg subfields. |
2014-12-01 |
2023-08-12 |
rat |
| Ying Li Gu, Li Wei Zhang, Ning Ma, Lin Lin Ye, De Xin Wang, Xu Ga. Cognitive improvement of mice induced by exercise prior to traumatic brain injury is associated with cytochrome c oxidase. Neuroscience letters. vol 570. 2014-12-01. PMID:24746931. |
using western blot, the expressions of cox i, ii, iii, bdnf, synapsin i, synaptophysin (syp) and gap43 in hippocampus of tbi mice were determinated. |
2014-12-01 |
2023-08-13 |
mouse |
| Bing Chun Yan, Joon Ha Park, Bai Hui Chen, Jeong-Hwi Cho, In Hye Kim, Ji Hyeon Ahn, Jae-Chul Lee, In Koo Hwang, Jun Hwi Cho, Yun Lyul Lee, Il-Jun Kang, Moo-Ho Wo. Long-term administration of scopolamine interferes with nerve cell proliferation, differentiation and migration in adult mouse hippocampal dentate gyrus, but it does not induce cell death. Neural regeneration research. vol 9. issue 19. 2014-11-25. PMID:25422633. |
in this study, we used immunohistochemistry and western blot methods to weekly detect the biological behaviors of nerve cells in the hippocampal dentate gyrus of adult mice that received intraperitoneal administration of scopolamine for 4 weeks. |
2014-11-25 |
2023-08-13 |
mouse |
| Félix Luis Núñez-Santana, Myongsoo Matthew Oh, Marcia Diana Antion, Amy Lee, Johannes Wilhelm Hell, John Francis Disterhof. Surface L-type Ca2+ channel expression levels are increased in aged hippocampus. Aging cell. vol 13. issue 1. 2014-11-21. PMID:24033980. |
western blot analysis of the total expression levels revealed significant reductions in both cav 1.2 and cav 1.3 subunits from all three major hippocampal regions of aged rats. |
2014-11-21 |
2023-08-12 |
rat |
| Rosalia Crupi, Irene Paterniti, Akbar Ahmad, Michela Campolo, Emanuela Esposito, Salvatore Cuzzocre. Effects of palmitoylethanolamide and luteolin in an animal model of anxiety/depression. CNS & neurological disorders drug targets. vol 12. issue 7. 2014-11-12. PMID:23844686. |
adult hippocampal neurogenesis and neuroplasticity were evaluated by immunohistochemical techniques; brain-derived neurotrophic factor and apoptotic protein (bax and bcl2) expression were studied by immunostaining and western blot analysis. |
2014-11-12 |
2023-08-12 |
mouse |
| Carlos D Gómez, Rudolf M Buijs, María Sitge. The anti-seizure drugs vinpocetine and carbamazepine, but not valproic acid, reduce inflammatory IL-1β and TNF-α expression in rat hippocampus. Journal of neurochemistry. vol 130. issue 6. 2014-10-30. PMID:24903676. |
in the present study, the effects of the two classical anti-epileptic drugs, carbamazepine and valproic acid, and the non-classical anti-seizure drug vinpocetine were investigated on the expression of the pro-inflammatory cytokines il-1β and tnf-α in the hippocampus of rats by pcr or western blot after the administration of one or seven doses. |
2014-10-30 |
2023-08-13 |
rat |
| Qin Zhang, Xiaohong Xu, Tao Li, Yang Lu, Qin Ruan, Yingjun Lu, Qinwen Wang, Fangni Dong, Yanling Yang, Guangxia Zhan. Exposure to bisphenol-A affects fear memory and histone acetylation of the hippocampus in adult mice. Hormones and behavior. vol 65. issue 2. 2014-10-20. PMID:24333847. |
furthermore, western blot analyses showed that bpa exposure decreased the level of n-methyl-d-aspartic acid (nmda) receptor subunit nr1 and increased the expression of histone deacetylase 2 (hdac2) before fear conditioning training in the hippocampus of male mice. |
2014-10-20 |
2023-08-12 |
mouse |
| Nan Hu, Dongyong Guo, Haiyun Wang, Keliang Xie, Chao Wang, Yize Li, Chunyan Wang, Chenxu Wang, Yonghao Yu, Guolin Wan. Involvement of the blood-brain barrier opening in cognitive decline in aged rats following orthopedic surgery and high concentration of sevoflurane inhalation. Brain research. vol 1551. 2014-10-15. PMID:24440777. |
alterations of tight junctions in hippocampus were measured with occludin and claudin-5 western blot. |
2014-10-15 |
2023-08-12 |
rat |
| Feng Jia, Qing Mao, Yu-Min Liang, Ji-Yao Jian. The effect of hypothermia on the expression of TIMP-3 after traumatic brain injury in rats. Journal of neurotrauma. vol 31. issue 4. 2014-10-06. PMID:23256480. |
according to the rt-pcr and western blot analyses, the maximum mrna levels of timp-3 were reduced to 60.60 ± 2.30%, 55.83 ± 1.80%, 66.03 ± 2.10%, and 64.51 ± 1.50%, respectively, of the corresponding values in the normothermic group in the injured and uninjured hemispheres (cortex and hippocampus) of the hypothermia group (p < 0.01), while the respective maximum protein levels of timp-3 were reduced to 57.50 ± 1.50, 52.67 ± 2.20, 60.31 ± 2.50 and 54.76 ± 1.40 (p < 0.01). |
2014-10-06 |
2023-08-12 |
rat |
| Takayuki Nakajima, Masafumi Yanagihara, Hideki Nishi. Temporal and regional patterns of Smad activation in the rat hippocampus following global ischemia. Journal of the neurological sciences. vol 337. issue 1-2. 2014-10-06. PMID:24290497. |
we found that 1) smad1, -2, -3, and -5 proteins were detected in the rat hippocampus by means of western blot and immunohistochemistry; 2) after 5 min of ischemia, smad2 and smad3 proteins accumulated in the nuclei of pyramidal cells in the ca1 region, which is vulnerable to ischemia; 3) after 3 min of ischemia, which was non-lethal, there was no such nuclear accumulation of smad2 and smad3 in the ca1 region; 4) following injection of activin a, nuclear accumulation of smad2 and smad3 was induced not only in pyramidal cells of the ca1 region, but also in pyramidal cells of the ca3 region as well as in granule cells of the dg region; 5) activin a-induced nuclear accumulation of smad2 and smad3 neither caused degeneration of hippocampal neurons nor prevented degeneration induced by ischemia. |
2014-10-06 |
2023-08-12 |
rat |
| Hui Li, Zhong-Liang Zhu, Ning Jia, Zhuan-Li Bai, Qing Cai, Rui Chen, Tian-Bao Song, Jian-Kang Li. [Gender-dependent difference of NF-kappaB expression in the hippocampus of prenatally stressed offspring rats]. Sheng li xue bao : [Acta physiologica Sinica]. vol 58. issue 6. 2014-09-26. PMID:17173193. |
in this study, immunohistochemistry and western blot were used to determine whether the expression of nf-kappab in the hippocampus of prenatally stressed offspring rats is gender-dependent. |
2014-09-26 |
2023-08-12 |
rat |