| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jonathan D Lautz, Emily A Brown, Alison A Williams VanSchoiack, Stephen E P Smit. Synaptic activity induces input-specific rearrangements in a targeted synaptic protein interaction network. Journal of neurochemistry. vol 146. issue 5. 2019-06-26. PMID:29804286. |
our data support a model of synaptic plasticity in which synaptic stimulation elicits dissociation of pre-existing multiprotein complexes, opening binding slots in scaffold proteins and allowing for the recruitment of additional glutamatergic receptors. |
2019-06-26 |
2023-08-13 |
Not clear |
| Alexey Ostroumov, John A Dan. Convergent Neuronal Plasticity and Metaplasticity Mechanisms of Stress, Nicotine, and Alcohol. Annual review of pharmacology and toxicology. vol 58. 2019-06-21. PMID:28977763. |
we describe several forms of alcohol-induced plasticity, including classic hebbian plasticity at glutamatergic synapses, and we highlight less appreciated forms, such as non-hebbian and gabaergic synaptic plasticity. |
2019-06-21 |
2023-08-13 |
Not clear |
| Dorit Ben-Shachar, Hila M En. Mitochondrial Targeted Therapies: Where Do We Stand in Mental Disorders? Biological psychiatry. vol 83. issue 9. 2019-06-18. PMID:28965983. |
the neurobiology of psychiatric disorders is still unclear, although changes in multiple neuronal systems, specifically the dopaminergic, glutamatergic, and gamma-aminobutyric acidergic systems as well as abnormalities in synaptic plasticity and neural connectivity, are currently suggested to underlie their pathophysiology. |
2019-06-18 |
2023-08-13 |
Not clear |
| Carina Volk, Valeria Jaramillo, Renato Merki, Ruth O'Gorman Tuura, Reto Hube. Diurnal changes in glutamate + glutamine levels of healthy young adults assessed by proton magnetic resonance spectroscopy. Human brain mapping. vol 39. issue 10. 2019-06-03. PMID:29885049. |
the glutamatergic α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptor is involved in synaptic plasticity processes, and animal studies have demonstrated altered expression across the sleep wake cycle. |
2019-06-03 |
2023-08-13 |
Not clear |
| Mari Inohana, Ayumi Eguchi, Misato Nakamura, Rei Nagahara, Nobuhiko Onda, Kota Nakajima, Yukie Saegusa, Toshinori Yoshida, Makoto Shibutan. Developmental Exposure to Aluminum Chloride Irreversibly Affects Postnatal Hippocampal Neurogenesis Involving Multiple Functions in Mice. Toxicological sciences : an official journal of the Society of Toxicology. vol 164. issue 1. 2019-05-24. PMID:29635646. |
transcript expression changes on cholinergic and glutamatergic signals and synaptic plasticity suggested contribution to disruptive neurogenesis. |
2019-05-24 |
2023-08-13 |
mouse |
| Lejla Colic, Conor McDonnell, Meng Li, Marie Woelfer, Thomas Liebe, Moritz Kretzschmar, Oliver Speck, Björn H Schott, Massimiliano Bianchi, Martin Walte. Neuronal glutamatergic changes and peripheral markers of cytoskeleton dynamics change synchronically 24 h after sub-anaesthetic dose of ketamine in healthy subjects. Behavioural brain research. vol 359. 2019-04-19. PMID:30342064. |
ketamine acts as a rapid-acting antidepressant by restoring glutamatergic deficits and activating synaptic plasticity processes, with peak activity 24 h after infusion. |
2019-04-19 |
2023-08-13 |
human |
| Ji-Yuan Zhao, Xing-Lian Duan, Li Yang, Jiang-Ping Liu, Yong-Tao He, Zhen Guo, Xiao-Dong Hu, Zhan-Wei Su. Activity-dependent Synaptic Recruitment of Neuroligin 1 in Spinal Dorsal Horn Contributed to Inflammatory Pain. Neuroscience. vol 388. 2019-03-29. PMID:30049666. |
neuroligin 1 (nlgn1), a cell adhesion molecule present at excitatory glutamatergic synapses, has been shown to be critical for synaptic specialization and n-methyl-d-aspartate (nmda)-subtype glutamate receptor-dependent synaptic plasticity. |
2019-03-29 |
2023-08-13 |
mouse |
| Lejla Colic, Marie Woelfer, Merima Colic, Anna Linda Leutritz, Thomas Liebe, Luisa Fensky, Zumrut Duygu Sen, Meng Li, Juliane Hoffmann, Moritz A Kretzschmar, Berend Isermann, Martin Walte. Delayed increase of thrombocyte levels after a single sub-anesthetic dose of ketamine - A randomized trial. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 28. issue 6. 2019-03-22. PMID:29699723. |
unlike traditional drugs, it yields immediate effects, most likely via increased glutamatergic transmission and synaptic plasticity. |
2019-03-22 |
2023-08-13 |
human |
| Meng-He Zhou, Fang-Fang Sun, Chang Xu, Hui-Bin Chen, Hui Qiao, Xiang Cai, Xin-Ming Ma, Shu-Cheng A. Modulation of Kalirin-7 expression by hippocampal CA1 5-HT Behavioural brain research. vol 356. 2019-03-22. PMID:29949735. |
however, the role and its underlying mechanism of 5-ht1br activation-mediated glutamatergic synaptic plasticity in spatial memory are not fully understood. |
2019-03-22 |
2023-08-13 |
rat |
| Dainan Zhang, Meng Xiao, Long Wang, Wang Ji. Blood-Based Glutamate Scavengers Reverse Traumatic Brain Injury-Induced Synaptic Plasticity Disruption by Decreasing Glutamate Level in Hippocampus Interstitial Fluid, but Not Cerebral Spinal Fluid, In Vivo. Neurotoxicity research. vol 35. issue 2. 2019-03-11. PMID:30255425. |
prior to the presence of behavior change, synaptic plasticity is rapidly and potently disrupted by tbi, which is believed to be relevant to inappropriately increased extracellular glutamate concentration and glutamatergic receptor activation. |
2019-03-11 |
2023-08-13 |
rat |
| Lenka Mikasova, Hui Xiong, Amber Kerkhofs, Delphine Bouchet, Harm J Krugers, Laurent Gro. Stress hormone rapidly tunes synaptic NMDA receptor through membrane dynamics and mineralocorticoid signalling. Scientific reports. vol 7. issue 1. 2019-03-05. PMID:28808323. |
stress hormones, such as corticosteroids, modulate the transmission of hippocampal glutamatergic synapses and nmda receptor (nmdar)-dependent synaptic plasticity, favouring salient behavioural responses to the environment. |
2019-03-05 |
2023-08-13 |
Not clear |
| Maria Papathanou, Meaghan Creed, Matthijs C Dorst, Zisis Bimpisidis, Sylvie Dumas, Hanna Pettersson, Camilla Bellone, Gilad Silberberg, Christian Lüscher, Åsa Wallén-Mackenzi. Targeting VGLUT2 in Mature Dopamine Neurons Decreases Mesoaccumbal Glutamatergic Transmission and Identifies a Role for Glutamate Co-release in Synaptic Plasticity by Increasing Baseline AMPA/NMDA Ratio. Frontiers in neural circuits. vol 12. 2019-03-04. PMID:30210305. |
targeting vglut2 in mature dopamine neurons decreases mesoaccumbal glutamatergic transmission and identifies a role for glutamate co-release in synaptic plasticity by increasing baseline ampa/nmda ratio. |
2019-03-04 |
2023-08-13 |
Not clear |
| Gaohua Liu, Dayun Feng, Jian Wang, Haifeng Zhang, Zhengwu Peng, Min Cai, Jing Yang, Ruiguo Zhang, Huaning Wang, Shengxi Wu, Qingrong Ta. rTMS Ameliorates PTSD Symptoms in Rats by Enhancing Glutamate Transmission and Synaptic Plasticity in the ACC via the PTEN/Akt Signalling Pathway. Molecular neurobiology. vol 55. issue 5. 2019-02-26. PMID:28550530. |
analysis by western blot, double immunofluorescence, golgi staining and behavioural tests demonstrated that the effects of rtms on pten/akt activation, glutamatergic receptor expression, neuronal synaptic plasticity and ptsd-related behaviours induced by sps treatment were enhanced by pten inhibition and blocked by akt inhibition in the acc. |
2019-02-26 |
2023-08-13 |
rat |
| Chunyue Huo, Xu Liu, Jialu Zhao, Tian Zhao, Huiling Huang, Haihong Y. Abnormalities in behaviour, histology and prefrontal cortical gene expression profiles relevant to schizophrenia in embryonic day 17 MAM-Exposed C57BL/6 mice. Neuropharmacology. vol 140. 2019-02-20. PMID:30056124. |
mam-exposed female mice may be used to study gene expression changes, inhibitory neural circuit dysfunction and glutamatergic synaptic plasticity deficits with a possible relation to those in the brains of scz patients. |
2019-02-20 |
2023-08-13 |
mouse |
| Goce Taleski, Estelle Sonta. Protein phosphatase 2A and tau: an orchestrated 'Pas de Deux'. FEBS letters. vol 592. issue 7. 2019-02-05. PMID:29121398. |
furthermore, it contributes to glutamatergic regulation and synaptic plasticity. |
2019-02-05 |
2023-08-13 |
Not clear |
| Juan Cheng, Xu Huang, Yue Liang, Tian Xue, Liecheng Wang, Jin Ba. Plasticity of Light-induced Concurrent Glutamatergic and GABAergic Quantal Events in the Suprachiasmatic Nucleus. Journal of biological rhythms. vol 33. issue 1. 2019-01-30. PMID:29432701. |
this work provides evidence for light-dependent synaptic plasticity at glutamatergic and gabaergic input synapses of ventral scn neurons. |
2019-01-30 |
2023-08-13 |
Not clear |
| Ada Ledonne, Dalila Mango, Emanuele Claudio Latagliata, Giulia Chiacchierini, Annalisa Nobili, Robert Nisticò, Marcello D'Amelio, Stefano Puglisi-Allegra, Nicola Biagio Mercur. Neuregulin 1/ErbB signalling modulates hippocampal mGluRI-dependent LTD and object recognition memory. Pharmacological research. vol 130. 2019-01-18. PMID:29427771. |
group 1 metabotropic glutamate receptors (mgluri)-dependent mechanisms are also altered in animal models of neuropsychiatric diseases, especially mgluri-induced glutamatergic long-term depression (mgluri-ltd), a form of synaptic plasticity critically involved in learning and memory. |
2019-01-18 |
2023-08-13 |
mouse |
| C M Mazzone, D Pati, M Michaelides, J DiBerto, J H Fox, G Tipton, C Anderson, K Duffy, J M McKlveen, J A Hardaway, S T Magness, W A Falls, S E Hammack, Z A McElligott, Y L Hurd, T L Kas. Acute engagement of G Molecular psychiatry. vol 23. issue 1. 2018-12-17. PMID:27956747. |
further, we identified that activation of hm3dq receptors in bnst vgat neurons can induce a long-term depression-like state of glutamatergic synaptic transmission, indicating dreadd-induced changes in synaptic plasticity. |
2018-12-17 |
2023-08-13 |
Not clear |
| Nam-Kyung Yu, Heesoo Uhm, Jaehoon Shim, Jun-Hyeok Choi, Sangsu Bae, Todd Charlton Sacktor, Sungchul Hohng, Bong-Kiun Kaan. Increased PKMζ activity impedes lateral movement of GluA2-containing AMPA receptors. Molecular brain. vol 10. issue 1. 2018-10-16. PMID:29202853. |
the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptor (ampar) mediates most of the fast glutamatergic synaptic transmission in the brain and is known to be critical for the expression of synaptic plasticity and memory. |
2018-10-16 |
2023-08-13 |
Not clear |
| Wallace C Duncan, Elizabeth Slonena, Nadia S Hejazi, Nancy Brutsche, Kevin C Yu, Lawrence Park, Elizabeth D Ballard, Carlos A Zarat. Motor-Activity Markers of Circadian Timekeeping Are Related to Ketamine's Rapid Antidepressant Properties. Biological psychiatry. vol 82. issue 5. 2018-09-04. PMID:28457485. |
the rapid clinical antidepressant effects of the glutamatergic modulator ketamine may be due to its ability to restore synaptic plasticity and related effects on sleep-wake and circadian systems. |
2018-09-04 |
2023-08-13 |
Not clear |