| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Judit Català-Solsona, Stefano Lutzu, Pablo J Lituma, Cristina Fábregas-Ordoñez, Dolores Siedlecki, Lydia Giménez-Llort, Alfredo J Miñano-Molina, Carlos A Saura, Pablo E Castillo, José Rodriguez-Álvare. Nr4a2 blocks oAβ-mediated synaptic plasticity dysfunction and ameliorates spatial memory deficits in the APP bioRxiv : the preprint server for biology. 2024-02-08. PMID:38328087. |
notably, nr4a2 overexpression in the hippocampus of ad mouse models ameliorates spatial learning and memory deficits. |
2024-02-08 |
2024-02-10 |
mouse |
| Adam P Caccavano, Sarah Kimmel, Anna Vlachos, Vivek Mahadevan, June Hoan Kim, Geoffrey Vargish, Ramesh Chittajallu, Edra London, Xiaoqing Yuan, Steven Hunt, Mark A G Eldridge, Alex C Cummins, Brendan E Hines, Anya Plotnikova, Arya Mohanty, Bruno B Averbeck, Kareem Zaghloul, Jordane Dimidschstein, Gord Fishell, Kenneth A Pelkey, Chris J McBai. Divergent opioid-mediated suppression of inhibition between hippocampus and neocortex across species and development. bioRxiv : the preprint server for biology. 2024-02-05. PMID:38313283. |
acute opioid-mediated modulation was partially occluded with morphine pretreatment, with implications for the effects of opioids on hippocampal network activity during circuit maturation as well as learning and memory. |
2024-02-05 |
2024-02-07 |
mouse |
| Qiong Wen, Fubing Zha, Linlin Shan, Shaohua Zhang, Peng Xiao, Chunxia Zhang, Haibo Yu, Yulong Wan. Electroacupuncture Attenuates Middle Cerebral Artery Occlusion-induced Learning and Memory Impairment by Regulating Microglial Polarization in Hippocampus. The International journal of neuroscience. 2024-02-05. PMID:38315119. |
electroacupuncture attenuates middle cerebral artery occlusion-induced learning and memory impairment by regulating microglial polarization in hippocampus. |
2024-02-05 |
2024-02-09 |
Not clear |
| Elina E Mäkinen, Sanna Lensu, Jan Wikgren, Satu Pekkala, Lauren G Koch, Steven L Britton, Miriam S Noki. Intrinsic running capacity associates with hippocampal electrophysiology and long-term potentiation in rats. Neuroscience letters. 2024-02-01. PMID:38301912. |
here we aimed to determine whether hippocampal electrophysiological activity related to learning and memory would be impaired in lcr compared to hcr rats. |
2024-02-01 |
2024-02-04 |
rat |
| Monica Goncalves-Garcia, Derek Alexander Hamilto. Unraveling the complex relationship between prenatal alcohol exposure, hippocampal LTP, and learning and memory. Frontiers in molecular neuroscience. vol 16. 2024-01-29. PMID:38283699. |
unraveling the complex relationship between prenatal alcohol exposure, hippocampal ltp, and learning and memory. |
2024-01-29 |
2024-01-31 |
Not clear |
| Kitty Reemst, Nicola Lopizzo, Maralinde R Abbink, Hendrik J Engelenburg, Annamaria Cattaneo, Aniko Koros. Molecular underpinnings of programming by early-life stress and the protective effects of early dietary ω6/ω3 ratio, basally and in response to LPS: Integrated mRNA-miRNAs approach. Brain, behavior, and immunity. 2024-01-19. PMID:38242369. |
under basal conditions both els and the diet affected molecular pathways related to hippocampal plasticity, with the protective (low ω6/ω3 ratio) diet leading to activation of molecular pathways associated with improved hippocampal plasticity and learning and memory in mice previously exposed to els (e.g., creb signaling and endocannabinoid neuronal synapse pathway). |
2024-01-19 |
2024-01-22 |
mouse |
| Kitty Reemst, Nicola Lopizzo, Maralinde R Abbink, Hendrik J Engelenburg, Annamaria Cattaneo, Aniko Koros. Molecular underpinnings of programming by early-life stress and the protective effects of early dietary ω6/ω3 ratio, basally and in response to LPS: Integrated mRNA-miRNAs approach. Brain, behavior, and immunity. 2024-01-19. PMID:38242369. |
this data provides molecular insights into how the protective (low ω6/ω3) diet during development could exert its long-lasting beneficial effects on hippocampal plasticity and learning and memory especially in a vulnerable population exposed to stress early in life, providing the basis for the development of intervention strategies. |
2024-01-19 |
2024-01-22 |
mouse |
| L Zokaei, E Akbari, V Babapour, M Zendehde. The Modulatory Role of Orexin 1 Receptor in Nucleus Accumbens (NAc) on Spatial Memory in Rats. Archives of Razi Institute. vol 78. issue 4. 2024-01-16. PMID:38226387. |
previous studies have shown the involvement of orexins and their role in learning and memory processes in the dorsal raphe nucleus and hippocampus. |
2024-01-16 |
2024-01-18 |
rat |
| Guven Akcay, Anzel Bahadir, Yakup Tatar, Mehmet Nuri Atalar, Cahit Babur, Aysegul Taylan Ozka. Investigation of the effects of Toxoplasma gondii on behavioral and molecular mechanism in bradyzoite stage. Brain research. 2024-01-16. PMID:38228258. |
in our study, the effects of t. gondii on locomotor activity, anxiety, learning and memory, and norepinephrine (ne), levodopa (l-dopa), dopamine (da) and 3,4-d-dihydroxyphenylacetic acid (dopac) catecholamines in amygdala, striatum, prefrontal cortex and hippocampus regions of the brain were investigated in bradyzoite stage. |
2024-01-16 |
2024-01-19 |
mouse |
| Xi Zhang, Hong Zheng, Zhitao Ni, Yuyin Shen, Die Wang, Wenqing Li, Liangcai Zhao, Chen Li, Hongchang Ga. Fibroblast growth factor 21 alleviates diabetes-induced cognitive decline. Cerebral cortex (New York, N.Y. : 1991). 2024-01-14. PMID:38220573. |
results revealed that i.c.v fgf21 infusion effectively improved learning and memory performance of dicd mice; neuron loss and apoptosis in hippocampus and cortex were significantly blocked, suggesting a potential neuroprotective role of fgf21 in dicd. |
2024-01-14 |
2024-01-17 |
mouse |
| Aditi Methi, Md Rezaul Islam, Lalit Kaurani, M Sadman Sakib, Dennis M Krüger, Tonatiuh Pena, Susanne Burkhardt, David Liebetanz, André Fische. A Single-Cell Transcriptomic Analysis of the Mouse Hippocampus After Voluntary Exercise. Molecular neurobiology. 2024-01-13. PMID:38217668. |
exercise has been recognized as a beneficial factor for cognitive health, particularly in relation to the hippocampus, a vital brain region responsible for learning and memory. |
2024-01-13 |
2024-01-16 |
mouse |
| Charlene P Poore, Nurul A M N Hazalin, Shunhui Wei, See Wee Low, Bo Chen, Bernd Nilius, Zurina Hassan, Ping Lia. TRPM4 blocking antibody reduces neuronal excitotoxicity by specifically inhibiting glutamate-induced calcium influx under chronic hypoxia. Neurobiology of disease. 2024-01-10. PMID:38199274. |
using a rat model of chronic hypoxia with both common carotid arteries occluded, we found that m4p treatment could reduce apoptosis in the neurons within the hippocampus, attenuate long-term potentiation impairment and improve the functions of learning and memory in this rat model. |
2024-01-10 |
2024-01-13 |
rat |
| Clement Poiret, Antoine Bouyeure, Sandesh Patil, Cécile Boniteau, Edouard Duchesnay, Antoine Grigis, Frederic Lemaitre, Marion Noulhian. Attention-gated 3D CapsNet for robust hippocampal segmentation. Journal of medical imaging (Bellingham, Wash.). vol 11. issue 1. 2024-01-04. PMID:38173654. |
the hippocampus is organized in subfields (hsf) involved in learning and memory processes and widely implicated in pathologies at different ages of life, from neonatal hypoxia to temporal lobe epilepsy or alzheimer's disease. |
2024-01-04 |
2024-01-06 |
Not clear |
| Rong-Xin Zou, Xiaozhen Gu, Chenqing Huang, Hui-Li Wang, Xiang-Tao Che. Chronic Pb exposure impairs learning and memory abilities by inhibiting excitatory projection neuro-circuit of the hippocampus in mice. Toxicology. 2023-12-31. PMID:38160928. |
chronic pb exposure impairs learning and memory abilities by inhibiting excitatory projection neuro-circuit of the hippocampus in mice. |
2023-12-31 |
2024-01-05 |
mouse |
| Kunqiang Yu, Ri Xu, Lixu Wu, Weiwei Li, Ruhui Lin, Mengyuan Dai, Xu M. Effects of microRNA-320 on learning and memory in mice with vascular cognitive impairment caused via cerebral ischemia. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 13. 2023-12-30. PMID:38158679. |
after establishment of a cerebral small vessel disease (csvd) cognitive impairment model, application of corresponding treatment methods was in the model mice to inject mir-320 antagomir/agomir and their negative controls to the lateral ventricles: test of the learning and memory abilities of mice was conducted; detection of oxidative stress, inflammation, mir-320, vascular endothelial growth factor (vegf) and endostatin (es) was implemented; taking mouse hippocampal neuron cells was to detect the cell advancement. |
2023-12-30 |
2024-01-05 |
mouse |
| Mahdi Khorsand Ghaffari, Ali Rafati, Narges Karbalaei, Masoud Haghani, Marzieh Nemati, Niloofar Sefati, Mohammad Reza Namava. The effect of intra-nasal co-treatment with insulin and growth factor-rich serum on behavioral defects, hippocampal oxidative-nitrosative stress, and histological changes induced by icv-STZ in a rat model. Naunyn-Schmiedeberg's archives of pharmacology. 2023-12-29. PMID:38157024. |
we found that icv-stz injection (3 mg/kg bilaterally) impairs spatial learning and memory in morris water maze, leads to anxiogenic-like behavior in the open field arena, and induces oxidative-nitrosative stress, neuroinflammation, and neuronal/oligodendroglia death in the hippocampus. |
2023-12-29 |
2024-01-05 |
rat |
| Mengmeng Wang, Yanzhou Xia, Shu Ai, Xiaozhen Gu, Hui-Li Wan. Kaempferol improves Pb-induced cognitive impairments via inhibiting autophagy. The Journal of nutritional biochemistry. 2023-12-27. PMID:38151193. |
the results found kam treatment improved the learning and memory ability and alleviated hippocampal neuronal pathological damages. |
2023-12-27 |
2023-12-30 |
rat |
| Yu-Han Xie, Lin Jiang, Yi Zhang, Yu-Hui Deng, Hao Yang, Qi He, Yu-Ning Zhou, Chun-Ni Zhou, Yan-Min Luo, Xin Liang, Jin Wang, Du-Juan Huang, Lin Zhu, Yong Tang, Feng-Lei Cha. Antagonizing LINGO-1 reduces activated microglia and alleviates dendritic spine loss in the hippocampus of APP/PS1 transgenic mice. Neuroscience letters. 2023-12-24. PMID:38142924. |
the anti-lingo-1 antibody significantly reversed these changes in ad, indicating that the anti-lingo-1 antibody can improve hippocampus-dependent learning and memory abilities and effectively rescue dendritic spines in the hippocampus of ad mice and that microglia might participate in this progression in ad. |
2023-12-24 |
2023-12-27 |
mouse |
| Danyang Wang, Bin Yan, An Wang, Qing Sun, Junyi Pang, Yangming Cui, Guoqing Tia. Tu-Xian Decoction ameliorates diabetic cognitive impairment by inhibiting DAPK-1. Chinese journal of natural medicines. vol 21. issue 12. 2023-12-24. PMID:38143108. |
the results revealed that txd significantly improved spatial learning and memory abilities, and preserved hippocampal structure in diabetic rats. |
2023-12-24 |
2023-12-27 |
rat |
| He Huang, Ashley J van Waardenberg, Mark E Graham, Victor Anggono, Jocelyn Widagd. Global quantitative proteomic analysis of aged mouse hippocampus. Proteomics. 2023-12-20. PMID:38115172. |
focusing on the hippocampus, a critical brain region involved in learning and memory, we employed tandem mass tag methodology to investigate global proteomic changes that occur in advanced-aged (20-month) versus young (3-month) c57bl/6 male mice. |
2023-12-20 |
2023-12-23 |
mouse |