| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A M Young, M H Joseph, J A Gra. Latent inhibition of conditioned dopamine release in rat nucleus accumbens. Neuroscience. vol 54. issue 1. 1993-07-20. PMID:8515846. |
many lines of evidence point to the nucleus accumbens as being part of an anatomical substrate for reward. |
1993-07-20 |
2023-08-12 |
rat |
| S T Cunningham, A E Kelle. Evidence for opiate-dopamine cross-sensitization in nucleus accumbens: studies of conditioned reward. Brain research bulletin. vol 29. issue 5. 1992-12-15. PMID:1422864. |
evidence for opiate-dopamine cross-sensitization in nucleus accumbens: studies of conditioned reward. |
1992-12-15 |
2023-08-11 |
rat |
| S T Cunningham, A E Kelle. Evidence for opiate-dopamine cross-sensitization in nucleus accumbens: studies of conditioned reward. Brain research bulletin. vol 29. issue 5. 1992-12-15. PMID:1422864. |
we investigated opiate-amphetamine interactions within the nucleus accumbens in responding for conditioned reward. |
1992-12-15 |
2023-08-11 |
rat |
| S T Cunningham, A E Kelle. Opiate infusion into nucleus accumbens: contrasting effects on motor activity and responding for conditioned reward. Brain research. vol 588. issue 1. 1992-11-12. PMID:1327405. |
opiate infusion into nucleus accumbens: contrasting effects on motor activity and responding for conditioned reward. |
1992-11-12 |
2023-08-11 |
rat |
| S T Cunningham, A E Kelle. Opiate infusion into nucleus accumbens: contrasting effects on motor activity and responding for conditioned reward. Brain research. vol 588. issue 1. 1992-11-12. PMID:1327405. |
in the present experiments, we examined the roles of opiate receptor subtypes in the nucleus accumbens in spontaneous motor behavior and responding for conditioned reward. |
1992-11-12 |
2023-08-11 |
rat |
| C L Duvauchelle, M Levitin, L A MacConell, L K Lee, A Ettenber. Opposite effects of prefrontal cortex and nucleus accumbens infusions of flupenthixol on stimulant-induced locomotion and brain stimulation reward. Brain research. vol 576. issue 1. 1992-10-06. PMID:1515903. |
opposite effects of prefrontal cortex and nucleus accumbens infusions of flupenthixol on stimulant-induced locomotion and brain stimulation reward. |
1992-10-06 |
2023-08-11 |
Not clear |
| C L Duvauchelle, M Levitin, L A MacConell, L K Lee, A Ettenber. Opposite effects of prefrontal cortex and nucleus accumbens infusions of flupenthixol on stimulant-induced locomotion and brain stimulation reward. Brain research. vol 576. issue 1. 1992-10-06. PMID:1515903. |
these behavioral findings suggest a dopamine-mediated modulatory role for the pfc over reward relevant elements within the nucleus accumbens. |
1992-10-06 |
2023-08-11 |
Not clear |
| H C Fibiger, A G Phillips, E E Brow. The neurobiology of cocaine-induced reinforcement. Ciba Foundation symposium. vol 166. 1992-09-03. PMID:1638924. |
a critical review of the literature suggests that microdialysis results are generally consistent with a role for mesolimbic dopamine in cocaine-induced reward, although it does not seem to be the case that animals will work to maintain consistent increases in extracellular concentrations of dopamine in the nucleus accumbens in all experimental conditions. |
1992-09-03 |
2023-08-11 |
Not clear |
| G F Koo. Neural mechanisms of drug reinforcement. Annals of the New York Academy of Sciences. vol 654. 1992-08-17. PMID:1632582. |
the brain substrates involved in the effect of cocaine on brain stimulation reward, in the psychomotor activation associated with cocaine, and in cocaine self-administration appear to be focused on the medial forebrain bundle and its connections with the basal forebrain, notably the nucleus accumbens. |
1992-08-17 |
2023-08-11 |
rat |
| G F Koo. Drugs of abuse: anatomy, pharmacology and function of reward pathways. Trends in pharmacological sciences. vol 13. issue 5. 1992-07-14. PMID:1604710. |
data implicating dopamine and opioid systems in indirect sympathomimetic and opiate reward include critical elements in both the nucleus accumbens and ventral tegmental areas. |
1992-07-14 |
2023-08-11 |
Not clear |
| A Herz, T S Shippenberg, R Bals-Kubik, R Spanage. [Opiate addiction. Pharmacologic and biochemical aspects]. Arzneimittel-Forschung. vol 42. issue 2A. 1992-06-16. PMID:1586396. |
opposite effects on da are observed in response to microinjections of selective antagonists for these receptor types, suggesting the existence of tonically active endogenous opioid systems which maintain da release in the mesolimbic system: a continuous "reward" tone, probably mediated by beta-endorphin in the ventral tegmentum of the midbrain and an "aversive" tone, mediated by dynorphin in the nucleus accumbens. |
1992-06-16 |
2023-08-11 |
Not clear |
| G Damsma, J G Pfaus, D Wenkstern, A G Phillips, H C Fibige. Sexual behavior increases dopamine transmission in the nucleus accumbens and striatum of male rats: comparison with novelty and locomotion. Behavioral neuroscience. vol 106. issue 1. 1992-05-04. PMID:1313243. |
the preferential increase in da transmission in the nucleus accumbens, compared with that in the striatum, suggests that anticipatory and consummatory aspects of sexual activity may belong to a class of naturally occurring events with reward values that are mediated by da release in the nucleus accumbens. |
1992-05-04 |
2023-08-11 |
rat |
| G P Mark, D S Blander, B G Hoebe. A conditioned stimulus decreases extracellular dopamine in the nucleus accumbens after the development of a learned taste aversion. Brain research. vol 551. issue 1-2. 1991-11-01. PMID:1913157. |
the conditioned taste aversion (cta) paradigm and microdialysis were used to determine if extracellular dopamine in the nucleus accumbens is related to the reward value of a stimulus. |
1991-11-01 |
2023-08-11 |
human |
| D Beitner-Johnson, E J Nestle. Morphine and cocaine exert common chronic actions on tyrosine hydroxylase in dopaminergic brain reward regions. Journal of neurochemistry. vol 57. issue 1. 1991-07-23. PMID:1675665. |
we studied levels of tyrosine hydroxylase immunoreactivity and phosphorylation state in the ventral tegmental area (vta) and nucleus accumbens (nac) in an effort to understand better the mechanisms by which these brain reward regions are influenced by opiates and cocaine. |
1991-07-23 |
2023-08-11 |
Not clear |
| N M White, M G Packard, N Hiro. Place conditioning with dopamine D1 and D2 agonists injected peripherally or into nucleus accumbens. Psychopharmacology. vol 103. issue 2. 1991-06-12. PMID:1674160. |
these results suggest that activation of either d1 or d2 receptors in the nucleus accumbens can produce reward, and that d1 receptors (and possibly also d2 receptors) located elsewhere in the brain or in the periphery may mediate aversive effects. |
1991-06-12 |
2023-08-11 |
rat |
| A E Kelley, J M Delf. Dopamine and conditioned reinforcement. II. Contrasting effects of amphetamine microinjection into the nucleus accumbens with peptide microinjection into the ventral tegmental area. Psychopharmacology. vol 103. issue 2. 1991-06-12. PMID:1709289. |
in contrast, amphetamine (0, 0.2, 2.0, 20 micrograms) injected into the nucleus accumbens markedly enhanced responding for conditioned reward. |
1991-06-12 |
2023-08-11 |
rat |
| A E Kelley, J M Delf. Dopamine and conditioned reinforcement. I. Differential effects of amphetamine microinjections into striatal subregions. Psychopharmacology. vol 103. issue 2. 1991-06-12. PMID:2027920. |
it has been shown that psychostimulants potentiate responding for conditioned reward and there is evidence that the nucleus accumbens is involved in this effect. |
1991-06-12 |
2023-08-11 |
rat |
| J P Chen, W Paredes, J Li, D Smith, J Lowinson, E L Gardne. Delta 9-tetrahydrocannabinol produces naloxone-blockable enhancement of presynaptic basal dopamine efflux in nucleus accumbens of conscious, freely-moving rats as measured by intracerebral microdialysis. Psychopharmacology. vol 102. issue 2. 1991-02-26. PMID:2177204. |
delta 9-thc, at low doses (0.5-1.0 mg/kg), which significantly enhance brain stimulation reward (intracranial self-stimulation), significantly increased da efflux in nucleus accumbens. |
1991-02-26 |
2023-08-11 |
rat |
| M H Joseph, H Hodge. Lever pressing for food reward and changes in dopamine turnover and uric acid in rat caudate and nucleus accumbens studied chronically by in vivo voltammetry. Journal of neuroscience methods. vol 34. issue 1-3. 1991-01-31. PMID:2259235. |
lever pressing for food reward and changes in dopamine turnover and uric acid in rat caudate and nucleus accumbens studied chronically by in vivo voltammetry. |
1991-01-31 |
2023-08-11 |
rat |
| G H Jones, C A Marsden, T W Robbin. Increased sensitivity to amphetamine and reward-related stimuli following social isolation in rats: possible disruption of dopamine-dependent mechanisms of the nucleus accumbens. Psychopharmacology. vol 102. issue 3. 1991-01-17. PMID:2251333. |
in experiment 2, hungry rats were trained to associate a compound light/noise stimulus with sucrose reward and were then implanted with guide cannulae in the nucleus accumbens. |
1991-01-17 |
2023-08-11 |
rat |