| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jae Yong Lee, Hee Kyung Ki. Primary olfactory neuroblastoma originating from the inferior meatus of the nasal cavity. American journal of otolaryngology. vol 28. issue 3. 2007-08-23. PMID:17499140. |
olfactory neuroblastoma is a rare malignant tumor of the nasal cavity arising from the olfactory neuroepithelium. |
2007-08-23 |
2023-08-12 |
Not clear |
| Adele J Vincent, Derek L Choi-Lundberg, Julie A Harris, Adrian K West, Meng Inn Chua. Bacteria and PAMPs activate nuclear factor kappaB and Gro production in a subset of olfactory ensheathing cells and astrocytes but not in Schwann cells. Glia. vol 55. issue 9. 2007-07-25. PMID:17427933. |
the primary olfactory nerves provide uninterrupted conduits for neurotropic pathogens to access the brain from the nasal cavity, yet infection via this route is uncommon. |
2007-07-25 |
2023-08-12 |
Not clear |
| Hélène Débat, Corinne Eloit, Florence Blon, Benoît Sarazin, Céline Henry, Jean-Claude Huet, Didier Trotier, Jean-Claude Pernolle. Identification of human olfactory cleft mucus proteins using proteomic analysis. Journal of proteome research. vol 6. issue 5. 2007-07-24. PMID:17381150. |
in humans, the olfactory epithelium is located in two narrow passages, the olfactory clefts, at the upper part of the nasal cavities. |
2007-07-24 |
2023-08-12 |
human |
| S T Charlton, S S Davis, L Illu. Nasal administration of an angiotensin antagonist in the rat model: effect of bioadhesive formulations on the distribution of drugs to the systemic and central nervous systems. International journal of pharmaceutics. vol 338. issue 1-2. 2007-07-19. PMID:17337137. |
changing the depth of insertion of the cannula from 7 to 15mm, in order to reach the olfactory region in the nasal cavity significantly decreased plasma levels and significantly increased brain tissue levels of drug for the two formulations studied (1.0% pectin lm-12 and a simple drug solution). |
2007-07-19 |
2023-08-12 |
rat |
| Frans W H M Merkus, Mascha P van den Ber. Can nasal drug delivery bypass the blood-brain barrier?: questioning the direct transport theory. Drugs in R&D. vol 8. issue 3. 2007-07-13. PMID:17472409. |
the connection between the nasal cavity and the cns by the olfactory neurones has been investigated extensively during the last decades with regard to its feasibility to serve as a direct drug transport route to the csf and brain. |
2007-07-13 |
2023-08-12 |
rat |
| Angela Chalé-Rush, John R Burgess, Richard D Matte. Multiple routes of chemosensitivity to free fatty acids in humans. American journal of physiology. Gastrointestinal and liver physiology. vol 292. issue 5. 2007-07-06. PMID:17234892. |
this study examined orthonasal olfactory, retronasal olfactory, nasal irritancy, oral irritancy, gustatory, and multimodal threshold sensitivity to linoleic, oleic, and stearic acids. |
2007-07-06 |
2023-08-12 |
human |
| Philippe Rombaux, Bernard Bertrand, Thomas Keller, André Mourau. Clinical significance of olfactory event-related potentials related to orthonasal and retronasal olfactory testing. The Laryngoscope. vol 117. issue 6. 2007-07-05. PMID:17460578. |
causes of olfactory dysfunction included postinfectious olfactory loss (n = 15), head trauma (n = 26), nasal polyposis (n = 15), and mixed causes (idiopathic, toxic, drug induced) (n = 9). |
2007-07-05 |
2023-08-12 |
Not clear |
| Thomas Braun, Petra Voland, Lars Kunz, Christian Prinz, Manfred Gratz. Enterochromaffin cells of the human gut: sensors for spices and odorants. Gastroenterology. vol 132. issue 5. 2007-06-26. PMID:17484882. |
we were interested to know whether nasal olfactory receptors are also expressed in the human gut mucosa by enterochromaffin cells and whether their ligands and odorants present in spices, fragrances, detergents, and cosmetics cause serotonin release. |
2007-06-26 |
2023-08-12 |
human |
| J A Covington, J W Gardner, A Hamilton, T C Pearce, S L Ta. Towards a truly biomimetic olfactory microsystem: an artificial olfactory mucosa. IET nanobiotechnology. vol 1. issue 2. 2007-06-19. PMID:17428120. |
experimental studies on the mammalian olfactory system suggest that the nasal cavity, comprising of the mucous layer and the olfactory epithelium, performs a degree of chromatographic separation of complex mixtures. |
2007-06-19 |
2023-08-12 |
human |
| Ryosuke Mori, Haruo Sakai, Masataka Kato, Toshiro Hida, Masato Nakajima, Takahiro Fukuda, Masaharu Fukunaga, Toshiaki Ab. [Olfactory neuroblastoma with spinal metastasis: case report]. No shinkei geka. Neurological surgery. vol 35. issue 5. 2007-06-18. PMID:17491347. |
olfactory neuroblastoma is a rare tumor of the nasal cavity. |
2007-06-18 |
2023-08-12 |
Not clear |
| Geoffrey C Yang, Peter W Scherer, Kai Zhao, Maxwell M Mozel. Numerical modeling of odorant uptake in the rat nasal cavity. Chemical senses. vol 32. issue 3. 2007-06-12. PMID:17220517. |
this numerical approach is the first to predict detailed odorant flux information across the olfactory mucosa in the rat nasal cavity during inspiratory and expiratory flow and to relate it to anatomic olfactory receptor location, physiological function, and biochemical experiment. |
2007-06-12 |
2023-08-12 |
rat |
| Geoffrey C Yang, Peter W Scherer, Maxwell M Mozel. Modeling inspiratory and expiratory steady-state velocity fields in the Sprague-Dawley rat nasal cavity. Chemical senses. vol 32. issue 3. 2007-06-12. PMID:17220519. |
distribution patterns of odorant molecules in the rat nasal olfactory region depend in large part on the detailed airflow patterns in the nasal cavity, which in turn depend on the anatomical structure. |
2007-06-12 |
2023-08-12 |
rat |
| Geoffrey C Yang, Peter W Scherer, Maxwell M Mozel. Modeling inspiratory and expiratory steady-state velocity fields in the Sprague-Dawley rat nasal cavity. Chemical senses. vol 32. issue 3. 2007-06-12. PMID:17220519. |
the rat nasal velocity calculations will be used to study the distribution of odorant uptake onto the rat olfactory mucosa and compare it with the known anatomic location of some types of rat olfactory receptors. |
2007-06-12 |
2023-08-12 |
rat |
| Didier Trotier, Jean Loup Bensimon, Philippe Herman, Patrice Tran Ba Huy, Kjell B Døving, Corinne Eloi. Inflammatory obstruction of the olfactory clefts and olfactory loss in humans: a new syndrome? Chemical senses. vol 32. issue 3. 2007-06-12. PMID:17237476. |
in humans, this sensory epithelium is located at 2 narrow passages, the olfactory clefts, at the upper part of the nasal cavities. |
2007-06-12 |
2023-08-12 |
human |
| Didier Trotier, Jean Loup Bensimon, Philippe Herman, Patrice Tran Ba Huy, Kjell B Døving, Corinne Eloi. Inflammatory obstruction of the olfactory clefts and olfactory loss in humans: a new syndrome? Chemical senses. vol 32. issue 3. 2007-06-12. PMID:17237476. |
this study demonstrates that the olfactory clefts, in human, function as an entity that is different from other regions of the nasal cavity and is the target for local inflammatory events that are apparently not responding to corticoid and antibiotic treatments. |
2007-06-12 |
2023-08-12 |
human |
| S Charlton, N S Jones, S S Davis, L Illu. Distribution and clearance of bioadhesive formulations from the olfactory region in man: effect of polymer type and nasal delivery device. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. vol 30. issue 3-4. 2007-05-23. PMID:17223022. |
distribution and clearance of bioadhesive formulations from the olfactory region in man: effect of polymer type and nasal delivery device. |
2007-05-23 |
2023-08-12 |
human |
| S Charlton, N S Jones, S S Davis, L Illu. Distribution and clearance of bioadhesive formulations from the olfactory region in man: effect of polymer type and nasal delivery device. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. vol 30. issue 3-4. 2007-05-23. PMID:17223022. |
there is an increasing need to identify novel approaches by which to improve the efficiency of drug transport from the nasal cavity (olfactory region) to the cns, especially for treatment of central nervous system disorders. |
2007-05-23 |
2023-08-12 |
human |
| S Charlton, N S Jones, S S Davis, L Illu. Distribution and clearance of bioadhesive formulations from the olfactory region in man: effect of polymer type and nasal delivery device. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. vol 30. issue 3-4. 2007-05-23. PMID:17223022. |
it was found that all of the bioadhesive formulations were able to reach the olfactory region in the nasal cavity of human volunteers when delivered using a simple nasal drop device. |
2007-05-23 |
2023-08-12 |
human |
| S Charlton, N S Jones, S S Davis, L Illu. Distribution and clearance of bioadhesive formulations from the olfactory region in man: effect of polymer type and nasal delivery device. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. vol 30. issue 3-4. 2007-05-23. PMID:17223022. |
in contrast, a pectin formulation administered with a nasal spray system did not show an increase in residence time in the olfactory region. |
2007-05-23 |
2023-08-12 |
human |
| Burton Slotnick, Angelica Sanguino, Scott Husband, Gregory Marquino, Alan Silberber. Olfaction and olfactory epithelium in mice treated with zinc gluconate. The Laryngoscope. vol 117. issue 4. 2007-05-17. PMID:17415147. |
we assessed whether a nasal spray containing zinc gluconate (zg) compromises the integrity of olfactory epithelium and olfactory function. |
2007-05-17 |
2023-08-12 |
mouse |