| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Erkan Yildiz, Selcen Koca Yildiz, Selçuk Kuzu, Çağlar Günebakan, Abdulkadir Bucak, Orhan Kemal Kahvec. Comparison of the Healing Effect of Nasal Saline Irrigation with Triamcinolone Acetonide Versus Nasal Saline Irrigation alone in COVID-19 Related Olfactory Dysfunction: A Randomized Controlled Study. Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India. 2021-07-20. PMID:34277384. |
comparison of the healing effect of nasal saline irrigation with triamcinolone acetonide versus nasal saline irrigation alone in covid-19 related olfactory dysfunction: a randomized controlled study. |
2021-07-20 |
2023-08-13 |
Not clear |
| Erkan Yildiz, Selcen Koca Yildiz, Selçuk Kuzu, Çağlar Günebakan, Abdulkadir Bucak, Orhan Kemal Kahvec. Comparison of the Healing Effect of Nasal Saline Irrigation with Triamcinolone Acetonide Versus Nasal Saline Irrigation alone in COVID-19 Related Olfactory Dysfunction: A Randomized Controlled Study. Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India. 2021-07-20. PMID:34277384. |
saline irrigation and nasal corticosteroid treatments are safe and inexpensive methods, and have low side effects. in our study, we argue that saline nasal irrigation and topical corticosteroid treatment can be used in the treatment of patients with olfactory loss in all areas of rhinology. |
2021-07-20 |
2023-08-13 |
Not clear |
| Dafna G Milk, Grace C Khong, Osman H Çam, Fernando Alfaro-Iraheta, Claire Tierney, Firas Kassem, Samuel C Leon. A Comparison between Mygind and Kaiteki positions in administration of drops to the olfactory cleft. Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery. vol 46. issue 2. 2021-07-19. PMID:33326692. |
topical nasal steroids are a common treatment intervention for olfactory dysfunction. |
2021-07-19 |
2023-08-13 |
Not clear |
| Dafna G Milk, Grace C Khong, Osman H Çam, Fernando Alfaro-Iraheta, Claire Tierney, Firas Kassem, Samuel C Leon. A Comparison between Mygind and Kaiteki positions in administration of drops to the olfactory cleft. Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery. vol 46. issue 2. 2021-07-19. PMID:33326692. |
penetration of topical treatment to the olfactory cleft (oc), such as nasal drops, is greatly dependent on the position of the head when the treatment is administered. |
2021-07-19 |
2023-08-13 |
Not clear |
| Shigenori Inagaki, Ryo Iwata, Takeshi Ima. Bio-protocol. vol 11. issue 12. 2021-07-16. PMID:34262998. |
in the olfactory system, odorants inhaled into the nasal cavity are detected by ~1,000 types of odorant receptors (ors) that are expressed by olfactory sensory neurons (osns). |
2021-07-16 |
2023-08-13 |
mouse |
| Katie E Smith, Katherine Whitcroft, Stuart Law, Peter Andrews, David Choi, Daniel J Jagge. Olfactory ensheathing cells from the nasal mucosa and olfactory bulb have distinct membrane properties. Journal of neuroscience research. vol 98. issue 5. 2021-07-14. PMID:31797433. |
olfactory ensheathing cells from the nasal mucosa and olfactory bulb have distinct membrane properties. |
2021-07-14 |
2023-08-13 |
human |
| Devin A Boyles, Madeline M Schwarz, Joseph R Albe, Cynthia M McMillen, Katherine J O'Malley, Douglas S Reed, Amy L Hartma. Development of Rift valley fever encephalitis in rats is mediated by early infection of olfactory epithelium and neuroinvasion across the cribriform plate. The Journal of general virology. vol 102. issue 2. 2021-07-14. PMID:33231535. |
here, we visualized the entire nasal olfactory route from snout to brain after rvfv infection using rna |
2021-07-14 |
2023-08-13 |
rat |
| Laura Nižić Nodilo, Ivo Ugrina, Drago Špoljarić, Daniela Amidžić Klarić, Cvijeta Jakobušić Brala, Mirna Perkušić, Ivan Pepić, Jasmina Lovrić, Vesna Saršon, Maša Safundžić Kučuk, Dijana Zadravec, Livije Kalogjera, Anita Hafne. A Dry Powder Platform for Nose-to-Brain Delivery of Dexamethasone: Formulation Development and Nasal Deposition Studies. Pharmaceutics. vol 13. issue 6. 2021-07-14. PMID:34073500. |
nasal route of administration offers a unique opportunity of brain targeted drug delivery via olfactory and trigeminal pathway, providing effective cns concentrations at lower doses and lower risk for adverse reactions compared to systemic drug administration. |
2021-07-14 |
2023-08-13 |
Not clear |
| Laura Nižić Nodilo, Ivo Ugrina, Drago Špoljarić, Daniela Amidžić Klarić, Cvijeta Jakobušić Brala, Mirna Perkušić, Ivan Pepić, Jasmina Lovrić, Vesna Saršon, Maša Safundžić Kučuk, Dijana Zadravec, Livije Kalogjera, Anita Hafne. A Dry Powder Platform for Nose-to-Brain Delivery of Dexamethasone: Formulation Development and Nasal Deposition Studies. Pharmaceutics. vol 13. issue 6. 2021-07-14. PMID:34073500. |
the observed impact of nasal cavity asymmetry highlighted the importance of individual approach when aiming olfactory region. |
2021-07-14 |
2023-08-13 |
Not clear |
| Sven Saussez, Luigi Angelo Vaira, Carlos M Chiesa-Estomba, Serge-D Le Bon, Mihaela Horoi, Giovanna Deiana, Marzia Petrocelli, Philippe Boelpaep, Giovanni Salzano, Mohamad Khalife, Stephane Hans, Giacomo De Riu, Claire Hopkins, Jerome R Lechie. Short-Term Efficacy and Safety of Oral and Nasal Corticosteroids in COVID-19 Patients with Olfactory Dysfunction: A European Multicenter Study. Pathogens (Basel, Switzerland). vol 10. issue 6. 2021-07-14. PMID:34199734. |
short-term efficacy and safety of oral and nasal corticosteroids in covid-19 patients with olfactory dysfunction: a european multicenter study. |
2021-07-14 |
2023-08-13 |
Not clear |
| Xiuhua April Si, Muhammad Sami, Jinxiang X. Liquid Film Translocation Significantly Enhances Nasal Spray Delivery to Olfactory Region: A Numerical Simulation Study. Pharmaceutics. vol 13. issue 6. 2021-07-14. PMID:34207109. |
liquid film translocation significantly enhances nasal spray delivery to olfactory region: a numerical simulation study. |
2021-07-14 |
2023-08-13 |
Not clear |
| Xiuhua April Si, Muhammad Sami, Jinxiang X. Liquid Film Translocation Significantly Enhances Nasal Spray Delivery to Olfactory Region: A Numerical Simulation Study. Pharmaceutics. vol 13. issue 6. 2021-07-14. PMID:34207109. |
previous in vivo and ex vivo studies have tested nasal sprays with varying head positions to enhance the olfactory delivery; however, such studies often suffered from a lack of quantitative dosimetry in the target region, which relied on the observer's subjective perception of color changes in the endoscopy images. |
2021-07-14 |
2023-08-13 |
Not clear |
| Xiuhua April Si, Muhammad Sami, Jinxiang X. Liquid Film Translocation Significantly Enhances Nasal Spray Delivery to Olfactory Region: A Numerical Simulation Study. Pharmaceutics. vol 13. issue 6. 2021-07-14. PMID:34207109. |
the objective of this study is to test the feasibility of gravitationally driven droplet translocation numerically to enhance the nasal spray dosages in the olfactory region and quantify the intranasal dose distribution in the regions of interest. |
2021-07-14 |
2023-08-13 |
Not clear |
| Xiuhua April Si, Muhammad Sami, Jinxiang X. Liquid Film Translocation Significantly Enhances Nasal Spray Delivery to Olfactory Region: A Numerical Simulation Study. Pharmaceutics. vol 13. issue 6. 2021-07-14. PMID:34207109. |
for the given nasal cavity with a vertex-to-floor head position, a plume angle of 10° with a device orientation of 45° to the nostril delivered the optimal dose to the olfactory region. |
2021-07-14 |
2023-08-13 |
Not clear |
| Timothy D Smith, Alexander C Ufelle, James J Cray, Susan B Rehorek, Valerie B DeLeo. Inward collapse of the nasal cavity: Perinatal consolidation of the midface and cranial base in primates. Anatomical record (Hoboken, N.J. : 2007). vol 304. issue 5. 2021-07-13. PMID:33040450. |
here we describe the ontogeny of the posterior end of the primate cartilaginous nasal capsule, the thimble shaped posterior nasal cupula (pnc), which surrounds the hind end of the olfactory region. |
2021-07-13 |
2023-08-13 |
Not clear |
| Smrithi Padmakumar, Gregory Jones, Grishma Pawar, Olga Khorkova, Jane Hsiao, Jonghan Kim, Mansoor M Amiji, Benjamin S Bleie. Minimally Invasive Nasal Depot (MIND) technique for direct BDNF AntagoNAT delivery to the brain. Journal of controlled release : official journal of the Controlled Release Society. vol 331. 2021-07-07. PMID:33484777. |
this study describes the minimally invasive nasal depot (mind) technique, a novel method of direct trans-nasal cns drug delivery which overcomes the dosing variability and efficiency challenges of traditional topical trans-nasal, trans-olfactory strategies by delivering the entire therapeutic dose directly to the olfactory submucosal space. |
2021-07-07 |
2023-08-13 |
Not clear |
| Andre J Burnham, Phillip A Burnham, Edwin M Horwit. Survival Associations between Patient Age and Treatment Modality in Olfactory Neuroblastoma: A Retrospective Population-Based Study. Journal of clinical medicine. vol 10. issue 12. 2021-07-05. PMID:34207118. |
olfactory neuroblastoma (onb) is a rare neuroepithelial-derived malignancy that usually presents in the nasal cavity. |
2021-07-05 |
2023-08-13 |
Not clear |
| William K Boyes, Christoph van Thrie. Neurotoxicology of Nanomaterials. Chemical research in toxicology. vol 33. issue 5. 2021-07-02. PMID:32233399. |
several lines of evidence led to concerns for neurotoxicity, but perhaps none more than observations that inhaled nanoparticles impinging on the mucosal surface of the nasal epithelium could be internalized into olfactory receptor neurons and transported by axoplasmic transport into the olfactory bulbs without crossing the blood-brain barrier. |
2021-07-02 |
2023-08-13 |
human |
| Anju Sharma, Rajnish Kumar, Rahul Semwal, Imlimaong Aier, Pankaj Tyagi, Pritish Varadwa. DeepOlf: Deep neural network based architecture for predicting odorants and their interacting Olfactory Receptors. IEEE/ACM transactions on computational biology and bioinformatics. vol PP. 2021-07-01. PMID:32750862. |
olfaction transduction mechanism is triggered by the binding of odorants to the specific olfactory receptors (or's) present in the nasal cavity. |
2021-07-01 |
2023-08-13 |
Not clear |
| Marine Brulé, Margot Glaz, Christine Belloir, Nicolas Poirier, Lucie Moitrier, Fabrice Neiers, Loïc Brian. Bacterial expression and purification of vertebrate odorant-binding proteins. Methods in enzymology. vol 642. 2021-06-23. PMID:32828250. |
although their physiological role is not clearly understood, obps are proposed to carry airborne odorants toward membrane olfactory receptors through the nasal mucus. |
2021-06-23 |
2023-08-13 |
Not clear |