| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shah Fahad Husami, Tavleen Kaur, Love Gupta, Garima Rastogi, Lakhvinder Singh, Pooja Meena, Indu Sharma, Hemender Singh, Varun Sharm. Corporate genome screening India (CoGsI) identified genetic variants association with T2D in young Indian professionals. Scientific reports. vol 15. issue 1. 2025-01-03. PMID:39747296. |
out of 42, three missense variants (rs1402467, rs6050, and rs713598) in sulfotransferase family 1 c member 4 (sult1c4), fibrinogen alpha chain (fga), and taste 2 receptor member 38 (tas2r38) and two untranslated region (utr) variants (rs1063320 and rs6296) in major histocompatibility complex, class i, g (hla-g) and 5-hydroxytryptamine receptor 1b (htr1b) were associated with the t2d risk. |
2025-01-03 |
2025-01-05 |
Not clear |
| Paule Valery Joseph, Malak Abbas, Gabriel Goodney, Ana Diallo, Amadou Gay. Genomic Study of Taste Perception Genes in African Americans Reveals SNPs Linked to Alzheimer's Disease. bioRxiv : the preprint server for biology. 2024-10-07. PMID:39372803. |
taste perception involves neurotransmitter signaling, including serotonin, glutamate, and dopamine. |
2024-10-07 |
2024-10-09 |
Not clear |
| Paule Valery Joseph, Malak Abbas, Gabriel Goodney, Ana Diallo, Amadou Gay. Genomic study of taste perception genes in African Americans reveals SNPs linked to Alzheimer's disease. Scientific reports. vol 14. issue 1. 2024-09-16. PMID:39284855. |
taste perception involves neurotransmitter signaling, including serotonin, glutamate, and dopamine. |
2024-09-16 |
2024-09-19 |
human |
| Takanori Ikenaga, Tastufumi Nakamura, Tatsushi Tajiri, Minaki Tsuji, Dai-Ichiro Kato, Toshinao Ineno, Yasuhisa Kobayashi, Naoaki Tsutsui, Sadao Kiyohar. Diversity and evolution of serotonergic cells in taste buds of elasmobranchs and ancestral actinopterygian fish. Cell and tissue research. 2023-10-18. PMID:37851111. |
while serotonin immunoreactivity was observed only in the basal cells in the taste buds of the ancestral actinopterygian fish, some elongated cells were also serotonin-ir in addition to the basal cells in the stingray taste buds. |
2023-10-18 |
2023-11-08 |
Not clear |
| Takanori Ikenaga, Tastufumi Nakamura, Tatsushi Tajiri, Minaki Tsuji, Dai-Ichiro Kato, Toshinao Ineno, Yasuhisa Kobayashi, Naoaki Tsutsui, Sadao Kiyohar. Diversity and evolution of serotonergic cells in taste buds of elasmobranchs and ancestral actinopterygian fish. Cell and tissue research. 2023-10-18. PMID:37851111. |
a subset of gustatory cells are serotonin immunoreactive (ir) in the mammalian taste bud. |
2023-10-18 |
2023-11-08 |
Not clear |
| Takanori Ikenaga, Tastufumi Nakamura, Tatsushi Tajiri, Minaki Tsuji, Dai-Ichiro Kato, Toshinao Ineno, Yasuhisa Kobayashi, Naoaki Tsutsui, Sadao Kiyohar. Diversity and evolution of serotonergic cells in taste buds of elasmobranchs and ancestral actinopterygian fish. Cell and tissue research. 2023-10-18. PMID:37851111. |
mrna of tryptophan hydroxylase 1 (tph1), a rate-limiting enzyme of the serotonin synthesis, is expressed in both the elongated and basal cells of stingray taste buds, indicating that these cells synthesize the serotonin by themselves. |
2023-10-18 |
2023-11-08 |
Not clear |
| Satomi Kobayashi, Mie Kajiwara, Yilong Cui, Takeo Sako, Tetsuya Sasabe, Emi Hayashinaka, Yasuhiro Wada, Masayuki Kobayash. Activation of multiple neuromodulatory systems in alert rats acquiring conditioned taste aversion revealed by positron emission tomography. Brain research. 2023-10-07. PMID:37805008. |
conditioned taste aversion (cta) is an essential ability for animals to consume food safely and is regulated by neuromodulatory systems including the dopamine, noradrenaline, serotonin, and acetylcholine systems. |
2023-10-07 |
2023-10-15 |
rat |
| Hayley N Manke, Kenner C Rice, Anthony L Rile. Effects of Methylone Pre-Exposure on Fluoxetine-Induced Conditioned Taste Avoidance in Male and Female Sprague-Dawley Rats. Brain sciences. vol 13. issue 4. 2023-05-16. PMID:37190550. |
to examine the possible role of serotonin (5-ht) in methylone's aversive effects, the present study assessed the effects of methylone pre-exposure on taste avoidance induced by the 5-ht reuptake inhibitor fluoxetine. |
2023-05-16 |
2023-08-14 |
rat |
| Ashwini Biradar, C B Ganes. Serotonin-immunoreactivity in the brain of the cichlid fish Oreochromis mossambicus. Anatomical record (Hoboken, N.J. : 2007). 2023-03-20. PMID:36938774. |
while the presence of 5-ht-ir cells and fibers in gustatory centers suggests a role for serotonin in the processing of gustatory signals, distinctive pattern of 5-ht immunoreactivity was seen in the telencephalon, pretectal areas, mesencephalic, and rhombencephalic regions, suggesting a cichlid fish specific organization of the serotonergic system. |
2023-03-20 |
2023-08-14 |
Not clear |
| Niklas Reich, Christian Hölsche. Beyond Appetite: Acylated Ghrelin As A Learning, Memory and Fear Behavior-modulating Hormone. Neuroscience and biobehavioral reviews. 2022-11-11. PMID:36368526. |
as such, in this review, we i) evaluate what specific stages and forms of memory, as well as which respective brain areas are affected by acylated ghrelin, ii) illustrate the plasticity-associated signaling pathways of ag in the hippocampus, also involving memory resolution-enhancing neurogenesis, iii) elucidate how the peptide modulates neurotransmitter systems (glutamate, γ-aminobutyric acid, dopamine, serotonin), iv) clarify the role of ag in conditioned taste aversion, novelty learning and the formation of spatial, recognition, auditory fear, contextual fear and passive avoidance memories in the hippocampus and amygdala as well as v) solve the mystery behind ag, its impact on the 5-ht system, the recently established link to post-traumatic stress disorder and the either fear-suppressing or fear-potentiating effects under neutral and acutely stressed conditions or chronic stress, respectively. |
2022-11-11 |
2023-08-14 |
Not clear |
| Verenice Ascencio Gutierrez, Audrey A Carrillo, Gretha J Boersma, Kellie L K Tamashiro, Timothy H Moran, Sergio D Iñiguez, Yada Treesukoso. Effect of early-life stress or fluoxetine exposure on later-life conditioned taste aversion learning in Sprague-Dawley rats. Neuroscience letters. 2022-08-05. PMID:35931277. |
to expand on this line of work, we evaluated how juvenile exposure to chronic variable stress (cvs) or the selective serotonin reuptake inhibitor fluoxetine (flx) influences conditioned taste aversion (cta) learning in adulthood. |
2022-08-05 |
2023-08-14 |
rat |
| Ling Bai, Nilla Sivakumar, Shenliang Yu, Sheyda Mesgarzadeh, Tom Ding, Truong Ly, Timothy V Corpuz, James C R Grove, Brooke C Jarvie, Zachary A Knigh. Enteroendocrine cell types that drive food reward and aversion. eLife. vol 11. 2022-08-01. PMID:35913117. |
conditioned flavor preference is driven by release of cholecystokinin whereas conditioned taste aversion is mediated by serotonin and substance p. these positive and negative valence signals are transmitted by vagal and spinal afferents, respectively. |
2022-08-01 |
2023-08-14 |
mouse |
| Aleksandr P Cherkashin, Olga A Rogachevskaja, Natalia V Kabanova, Polina D Kotova, Marina F Bystrova, Stanislav S Kolesniko. Taste Cells of the Type III Employ CASR to Maintain Steady Serotonin Exocytosis at Variable Ca Cells. vol 11. issue 8. 2022-04-23. PMID:35456048. |
taste cells of the type iii employ casr to maintain steady serotonin exocytosis at variable ca type iii taste cells are the only taste bud cells which express voltage-gated (vg) ca |
2022-04-23 |
2023-08-13 |
Not clear |
| Zepeng Yao, Kristin Scot. Serotonergic neurons translate taste detection into internal nutrient regulation. Neuron. 2022-01-20. PMID:35051377. |
here, we identify serotonergic (5-ht) neurons as critical mediators that transform gustatory detection by sensory neurons into the activation of insulin-producing cells and enteric neurons in drosophila. |
2022-01-20 |
2023-08-13 |
drosophila_melanogaster |
| Zepeng Yao, Kristin Scot. Serotonergic neurons translate taste detection into internal nutrient regulation. Neuron. 2022-01-20. PMID:35051377. |
a second class of 5-ht neurons responds to gustatory detection of bitter compounds and activates enteric neurons to promote gastric motility, likely to stimulate digestion and increase circulating nutrients upon food rejection. |
2022-01-20 |
2023-08-13 |
drosophila_melanogaster |
| Zepeng Yao, Kristin Scot. Serotonergic neurons translate taste detection into internal nutrient regulation. Neuron. 2022-01-20. PMID:35051377. |
these studies demonstrate that 5-ht neurons relay acute gustatory detection to divergent pathways for longer-term stabilization of circulating nutrients. |
2022-01-20 |
2023-08-13 |
drosophila_melanogaster |
| Zepeng Yao, Kristin Scot. Serotonergic neurons translate taste detection into internal nutrient regulation. Neuron. 2022-01-20. PMID:35051377. |
one class of 5-ht neurons responds to gustatory detection of sugars, excites insulin-producing cells, and limits consumption, suggesting that they anticipate increased nutrient levels and prevent overconsumption. |
2022-01-20 |
2023-08-13 |
drosophila_melanogaster |
| Stephen D Rope. Chemical and electrical synaptic interactions among taste bud cells. Current opinion in physiology. vol 20. 2021-09-16. PMID:33521414. |
the identification of serotonin and atp as taste neurotransmitters focused attention onto chemical synaptic interactions between taste cells and research on electrical coupling faded. |
2021-09-16 |
2023-08-13 |
Not clear |
| Sharon A Smith, Paula D Trotter, Francis P McGlone, Susannah C Walke. Effects of Acute Tryptophan Depletion on Human Taste Perception. Chemical senses. vol 46. 2021-08-26. PMID:33277648. |
however, the specific effects of central serotonin function on taste processing have not been widely investigated. |
2021-08-26 |
2023-08-13 |
human |
| Sharon A Smith, Paula D Trotter, Francis P McGlone, Susannah C Walke. Effects of Acute Tryptophan Depletion on Human Taste Perception. Chemical senses. vol 46. 2021-08-26. PMID:33277648. |
these findings show manipulation of central serotonin levels can modulate taste perception and are consistent with previous reports that depletion of central serotonin levels enhances neural and behavioral responsiveness to aversive signals. |
2021-08-26 |
2023-08-13 |
human |