| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Matthias van Woensel, Nathalie Wauthoz, Rémi Rosière, Karim Amighi, Véronique Mathieu, Florence Lefranc, Stefaan W van Gool, Steven de Vleeschouwe. Formulations for Intranasal Delivery of Pharmacological Agents to Combat Brain Disease: A New Opportunity to Tackle GBM? Cancers. vol 5. issue 3. 2013-11-08. PMID:24202332. |
upon presentation at the nasal cavity, pharmacological agents reach the brain via the olfactory and trigeminal nerves. |
2013-11-08 |
2023-08-12 |
Not clear |
| Andrew Toft, Mercedes Tome, Susan C Barnett, John S Riddel. A comparative study of glial and non-neural cell properties for transplant-mediated repair of the injured spinal cord. Glia. vol 61. issue 4. 2013-10-28. PMID:23322541. |
transplants included: (i) purified olfactory ensheathing cells (oecs) and (ii) fibroblast-like cells, from olfactory bulb (obfb-l), (iii) a 50:50 mixture of (i) and (ii) (oec/obfb-l), (iv) dissociated nasal mucosa (om), (v) purified peripheral nerve schwann cells (scs), (vi) peripheral nerve fibroblasts, and (vii) skin fibroblasts (sf). |
2013-10-28 |
2023-08-12 |
rat |
| Naoto Yoshino, Masahiro Endo, Hiroyuki Kanno, Naomi Matsukawa, Reiko Tsutsumi, Ryosuke Takeshita, Shigehiro Sat. Polymyxins as novel and safe mucosal adjuvants to induce humoral immune responses in mice. PloS one. vol 8. issue 4. 2013-10-17. PMID:23593492. |
moreover, mice intranasally immunized with ova plus various doses of pmb or cl showed neither inflammatory responses in the nasal cavity and olfactory bulbs nor renal damages, compared to those given ova alone. |
2013-10-17 |
2023-08-12 |
mouse |
| Boo-Young Kim, Hye Lim Son, Seok-Gu Kang, Sung Won Kim, Yong Kil Hong, Sin-Soo Jeun, Soo Whan Kim, Jin Hee Cho, Yong Jin Par. Postoperative nasal symptoms associated with an endoscopic endonasal transsphenoidal approach. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 270. issue 4. 2013-09-30. PMID:23081674. |
however, rhinologists must consider postoperative nasal symptoms and perform a proper preoperative examination, especially with regard to the olfactory function, and inform patients scheduled for eetsa of potential postoperative changes. |
2013-09-30 |
2023-08-12 |
Not clear |
| Yoshihito Niimur. Identification of olfactory receptor genes from mammalian genome sequences. Methods in molecular biology (Clifton, N.J.). vol 1003. 2013-09-30. PMID:23585032. |
diverse odorant molecules in the environment are detected by olfactory receptors (ors) expressed in the olfactory epithelium of the nasal cavity. |
2013-09-30 |
2023-08-12 |
Not clear |
| Dae Woo Kim, Jin-Yong Kim, Sang-Wook Kim, Sea-Yuong Jeo. Postoperative olfactory results in chronic rhinosinusitis with nasal polyposis according to wound healing status. Clinical and experimental otorhinolaryngology. vol 6. issue 3. 2013-09-26. PMID:24069517. |
postoperative olfactory results in chronic rhinosinusitis with nasal polyposis according to wound healing status. |
2013-09-26 |
2023-08-12 |
Not clear |
| Chandrakantsing Vijaysing Pardeshi, Veena Shailendra Belgamwa. Direct nose to brain drug delivery via integrated nerve pathways bypassing the blood-brain barrier: an excellent platform for brain targeting. Expert opinion on drug delivery. vol 10. issue 7. 2013-09-10. PMID:23586809. |
these nerve pathways initiate in the nasal cavity at olfactory neuroepithelium and terminate in the brain. |
2013-09-10 |
2023-08-12 |
Not clear |
| Xiuhua A Si, Jinxiang Xi, Jongwon Kim, Yue Zhou, Hualiang Zhon. Modeling of release position and ventilation effects on olfactory aerosol drug delivery. Respiratory physiology & neurobiology. vol 186. issue 1. 2013-09-06. PMID:23313127. |
the objective of this study is to numerically evaluate two olfactory delivery protocols in a mri-based nasal airway model: (1) pointed drug release in the vestibule (i.e., vestibular intubation), and (2) deep intubation with mediation released close to the olfactory mucosa. |
2013-09-06 |
2023-08-12 |
Not clear |
| Mitsunari Nakajima, Momoko Tsuruta, Hisamichi Mori, Chisa Nishikawa, Satoshi Okuyama, Yoshiko Furukaw. A comparative study of axon-surrounding cells in the two nasal nerve tracts from mouse olfactory epithelium and vomeronasal organ. Brain research. vol 1503. 2013-09-05. PMID:23410787. |
the olfactory and vomeronasal systems are the two nasal chemical detectors in mammals. |
2013-09-05 |
2023-08-12 |
mouse |
| Yong-Liang Wang, Yan Yuan, Jun Yang, Chang-Hong Wang, Yan-Juan Pan, Lu Lu, Yu-Quan Wu, Da-Xin Wang, Lu-Xian Lv, Ren-Ren Li, Lei Xue, Xin-Hua Wang, Jian-Wei Bi, Xin-Feng Liu, Yan-Ning Qian, Zhi-Kuan Deng, Zhi-Jian Zhang, Xin-Huan Zhai, Xin-Jian Zhou, Guo-Liang Wang, Jian-Xin Zhai, Wen-Yan Li. The interaction between the oxytocin and pain modulation in headache patients. Neuropeptides. vol 47. issue 2. 2013-08-30. PMID:23375440. |
the interest has been expressed in the use of the nasal route for delivery of oxt to the brain directly, exploiting the olfactory pathway. |
2013-08-30 |
2023-08-12 |
human |
| Hideaki Shiga, Junichi Taki, Kohshin Washiyama, Junpei Yamamoto, Sakae Kinase, Koichi Okuda, Seigo Kinuya, Naoto Watanabe, Hisao Tonami, Kichiro Koshida, Ryohei Amano, Mitsuru Furukawa, Takaki Miw. Assessment of olfactory nerve by SPECT-MRI image with nasal thallium-201 administration in patients with olfactory impairments in comparison to healthy volunteers. PloS one. vol 8. issue 2. 2013-08-29. PMID:23469046. |
assessment of olfactory nerve by spect-mri image with nasal thallium-201 administration in patients with olfactory impairments in comparison to healthy volunteers. |
2013-08-29 |
2023-08-12 |
human |
| Hideaki Shiga, Junichi Taki, Kohshin Washiyama, Junpei Yamamoto, Sakae Kinase, Koichi Okuda, Seigo Kinuya, Naoto Watanabe, Hisao Tonami, Kichiro Koshida, Ryohei Amano, Mitsuru Furukawa, Takaki Miw. Assessment of olfactory nerve by SPECT-MRI image with nasal thallium-201 administration in patients with olfactory impairments in comparison to healthy volunteers. PloS one. vol 8. issue 2. 2013-08-29. PMID:23469046. |
the aim of this study was to assess whether migration of thallium-201 ((201)tl) to the olfactory bulb were reduced in patients with olfactory impairments in comparison to healthy volunteers after nasal administration of (201)tl. |
2013-08-29 |
2023-08-12 |
human |
| G Fyrmpas, M Tsalighopoulos, J Constantinidi. Lateralized olfactory difference in patients with a nasal septal deviation before and after septoplasty*. Hippokratia. vol 16. issue 2. 2013-08-12. PMID:23935274. |
lateralized olfactory difference in patients with a nasal septal deviation before and after septoplasty*. |
2013-08-12 |
2023-08-12 |
Not clear |
| G Fyrmpas, M Tsalighopoulos, J Constantinidi. Lateralized olfactory difference in patients with a nasal septal deviation before and after septoplasty*. Hippokratia. vol 16. issue 2. 2013-08-12. PMID:23935274. |
higher olfactory thresholds are correlated with the obstructed side of a nasal septal deviation (nsd). |
2013-08-12 |
2023-08-12 |
Not clear |
| Diana Gomez, Jose A Martinez, Leah R Hanson, William H Frey, Cory C Tot. Intranasal treatment of neurodegenerative diseases and stroke. Frontiers in bioscience (Scholar edition). vol 4. 2013-08-05. PMID:22202044. |
we will review current understanding of the mechanisms underlying intranasal delivery to the cns, along with discussion of pathways permitting entry from the nasal cavity into the cns, particularly those involving the olfactory and trigeminal nerves. |
2013-08-05 |
2023-08-12 |
Not clear |
| Yi-Yun Kao, Tsun-Jen Cheng, De-Ming Yang, Chin-Tien Wang, Yin-Mei Chiung, Pei-Shan Li. Demonstration of an olfactory bulb-brain translocation pathway for ZnO nanoparticles in rodent cells in vitro and in vivo. Journal of molecular neuroscience : MN. vol 48. issue 2. 2013-08-05. PMID:22528453. |
following in vivo nasal exposure of rats to airborne zno-nps, olfactory bulbs and brains that were examined by newport-green fluorescence and tem particle measurement clearly showed the presence of zno-nps in brain. |
2013-08-05 |
2023-08-12 |
human |
| Therese Fark, Thomas Humme. Olfactory disorders: distribution according to age and gender in 3,400 patients. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 270. issue 2. 2013-08-01. PMID:22821553. |
aim of this investigation was to determine the distribution of gender and age with regard to major causes of olfactory loss, (1) trauma, (2) acute upper respiratory tract infections [uri], (3) sinunasal causes like sinusitis or nasal polyposis and (4) idiopathic. |
2013-08-01 |
2023-08-12 |
Not clear |
| Wolfgang Hanke, Katharina Mamasuew, Martin Biel, Ruey-Bing Yang, Joerg Fleische. Odorant-evoked electrical responses in Grueneberg ganglion neurons rely on cGMP-associated signaling proteins. Neuroscience letters. vol 539. 2013-07-31. PMID:23384572. |
the grueneberg ganglion (gg) in the anterior nasal region of mice is considered as an olfactory compartment since its neurons were recently observed to be activated by chemical stimuli, in particular by the odorant 2,3-dimethylpyrazine (2,3-dmp). |
2013-07-31 |
2023-08-12 |
mouse |
| P Panni, I A Ferguson, I Beacham, A Mackay-Sim, J A K Ekberg, J A St Joh. Phagocytosis of bacteria by olfactory ensheathing cells and Schwann cells. Neuroscience letters. vol 539. 2013-07-31. PMID:23415759. |
opportunistic bacterial infections of the nasal cavity could potentially lead to infection of the brain if the olfactory or trigeminal nerves are colonised. |
2013-07-31 |
2023-08-12 |
mouse |
| P Panni, I A Ferguson, I Beacham, A Mackay-Sim, J A K Ekberg, J A St Joh. Phagocytosis of bacteria by olfactory ensheathing cells and Schwann cells. Neuroscience letters. vol 539. 2013-07-31. PMID:23415759. |
as the nasal cavity is frequently exposed to bacterial infections, we hypothesised that the olfactory and trigeminal nerves within the nasal cavity could be subjected to bacterial colonisation and that the olfactory ensheathing cells and schwann cells may be involved in responding to the bacterial invasion. |
2013-07-31 |
2023-08-12 |
mouse |