| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Amr Seifelnasr, Xiuhua April Si, Jinxiang X. Visualization and Estimation of Nasal Spray Delivery to Olfactory Mucosa in an Image-Based Transparent Nasal Model. Pharmaceutics. vol 15. issue 6. 2023-06-28. PMID:37376105. |
visualization and estimation of nasal spray delivery to olfactory mucosa in an image-based transparent nasal model. |
2023-06-28 |
2023-08-14 |
Not clear |
| John B Finlay, Ralph Abi Hachem, David W Jang, Nosayaba Osazuwa-Peters, Bradley J Goldstei. Deconstructing Olfactory Epithelium Developmental Pathways in Olfactory Neuroblastoma. Cancer research communications. vol 3. issue 6. 2023-06-28. PMID:37377616. |
olfactory neuroblastoma is a rare tumor arising from the olfactory cleft region of the nasal cavity. |
2023-06-28 |
2023-08-14 |
human |
| Mahmoud Al Aaraj, Mustafa Boorinie, Louay Salfity, Ahmed Eweis. The use of Platelet rich Plasma in COVID-19 Induced Olfactory Dysfunction: Systematic Review. Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India. 2023-06-26. PMID:37362129. |
in this review, we are looking at a novel intervention using platelet-rich plasma injection into the nasal cleft for treatment of post covid-19 infection olfactory dysfunction. |
2023-06-26 |
2023-08-14 |
Not clear |
| Tatsuya Tsukahara, David H Brann, Sandeep Robert Datt. Mechanisms of SARS-CoV-2 Associated Anosmia. Physiological reviews. 2023-06-21. PMID:37342077. |
while the sars-cov-2 virus targets the nasal olfactory epithelium, current evidence suggests that neuronal infection is extremely rare both in the olfactory periphery and the brain, prompting the need for mechanistic models that can explain that widespread anosmia in covid-19 patients. |
2023-06-21 |
2023-08-14 |
Not clear |
| Z Li, R Salloum, T Humme. Patients with olfactory loss exhibit pronounced adaptation to chemosensory stimuli: an electrophysiological study. Rhinology. 2023-06-19. PMID:37334730. |
the study aimed to investigate adaptation to olfactory and trigeminal nasal stimuli in patients with olfactory loss in comparison to controls using electrophysiological measures. |
2023-06-19 |
2023-08-14 |
Not clear |
| Hadrien Calmet, Damien Dosimont, David Oks, Guillaume Houzeaux, Brenda Vara Almirall, Kiao Inthavon. Machine learning and sensitivity analysis for predicting nasal drug delivery for targeted deposition. International journal of pharmaceutics. 2023-06-15. PMID:37321463. |
to reduce the computational costs of a full transient large eddy simulation flow field, we create a time-averaged frozen field and perform the time integration of particle trajectories through the flow field to determine the particle deposition in four anatomical regions of the nasal cavity (anterior, middle, olfactory and posterior) for each of the 384 spray field. |
2023-06-15 |
2023-08-14 |
Not clear |
| Keita Sasaki, Shota Fukakusa, Yusuke Torikai, Chie Suzuki, Ikumi Sonohata, Takuto Kawahata, Yasuhiro Magata, Keiichi Kawai, Shunji Harut. Effective nose-to-brain drug delivery using a combination system targeting the olfactory region in monkeys. Journal of controlled release : official journal of the Controlled Release Society. 2023-06-14. PMID:37315691. |
this n2b-system demonstrated a much greater formulation distribution ratio in the olfactory region in an in vitro experiment using a 3d-printed nasal cast and in vivo experiment using cynomolgus monkeys, as compared to that in other nasal drug delivery systems that comprise of a proprietary nasal powder device developed for nasal absorption and vaccination and a commercially available liquid spray. |
2023-06-14 |
2023-08-14 |
monkey |
| Xingyu Han, Xuejia He, Xiaojun Zhan, Linyin Yao, Zhifu Sun, Xing Gao, Shan Wang, Zhenlin Wan. Disturbed microbiota-metabolites-immune interaction network is associated with olfactory dysfunction in patients with chronic rhinosinusitis. Frontiers in immunology. vol 14. 2023-06-09. PMID:37292198. |
however, little information is available about the effect of the inflammation-related nasal microbiota and related metabolites on the olfactory function in these patients. |
2023-06-09 |
2023-08-14 |
Not clear |
| Naomi Oka, Kazuya Shimada, Azusa Ishii, Nobuyuki Kobayashi, Kazuhiro Kond. SARS-CoV-2 S1 protein causes brain inflammation by reducing intracerebral acetylcholine production. iScience. vol 26. issue 6. 2023-06-06. PMID:37275532. |
expressing sars-cov-2 s1 protein in the nasal cavity of mice was associated with increased apoptosis of the olfactory system and decreased intracerebral acetylcholine production. |
2023-06-06 |
2023-08-14 |
mouse |
| Raquel Taléns-Visconti, Jesus Vicente de Julián-Ortiz, Ofelia Vila-Busó, Octavio Diez-Sales, Amparo Náche. Intranasal Drug Administration in Alzheimer-Type Dementia: Towards Clinical Applications. Pharmaceutics. vol 15. issue 5. 2023-05-27. PMID:37242641. |
intranasal administration offers a direct route to the brain via the nasal cavity's olfactory and trigeminal pathways. |
2023-05-27 |
2023-08-14 |
Not clear |
| Christos Kaikousidis, Paraskevi Papakyriakopoulou, Aristides Dokoumetzidis, Georgia Valsam. Donepezil Brain and Blood Pharmacokinetic Modeling after Nasal Film and Oral Solution Administration in Mice. Pharmaceutics. vol 15. issue 5. 2023-05-27. PMID:37242651. |
the anatomic connection of the nasal cavity with the central nervous system (cns) is based on two nerves: olfactory and trigeminal. |
2023-05-27 |
2023-08-14 |
mouse |
| Dan Li, Wen-da Feng, Teng-Yu Chen, Cai-Shan Fang, Man-Qing Lin, Rui-Zhi Wang, Jin-Xiang Zhu, Xue-Cheng He, Jia-Jun Zhang, Qin-Dong Liu, WeiZhen Xu, Shun-Lan Wang, Chun-Qiao Li, Yi-Xing Zhou, Yan Ruan, Min Zho. Diagnosis and Treatment Strategy of Nasogenic Olfactory Dysfunction. International archives of allergy and immunology. vol 184. issue 6. 2023-05-26. PMID:37231897. |
it is worth emphasizing that the olfactory region in nasal cavity is recognized as the primary and critical olfactory receptor. |
2023-05-26 |
2023-08-14 |
Not clear |
| Yi Li, Hao Guo, Dongsheng Tang, Zengtao Xin, Weiyuan Yang, Ping Ya. Application of Auricular Cartilage Scaffold Combined With L-Shaped Prosthesis in Asian Rhinoplasty. The Journal of craniofacial surgery. 2023-05-23. PMID:37220717. |
at >12 months follow-up, there were no serious adverse effects on nasal ventilation and olfactory function in any of the patients. |
2023-05-23 |
2023-08-14 |
Not clear |
| Priyanka Thangaraj, Ramesh Varadharaja. Assessment of Olfactory Dysfunction Using ODOFIN Sniffin' Sticks: A Prospective Comparative Study. Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India. vol 75. issue Suppl 1. 2023-05-19. PMID:37206763. |
this study was done using sniffin stick test kit with an objective to compare the effect of steroid nasal spray with normal saline nasal spray in improving the olfactory dysfunction seen in cases of chronic nasal obstruction. |
2023-05-19 |
2023-08-14 |
human |
| Priyanka Thangaraj, Ramesh Varadharaja. Assessment of Olfactory Dysfunction Using ODOFIN Sniffin' Sticks: A Prospective Comparative Study. Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India. vol 75. issue Suppl 1. 2023-05-19. PMID:37206763. |
this prospective comparative study was conducted on patients presenting to the ent opd with olfactory dysfunction due to various nasal pathologies. |
2023-05-19 |
2023-08-14 |
human |
| Anna Kristina Hernandez, Antje Walke, Antje Haehner, Mandy Cuevas, Thomas Humme. Correlations between gustatory, trigeminal, and olfactory functions and nasal airflow. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 2023-05-02. PMID:37129608. |
correlations between gustatory, trigeminal, and olfactory functions and nasal airflow. |
2023-05-02 |
2023-08-14 |
human |
| Sarah M Russel, Harry Chiang, John B Finlay, Reanna Shah, Jeffrey R Marcus, David W Jang, Ralph Abi Hachem, Bradley J Goldstein, Dennis Onyeka Frank-It. Characterizing Olfactory Dysfunction in Patients with Unilateral Cleft Lip Nasal Deformities. Facial plastic surgery & aesthetic medicine. 2023-05-02. PMID:37130297. |
characterizing olfactory dysfunction in patients with unilateral cleft lip nasal deformities. |
2023-05-02 |
2023-08-14 |
Not clear |
| Carlo C Lazado, Marianne Iversen, Arvind Y M Sundara. Comparative basal transcriptome profiles of the olfactory rosette and gills of Atlantic salmon (Salmo salar) unveil shared and distinct immunological features. Genomics. 2023-05-01. PMID:37127252. |
the basal transcriptome of atlantic salmon olfactory rosette is a valuable molecular toolbox that will advance our understanding of nasal immunity in teleost fish. |
2023-05-01 |
2023-08-14 |
Not clear |
| Juliana Costa Dos Santos, Marjory Ximenes Rabelo, Luana Mattana Sebben, Matheus Vinicius de Souza Carneiro, João Bosco Lopes Botelho, José Cardoso Neto, Anderson Nogueira Barbosa, Diego Monteiro de Carvalho, Gemilson Soares Ponte. Persistence of SARS-CoV-2 Antigens in the Nasal Mucosa of Eight Patients with Inflammatory Rhinopathy for over 80 Days following Mild COVID-19 Diagnosis. Viruses. vol 15. issue 4. 2023-04-28. PMID:37112879. |
we evaluated eight adults without previous nasal diseases and with a history of covid-19 and persistent olfactory dysfunction for more than 80 days after diagnosis of sars-cov-2 infection. |
2023-04-28 |
2023-08-14 |
Not clear |
| Eugene Wong, Murray Smith, Malcolm A Buchanan, Akshay Kudpaje, Andrew Williamson, Prasanna Suresh Hedge, Daniel Hazan, Jordan Idaire, Mark C Smith, Niranjan Sritharan, Carsten Palme, Faruque Riffa. Smell-related quality of life changes after total laryngectomy: a multi-centre study. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 2023-04-28. PMID:37115324. |
the subsequent reduction in nasal airflow, and therefore, reduction in deposition of particles to the olfactory neuroepithelium leads to hyposmia or anosmia. |
2023-04-28 |
2023-08-14 |
Not clear |