| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Huikun Wang, Carl R Lupic. Release of endogenous cannabinoids from ventral tegmental area dopamine neurons and the modulation of synaptic processes. Progress in neuro-psychopharmacology & biological psychiatry. vol 52. 2014-12-12. PMID:24495779. |
therefore, understanding how endocannabinoids are mobilized to modulate synaptic inputs impinging on midbrain dopamine neurons is crucial to a complete understanding of the roles that these molecules play in reward behavior, drug abuse and addiction. |
2014-12-12 |
2023-08-12 |
Not clear |
| Tohru Kodama, Kazuo Hikosaka, Yoshiko Honda, Takashi Kojima, Masataka Watanab. Higher dopamine release induced by less rather than more preferred reward during a working memory task in the primate prefrontal cortex. Behavioural brain research. vol 266. 2014-12-12. PMID:24556206. |
higher dopamine release induced by less rather than more preferred reward during a working memory task in the primate prefrontal cortex. |
2014-12-12 |
2023-08-12 |
monkey |
| Beata Bystrowska, Irena Smaga, Małgorzata Frankowska, Małgorzata Fili. Changes in endocannabinoid and N-acylethanolamine levels in rat brain structures following cocaine self-administration and extinction training. Progress in neuro-psychopharmacology & biological psychiatry. vol 50. 2014-12-11. PMID:24334211. |
in addition, several drugs targeting ecbs and/or naes are implicated in reward and/or seeking behaviours related to the stimulation of dopamine systems in the brain. |
2014-12-11 |
2023-08-12 |
rat |
| C H Ponce, M S Brown, J S Silva, P Schlegel, W Rounds, D M Hallfor. Effects of a dietary sweetener on growth performance and health of stressed beef calves and on diet digestibility and plasma and urinary metabolite concentrations of healthy calves. Journal of animal science. vol 92. issue 4. 2014-12-10. PMID:24663208. |
saccharin supplementation reduced plasma homocysteine and increased urinary excretion of vanillymandelic acid, suggesting an improved activity of the dopamine reward system. |
2014-12-10 |
2023-08-12 |
Not clear |
| Paul J Cocker, Bernard Le Foll, Robert D Rogers, Catharine A Winstanle. A selective role for dopamine D₄ receptors in modulating reward expectancy in a rodent slot machine task. Biological psychiatry. vol 75. issue 10. 2014-12-03. PMID:24094512. |
a selective role for dopamine d₄ receptors in modulating reward expectancy in a rodent slot machine task. |
2014-12-03 |
2023-08-12 |
rat |
| Alessia Salamone, Stefania Zappettini, Massimo Grilli, Guendalina Olivero, Paula Agostinho, Angelo R Tomé, Jiayang Chen, Anna Pittaluga, Rodrigo A Cunha, Mario March. Prolonged nicotine exposure down-regulates presynaptic NMDA receptors in dopaminergic terminals of the rat nucleus accumbens. Neuropharmacology. vol 79. 2014-12-03. PMID:24373903. |
the presynaptic control of dopamine release in the nucleus accumbens (nac) by glutamate and acetylcholine has a profound impact on reward signaling. |
2014-12-03 |
2023-08-12 |
rat |
| Koraly Pérez-Edgar, Jillian E Hardee, Amanda E Guyer, Brenda E Benson, Eric E Nelson, Elena Gorodetsky, David Goldman, Nathan A Fox, Daniel S Pine, Monique Erns. DRD4 and striatal modulation of the link between childhood behavioral inhibition and adolescent anxiety. Social cognitive and affective neuroscience. vol 9. issue 4. 2014-12-01. PMID:23314010. |
independent studies link reward hyper-responsivity to bi, adolescent anxiety and dopamine gene variants. |
2014-12-01 |
2023-08-12 |
human |
| Ning Wang, Ping Su, Ying Zhang, Jie Lu, Baoming Xing, Kai Kang, Wenqi Li, Yun Wan. Protein kinase D1-dependent phosphorylation of dopamine D1 receptor regulates cocaine-induced behavioral responses. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 5. 2014-12-01. PMID:24362306. |
the dopamine (da) d1 receptor (d1r) is critically involved in reward and drug addiction. |
2014-12-01 |
2023-08-12 |
rat |
| Dan P Covey, Mitchell F Roitman, Paul A Garri. Illicit dopamine transients: reconciling actions of abused drugs. Trends in neurosciences. vol 37. issue 4. 2014-12-01. PMID:24656971. |
phasic increases in brain dopamine are required for cue-directed reward seeking. |
2014-12-01 |
2023-08-12 |
Not clear |
| Dan P Covey, Mitchell F Roitman, Paul A Garri. Illicit dopamine transients: reconciling actions of abused drugs. Trends in neurosciences. vol 37. issue 4. 2014-12-01. PMID:24656971. |
although compelling within the framework of appetitive behavior, the view that illicit drugs hijack reward circuits by hyperactivating these dopamine transients is inconsistent with established psychostimulant pharmacology. |
2014-12-01 |
2023-08-12 |
Not clear |
| Dan P Covey, Mitchell F Roitman, Paul A Garri. Illicit dopamine transients: reconciling actions of abused drugs. Trends in neurosciences. vol 37. issue 4. 2014-12-01. PMID:24656971. |
consequently, to mimic natural rewards and exploit reward circuits, dopamine transients must be elicited de novo. |
2014-12-01 |
2023-08-12 |
Not clear |
| A R Revitsky, L C Klei. Role of ghrelin in drug abuse and reward-relevant behaviors: a burgeoning field and gaps in the literature. Current drug abuse reviews. vol 6. issue 3. 2014-11-24. PMID:24502454. |
following a review of the small body of literature examining the effects of ghrelin administration on the dopamine reward pathway, we present a model of the relationship between ghrelin and dopaminergic reward activation. |
2014-11-24 |
2023-08-12 |
Not clear |
| A R Revitsky, L C Klei. Role of ghrelin in drug abuse and reward-relevant behaviors: a burgeoning field and gaps in the literature. Current drug abuse reviews. vol 6. issue 3. 2014-11-24. PMID:24502454. |
specifically, ghrelin acts on ghrelin receptors (ghs-r1a) in the ventral tegmental area (vta) and lateral dorsal tegmental nucleus (ldtg) to stimulate the mesolimbic dopamine reward pathway, which results in increased rewarding behaviors in rodents. |
2014-11-24 |
2023-08-12 |
Not clear |
| A R Revitsky, L C Klei. Role of ghrelin in drug abuse and reward-relevant behaviors: a burgeoning field and gaps in the literature. Current drug abuse reviews. vol 6. issue 3. 2014-11-24. PMID:24502454. |
this review highlights gaps in the literature, including a lack of examination of sex- or age-related differences in the effects of ghrelin on dopamine reward processes. |
2014-11-24 |
2023-08-12 |
Not clear |
| Laura Dazzi, Giuseppe Talani, Francesca Biggio, Cinzia Utzeri, Valeria Lallai, Valentina Licheri, Stefano Lutzu, Maria Cristina Mostallino, Pietro Paolo Secci, Giovanni Biggio, Enrico Sann. Involvement of the cannabinoid CB1 receptor in modulation of dopamine output in the prefrontal cortex associated with food restriction in rats. PloS one. vol 9. issue 3. 2014-11-18. PMID:24632810. |
increase in dopamine output on corticolimbic structures, such as medial prefrontal cortex (mpfc) and nucleus accumbens, has been related to reward effects associated with palatable food or food presentation after a fasting period. |
2014-11-18 |
2023-08-12 |
rat |
| Eirik Søvik, Naïla Even, Catherine W Radford, Andrew B Barro. Cocaine affects foraging behaviour and biogenic amine modulated behavioural reflexes in honey bees. PeerJ. vol 2. 2014-11-18. PMID:25405075. |
since insect reward responses involve both octopamine and dopamine signalling, we conclude that cocaine treatment altered diverse reward-related aspects of behaviour in bees. |
2014-11-18 |
2023-08-13 |
bee |
| Hyoung F Kim, Ali Ghazizadeh, Okihide Hikosak. Separate groups of dopamine neurons innervate caudate head and tail encoding flexible and stable value memories. Frontiers in neuroanatomy. vol 8. 2014-11-17. PMID:25400553. |
dopamine (da) neurons are thought to be critical for reward value-based learning by modifying synaptic transmissions in the striatum. |
2014-11-17 |
2023-08-13 |
monkey |
| b' Karin Vadovi\\xc4\\x8dov\\xc3\\xa. Affective and cognitive prefrontal cortex projections to the lateral habenula in humans. Frontiers in human neuroscience. vol 8. 2014-11-11. PMID:25386128.' |
i predicted no corticohabenular projections from the reward processing regions: medial ofc (mofc) and ventral acc (vacc) because both respond most strongly to good, high valued stimuli and outcomes, inducing dopamine and serotonin release. |
2014-11-11 |
2023-08-13 |
Not clear |
| Paul Fredrickson, Mona Boules, Bethany Stennett, Elliott Richelso. Neurotensin agonist attenuates nicotine potentiation to cocaine sensitization. Behavioral sciences (Basel, Switzerland). vol 4. issue 1. 2014-11-07. PMID:25379267. |
neurotensin (nt) is a 13-amino acid neuropeptide that modulates dopamine, acetylcholine, glutamate, and gaba neurotransmission in brain reward pathways. |
2014-11-07 |
2023-08-13 |
rat |
| F Ivy Carroll, Bruce E Blough, S Wayne Mascarella, Hernán A Navarro, Ronald J Lukas, M Imad Dama. Bupropion and bupropion analogs as treatments for CNS disorders. Advances in pharmacology (San Diego, Calif.). vol 69. 2014-11-06. PMID:24484978. |
however, it seems likely that efficacy is due to a combination of the effects of bupropion and/or its active metabolite (2s,3s)-hydroxybupropion involving the inhibition of reuptake of dopamine (da) and ne in reward centers of the brain and the noncompetitive antagonism of α4β2- and α3β4*-nachrs. |
2014-11-06 |
2023-08-12 |
Not clear |