| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yan-Li Ren, Wei-Wei Chu, Xing-Wen Yang, Le Xin, Jin-Xian Gao, Gui-Zhong Yan, Can Wang, Yu-Nong Chen, Jun-Fan Xie, Karen Spruyt, Jian-Sheng Lin, Yi-Ping Hou, Yu-Feng Sha. Lavender improves sleep through olfactory perception and GABAergic neurons of the central amygdala. Journal of ethnopharmacology. 2024-10-19. PMID:39426576. |
lavender improves sleep through olfactory perception and gabaergic neurons of the central amygdala. |
2024-10-19 |
2024-10-22 |
Not clear |
| Denisa Mihalj, Stanislava Bukatova, Alexandra Reichova, Tomas Havranek, Zuzana Bacova, Barbara Szeiffova Bacova, Jan Bako. Developmental effects of oxytocin on GABAergic neurons in the olfactory brain regions. Neuroscience. 2024-08-02. PMID:39094821. |
developmental effects of oxytocin on gabaergic neurons in the olfactory brain regions. |
2024-08-02 |
2024-08-06 |
rat |
| Denisa Mihalj, Stanislava Bukatova, Alexandra Reichova, Tomas Havranek, Zuzana Bacova, Barbara Szeiffova Bacova, Jan Bako. Developmental effects of oxytocin on GABAergic neurons in the olfactory brain regions. Neuroscience. 2024-08-02. PMID:39094821. |
the present study aimed to investigate the developmental impact of oxytocin on selected parameters of the gabaergic system in olfactory brain regions. |
2024-08-02 |
2024-08-06 |
rat |
| Denisa Mihalj, Stanislava Bukatova, Alexandra Reichova, Tomas Havranek, Zuzana Bacova, Barbara Szeiffova Bacova, Jan Bako. Developmental effects of oxytocin on GABAergic neurons in the olfactory brain regions. Neuroscience. 2024-08-02. PMID:39094821. |
our data suggest that the developmental action of oxytocin in relation to the gabaergic system may represent a mechanism by which the plasticity and maturation of olfactory brain regions are regulated. |
2024-08-02 |
2024-08-06 |
rat |
| Xian-Hua Deng, Xing-Yang Liu, Yi-Hua Wei, Ke Wang, Jun-Rong Zhu, Jia-Jun Zhong, Jing-Yuan Zheng, Rui Guo, Yi-Fan Zhu, Qiu-Hong Ye, Meng-Dan Wang, Ying-Jie Chen, Jian-Quan He, Ze-Xu Chen, Shu-Qiong Huang, Chong-Shan Lv, Guo-Qing Zheng, Sui-Feng Liu, Lei We. ErbB4 deficiency exacerbates olfactory dysfunction in an early-stage Alzheimer's disease mouse model. Acta pharmacologica Sinica. 2024-07-09. PMID:38982150. |
aberrations in gabaergic function and the excitatory/inhibitory (e/i) balance within the olfactory bulb (ob) have been implicated in olfactory impairment during the initial stages of ad. |
2024-07-09 |
2024-07-12 |
mouse |
| Xian-Hua Deng, Xing-Yang Liu, Yi-Hua Wei, Ke Wang, Jun-Rong Zhu, Jia-Jun Zhong, Jing-Yuan Zheng, Rui Guo, Yi-Fan Zhu, Qiu-Hong Ye, Meng-Dan Wang, Ying-Jie Chen, Jian-Quan He, Ze-Xu Chen, Shu-Qiong Huang, Chong-Shan Lv, Guo-Qing Zheng, Sui-Feng Liu, Lei We. ErbB4 deficiency exacerbates olfactory dysfunction in an early-stage Alzheimer's disease mouse model. Acta pharmacologica Sinica. 2024-07-09. PMID:38982150. |
while the neuregulin 1 (nrg1)/erbb4 signaling pathway is known to regulate gabaergic transmission in the brain and is associated with various neuropsychiatric disorders, its specific role in early ad-related olfactory impairment remains incompletely understood. |
2024-07-09 |
2024-07-12 |
mouse |
| Xian-Hua Deng, Xing-Yang Liu, Yi-Hua Wei, Ke Wang, Jun-Rong Zhu, Jia-Jun Zhong, Jing-Yuan Zheng, Rui Guo, Yi-Fan Zhu, Qiu-Hong Ye, Meng-Dan Wang, Ying-Jie Chen, Jian-Quan He, Ze-Xu Chen, Shu-Qiong Huang, Chong-Shan Lv, Guo-Qing Zheng, Sui-Feng Liu, Lei We. ErbB4 deficiency exacerbates olfactory dysfunction in an early-stage Alzheimer's disease mouse model. Acta pharmacologica Sinica. 2024-07-09. PMID:38982150. |
further investigation revealed that deletion of erbb4 in parvalbumin interneurons reduced gabaergic transmission and increased hyperexcitability in mitral and tufted cells (m/ts) in the ob, thereby accelerating olfactory dysfunction in young adult app/ps1 mice. |
2024-07-09 |
2024-07-12 |
mouse |
| Xian-Hua Deng, Xing-Yang Liu, Yi-Hua Wei, Ke Wang, Jun-Rong Zhu, Jia-Jun Zhong, Jing-Yuan Zheng, Rui Guo, Yi-Fan Zhu, Qiu-Hong Ye, Meng-Dan Wang, Ying-Jie Chen, Jian-Quan He, Ze-Xu Chen, Shu-Qiong Huang, Chong-Shan Lv, Guo-Qing Zheng, Sui-Feng Liu, Lei We. ErbB4 deficiency exacerbates olfactory dysfunction in an early-stage Alzheimer's disease mouse model. Acta pharmacologica Sinica. 2024-07-09. PMID:38982150. |
nrg1 infusion into the ob was found to enhance gabaergic transmission in m/ts and alleviate olfactory dysfunction in young adult app/ps1 mice. |
2024-07-09 |
2024-07-12 |
mouse |
| Xian-Hua Deng, Xing-Yang Liu, Yi-Hua Wei, Ke Wang, Jun-Rong Zhu, Jia-Jun Zhong, Jing-Yuan Zheng, Rui Guo, Yi-Fan Zhu, Qiu-Hong Ye, Meng-Dan Wang, Ying-Jie Chen, Jian-Quan He, Ze-Xu Chen, Shu-Qiong Huang, Chong-Shan Lv, Guo-Qing Zheng, Sui-Feng Liu, Lei We. ErbB4 deficiency exacerbates olfactory dysfunction in an early-stage Alzheimer's disease mouse model. Acta pharmacologica Sinica. 2024-07-09. PMID:38982150. |
these findings underscore the critical role of nrg1/erbb4 signaling in regulating gabaergic transmission and e/i balance within the ob, contributing to olfactory impairment in young adult app/ps1 mice, and provide novel insights for early intervention strategies in ad. |
2024-07-09 |
2024-07-12 |
mouse |
| Xian-Hua Deng, Xing-Yang Liu, Yi-Hua Wei, Ke Wang, Jun-Rong Zhu, Jia-Jun Zhong, Jing-Yuan Zheng, Rui Guo, Yi-Fan Zhu, Qiu-Hong Ye, Meng-Dan Wang, Ying-Jie Chen, Jian-Quan He, Ze-Xu Chen, Shu-Qiong Huang, Chong-Shan Lv, Guo-Qing Zheng, Sui-Feng Liu, Lei We. ErbB4 deficiency exacerbates olfactory dysfunction in an early-stage Alzheimer's disease mouse model. Acta pharmacologica Sinica. 2024-07-09. PMID:38982150. |
this work has shown that erbb4 deficiency increased the burden of aβ, impaired gabaergic transmission, and disrupted the e/i balance of mitral and tufted cells (m/ts) in the ob, ultimately resulting in olfactory dysfunction in young adult app/ps1 mice. |
2024-07-09 |
2024-07-12 |
mouse |
| Xian-Hua Deng, Xing-Yang Liu, Yi-Hua Wei, Ke Wang, Jun-Rong Zhu, Jia-Jun Zhong, Jing-Yuan Zheng, Rui Guo, Yi-Fan Zhu, Qiu-Hong Ye, Meng-Dan Wang, Ying-Jie Chen, Jian-Quan He, Ze-Xu Chen, Shu-Qiong Huang, Chong-Shan Lv, Guo-Qing Zheng, Sui-Feng Liu, Lei We. ErbB4 deficiency exacerbates olfactory dysfunction in an early-stage Alzheimer's disease mouse model. Acta pharmacologica Sinica. 2024-07-09. PMID:38982150. |
nrg1 could enhance gabaergic transmission, rescue e/i imbalance in m/ts, and alleviate olfactory dysfunction in young adult app/ps1 mice. |
2024-07-09 |
2024-07-12 |
mouse |
| Cécilia Tremblay, Sidra Aslam, Jessica E Walker, Ileana Lorenzini, Anthony J Intorcia, Richard A Arce, Parichita Choudhury, Charles H Adler, Holly A Shill, Erika Driver-Dunckley, Shyamal Mehta, Ignazio S Piras, Christine M Belden, Alireza Atri, Thomas G Beach, Geidy E Serran. RNA sequencing of olfactory bulb in Parkinson's disease reveals gene alterations associated with olfactory dysfunction. Neurobiology of disease. 2024-04-25. PMID:38663633. |
olfactory identification test score positively correlated with expression of genes coding for g-coupled protein, glutamatergic, gabaergic, and cholinergic receptor proteins and negatively correlated with genes for proteins expressed in glial olfactory ensheathing cells. |
2024-04-25 |
2024-04-28 |
human |
| Hankui Cheng, Du Chen, Xiao Li, Umar Al-Sheikh, Duo Duan, Yuedan Fan, Linhui Zhu, Wanxin Zeng, Zhitao Hu, Xiajing Tong, Guohua Zhao, Yongming Zhang, Wenjuan Zou, Shumin Duan, Lijun Kan. Phasic/tonic glial GABA differentially transduce for olfactory adaptation and neuronal aging. Neuron. 2024-03-06. PMID:38447577. |
here, we report that the amsh glia in caenorhabditis elegans exhibit both phasic and tonic gabaergic signaling, which distinctively regulate olfactory adaptation and neuronal aging. |
2024-03-06 |
2024-03-09 |
caenorhabditis_elegans |
| Denisa Mihalj, Veronika Borbelyova, Zdeno Pirnik, Zuzana Bacova, Daniela Ostatnikova, Jan Bako. Shank3 Deficiency Results in a Reduction in GABAergic Postsynaptic Puncta in the Olfactory Brain Areas. Neurochemical research. 2024-01-06. PMID:38183586. |
shank3 deficiency results in a reduction in gabaergic postsynaptic puncta in the olfactory brain areas. |
2024-01-06 |
2024-01-09 |
Not clear |
| Denisa Mihalj, Veronika Borbelyova, Zdeno Pirnik, Zuzana Bacova, Daniela Ostatnikova, Jan Bako. Shank3 Deficiency Results in a Reduction in GABAergic Postsynaptic Puncta in the Olfactory Brain Areas. Neurochemical research. 2024-01-06. PMID:38183586. |
the specific molecular mechanism by which gabaergic transmission affects the olfactory system in asd remains unclear. |
2024-01-06 |
2024-01-09 |
Not clear |
| Denisa Mihalj, Veronika Borbelyova, Zdeno Pirnik, Zuzana Bacova, Daniela Ostatnikova, Jan Bako. Shank3 Deficiency Results in a Reduction in GABAergic Postsynaptic Puncta in the Olfactory Brain Areas. Neurochemical research. 2024-01-06. PMID:38183586. |
therefore, the present study aimed to evaluate selected components of the gabaergic system in olfactory brain regions and primary olfactory neurons isolated from shank3-deficient ( |
2024-01-06 |
2024-01-09 |
Not clear |
| Xing-Yang Liu, Ke Wang, Xian-Hua Deng, Yi-Hua Wei, Rui Guo, Sui-Feng Liu, Yi-Fan Zhu, Jia-Jun Zhong, Jing-Yuan Zheng, Meng-Dan Wang, Qiu-Hong Ye, Jian-Quan He, Kai-Hang Guo, Jun-Rong Zhu, Shu-Qiong Huang, Ze-Xu Chen, Chong-Shan Lv, Lei We. Amelioration of olfactory dysfunction in a mouse model of Parkinson's disease via enhancing GABAergic signaling. Cell & bioscience. vol 13. issue 1. 2023-06-03. PMID:37270503. |
amelioration of olfactory dysfunction in a mouse model of parkinson's disease via enhancing gabaergic signaling. |
2023-06-03 |
2023-08-14 |
mouse |
| Chelsea Hook, Adam C Puch. Bulbar projecting subcortical GABAergic neurons send collateral branches extensively and selectively to primary olfactory cortical regions. The Journal of comparative neurology. 2022-12-03. PMID:36463397. |
bulbar projecting subcortical gabaergic neurons send collateral branches extensively and selectively to primary olfactory cortical regions. |
2022-12-03 |
2023-08-14 |
Not clear |
| Chelsea Hook, Adam C Puch. Bulbar projecting subcortical GABAergic neurons send collateral branches extensively and selectively to primary olfactory cortical regions. The Journal of comparative neurology. 2022-12-03. PMID:36463397. |
this approach revealed bulbar projecting gabaergic neurons show remarkable specificity targeting other primary olfactory cortical regions exhibiting abundant collateral projections into the accessory olfactory bulb, aon, pfc, pc, and tt. |
2022-12-03 |
2023-08-14 |
Not clear |
| Chelsea Hook, Adam C Puch. Bulbar projecting subcortical GABAergic neurons send collateral branches extensively and selectively to primary olfactory cortical regions. The Journal of comparative neurology. 2022-12-03. PMID:36463397. |
we hypothesize that these olfactory gabaergic feedback neurons are a regulator of the entire olfactory system. |
2022-12-03 |
2023-08-14 |
Not clear |