| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Tang, Y Hou, H Wang, K Wang, H Xiang, X Wan, Y Xia, J Li, W Wei, S Xu, Z Lei, T M Pawlik, H Wang, M Wu, F She. Aspartate β-hydroxylase disrupts mitochondrial DNA stability and function in hepatocellular carcinoma. Oncogenesis. vol 6. issue 7. 2020-10-01. PMID:28714949. |
our previous study demonstrated an increased expression of aspartate β-hydroxylase (asph) in hcc tissues, which was associated with tumor invasiveness and a worse prognosis. |
2020-10-01 |
2023-08-13 |
Not clear |
| Yoshifumi Iwagami, Sarah Casulli, Katsuya Nagaoka, Miran Kim, Rolf I Carlson, Kosuke Ogawa, Michael S Lebowitz, Steve Fuller, Biswajit Biswas, Solomon Stewart, Xiaoqun Dong, Hossein Ghanbari, Jack R Wand. Lambda phage-based vaccine induces antitumor immunity in hepatocellular carcinoma. Heliyon. vol 3. issue 9. 2020-09-30. PMID:28971150. |
aspartate β-hydroxylase (asph) is a highly conserved enzyme overexpressed on the cell surface of both murine and human hcc cells. |
2020-09-30 |
2023-08-13 |
human |
| Kosuke Ogawa, Qiushi Lin, Le Li, Xuewei Bai, Xuesong Chen, Hua Chen, Rui Kong, Yongwei Wang, Hong Zhu, Fuliang He, Qinggang Xu, Lianxin Liu, Min Li, Songhua Zhang, Katsuya Nagaoka, Rolf Carlson, Howard Safran, Kevin Charpentier, Bei Sun, Jack Wands, Xiaoqun Don. Aspartate β-hydroxylase promotes pancreatic ductal adenocarcinoma metastasis through activation of SRC signaling pathway. Journal of hematology & oncology. vol 12. issue 1. 2020-07-06. PMID:31888763. |
aspartate β-hydroxylase (asph) drives embryonic cell motility/invasion in pancreatic development/differentiation. |
2020-07-06 |
2023-08-13 |
Not clear |
| Qiushi Lin, Xuesong Chen, Fanzheng Meng, Kosuke Ogawa, Min Li, Ruipeng Song, Shugeng Zhang, Ziran Zhang, Xianglu Kong, Qinggang Xu, Fuliang He, Xuewei Bai, Bei Sun, Mien-Chie Hung, Lianxin Liu, Jack Wands, Xiaoqun Don. ASPH-notch Axis guided Exosomal delivery of Prometastatic Secretome renders breast Cancer multi-organ metastasis. Molecular cancer. vol 18. issue 1. 2020-04-15. PMID:31694640. |
aspartate β-hydroxylase (asph) is silent in normal adult tissues only to re-emerge during oncogenesis where its function is required for generation and maintenance of malignant phenotypes. |
2020-04-15 |
2023-08-13 |
Not clear |
| Sascha Kopp, Marcus Krüger, Stefan Feldmann, Hergen Oltmann, Andreas Schütte, Burkhard Schmitz, Johann Bauer, Herbert Schulz, Kathrin Saar, Norbert Huebner, Markus Wehland, Mohamed Zakaria Nassef, Daniela Melnik, Stefan Meltendorf, Manfred Infanger, Daniela Grim. Thyroid cancer cells in space during the TEXUS-53 sounding rocket mission - The THYROID Project. Scientific reports. vol 8. issue 1. 2019-10-11. PMID:29985426. |
egf upregulates aspartate beta-hydroxylase (asph) which is influencing casp3. |
2019-10-11 |
2023-08-13 |
human |
| Chiung-Kuei Huang, Yoshifumi Iwagami, Jing Zou, Sarah Casulli, Shaolei Lu, Katsuya Nagaoka, Chengcheng Ji, Kousuke Ogawa, Kevin Y Cao, Jin-Song Gao, Rolf I Carlson, Jack R Wand. Aspartate beta-hydroxylase promotes cholangiocarcinoma progression by modulating RB1 phosphorylation. Cancer letters. vol 429. 2019-08-05. PMID:29733964. |
we investigated if the 2-og dependent dioxygenase, aspartate beta-hydroxylase (asph) was important in tumor development and growth. |
2019-08-05 |
2023-08-13 |
human |
| Guofang Hou, Boran Xu, Yanghui Bi, Chuanlin Wu, Beibei Ru, Bei Sun, Xuewei Ba. Recent advances in research on aspartate β-hydroxylase (ASPH) in pancreatic cancer: A brief update. Bosnian journal of basic medical sciences. vol 18. issue 4. 2019-02-21. PMID:30179586. |
recent advances in research on aspartate β-hydroxylase (asph) in pancreatic cancer: a brief update. |
2019-02-21 |
2023-08-13 |
Not clear |
| Guofang Hou, Boran Xu, Yanghui Bi, Chuanlin Wu, Beibei Ru, Bei Sun, Xuewei Ba. Recent advances in research on aspartate β-hydroxylase (ASPH) in pancreatic cancer: A brief update. Bosnian journal of basic medical sciences. vol 18. issue 4. 2019-02-21. PMID:30179586. |
aspartate β-hydroxylase (asph) is a type ii transmembrane protein and the member of α-ketoglutarate-dependent dioxygenase family, found to be overexpressed in different cancer types, including pc. |
2019-02-21 |
2023-08-13 |
Not clear |
| Yoshifumi Iwagami, Chiung-Kuei Huang, Mark J Olsen, John-Michael Thomas, Grace Jang, Miran Kim, Qiushi Lin, Rolf I Carlson, Carl E Wagner, Xiaoqun Dong, Jack R Wand. Aspartate β-hydroxylase modulates cellular senescence through glycogen synthase kinase 3β in hepatocellular carcinoma. Hepatology (Baltimore, Md.). vol 63. issue 4. 2016-08-02. PMID:26683595. |
aspartate β-hydroxylase (asph) is an enzyme overexpressed in human hepatocellular carcinoma (hcc) tumors that participates in the malignant transformation process. |
2016-08-02 |
2023-08-13 |
mouse |
| Chiung-Kuei Huang, Yoshifumi Iwagami, Arihiro Aihara, Waihong Chung, Suzanne de la Monte, John-Michael Thomas, Mark Olsen, Rolf Carlson, Tunan Yu, Xiaoqun Dong, Jack Wand. Anti-Tumor Effects of Second Generation β-Hydroxylase Inhibitors on Cholangiocarcinoma Development and Progression. PloS one. vol 11. issue 3. 2016-08-01. PMID:26954680. |
aspartate β-hydroxylase (asph) is a transmembrane protein and catalyzes the hydroxylation of aspartyl and asparaginyl residues in calcium binding epidermal growth factor (cbegf)-like domains of various proteins, including notch receptors and ligands. |
2016-08-01 |
2023-08-13 |
human |
| Xiaoqun Dong, Qiushi Lin, Arihiro Aihara, Yu Li, Chiung-Kuei Huang, Waihong Chung, Qi Tang, Xuesong Chen, Rolf Carlson, Christina Nadolny, Gregory Gabriel, Mark Olsen, Jack R Wand. Aspartate β-Hydroxylase expression promotes a malignant pancreatic cellular phenotype. Oncotarget. vol 6. issue 2. 2015-11-27. PMID:25483102. |
aspartate β-hydroxylase (asph), a cell surface protein that catalyzes the hydroxylation of epidermal growth factor (egf)-like repeats in notch receptors and ligands, is highly overexpressed in pc. |
2015-11-27 |
2023-08-13 |
Not clear |
| P Whiteman, C Marks, E Frees. The sodium effect of Bacillus subtilis growth on aspartate. Journal of general microbiology. vol 119. issue 2. 1981-07-09. PMID:6785382. |
asph mutants of bacillus subtilis have a constitutive aspartase activity and grow well on aspartate as sole carbon source. |
1981-07-09 |
2023-08-12 |
Not clear |
| P Whiteman, C Marks, E Frees. The sodium effect of Bacillus subtilis growth on aspartate. Journal of general microbiology. vol 119. issue 2. 1981-07-09. PMID:6785382. |
asph aspt mutants, which are deficient in high affinity aspartate transport as a result of the aspt mutation, grow as well as asph mutants in medium containing high concentrations of aspartate and na+. |
1981-07-09 |
2023-08-12 |
Not clear |
| T Iijima, M D Diesterhaft, E Frees. Sodium effect of growth on aspartate and genetic analysis of a Bacillus subtilis mutant with high aspartase activity. Journal of bacteriology. vol 129. issue 3. 1977-05-12. PMID:403177. |
although sodium ions do not affect growth on glucose or l-malate, they specifically stimulate growth on aspartate in both the parent and the asph mutant strains. |
1977-05-12 |
2023-08-11 |
Not clear |
| T Iijima, M D Diesterhaft, E Frees. Sodium effect of growth on aspartate and genetic analysis of a Bacillus subtilis mutant with high aspartase activity. Journal of bacteriology. vol 129. issue 3. 1977-05-12. PMID:403177. |
we isolated a mutant (asph) that grows rapidly on aspartate because it produces aspartase constitutively. |
1977-05-12 |
2023-08-11 |
Not clear |
| T Iijima, M D Diesterhaft, E Frees. Sodium effect of growth on aspartate and genetic analysis of a Bacillus subtilis mutant with high aspartase activity. Journal of bacteriology. vol 129. issue 3. 1977-05-12. PMID:403177. |
the ease of purification from the asph strain and the stability of aspartase suggest that the b. subtilis enzyme is particularly useful for aspartate determinations. |
1977-05-12 |
2023-08-11 |
Not clear |