| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N McNaughton, R G Morri. Buspirone produces a dose-related impairment in spatial navigation. Pharmacology, biochemistry, and behavior. vol 43. issue 1. 1992-11-02. PMID:1409800. |
buspirone affects hippocampal electrophysiology in a similar fashion to classical anxiolytics and so we predicted it would have similar effects on spatial navigation. |
1992-11-02 |
2023-08-11 |
rat |
| N McNaughton, R G Morri. Buspirone produces a dose-related impairment in spatial navigation. Pharmacology, biochemistry, and behavior. vol 43. issue 1. 1992-11-02. PMID:1409800. |
rats injected with buspirone (0.1-10.0 mg/kg, ip) showed a loss of acquisition of spatial navigation in the water maze that has a similar dose dependence to that reported for the effects of buspirone on the hippocampus. |
1992-11-02 |
2023-08-11 |
rat |
| N McNaughton, R G Morri. Buspirone produces a dose-related impairment in spatial navigation. Pharmacology, biochemistry, and behavior. vol 43. issue 1. 1992-11-02. PMID:1409800. |
this finding demonstrates that the effects of anxiolytics on spatial navigation are not due to their side effects and supports the view that changes in hippocampal function may underlie some components of clinical anxiolytic action. |
1992-11-02 |
2023-08-11 |
rat |
| M S Oitzl, E R de Kloe. Selective corticosteroid antagonists modulate specific aspects of spatial orientation learning. Behavioral neuroscience. vol 106. issue 1. 1992-05-04. PMID:1313244. |
spatial navigation is considered to be a sensitive measure for hippocampal functioning. |
1992-05-04 |
2023-08-11 |
rat |
| B F Petrie, C Pinsky, N M Standish, R Bose, G B Glavi. Parenteral domoic acid impairs spatial learning in mice. Pharmacology, biochemistry, and behavior. vol 41. issue 1. 1992-04-02. PMID:1539071. |
the results, along with neuroanatomic work done here and elsewhere, suggest that impairment of acquisition and retention of this spatial navigation task by domoic acid, involves a neuropathology that includes not only the hippocampus, but other limbic, and possibly extralimbic brain regions. |
1992-04-02 |
2023-08-11 |
mouse |
| N A Schmaju. Role of the hippocampus in temporal and spatial navigation: an adaptive neural network. Behavioural brain research. vol 39. issue 3. 1991-01-09. PMID:2244969. |
role of the hippocampus in temporal and spatial navigation: an adaptive neural network. |
1991-01-09 |
2023-08-11 |
Not clear |
| N A Schmaju. Role of the hippocampus in temporal and spatial navigation: an adaptive neural network. Behavioural brain research. vol 39. issue 3. 1991-01-09. PMID:2244969. |
these results suggest that, rather than either a temporal or spatial function, the hippocampus is involved in the computation of variables common to both temporal and spatial navigation. |
1991-01-09 |
2023-08-11 |
Not clear |
| M J Wes. Stereological studies of the hippocampus: a comparison of the hippocampal subdivisions of diverse species including hedgehogs, laboratory rodents, wild mice and men. Progress in brain research. vol 83. 1990-09-28. PMID:2203095. |
the inter-species differences are discussed in terms of neuron number and size, for which data are presented from two species, and with reference to a neural model of the cognitive map theory for hippocampal function. |
1990-09-28 |
2023-08-11 |
mouse |
| J O'Keef. A computational theory of the hippocampal cognitive map. Progress in brain research. vol 83. 1990-09-28. PMID:2203101. |
a computational theory of the hippocampal cognitive map. |
1990-09-28 |
2023-08-11 |
Not clear |
| M R Rod, I Q Whishaw, R N Aue. The relationship of structural ischemic brain damage to neurobehavioural deficit: the effect of postischemic MK-801. Canadian journal of psychology. vol 44. issue 2. 1990-09-20. PMID:2200595. |
since the hippocampus of the rat is involved in spatial navigation, learning, and memory, selective deficits in these abilities may arise from ischemic brain damage. |
1990-09-20 |
2023-08-11 |
rat |
| N Tamamaki, Y Nojy. Disposition of the slab-like modules formed by axon branches originating from single CA1 pyramidal neurons in the rat hippocampus. The Journal of comparative neurology. vol 291. issue 4. 1990-05-30. PMID:2329188. |
the hippocampus is thought to be an area where the neuronal circuits for short-term memory or the cognitive map may reside. |
1990-05-30 |
2023-08-11 |
rat |
| J S Taube, R U Muller, J B Ranc. Head-direction cells recorded from the postsubiculum in freely moving rats. II. Effects of environmental manipulations. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 10. issue 2. 1990-03-21. PMID:2303852. |
in the discussion, comparisons are drawn between the responses of head-direction cells and hippocampal place cells to similar environmental manipulations (muller and kubie, 1987), and ways in which these 2 spatial systems interact in navigation are discussed. |
1990-03-21 |
2023-08-11 |
rat |
| S I Wiener, C A Paul, H Eichenbau. Spatial and behavioral correlates of hippocampal neuronal activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 9. issue 8. 1989-09-22. PMID:2769364. |
the firing rate of hippocampal neurons in rats was related both to spatial location and to multiple behavioral variables as rats performed 2 kinds of tasks that rely on hippocampal function: a spatial navigation task similar in performance demands to the radial-arm maze task and a simultaneous cue odor-discrimination task. |
1989-09-22 |
2023-08-11 |
rat |
| R N Auer, M L Jensen, I Q Whisha. Neurobehavioral deficit due to ischemic brain damage limited to half of the CA1 sector of the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 9. issue 5. 1989-06-29. PMID:2723745. |
since the hippocampus is involved in spatial navigation, learning, and memory, selective deficits in these areas may arise from ischemic brain damage. |
1989-06-29 |
2023-08-11 |
rat |
| R N Auer, M L Jensen, I Q Whisha. Neurobehavioral deficit due to ischemic brain damage limited to half of the CA1 sector of the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 9. issue 5. 1989-06-29. PMID:2723745. |
the objective of this study was to test whether a minimal ischemic insult, producing selective neuronal necrosis restricted to only a portion of the ca1 pyramidal cells of the hippocampus, could produce a detectable spatial navigation deficit. |
1989-06-29 |
2023-08-11 |
rat |
| L H Goldstein, A G Canavan, C E Polke. Cognitive mapping after unilateral temporal lobectomy. Neuropsychologia. vol 27. issue 2. 1989-05-11. PMID:2927627. |
an investigation of the extension of o'keefe and nadel's [the hippocampus as a cognitive map. |
1989-05-11 |
2023-08-11 |
Not clear |
| W R Mundy, H A Tilso. Behavioral impairment in the rat after colchicine lesions of the hippocampus and nucleus basalis. Neurotoxicology. vol 9. issue 3. 1989-01-19. PMID:3200513. |
rats were given bilateral injections of colchicine into the nucleus basalis (nbm; 1.0 or 2.0 micrograms/site), hippocampus (hpc; 1.25 or 2.5 micrograms/site), or both areas (com; 1.0 nbm, 1.25 hpc) and examined for changes in locomotor activity, passive avoidance behavior, and spatial navigation in a water maze task. |
1989-01-19 |
2023-08-11 |
rat |
| J J Hagan, J D Salamone, J Simpson, S D Iversen, R G Morri. Place navigation in rats is impaired by lesions of medial septum and diagonal band but not nucleus basalis magnocellularis. Behavioural brain research. vol 27. issue 1. 1988-04-05. PMID:3342117. |
the data are discussed in the light of the hypothesis that the cholinergic innervation of the hippocampus plays a key role in spatial reference memory processes involved in place navigation. |
1988-04-05 |
2023-08-11 |
rat |
| T Leis, V Pallage, G Toniolo, B Wil. Working memory theory of hippocampal function needs qualification. Behavioral and neural biology. vol 42. issue 2. 1985-02-27. PMID:6525142. |
to compare the predictive value of "cognitive map" and "working memory" theories of hippocampal function, the performance of rats with dorsal hippocampal lesions was compared to that of control rats in a series of experiments. |
1985-02-27 |
2023-08-12 |
rat |
| I Q Whishaw, B Kol. Decortication abolishes place but not cue learning in rats. Behavioural brain research. vol 11. issue 2. 1984-05-16. PMID:6704233. |
the results demonstrate: (1) the integrity of the neocortex is essential for place learning; (2) the brainstem, including superior colliculus and basal ganglia, is sufficient for cue learning; and (3) in the absence of the neocortex the hippocampus plays no role in guiding either type of navigation. |
1984-05-16 |
2023-08-12 |
rat |