| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jingjing Yang, Hongjuan Wang, Huan Chen, Hongwei Hou, Qingyuan H. The association of genetic polymorphisms within the dopaminergic system with nicotine dependence: A narrative review. Heliyon. vol 10. issue 12. 2024-07-18. PMID:39021905. |
nicotine acts on the limbic dopamine reward loop in the midbrain by binding to nicotinic acetylcholine receptors, promoting the release of dopamine, and resulting in a rewarding effect or satisfaction. |
2024-07-18 |
2024-07-20 |
Not clear |
| A A Conti, S Tolomeo, A Baldacchino, J D Steel. Blunted midbrain reward activation during smoking withdrawal: a preliminary study. Frontiers in pharmacology. vol 15. 2024-07-17. PMID:39015373. |
there is pre-clinical evidence from rodents for a dramatic decrease in brain reward function during nicotine withdrawal. |
2024-07-17 |
2024-07-19 |
Not clear |
| Ranjithkumar Chellian, Azin Behnood-Rod, Adriaan W Bruijnzee. The Role of Glucocorticoid and Nicotinic Acetylcholine Receptors in the Reward-Enhancing Effects of Nicotine in the ICSS Procedure in Male and Female Rats. bioRxiv : the preprint server for biology. 2024-07-15. PMID:39005409. |
nicotine lowered the brain reward thresholds and decreased response latencies similarly in male and female rats. |
2024-07-15 |
2024-07-18 |
rat |
| Kimberly N Karin, Mohammed A Mustafa, Justin L Poklis, Belle Buzzi, Joel E Schlosburg, Linda Parker, M Imad Damaj, Aron H Lichtma. N-oleoyl alanine attenuates nicotine reward and spontaneous nicotine withdrawal in mice. Drug and alcohol dependence. vol 259. 2024-04-27. PMID:38676968. |
n-oleoyl alanine attenuates nicotine reward and spontaneous nicotine withdrawal in mice. |
2024-04-27 |
2024-04-30 |
mouse |
| Belle Buzzi, Shakir D AlSharari, David M Walentiny, M Imad Dama. Nelotanserin, a selective 5-HT2A receptor inverse agonist, attenuates aspects of nicotine withdrawal but not reward in mice. Behavioural brain research. 2024-04-27. PMID:38677331. |
nelotanserin, a selective 5-ht2a receptor inverse agonist, attenuates aspects of nicotine withdrawal but not reward in mice. |
2024-04-27 |
2024-04-30 |
mouse |
| Belle Buzzi, Shakir D AlSharari, David M Walentiny, M Imad Dama. Nelotanserin, a selective 5-HT2A receptor inverse agonist, attenuates aspects of nicotine withdrawal but not reward in mice. Behavioural brain research. 2024-04-27. PMID:38677331. |
targeting nicotine reward and withdrawal is a basis for the majority of smoking cessation pharmacotherapies. |
2024-04-27 |
2024-04-30 |
mouse |
| Belle Buzzi, Shakir D AlSharari, David M Walentiny, M Imad Dama. Nelotanserin, a selective 5-HT2A receptor inverse agonist, attenuates aspects of nicotine withdrawal but not reward in mice. Behavioural brain research. 2024-04-27. PMID:38677331. |
due to the emergence of interest in 5-ht2a receptor modulators for numerous psychiatric disorders, we investigated the effect of nelotanserin, a 5-ht2a receptor inverse agonist, on nicotine reward and withdrawal in icr mice. |
2024-04-27 |
2024-04-30 |
mouse |
| Belle Buzzi, Shakir D AlSharari, David M Walentiny, M Imad Dama. Nelotanserin, a selective 5-HT2A receptor inverse agonist, attenuates aspects of nicotine withdrawal but not reward in mice. Behavioural brain research. 2024-04-27. PMID:38677331. |
however, nelotanserin had no effect on anxiety-like behavior and failed to reduce nicotine reward as measured in the conditioned place preference test. |
2024-04-27 |
2024-04-30 |
mouse |
| Lois S Akinola, Jada Gonzales, Belle Buzzi, Hunter L Mathews, Roger L Papke, Jerry A Stitzel, M Imad Dama. Investigating the role of nicotinic acetylcholine receptors in menthol's effects in mice. Drug and alcohol dependence. vol 257. 2024-03-16. PMID:38492255. |
nicotinic subunits, such as β2 and α5, are of interest due to their implications in nicotine reward, reinforcement, intake regulation, and aversion. |
2024-03-16 |
2024-03-19 |
mouse |
| Brandon J Henderson, Samuel Tetteh-Quarshie, Nathan A Olszewsk. Modulators of nicotine reward and reinforcement. Advances in pharmacology (San Diego, Calif.). vol 99. 2024-03-11. PMID:38467487. |
modulators of nicotine reward and reinforcement. |
2024-03-11 |
2024-03-14 |
Not clear |
| Xinyu Wang, Yun Chen, Jing Dong, Jing Ge, Xiaoliu Liu, Jianfeng Li. Neurobiology of Stress-Induced Nicotine Relapse. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38338760. |
further investigation on the neurobiology of stress-induced nicotine relapse will shed light on the development of new medicines for controlling smoking and will help us understand the interactions between the stress and reward systems in the brain. |
2024-02-10 |
2024-02-12 |
Not clear |
| Mohit Kumar, Jack Keady, Surya P Aryal, Marissa Hessing, Christopher I Richards, Jill R Turne. The Role of Microglia in Sex- and Region-Specific Blood-Brain Barrier Integrity During Nicotine Withdrawal. Biological psychiatry global open science. vol 4. issue 1. 2024-02-01. PMID:38298802. |
microglia activation and proinflammatory neuroimmune signaling in reward neurocircuitry are implicated in nicotine withdrawal symptomology. |
2024-02-01 |
2024-02-03 |
Not clear |
| Maria Paula Faillace, Joaquin Ortiz, Leandro Rocco, Ramon Bernabe. Histone Methyltransferase G9a Plays an Essential Role on Nicotine Preference in Zebrafish. Molecular neurobiology. 2024-01-30. PMID:38289455. |
we observed a dual effect of the inhibitor bix: at high doses inhibited while at low doses potentiated nicotine reward. |
2024-01-30 |
2024-02-01 |
zebrafish |
| Maria Paula Faillace, Joaquin Ortiz, Leandro Rocco, Ramon Bernabe. Histone Methyltransferase G9a Plays an Essential Role on Nicotine Preference in Zebrafish. Molecular neurobiology. 2024-01-30. PMID:38289455. |
changes in relative levels of these mrna molecules reflected the effects of bix on nicotine reward. |
2024-01-30 |
2024-02-01 |
zebrafish |
| Maria Paula Faillace, Joaquin Ortiz, Leandro Rocco, Ramon Bernabe. Histone Methyltransferase G9a Plays an Essential Role on Nicotine Preference in Zebrafish. Molecular neurobiology. 2024-01-30. PMID:38289455. |
dimethylation of k9 at h3 is an important epigenetic modification that should be considered as a potential therapeutic target to treat nicotine reward and perhaps other drug addictions. |
2024-01-30 |
2024-02-01 |
zebrafish |
| Sydney D Houser, Kathleen R McNealy, Scott T Barrett, Rick A Bevin. Varenicline but not cotinine increased the value of a visual stimulus reinforcer in rats: No evidence for synergy of the two compounds. Pharmacology, biochemistry, and behavior. 2023-12-28. PMID:38154590. |
under some circumstances, this reward enhancement maintains nicotine consumption. |
2023-12-28 |
2023-12-31 |
rat |
| Caspar Muenstermann, Kelly J Clemen. Epigenetic Mechanisms of Nicotine Dependence. Neuroscience and biobehavioral reviews. 2023-12-09. PMID:38070842. |
pharmacological manipulation of enzymes that catalyze core epigenetic modifications regulate nicotine reward and associative learning, demonstrating a functional role of epigenetic modifications in nicotine dependence. |
2023-12-09 |
2023-12-17 |
Not clear |
| Caspar Muenstermann, Kelly J Clemen. Epigenetic Mechanisms of Nicotine Dependence. Neuroscience and biobehavioral reviews. 2023-12-09. PMID:38070842. |
these findings are consistent with nicotine promoting an overall permissive chromatin state at genes important for learning, memory and reward. |
2023-12-09 |
2023-12-17 |
Not clear |
| Jude A Frie, Patrick McCunn, Amr Eed, Ahmad Hassan, Karling R Luciani, Chuyun Chen, Rachel F Tyndale, Jibran Y Khokha. Factors influencing JUUL e-cigarette nicotine vapour-induced reward, withdrawal, pharmacokinetics and brain connectivity in rats: sex matters. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-12-06. PMID:38057369. |
factors influencing juul e-cigarette nicotine vapour-induced reward, withdrawal, pharmacokinetics and brain connectivity in rats: sex matters. |
2023-12-06 |
2023-12-10 |
rat |
| Jázmin Ayman, Miklós Palotai, Roberta Dochnal, Zsolt Bagos. Ghrelin Amplifies the Nicotine-Induced Release of Dopamine in the Bed Nucleus of Stria Terminalis (BNST). Biomedicines. vol 11. issue 9. 2023-09-28. PMID:37760897. |
nicotine is the principal psychoactive component in tobacco and is responsible for the reward sensation produced by smoking. |
2023-09-28 |
2023-10-07 |
rat |