| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Samuel T Mattox, Fernando Valle-Inclán, Steven A Hackle. Psychophysiological evidence for impaired reward anticipation in Parkinson's disease. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. vol 117. issue 10. 2006-12-15. PMID:16920018. |
according to a widely held view, mesencephalic dopamine neurons mediate feedback-based learning by broadcasting an error signal that indexes the difference between anticipated and actual response-contingent reward. |
2006-12-15 |
2023-08-12 |
Not clear |
| Taku Nagai, Mina Ito, Noritaka Nakamichi, Hiroyuki Mizoguchi, Hiroyuki Kamei, Ayumi Fukakusa, Toshitaka Nabeshima, Kazuhiro Takuma, Kiyofumi Yamad. The rewards of nicotine: regulation by tissue plasminogen activator-plasmin system through protease activated receptor-1. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 47. 2006-12-15. PMID:17122062. |
here we show that the tissue plasminogen activator (tpa)-plasmin system regulates nicotine-induced reward and dopamine release by activating protease activated receptor-1 (par1). |
2006-12-15 |
2023-08-12 |
mouse |
| T M Mosher, J G Smith, A J Greensha. Aversive stimulus properties of the 5-HT2C receptor agonist WAY 161503 in rats. Neuropharmacology. vol 51. issue 3. 2006-12-14. PMID:16844150. |
serotonin2c (5-ht2c) receptors may influence motivation and reward through effects on the mesocorticolimbic dopamine (da) system. |
2006-12-14 |
2023-08-12 |
rat |
| M E Walton, S W Kennerley, D M Bannerman, P E M Phillips, M F S Rushwort. Weighing up the benefits of work: behavioral and neural analyses of effort-related decision making. Neural networks : the official journal of the International Neural Network Society. vol 19. issue 8. 2006-12-12. PMID:16949252. |
these calculations appear to be critically mediated by the anterior cingulate cortex (acc) and mesolimbic dopamine (da) pathways, with damage to either causing a bias towards options that are easily obtained but yield relatively smaller reward rather than alternatives that require more work but result in greater reward. |
2006-12-12 |
2023-08-12 |
monkey |
| Ying Jin, Dafang Chen, Yonghua Hu, Song Guo, Hongqiang Sun, Aili Lu, Xiaoyan Zhang, Lingsong L. Association between monoamine oxidase gene polymorphisms and smoking behaviour in Chinese males. The international journal of neuropsychopharmacology. vol 9. issue 5. 2006-12-11. PMID:16207390. |
monoamine oxidase (mao) is a critical metabolic enzyme of dopamine, which is a key neurotransmitter of the mesolimbic reward pathway in the human brain. |
2006-12-11 |
2023-08-12 |
human |
| Arlene C Pak, Charles R Ashby, Christian A Heidbreder, Maria Pilla, Jeremy Gilbert, Zheng-Xiong Xi, Eliot L Gardne. The selective dopamine D3 receptor antagonist SB-277011A reduces nicotine-enhanced brain reward and nicotine-paired environmental cue functions. The international journal of neuropsychopharmacology. vol 9. issue 5. 2006-12-11. PMID:16942635. |
the selective dopamine d3 receptor antagonist sb-277011a reduces nicotine-enhanced brain reward and nicotine-paired environmental cue functions. |
2006-12-11 |
2023-08-12 |
rat |
| Arlene C Pak, Charles R Ashby, Christian A Heidbreder, Maria Pilla, Jeremy Gilbert, Zheng-Xiong Xi, Eliot L Gardne. The selective dopamine D3 receptor antagonist SB-277011A reduces nicotine-enhanced brain reward and nicotine-paired environmental cue functions. The international journal of neuropsychopharmacology. vol 9. issue 5. 2006-12-11. PMID:16942635. |
increasing evidence suggests that enhanced dopamine (da) neurotransmission in the nucleus accumbens (nac) may play a role in mediating the reward and reinforcement produced by addictive drugs and in the attentional processing of drug-associated environmental cues. |
2006-12-11 |
2023-08-12 |
rat |
| Aaron W Pardini, Hong T Nguyen, Dianne P Figlewicz, Denis G Baskin, Diana L Williams, Francis Kim, Michael W Schwart. Distribution of insulin receptor substrate-2 in brain areas involved in energy homeostasis. Brain research. vol 1112. issue 1. 2006-11-28. PMID:16925984. |
irs-2 protein was also found in the ventral tegmental area (vta), an important area for reward perception, and was detected in dopamine neurons in this brain area. |
2006-11-28 |
2023-08-12 |
rat |
| Christian O Alberto, Robert B Trask, Michelle E Quinlan, Michiru Hirasaw. Bidirectional dopaminergic modulation of excitatory synaptic transmission in orexin neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 39. 2006-11-27. PMID:17005867. |
dopamine (da), in turn, inhibits the reward pathway and food intake through its action in the lh/pfa. |
2006-11-27 |
2023-08-12 |
rat |
| Elisabet Jerlhag, Emil Egecioglu, Suzanne L Dickson, Malin Andersson, Lennart Svensson, Jörgen A Enge. Ghrelin stimulates locomotor activity and accumbal dopamine-overflow via central cholinergic systems in mice: implications for its involvement in brain reward. Addiction biology. vol 11. issue 1. 2006-11-09. PMID:16759336. |
the cholinergic afferents to the ventral tegmental area have been implicated in natural reward and in regulating mesoaccumbal dopamine neurons. |
2006-11-09 |
2023-08-12 |
mouse |
| S V Koroleva, A A Nikolaeva, I P Ashmari. [Interactions between dopamine, serotonin and other internal reinforcement factors]. Izvestiia Akademii nauk. Seriia biologicheskaia. issue 4. 2006-11-09. PMID:17022478. |
the big volume of odd literature data (period 1960-2005) was investigated for analysis and estimation of interactions between dopamine (da), serotonin (5-ht), reward factors and basic members of regulatory peptide (rp) families. |
2006-11-09 |
2023-08-12 |
Not clear |
| Jonathan D Hommel, Richard Trinko, Robert M Sears, Dan Georgescu, Zong-Wu Liu, Xiao-Bing Gao, Jeremy J Thurmon, Michela Marinelli, Ralph J DiLeon. Leptin receptor signaling in midbrain dopamine neurons regulates feeding. Neuron. vol 51. issue 6. 2006-11-07. PMID:16982424. |
the vta contains dopamine neurons that are important in modulating motivated behavior, addiction, and reward. |
2006-11-07 |
2023-08-12 |
Not clear |
| b' Esa Meririnne, Miina Kajos, Aino Kankaanp\\xc3\\xa4\\xc3\\xa4, Timo Sepp\\xc3\\xa4l\\xc3\\xa. Rewarding properties of 1-benzylpiperazine, a new drug of abuse, in rats. Basic & clinical pharmacology & toxicology. vol 98. issue 4. 2006-10-26. PMID:16623856.' |
furthermore, the mechanisms of the 1-benzylpiperazine reward were investigated using selected dopamine and serotonin receptor antagonists. |
2006-10-26 |
2023-08-12 |
human |
| Peter Kirsch, Martin Reuter, Daniela Mier, Tina Lonsdorf, Rudolf Stark, Bernd Gallhofer, Dieter Vaitl, Jürgen Henni. Imaging gene-substance interactions: the effect of the DRD2 TaqIA polymorphism and the dopamine agonist bromocriptine on the brain activation during the anticipation of reward. Neuroscience letters. vol 405. issue 3. 2006-10-24. PMID:16901644. |
imaging gene-substance interactions: the effect of the drd2 taqia polymorphism and the dopamine agonist bromocriptine on the brain activation during the anticipation of reward. |
2006-10-24 |
2023-08-12 |
human |
| Peter Kirsch, Martin Reuter, Daniela Mier, Tina Lonsdorf, Rudolf Stark, Bernd Gallhofer, Dieter Vaitl, Jürgen Henni. Imaging gene-substance interactions: the effect of the DRD2 TaqIA polymorphism and the dopamine agonist bromocriptine on the brain activation during the anticipation of reward. Neuroscience letters. vol 405. issue 3. 2006-10-24. PMID:16901644. |
dopamine is known as the main neurotransmitter modulating the activation of the reward system of the brain. |
2006-10-24 |
2023-08-12 |
human |
| Peter Kirsch, Martin Reuter, Daniela Mier, Tina Lonsdorf, Rudolf Stark, Bernd Gallhofer, Dieter Vaitl, Jürgen Henni. Imaging gene-substance interactions: the effect of the DRD2 TaqIA polymorphism and the dopamine agonist bromocriptine on the brain activation during the anticipation of reward. Neuroscience letters. vol 405. issue 3. 2006-10-24. PMID:16901644. |
the drd2 taqia polymorphism is associated with dopamine d2 receptor density which plays an important role in the context of reward. |
2006-10-24 |
2023-08-12 |
human |
| R de la Fuente-Fernández, S Lidstone, A J Stoess. Placebo effect and dopamine release. Journal of neural transmission. Supplementum. issue 70. 2006-10-24. PMID:17017561. |
in addition, as dopamine is the major neurotransmitter in the reward circuitry, the model predicts that the release of dopamine in the ventral striatum could be involved in mediating placebo responses not only in parkinson's but also in other medical conditions. |
2006-10-24 |
2023-08-12 |
Not clear |
| Paul D Shepard, Henry H Holcomb, James M Gol. Schizophrenia in translation: the presence of absence: habenular regulation of dopamine neurons and the encoding of negative outcomes. Schizophrenia bulletin. vol 32. issue 3. 2006-10-18. PMID:16717257. |
there is now a compelling body of evidence from nonhuman primates that suggests transient decreases in dopamine cell activity may reflect the occurrence of unexpected negative outcomes, such as the absence of an expected reward, and, generalizing to the human, the occurrence of negative feedback or the absence of expected reward. |
2006-10-18 |
2023-08-12 |
human |
| Feng C Zhou, Robert N Sahr, Youssef Sari, Kamran Behbahan. Glutamate and dopamine synaptic terminals in extended amygdala after 14-week chronic alcohol drinking in inbred alcohol-preferring rats. Alcohol (Fayetteville, N.Y.). vol 39. issue 1. 2006-10-06. PMID:16938628. |
alcohol has been shown to affect glutamate (glu) and dopamine (da) release and their correlated receptors in the key reward center--extended amygdala--which includes the shell of nucleus accumbens (snac) and central nucleus of amygdala (camg). |
2006-10-06 |
2023-08-12 |
rat |
| Derik Hermann, Michael N Smolka, Jana Wrase, Sabine Klein, Jörg Nikitopoulos, Alexander Georgi, Dieter F Braus, Herta Flor, Karl Mann, Andreas Hein. Blockade of cue-induced brain activation of abstinent alcoholics by a single administration of amisulpride as measured with fMRI. Alcoholism, clinical and experimental research. vol 30. issue 8. 2006-09-29. PMID:16899037. |
once alcohol dependence is established, alcohol-associated cues may induce dopamine release in the reward system, which is accompanied by alcohol craving and may lead to relapse. |
2006-09-29 |
2023-08-12 |
Not clear |