| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Scott E Kanoski, Robert L Meisel, Amanda J Mullins, Terry L Davidso. The effects of energy-rich diets on discrimination reversal learning and on BDNF in the hippocampus and prefrontal cortex of the rat. Behavioural brain research. vol 182. issue 1. 2007-10-12. PMID:17590450. |
the effects of energy-rich diets on discrimination reversal learning and on bdnf in the hippocampus and prefrontal cortex of the rat. |
2007-10-12 |
2023-08-12 |
rat |
| Scott E Kanoski, Robert L Meisel, Amanda J Mullins, Terry L Davidso. The effects of energy-rich diets on discrimination reversal learning and on BDNF in the hippocampus and prefrontal cortex of the rat. Behavioural brain research. vol 182. issue 1. 2007-10-12. PMID:17590450. |
we evaluated the effects of these dietary manipulations on discrimination and reversal performance and on post-training levels of brain-derived neurotrophic factor (bdnf) in the prefrontal cortex and the ventral and dorsal hippocampus. |
2007-10-12 |
2023-08-12 |
rat |
| Scott E Kanoski, Robert L Meisel, Amanda J Mullins, Terry L Davidso. The effects of energy-rich diets on discrimination reversal learning and on BDNF in the hippocampus and prefrontal cortex of the rat. Behavioural brain research. vol 182. issue 1. 2007-10-12. PMID:17590450. |
however, prior unrestricted access to the hfd diet impaired discrimination reversal learning and reduced bdnf in the prefrontal cortex and ventral hippocampus. |
2007-10-12 |
2023-08-12 |
rat |
| Timothy W Bredy, Hao Wu, Cortney Crego, Jessica Zellhoefer, Yi E Sun, Mark Bara. Histone modifications around individual BDNF gene promoters in prefrontal cortex are associated with extinction of conditioned fear. Learning & memory (Cold Spring Harbor, N.Y.). vol 14. issue 4. 2007-07-03. PMID:17522015. |
histone modifications around individual bdnf gene promoters in prefrontal cortex are associated with extinction of conditioned fear. |
2007-07-03 |
2023-08-12 |
human |
| Timothy W Bredy, Hao Wu, Cortney Crego, Jessica Zellhoefer, Yi E Sun, Mark Bara. Histone modifications around individual BDNF gene promoters in prefrontal cortex are associated with extinction of conditioned fear. Learning & memory (Cold Spring Harbor, N.Y.). vol 14. issue 4. 2007-07-03. PMID:17522015. |
here, we report that extinction of conditioned fear is accompanied by a significant increase in histone h4 acetylation around the bdnf p4 gene promoter and increases in bdnf exon i and iv mrna expression in prefrontal cortex, that vpa enhances long-term memory for extinction because of its hdac inhibitor effects, and that vpa potentiates the effect of weak extinction training on histone h4 acetylation around both the bdnf p1 and p4 gene promoters and on bdnf exon iv mrna expression. |
2007-07-03 |
2023-08-12 |
human |
| Eero Castrén, Vootele Võikar, Tomi Rantamäk. Role of neurotrophic factors in depression. Current opinion in pharmacology. vol 7. issue 1. 2007-04-12. PMID:17049922. |
essentially all antidepressant treatments increase bdnf synthesis and signaling in the hippocampus and prefrontal cortex. |
2007-04-12 |
2023-08-12 |
Not clear |
| Ronald S Duman, Lisa M Monteggi. A neurotrophic model for stress-related mood disorders. Biological psychiatry. vol 59. issue 12. 2006-09-07. PMID:16631126. |
decreased levels of bdnf, as well as other neurotrophic factors, could contribute to the atrophy of certain limbic structures, including the hippocampus and prefrontal cortex that has been observed in depressed subjects. |
2006-09-07 |
2023-08-12 |
human |
| Maribel Rios, Evelyn K Lambe, Rongjian Liu, Sarah Teillon, JinHong Liu, Schahram Akbarian, Suzanne Roffler-Tarlov, Rudolf Jaenisch, George K Aghajania. Severe deficits in 5-HT2A -mediated neurotransmission in BDNF conditional mutant mice. Journal of neurobiology. vol 66. issue 4. 2006-04-28. PMID:16408297. |
further analysis showed that bdnf mutants had much reduced 5-ht2a receptor protein in dorsal raphe nucleus and a similar deficit in prefrontal cortex, a region that normally shows a high level of 5-ht2a receptor expression. |
2006-04-28 |
2023-08-12 |
mouse |
| Takanori Hashimoto, David A Lewi. BDNF Val66Met polymorphism and GAD67 mRNA expression in the prefrontal cortex of subjects with schizophrenia. The American journal of psychiatry. vol 163. issue 3. 2006-04-25. PMID:16513879. |
bdnf val66met polymorphism and gad67 mrna expression in the prefrontal cortex of subjects with schizophrenia. |
2006-04-25 |
2023-08-12 |
human |
| Takanori Hashimoto, David A Lewi. BDNF Val66Met polymorphism and GAD67 mRNA expression in the prefrontal cortex of subjects with schizophrenia. The American journal of psychiatry. vol 163. issue 3. 2006-04-25. PMID:16513879. |
in the prefrontal cortex of subjects with schizophrenia, decreased signaling mediated by brain-derived neurotrophic factor (bdnf) and its receptor tyrosine kinase (trkb) appears to contribute to the reduced expression of mrna encoding the 67-kilodalton isoform of glutamate decarboxylase (gad(67)), an enzyme for gaba synthesis. |
2006-04-25 |
2023-08-12 |
human |
| Robnet T Kerns, Ajay Ravindranathan, Sajida Hassan, Mary P Cage, Tim York, James M Sikela, Robert W Williams, Michael F Mile. Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 9. 2006-03-31. PMID:15745951. |
ethanol-regulated genes were generally related to neuroplasticity, but regulation of discrete functional groups and pathways was brain region specific: glucocorticoid signaling, neurogenesis, and myelination in the prefrontal cortex; neuropeptide signaling and developmental genes, including factor bdnf, in the nucleus accumbens; and retinoic acid signaling in the ventral tegmental area. |
2006-03-31 |
2023-08-12 |
mouse |
| Sondra T Bland, Megan J Schmid, Andre Der-Avakian, Linda R Watkins, Robert L Spencer, Steven F Maie. Expression of c-fos and BDNF mRNA in subregions of the prefrontal cortex of male and female rats after acute uncontrollable stress. Brain research. vol 1051. issue 1-2. 2005-11-15. PMID:15993862. |
expression of c-fos and bdnf mrna in subregions of the prefrontal cortex of male and female rats after acute uncontrollable stress. |
2005-11-15 |
2023-08-12 |
rat |
| Takanori Hashimoto, Sarah E Bergen, Quyen L Nguyen, Baoji Xu, Lisa M Monteggia, Joseph N Pierri, Zhuoxin Sun, Allan R Sampson, David A Lewi. Relationship of brain-derived neurotrophic factor and its receptor TrkB to altered inhibitory prefrontal circuitry in schizophrenia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 2. 2005-08-17. PMID:15647480. |
in 15 pairs of subjects with schizophrenia and matched control subjects, both bdnf and trkb mrna levels, as assessed by in situ hybridization, were significantly decreased in the pfc of the subjects with schizophrenia, whereas the levels of mrna encoding the receptor tyrosine kinase for neurotrophin-3, trkc, were unchanged. |
2005-08-17 |
2023-08-12 |
mouse |
| Takanori Hashimoto, Sarah E Bergen, Quyen L Nguyen, Baoji Xu, Lisa M Monteggia, Joseph N Pierri, Zhuoxin Sun, Allan R Sampson, David A Lewi. Relationship of brain-derived neurotrophic factor and its receptor TrkB to altered inhibitory prefrontal circuitry in schizophrenia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 2. 2005-08-17. PMID:15647480. |
neither bdnf nor trkb mrna levels were changed in the pfc of monkeys after a long-term exposure to haloperidol. |
2005-08-17 |
2023-08-12 |
mouse |
| Takanori Hashimoto, Sarah E Bergen, Quyen L Nguyen, Baoji Xu, Lisa M Monteggia, Joseph N Pierri, Zhuoxin Sun, Allan R Sampson, David A Lewi. Relationship of brain-derived neurotrophic factor and its receptor TrkB to altered inhibitory prefrontal circuitry in schizophrenia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 2. 2005-08-17. PMID:15647480. |
genetically introduced decreases in trkb expression, but not in bdnf expression, also resulted in decreased gad67 and pv mrna levels in the pfc of adult mice; in addition, the cellular pattern of altered gad67 mrna expression paralleled that present in schizophrenia. |
2005-08-17 |
2023-08-12 |
mouse |
| Félicien Karege, Geneviève Vaudan, Michèle Schwald, Nader Perroud, Romano La Harp. Neurotrophin levels in postmortem brains of suicide victims and the effects of antemortem diagnosis and psychotropic drugs. Brain research. Molecular brain research. vol 136. issue 1-2. 2005-08-02. PMID:15893584. |
results indicated a significant decrease in bdnf and nt-3 levels in the hippocampus and pfc (only bdnf) but not in the entorhinal cortex, of suicide victims who were drug-free compared with non-suicide controls. |
2005-08-02 |
2023-08-12 |
human |
| Justin J Hill, Nutan Kolluri, Takanori Hashimoto, Qiang Wu, Allan R Sampson, Lisa M Monteggia, David A Lewi. Analysis of pyramidal neuron morphology in an inducible knockout of brain-derived neurotrophic factor. Biological psychiatry. vol 57. issue 8. 2005-05-16. PMID:15820715. |
the messenger ribonucleic acid (mrna) for brain-derived neurotrophic factor (bdnf), a regulator of pyramidal neuron dendritic spine density during development, is decreased in the prefrontal cortex of subjects with schizophrenia, and the level of bdnf mrna expression is positively correlated with dendritic spine density in the same subjects. |
2005-05-16 |
2023-08-12 |
human |
| Bernard Le Foll, Jorge Diaz, Pierre Sokolof. A single cocaine exposure increases BDNF and D3 receptor expression: implications for drug-conditioning. Neuroreport. vol 16. issue 2. 2005-04-14. PMID:15671872. |
acute cocaine produced a transient increase in bdnf mrna in the prefrontal cortex, associated with a long-lasting increase in drd3 mrna, and a delayed and long-lasting increase in drd3 protein in the nucleus accumbens. |
2005-04-14 |
2023-08-12 |
rat |
| Fabio Fumagalli, Francesco Bedogni, Jorge Perez, Giorgio Racagni, Marco Andrea Riv. Corticostriatal brain-derived neurotrophic factor dysregulation in adult rats following prenatal stress. The European journal of neuroscience. vol 20. issue 5. 2004-11-09. PMID:15341606. |
the main finding is that bdnf expression is reduced in the prefrontal cortex and striatum of prenatally stressed rats. |
2004-11-09 |
2023-08-12 |
rat |
| Maree J Webster, Cynthia Shannon Weickert, Mary M Herman, Joel E Kleinma. BDNF mRNA expression during postnatal development, maturation and aging of the human prefrontal cortex. Brain research. Developmental brain research. vol 139. issue 2. 2003-04-02. PMID:12480128. |
bdnf mrna expression during postnatal development, maturation and aging of the human prefrontal cortex. |
2003-04-02 |
2023-08-12 |
human |