| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N D Volkow, J S Fowle. Addiction, a disease of compulsion and drive: involvement of the orbitofrontal cortex. Cerebral cortex (New York, N.Y. : 1991). vol 10. issue 3. 2000-04-27. PMID:10731226. |
here we postulate that while reward circuits (nucleus accumbens, amygdala), which have been central to theories of drug addiction, may be crucial to initiate drug self-administration, the addictive state also involves disruption of circuits involved with compulsive behaviors and with drive. |
2000-04-27 |
2023-08-12 |
human |
| A N Mead, A Vasilaki, C Spyraki, T Duka, D N Stephen. AMPA-receptor involvement in c-fos expression in the medial prefrontal cortex and amygdala dissociates neural substrates of conditioned activity and conditioned reward. The European journal of neuroscience. vol 11. issue 11. 1999-12-28. PMID:10583497. |
ampa-receptor involvement in c-fos expression in the medial prefrontal cortex and amygdala dissociates neural substrates of conditioned activity and conditioned reward. |
1999-12-28 |
2023-08-12 |
mouse |
| A N Mead, A Vasilaki, C Spyraki, T Duka, D N Stephen. AMPA-receptor involvement in c-fos expression in the medial prefrontal cortex and amygdala dissociates neural substrates of conditioned activity and conditioned reward. The European journal of neuroscience. vol 11. issue 11. 1999-12-28. PMID:10583497. |
nbqx failed to block the expression of amphetamine-conditioned place preference, a measure of conditioned reward, or conditioned c-fos expression in the amygdala, an area implicated in the expression of conditioned place preference. |
1999-12-28 |
2023-08-12 |
mouse |
| A Bechara, H Damasio, A R Damasio, G P Le. Different contributions of the human amygdala and ventromedial prefrontal cortex to decision-making. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 13. 1999-07-15. PMID:10377356. |
however, vmf patients were able to generate scrs when they received a reward or a punishment (play money), whereas amygdala patients failed to do so. |
1999-07-15 |
2023-08-12 |
human |
| A I Leshner, G F Koo. Drugs of abuse and the brain. Proceedings of the Association of American Physicians. vol 111. issue 2. 1999-06-29. PMID:10220804. |
drugs of abuse have been hypothesized to produce their rewarding effects by neuropharmacological actions on a common brain reward circuit called the extended amygdala. |
1999-06-29 |
2023-08-12 |
Not clear |
| P W Kalivas, M Nakamur. Neural systems for behavioral activation and reward. Current opinion in neurobiology. vol 9. issue 2. 1999-06-15. PMID:10322190. |
dopaminergic afferents serve to signal changes in rewarding stimuli, whereas glutamatergic input from the amygdala serves to cue behavior to conditioned reward, and afferents from the prefrontal cortex integrate information from short-term memory into behavioral responses. |
1999-06-15 |
2023-08-12 |
Not clear |
| M Barrot, M Marinelli, D N Abrous, F Rougé-Pont, M Le Moal, P V Piazz. Functional heterogeneity in dopamine release and in the expression of Fos-like proteins within the rat striatal complex. The European journal of neuroscience. vol 11. issue 4. 1999-05-20. PMID:10103112. |
the shell is considered as a part of the extended amygdala, and is involved in the control of motivation and reward. |
1999-05-20 |
2023-08-12 |
rat |
| P K Hitchcott, G D Phillip. Effects of intra-amygdala R(+) 7-OH-DPAT on intra-accumbens d-amphetamine-associated learning. II. Instrumental conditioning. Psychopharmacology. vol 140. issue 3. 1999-04-21. PMID:9877011. |
however, the rewarding properties of a drug-associated cs were selectively abolished following activation of amygdala d3 receptors during presentation of the drug reward. |
1999-04-21 |
2023-08-12 |
rat |
| K D Carr, N Kutchukhidze, T H Par. Differential effects of mu and kappa opioid antagonists on Fos-like immunoreactivity in extended amygdala. Brain research. vol 822. issue 1-2. 1999-04-21. PMID:10082881. |
considering the involvement of mesoaccumbens dopamine neurons and components of the 'extended amygdala' in motivated behavior and reward, it was hypothesized that the induction of c-fos by naltrexone accounts for the motivational-affective consequences of opioid antagonism. |
1999-04-21 |
2023-08-12 |
human |
| T Smock, D Albeck, P Star. A peptidergic basis for sexual behavior in mammals. Progress in brain research. vol 119. 1999-03-29. PMID:10074807. |
this role for the medial amygdala complements the proposed role of nearby structures in the consummatory, reward and learned aspects of sexual behavior. |
1999-03-29 |
2023-08-12 |
rat |
| T M Tzschentk. Measuring reward with the conditioned place preference paradigm: a comprehensive review of drug effects, recent progress and new issues. Progress in neurobiology. vol 56. issue 6. 1999-03-23. PMID:9871940. |
brain sites that have been implicated in the mediation of drug-induced place conditioning include the 'traditional' brain reward sites, ventral tegmental area and nucleus accumbens, but the medial prefrontal cortex, ventral pallidum, amygdala and the pedunculopontine tegmental nucleus have also been shown to play important roles in the mediation of place conditioning induced by drugs or natural reinforcers. |
1999-03-23 |
2023-08-12 |
Not clear |
| J A Salinas, N M Whit. Contributions of the hippocampus, amygdala, and dorsal striatum to the response elicited by reward reduction. Behavioral neuroscience. vol 112. issue 4. 1999-03-09. PMID:9733189. |
contributions of the hippocampus, amygdala, and dorsal striatum to the response elicited by reward reduction. |
1999-03-09 |
2023-08-12 |
rat |
| P W Gold, G P Chrouso. The endocrinology of melancholic and atypical depression: relation to neurocircuitry and somatic consequences. Proceedings of the Association of American Physicians. vol 111. issue 1. 1999-02-16. PMID:9893154. |
in addition, recent data reveal important bidirectional interactions between stress-system hormonal factors in depression and neural substrates implicated in many discrete behavioral alterations in depression (e.g., the medial prefrontal cortex, important in shifting affect based on internal and external cues, the mesolimbic dopaminergic reward system, and the amygdala fear system). |
1999-02-16 |
2023-08-12 |
Not clear |
| C K McIntyre, M E Ragozzino, P E Gol. Intra-amygdala infusions of scopolamine impair performance on a conditioned place preference task but not a spatial radial maze task. Behavioural brain research. vol 95. issue 2. 1999-01-29. PMID:9806441. |
thus, intact cholinergic mechanisms in the amygdala are necessary for learning or memory on a cpp task with a high reward component but not performance on a spatial radial maze task with a lower reward component. |
1999-01-29 |
2023-08-12 |
rat |
| E Quertemont, J de Neuville, P De Witt. Changes in the amygdala amino acid microdialysate after conditioning with a cue associated with ethanol. Psychopharmacology. vol 139. issue 1-2. 1998-12-09. PMID:9768544. |
excitatory amino acid neurotransmission within the amygdala has been implicated in learning associations between external stimuli and intrinsic reward values, such that it may play a key role in conditioned drug effects. |
1998-12-09 |
2023-08-12 |
Not clear |
| T H Park, K D Car. Neuroanatomical patterns of fos-like immunoreactivity induced by a palatable meal and meal-paired environment in saline- and naltrexone-treated rats. Brain research. vol 805. issue 1-2. 1998-11-25. PMID:9733960. |
since naltrexone, alone, increased fli in vta, nac shell, central amygdala (cea) and laterodorsal bed nucleus of the stria terminalis (bstld), the blunting of ingestion reward by naltrexone may result from direct or transsynaptic activating effects on opponent neuronal activity within this highly interconnected set of structures that mediate and modulate reward. |
1998-11-25 |
2023-08-12 |
rat |
| W E Pratt, S J Mizumor. Characteristics of basolateral amygdala neuronal firing on a spatial memory task involving differential reward. Behavioral neuroscience. vol 112. issue 3. 1998-10-22. PMID:9676973. |
characteristics of basolateral amygdala neuronal firing on a spatial memory task involving differential reward. |
1998-10-22 |
2023-08-12 |
rat |
| W Schult. Predictive reward signal of dopamine neurons. Journal of neurophysiology. vol 80. issue 1. 1998-08-25. PMID:9658025. |
the dopamine reward signal is supplemented by activity in neurons in striatum, frontal cortex, and amygdala, which process specific reward information but do not emit a global reward prediction error signal. |
1998-08-25 |
2023-08-12 |
Not clear |
| C L Ehlers, C Somes, A L Lopez, P Robled. Long latency event-related potentials in rats: response of amygdala, nucleus accumbens, dorsal hippocampus and frontal cortex to changes in reward characteristics of conditioned stimuli. Brain research. vol 780. issue 1. 1998-04-29. PMID:9473634. |
long latency event-related potentials in rats: response of amygdala, nucleus accumbens, dorsal hippocampus and frontal cortex to changes in reward characteristics of conditioned stimuli. |
1998-04-29 |
2023-08-12 |
rat |
| C L Ehlers, C Somes, A L Lopez, P Robled. Long latency event-related potentials in rats: response of amygdala, nucleus accumbens, dorsal hippocampus and frontal cortex to changes in reward characteristics of conditioned stimuli. Brain research. vol 780. issue 1. 1998-04-29. PMID:9473634. |
significant reductions in the n1 component in cortex and p2 component in amygdala of the rat erp were found as a consequence of removal of the food reward previously associated with the stimuli. |
1998-04-29 |
2023-08-12 |
rat |