| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F Nees, S H Witt, R Dinu-Biringer, A Lourdusamy, J Tzschoppe, S Vollstädt-Klein, S Millenet, C Bach, L Poustka, T Banaschewski, G J Barker, A L W Bokde, U Bromberg, C Büchel, P J Conrod, J Frank, V Frouin, J Gallinat, H Garavan, P Gowland, A Heinz, B Ittermann, K Mann, J-L Martinot, T Paus, Z Pausova, T W Robbins, M N Smolka, M Rietschel, G Schumann, H Flo. BDNF Val66Met and reward-related brain function in adolescents: role for early alcohol consumption. Alcohol (Fayetteville, N.Y.). vol 49. issue 2. 2015-11-20. PMID:25650137. |
the nonsynonymous single nucleotide polymorphism in the brain-derived neurotrophic factor (bdnf) gene (rs6265/val66met) modulates the central nervous system activity of neurotransmitters involved in reward processing such as serotonin, dopamine, and glutamate. |
2015-11-20 |
2023-08-13 |
rat |
| Kathleen Borgmann, Anuja Ghorpad. HIV-1, methamphetamine and astrocytes at neuroinflammatory Crossroads. Frontiers in microbiology. vol 6. 2015-11-20. PMID:26579077. |
further, meth triggers the dopamine reward pathway and leads to impaired neuronal activity and direct toxicity. |
2015-11-20 |
2023-08-13 |
human |
| Thomas H B FitzGerald, Raymond J Dolan, Karl Fristo. Dopamine, reward learning, and active inference. Frontiers in computational neuroscience. vol 9. 2015-11-20. PMID:26581305. |
this is supported by studies where optogenetic stimulation of dopamine neurons can stand in lieu of actual reward. |
2015-11-20 |
2023-08-13 |
Not clear |
| Jung Hoon Shin, Martín F Adrover, Jürgen Wess, Veronica A Alvare. Muscarinic regulation of dopamine and glutamate transmission in the nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 26. 2015-11-17. PMID:26080439. |
cholinergic transmission in the striatum functions as a key modulator of dopamine (da) transmission and synaptic plasticity, both of which are required for reward and motor learning. |
2015-11-17 |
2023-08-13 |
Not clear |
| Eric Mooshagian, Aysha Keisler, Trelawny Zimmermann, Janell M Schweickert, Eric M Wasserman. Modulation of corticospinal excitability by reward depends on task framing. Neuropsychologia. vol 68. 2015-11-13. PMID:25543022. |
the dopamine neuron response to conditioned stimuli encodes reward probability and outcome uncertainty, or the extent to which the outcome of a situation is known. |
2015-11-13 |
2023-08-13 |
human |
| Andrew Chih Wei Huang, Shiun Wang, José Jiun-Shian Wu, Cheng Chung Wan. Footshock facilitates methamphetamine-induced conditioned suppression through HPA axis, not dopamine. Physiology & behavior. vol 141. 2015-11-05. PMID:25592442. |
the present study examined whether footshock can enhance methamphetamine (mamph)-induced conditioned suppression and whether this effect involves the dopamine (da) reward system or hypothalamic-pituitary-adrenal (hpa) axis. |
2015-11-05 |
2023-08-13 |
rat |
| Tobias U Hauser, Laurence T Hunt, Reto Iannaccone, Susanne Walitza, Daniel Brandeis, Silvia Brem, Raymond J Dola. Temporally Dissociable Contributions of Human Medial Prefrontal Subregions to Reward-Guided Learning. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 32. 2015-11-05. PMID:26269631. |
it is unclear whether these signals reflect parallel processing of a common synchronous input to both regions, for example from mesocortical dopamine, or separate and consecutive stages in reward processing. |
2015-11-05 |
2023-08-13 |
human |
| Ting Yan, Joshua Dominic Rizak, Jianhong Wang, Shangchuan Yang, Yuanye Ma, Xintian H. Severe dopaminergic neuron loss in rhesus monkey brain impairs morphine-induced conditioned place preference. Frontiers in behavioral neuroscience. vol 9. 2015-11-03. PMID:26528155. |
it is well known that dopamine (da) is critical for reward, but the precise role of da in reward remains uncertain. |
2015-11-03 |
2023-08-13 |
monkey |
| Susanne Becker, Wiebke Gandhi, Nathaniel M Elfassy, Petra Schweinhard. The role of dopamine in the perceptual modulation of nociceptive stimuli by monetary wins or losses. The European journal of neuroscience. vol 38. issue 7. 2015-10-30. PMID:23841460. |
however, effects on the motivation to endure or to avoid nociceptive stimulation would be more in line with dopamine's well-established role in the motivation to obtain reward. |
2015-10-30 |
2023-08-12 |
human |
| Jeremiah Y Cohe. Dopamine and serotonin signals for reward across time scales. Science (New York, N.Y.). vol 350. issue 6256. 2015-10-28. PMID:26430113. |
dopamine and serotonin signals for reward across time scales. |
2015-10-28 |
2023-08-13 |
Not clear |
| Jae-Ick Kim, Subhashree Ganesan, Sarah X Luo, Yu-Wei Wu, Esther Park, Eric J Huang, Lu Chen, Jun B Din. Aldehyde dehydrogenase 1a1 mediates a GABA synthesis pathway in midbrain dopaminergic neurons. Science (New York, N.Y.). vol 350. issue 6256. 2015-10-28. PMID:26430123. |
midbrain dopamine neurons are an essential component of the basal ganglia circuitry, playing key roles in the control of fine movement and reward. |
2015-10-28 |
2023-08-13 |
Not clear |
| Amanda Laque, Sangho Yu, Emily Qualls-Creekmore, Sarah Gettys, Candice Schwartzenburg, Kelly Bui, Christopher Rhodes, Hans-Rudolf Berthoud, Christopher D Morrison, Brenda K Richards, Heike Münzber. Leptin modulates nutrient reward via inhibitory galanin action on orexin neurons. Molecular metabolism. vol 4. issue 10. 2015-10-27. PMID:26500842. |
food reward requires stimulation of midbrain dopamine neurons and is modulated by central leptin action, but the exact central mechanisms remain unclear. |
2015-10-27 |
2023-08-13 |
Not clear |
| Sonja Yokum, C Nathan Marti, Andrew Smolen, Eric Stic. Relation of the multilocus genetic composite reflecting high dopamine signaling capacity to future increases in BMI. Appetite. vol 87. 2015-10-26. PMID:25523644. |
because food intake exerts its rewarding effect by increasing dopamine (da) signaling in reward circuitry, it theoretically follows that individuals with a greater number of genotypes putatively associated with high da signaling capacity are at increased risk for overeating and subsequent weight gain. |
2015-10-26 |
2023-08-13 |
human |
| Lorenz Deserno, Anne Beck, Quentin J M Huys, Robert C Lorenz, Ralph Buchert, Hans-Georg Buchholz, Michail Plotkin, Yoshitaka Kumakara, Paul Cumming, Hans-Jochen Heinze, Anthony A Grace, Michael A Rapp, Florian Schlagenhauf, Andreas Hein. Chronic alcohol intake abolishes the relationship between dopamine synthesis capacity and learning signals in the ventral striatum. The European journal of neuroscience. vol 41. issue 4. 2015-10-26. PMID:25546072. |
drugs of abuse elicit dopamine release in the ventral striatum, possibly biasing dopamine-driven reinforcement learning towards drug-related reward at the expense of non-drug-related reward. |
2015-10-26 |
2023-08-13 |
human |
| Gregory P Strauss, James A Waltz, James M Gol. A review of reward processing and motivational impairment in schizophrenia. Schizophrenia bulletin. vol 40 Suppl 2. 2015-10-23. PMID:24375459. |
aberrant cortical-striatal interactions may be involved with multiple reward processing abnormalities, including: (1) dopamine-mediated basal ganglia systems that support reinforcement learning and the ability to predict cues that lead to rewarding outcomes; (2) orbitofrontal cortex-driven deficits in generating, updating, and maintaining value representations; (3) aberrant effort-value computations, which may be mediated by disrupted anterior cingulate cortex and midbrain dopamine functioning; and (4) altered activation of the prefrontal cortex, which is important for generating exploratory behaviors in environments where reward outcomes are uncertain. |
2015-10-23 |
2023-08-12 |
Not clear |
| Shin-ichi Adachi, Ai Eguchi, Kazuhiro Sakamoto, Hiroki Asano, Yasuko Manabe, Shigenobu Matsumura, Satoshi Tsuzuki, Kazuo Inoue, Tohru Fushik. Behavioral palatability of dietary fatty acids correlates with the intracellular calcium ion levels induced by the fatty acids in GPR120-expressing cells. Biomedical research (Tokyo, Japan). vol 35. issue 6. 2015-10-22. PMID:25743342. |
we also showed that the lcfa (1% linoleic acid) increased the extracellular dopamine (da) level in the nucleus accumbens (nac), which participates in reward behavior. |
2015-10-22 |
2023-08-13 |
mouse |
| S H Ridgway, P W Moore, D A Carder, T A Roman. Forward shift of feeding buzz components of dolphins and belugas during associative learning reveals a likely connection to reward expectation, pleasure and brain dopamine activation. The Journal of experimental biology. vol 217. issue Pt 16. 2015-10-21. PMID:25122919. |
our novel observation suggests that the dopamine reward system is active in cetacean brains. |
2015-10-21 |
2023-08-13 |
Not clear |
| Z J Hall, S D Healy, S L Meddl. A role for nonapeptides and dopamine in nest-building behaviour. Journal of neuroendocrinology. vol 27. issue 2. 2015-10-21. PMID:25514990. |
because the nonapeptides, mesotocin and vasotocin and the neurotransmitter, dopamine, play important roles in avian social behaviour, we tested the hypothesis that mesotocinergic-vasotocinergic and dopaminergic neuronal populations in the social behaviour network and dopaminergic reward system, respectively, are active during nest building. |
2015-10-21 |
2023-08-13 |
Not clear |
| Daisuke Nishizawa, Ken-ichi Fukuda, Shinya Kasai, Yasukazu Ogai, Junko Hasegawa, Naomi Sato, Hidetaka Yamada, Fumihiko Tanioka, Haruhiko Sugimura, Masakazu Hayashida, Kazutaka Iked. Association between KCNJ6 (GIRK2) gene polymorphism rs2835859 and post-operative analgesia, pain sensitivity, and nicotine dependence. Journal of pharmacological sciences. vol 126. issue 3. 2015-10-19. PMID:25346042. |
g-protein-activated inwardly rectifying potassium (girk) channels are expressed in many tissues and activated by several gi/o protein-coupled receptors, such as opioid and dopamine receptors, and thus are known to be involved in the modulation of opioid-induced analgesia, pain, and reward. |
2015-10-19 |
2023-08-13 |
Not clear |
| Bianca C Wittmann, Mark D'Esposit. Levodopa administration modulates striatal processing of punishment-associated items in healthy participants. Psychopharmacology. vol 232. issue 1. 2015-10-16. PMID:24923987. |
on a neural level, reward and its predictors are associated with increased firing of dopaminergic neurons, whereas punishment processing has been linked to the serotonergic system and to decreases in dopamine transmission. |
2015-10-16 |
2023-08-13 |
human |