| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shigeki Moriguchi, Ryo Inagaki, Kohji Fukunag. Memantine improves cognitive deficits via K Molecular and cellular neurosciences. vol 117. 2021-11-30. PMID:34715352. |
olfactory bulbectomy (obx) in mice elicits cognitive deficits, and reduces cholinergic activity in the hippocampus. |
2021-11-30 |
2023-08-13 |
mouse |
| Frank Maigler, Simone Ladel, Johannes Flamm, Stella Gänger, Barbara Kurpiers, Stefanie Kiderlen, Ronja Völk, Carmen Hamp, Sunniva Hartung, Sebastian Spiegel, Arghavan Soleimanizadeh, Katharina Eberle, Rebecca Hermann, Lukas Krainer, Claudia Pitzer, Katharina Schindowsk. Selective CNS Targeting and Distribution with a Refined Region-Specific Intranasal Delivery Technique via the Olfactory Mucosa. Pharmaceutics. vol 13. issue 11. 2021-11-30. PMID:34834319. |
this study successfully demonstrated region-specific administration at the olfactory mucosa resulting in over 20% of the administered fluorescein dose in the olfactory bulbs, and no peripheral bioactivity of insulin detemir and fc-dependent uptake of two murine igg1 (11c7 and p3x) along the olfactory pathway to cortex and hippocampus. |
2021-11-30 |
2023-08-13 |
mouse |
| Guangyu Zhou, Jonas K Olofsson, Mohamad Z Koubeissi, Georgios Menelaou, Joshua Rosenow, Stephan U Schuele, Pengfei Xu, Joel L Voss, Gregory Lane, Christina Zelan. Human hippocampal connectivity is stronger in olfaction than other sensory systems. Progress in neurobiology. vol 201. 2021-11-24. PMID:33640412. |
we show that human primary olfactory cortex-including the anterior olfactory nucleus, olfactory tubercle and piriform cortex-has stronger functional connectivity with hippocampal networks at rest, compared to other sensory systems. |
2021-11-24 |
2023-08-13 |
human |
| Franco Giarrocco, Bruno B Averbec. Organization of parietoprefrontal and temporoprefrontal networks in the macaque. Journal of neurophysiology. vol 126. issue 4. 2021-11-17. PMID:34379536. |
this organization may reflect evolutionary antecedents, in which the vertebrate pallium, which is the ancestral cortex, was defined by a ventral and lateral olfactory region and a medial hippocampal region. |
2021-11-17 |
2023-08-13 |
monkey |
| Haewon Roh, June Kang, Seong-Beom Koh, Jong Hyun Ki. Hippocampal volume is related to olfactory impairment in Parkinson's disease. Journal of neuroimaging : official journal of the American Society of Neuroimaging. vol 31. issue 6. 2021-11-11. PMID:34355455. |
hippocampal volume is related to olfactory impairment in parkinson's disease. |
2021-11-11 |
2023-08-13 |
Not clear |
| Haewon Roh, June Kang, Seong-Beom Koh, Jong Hyun Ki. Hippocampal volume is related to olfactory impairment in Parkinson's disease. Journal of neuroimaging : official journal of the American Society of Neuroimaging. vol 31. issue 6. 2021-11-11. PMID:34355455. |
furthermore, the hippocampus has been regarded as a critical structure linking olfactory impairment and cognitive impairment in pd patients. |
2021-11-11 |
2023-08-13 |
Not clear |
| Haewon Roh, June Kang, Seong-Beom Koh, Jong Hyun Ki. Hippocampal volume is related to olfactory impairment in Parkinson's disease. Journal of neuroimaging : official journal of the American Society of Neuroimaging. vol 31. issue 6. 2021-11-11. PMID:34355455. |
this study aimed to identify significant structural alterations of the hippocampus in pd patients with hyposmia, and to determine whether these structural changes are significantly associated with olfactory impairment severity. |
2021-11-11 |
2023-08-13 |
Not clear |
| Ming-Wan Su, Jing-Nian Ni, Tian-Yu Cao, Shuo-Shi Wang, Jing Shi, Jin-Zhou Tia. The Correlation Between Olfactory Test and Hippocampal Volume in Alzheimer's Disease and Mild Cognitive Impairment Patients: A Meta-Analysis. Frontiers in aging neuroscience. vol 13. 2021-11-10. PMID:34744696. |
the correlation between olfactory test and hippocampal volume in alzheimer's disease and mild cognitive impairment patients: a meta-analysis. |
2021-11-10 |
2023-08-13 |
Not clear |
| Alessandro Weiss, Davide Tiziano Di Carlo, Paolo Di Russo, Francesco Weiss, Maura Castagna, Mirco Cosottini, Paolo Perrin. Microsurgical anatomy of the amygdaloid body and its connections. Brain structure & function. vol 226. issue 3. 2021-11-02. PMID:33528620. |
furthermore, the amygdaloid body is connected with the hippocampus through the amygdalo-hippocampal bundle, with the anterolateral temporal cortex through the amygdalo-temporalis fascicle, the anterior commissure and the temporo-pulvinar bundle of arnold, with the insular cortex through the lateral olfactory stria, with the ambiens gyrus, the para-hippocampal gyrus and the basal forebrain through the cingulum, and with the frontal cortex through the uncinate fascicle. |
2021-11-02 |
2023-08-13 |
human |
| Praveen Kulkarni, Nicole Bens, Dhruv K Karia, Craig F Ferri. Whole brain in vivo neuropathology: Imaging site-specific changes in brain structure over time following trimethyltin exposure in rats. Toxicology letters. vol 352. 2021-10-29. PMID:34600096. |
at 7 days the level of injury expanded to include most of the cerebral cortex, hippocampus, olfactory system, and cerebellum/brainstem corroborating much of the work done with traditional histopathology. |
2021-10-29 |
2023-08-13 |
rat |
| Fumiko Obata, Tom Obri. Distribution of Gb(3) Immunoreactivity in the Mouse Central Nervous System. Toxins. vol 2. issue 8. 2021-10-20. PMID:20725533. |
the immunoreactive neurons are in olfactory bulbs, cerebral cortex, hippocampus, striatum, amygdala, thalamus, hypothalamus, cerebellum, and medulla oblongata. |
2021-10-20 |
2023-08-12 |
mouse |
| Alvaro Duque, Jon I Arellano, Pasko Raki. An assessment of the existence of adult neurogenesis in humans and value of its rodent models for neuropsychiatric diseases. Molecular psychiatry. 2021-10-20. PMID:34667259. |
this capacity diminishes considerably in birds and even more in mammals where it persists only in the olfactory system and hippocampal dentate gyrus. |
2021-10-20 |
2023-08-13 |
human |
| Santiago Bianconi, María Belén Poretti, Paula Rodríguez, Giulia Maestri, Pamela Elizabeth Rodríguez, Susana Rubiales de Barioglio, Helgi B Schiöth, Valeria Paola Carlin. Ghrelin restores memory impairment following olfactory bulbectomy in mice by activating hippocampal NMDA1 and MAPK1 gene expression. Behavioural brain research. vol 410. 2021-10-18. PMID:33964353. |
ghrelin restores memory impairment following olfactory bulbectomy in mice by activating hippocampal nmda1 and mapk1 gene expression. |
2021-10-18 |
2023-08-13 |
mouse |
| Wei Han, Mingxing Gao, Changqing Xie, Jinhua Zhang, Zikai Zhao, Xueying Hu, Wanpo Zhang, Xiaoli Liu, Shengbo Cao, Guofu Cheng, Changqin G. Precise localization and dynamic distribution of Japanese encephalitis virus in the rain nuclei of infected mice. PLoS neglected tropical diseases. vol 15. issue 6. 2021-10-18. PMID:34153060. |
the expression of the viral antigen in the hippocampal ca2 region, the anterior olfactory nucleus, and the deep mesencephalic nucleus was high and persistent. |
2021-10-18 |
2023-08-13 |
mouse |
| Ito Kawakami, Atsuko Motoda, Masashi Hashimoto, Aki Shimozawa, Masami Masuda-Suzukake, Reiko Ohtani, Mina Takase, Mari Kumashiro, Kazuyuki Samejima, Masato Hasegaw. Progression of phosphorylated α-synuclein in Macaca fuscata. Brain pathology (Zurich, Switzerland). vol 31. issue 5. 2021-10-13. PMID:33754430. |
the left hemisphere, including parietal/temporal cortex presented sparse α-syn pathology, and no immunoreactivity was seen in olfactory nerves, amygdala, hippocampus, or right parietal/temporal cortex. |
2021-10-13 |
2023-08-13 |
human |
| Jacopo Pasquini, David J Brooks, Nicola Paves. The Cholinergic Brain in Parkinson's Disease. Movement disorders clinical practice. vol 8. issue 7. 2021-10-12. PMID:34631936. |
olfactory impairment is associated with cholinergic denervation of the limbic archicortex, specifically hippocampus and amygdala. |
2021-10-12 |
2023-08-13 |
human |
| Anshul Srivastava, Serguei Liachenko, Sumit Sarkar, Merle Paule, Natalya Sadovova, Joseph P Hani. Global Neurotoxicity: Quantitative Analysis of Rat Brain Toxicity Following Exposure to Trimethyltin. International journal of toxicology. vol 40. issue 4. 2021-10-11. PMID:33878910. |
trimethyltin toxicity was greatest in the hippocampus, olfactory area, cerebellum, pons, mammillary nucleus, inferior and superior colliculus, hypoglossal nucleus, thalamus, and cerebellar purkinje cells. |
2021-10-11 |
2023-08-13 |
rat |
| Gabriele Gerlach, Mario F Wulliman. Neural pathways of olfactory kin imprinting and kin recognition in zebrafish. Cell and tissue research. vol 383. issue 1. 2021-09-16. PMID:33515290. |
kin recognition based on olfactory and visual imprinting requires neuronal circuits that were assumed to be necessarily dependent on the interaction of mammalian amygdala, hippocampus, and isocortex, the latter being a structure that teleost fish are lacking. |
2021-09-16 |
2023-08-13 |
zebrafish |
| Li-Na Zhang, Meng-Jie Li, Ying-Hui Shang, Fan-Fan Zhao, Han-Chang Huang, Feng-Xue La. Independent and Correlated Role of Apolipoprotein E ɛ4 Genotype and Herpes Simplex Virus Type 1 in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 77. issue 1. 2021-09-08. PMID:32804091. |
hsv-1 enters host cells and can infect the olfactory system, trigeminal ganglia, entorhinal cortex, and hippocampus, and may cause ad-like pathological changes. |
2021-09-08 |
2023-08-13 |
human |
| Dimitrii S Vasilev, Nadezhda M Dubrovskaya, Igor A Zhuravin, Natalia N Nalivaev. Developmental Profile of Brain Neprilysin Expression Correlates with Olfactory Behaviour of Rats. Journal of molecular neuroscience : MN. vol 71. issue 9. 2021-09-07. PMID:33433852. |
our study demonstrates that nep mrna expression in rat olfactory bulbs (ob), entorhinal cortex (ecx), hippocampus (hip), parietal cortex (pcx) and striatum (str) increases during the first postnatal month being the highest in the ob and str. |
2021-09-07 |
2023-08-13 |
rat |