| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Miriam Melis, Gianfranca Carta, Marco Pistis, Sebastiano Bann. Physiological role of peroxisome proliferator-activated receptors type α on dopamine systems. CNS & neurological disorders drug targets. vol 12. issue 1. 2013-12-23. PMID:23394525. |
the discovery that n-acylethanolamines, such as oleoylethanolamide (oea) and palmitoylethanolamide (pea), acting as endogenous ligands of alpha-type peroxisome proliferator-activated receptors (pparα), block nicotine-induced excitation of dopamine neurons revealed their role as important endogenous negative modulators of nicotinic receptors containing β2 subunits (denoted β2*-nachrs) on dopamine neurons, which are key to the brain reward system. |
2013-12-23 |
2023-08-12 |
Not clear |
| F Saint-Preux, L R Bores, I Tulloch, B Ladenheim, R Kim, P K Thanos, N D Volkow, J L Cade. Chronic co-administration of nicotine and methamphetamine causes differential expression of immediate early genes in the dorsal striatum and nucleus accumbens of rats. Neuroscience. vol 243. 2013-12-17. PMID:23562942. |
nicotine and methamphetamine (meth) cause addiction by triggering neuroplastic changes in brain reward pathways though they each engage distinct molecular targets (nicotine receptors and dopamine transporters respectively). |
2013-12-17 |
2023-08-12 |
rat |
| Guillermo Lahera, Namdev Freund, Jerónimo Sáiz-Rui. Salience and dysregulation of the dopaminergic system. Revista de psiquiatria y salud mental. vol 6. issue 1. 2013-12-13. PMID:23084802. |
the aberrant salience occurs when the dysregulation of dopamine transmission produces a mistaken interpretation of neutral or irrelevant stimuli as a source of reward or punishment. |
2013-12-13 |
2023-08-12 |
Not clear |
| Y Yan, H Kong, E J Wu, A H Newman, M X. Dopamine D3 receptors regulate reconsolidation of cocaine memory. Neuroscience. vol 241. 2013-12-12. PMID:23506736. |
dopamine (da) mediates the acquisition of reward memory and drugs of abuse can pathologically change related neuronal circuits in the mesolimbic da system. |
2013-12-12 |
2023-08-12 |
mouse |
| Jennifer S Mascaro, Patrick D Hackett, James K Rillin. Testicular volume is inversely correlated with nurturing-related brain activity in human fathers. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 39. 2013-12-11. PMID:24019499. |
in response to viewing pictures of one's own child, activity in the ventral tegmental area--a key component of the mesolimbic dopamine reward and motivation system--predicted paternal caregiving and was negatively related to testes volume. |
2013-12-11 |
2023-08-12 |
human |
| Edward H Nieh, Sung-Yon Kim, Praneeth Namburi, Kay M Ty. Optogenetic dissection of neural circuits underlying emotional valence and motivated behaviors. Brain research. vol 1511. 2013-12-09. PMID:23142759. |
within the mesolimbic dopamine system, optogenetics has helped separate subsets of dopamine neurons with distinct functions for reward, aversion and salience processing, elucidated gaba neuronal effects on behavior, and characterized connectivity with forebrain and cortical structures. |
2013-12-09 |
2023-08-12 |
Not clear |
| Colin G Deyoun. The neuromodulator of exploration: A unifying theory of the role of dopamine in personality. Frontiers in human neuroscience. vol 7. 2013-12-02. PMID:24294198. |
the neuromodulator dopamine is centrally involved in reward, approach behavior, exploration, and various aspects of cognition. |
2013-12-02 |
2023-08-12 |
Not clear |
| Colin G Deyoun. The neuromodulator of exploration: A unifying theory of the role of dopamine in personality. Frontiers in human neuroscience. vol 7. 2013-12-02. PMID:24294198. |
the general function of dopamine is to promote exploration, by facilitating engagement with cues of specific reward (value) and cues of the reward value of information (salience). |
2013-12-02 |
2023-08-12 |
Not clear |
| Jennifer A Mohawk, Pinar Pezuk, Michael Menake. Methamphetamine and dopamine receptor D1 regulate entrainment of murine circadian oscillators. PloS one. vol 8. issue 4. 2013-11-26. PMID:23626822. |
it has been suggested that reward pathways, and dopamine signaling in particular, may underlie the effects of ma on the circadian system. |
2013-11-26 |
2023-08-12 |
mouse |
| Jakob Linne. The Iowa Gambling Task and the three fallacies of dopamine in gambling disorder. Frontiers in psychology. vol 4. 2013-11-18. PMID:24115941. |
studies of reward prediction and reward uncertainty show a sustained dopamine response toward stimuli with maximum uncertainty, which may explain the continued dopamine release and gambling despite losses in gambling disorder. |
2013-11-18 |
2023-08-12 |
Not clear |
| M Cardoso Fernandes Toffolo, C Aparecida Marliére, S Nascimento de Freitas, A Silva de Aguiar Neme. Increasing leptin level in abstaining alcohol-dependent women. Nutricion hospitalaria. vol 27. issue 3. 2013-11-06. PMID:23114944. |
leptin, hormone secreted by the fat tissue, changes the signaling of dopamine in the nucleus accumbens, which directly affects the sensitivity of reward and modulation of abstinence. |
2013-11-06 |
2023-08-12 |
Not clear |
| Sari Maril, Sharon Hassin-Baer, Oren S Cohen, Rachel Tome. Effects of asymmetric dopamine depletion on sensitivity to rewarding and aversive stimuli in Parkinson's disease. Neuropsychologia. vol 51. issue 5. 2013-11-05. PMID:23422331. |
as dopamine replacement therapy (drt) has shown different effects on reward and punishment processing, all participants were assessed in both off- and on-medication states. |
2013-11-05 |
2023-08-12 |
human |
| Yukie Kawahara, Fumi Kaneko, Makiko Yamada, Yuki Kishikawa, Hiroshi Kawahara, Akinori Nish. Food reward-sensitive interaction of ghrelin and opioid receptor pathways in mesolimbic dopamine system. Neuropharmacology. vol 67. 2013-11-04. PMID:23220294. |
thus, natural food reward and systemic ghrelin activate mu and kappa opioid receptor pathways in the vta, respectively, resulting in opposite influences on dopamine release in the nac. |
2013-11-04 |
2023-08-12 |
rat |
| Robert Adam, Alexander Leff, Nihal Sinha, Christopher Turner, Paul Bays, Bogdan Draganski, Masud Husai. Dopamine reverses reward insensitivity in apathy following globus pallidus lesions. Cortex; a journal devoted to the study of the nervous system and behavior. vol 49. issue 5. 2013-10-30. PMID:22721958. |
dopamine reverses reward insensitivity in apathy following globus pallidus lesions. |
2013-10-30 |
2023-08-12 |
Not clear |
| Toni-Kim Clarke, Paul J Bloch, Lisa M Ambrose-Lanci, Thomas N Ferraro, Wade H Berrettini, Kyle M Kampman, Charles A Dackis, Helen M Pettinati, Charles P O'Brien, David W Oslin, Falk W Lohof. Further evidence for association of polymorphisms in the CNR1 gene with cocaine addiction: confirmation in an independent sample and meta-analysis. Addiction biology. vol 18. issue 4. 2013-10-29. PMID:21790903. |
as endocannabinoid signaling and dopamine neurotransmission have been shown to be involved in drug reward, genes related to these systems are plausible candidates for susceptibility to cd. |
2013-10-29 |
2023-08-12 |
Not clear |
| Anne-Marie Bédard, Jérôme Maheux, Daniel Lévesque, Anne-Noël Samah. Prior haloperidol, but not olanzapine, exposure augments the pursuit of reward cues: implications for substance abuse in schizophrenia. Schizophrenia bulletin. vol 39. issue 3. 2013-10-28. PMID:22927669. |
dopamine supersensitivity can enhance the incentive motivational properties of reward cues, and reward cues contribute to the maintenance and severity of drug addiction. |
2013-10-28 |
2023-08-12 |
rat |
| Anne-Marie Bédard, Jérôme Maheux, Daniel Lévesque, Anne-Noël Samah. Prior haloperidol, but not olanzapine, exposure augments the pursuit of reward cues: implications for substance abuse in schizophrenia. Schizophrenia bulletin. vol 39. issue 3. 2013-10-28. PMID:22927669. |
we have shown previously that rats withdrawn from continuous haloperidol (hal) treatment (via subcutaneous minipump) develop dopamine supersensitivity and pursue reward cues more vigorously than hal-naive rats following an amphetamine (amph) challenge. |
2013-10-28 |
2023-08-12 |
rat |
| Susana Peciña, Kent C Berridg. Dopamine or opioid stimulation of nucleus accumbens similarly amplify cue-triggered 'wanting' for reward: entire core and medial shell mapped as substrates for PIT enhancement. The European journal of neuroscience. vol 37. issue 9. 2013-10-28. PMID:23495790. |
dopamine or opioid stimulation of nucleus accumbens similarly amplify cue-triggered 'wanting' for reward: entire core and medial shell mapped as substrates for pit enhancement. |
2013-10-28 |
2023-08-12 |
Not clear |
| Susana Peciña, Kent C Berridg. Dopamine or opioid stimulation of nucleus accumbens similarly amplify cue-triggered 'wanting' for reward: entire core and medial shell mapped as substrates for PIT enhancement. The European journal of neuroscience. vol 37. issue 9. 2013-10-28. PMID:23495790. |
we tested the ability of dopamine stimulation (by amphetamine microinjection) vs. mu opioid stimulation [by d-ala, nme-phe, glyol-enkephalin (damgo) microinjection] of either the core or shell of the nac to amplify cue-triggered levels of motivation to pursue sucrose reward, measured with a pavlovian-instrumental transfer (pit) procedure, a relatively pure assay of incentive salience. |
2013-10-28 |
2023-08-12 |
Not clear |
| Omar Ouachikh, Wisam Dieb, Franck Durif, Aziz Hafid. Differential behavioral reinforcement effects of dopamine receptor agonists in the rat with bilateral lesion of the posterior ventral tegmental area. Behavioural brain research. vol 252. 2013-10-28. PMID:23727149. |
we hypothesize that dopamine replacement therapy is responsible for the potential reinforcement effect in parkinson's disease by acting on the neuronal reward circuitry. |
2013-10-28 |
2023-08-12 |
rat |