| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jingyuan Ma, Feng Xiong, Zhouru Li, Guokai Dong, Xiaoming Sun, Wenjiang Yin, Hongxing Ca. The effect of chronic alcohol exposure on spatial memory and BDNF-TrkB- PLCγ1 signaling in the hippocampus of male and female mice. Heliyon. vol 9. issue 6. 2023-06-12. PMID:37303582. |
given previously known effects of brain-derived neurotrophic factor (bdnf) in regulating synaptic plasticity and learning and memory, we investigated the effect of chronic alcohol consumption on spatial memory impairment in both sexes and changes in bdnf signaling in the hippocampus. |
2023-06-12 |
2023-08-14 |
mouse |
| Leigang Song, Huan Chen, Dan Qiao, Bohan Zhang, Fangzhen Guo, Yizhou Zhang, Chang Wang, Sha Li, Huixian Cu. ZIP9 mediates the effects of DHT on learning, memory and hippocampal synaptic plasticity of male Tfm and APP/PS1 mice. Frontiers in endocrinology. vol 14. 2023-06-12. PMID:37305050. |
compared with wild-type (wt) male mice, we found that ar-deficient male testicular feminization mutation (tfm) mice with low androgen levels had learning and memory impairment, decreased expression of hippocampal synaptic proteins psd95, drebrin, syp, and dendritic spine density. |
2023-06-12 |
2023-08-14 |
mouse |
| Leigang Song, Huan Chen, Dan Qiao, Bohan Zhang, Fangzhen Guo, Yizhou Zhang, Chang Wang, Sha Li, Huixian Cu. ZIP9 mediates the effects of DHT on learning, memory and hippocampal synaptic plasticity of male Tfm and APP/PS1 mice. Frontiers in endocrinology. vol 14. 2023-06-12. PMID:37305050. |
finally, we found that zip9 mediated the effects of dht on the expression of synaptic proteins psd95, drebrin, syp, and dendritic spine density in the hippocampus of app/ps1 mice through the erk1/2-eif4e pathway and affected learning and memory. |
2023-06-12 |
2023-08-14 |
mouse |
| Sung-Hoon Kim, Jung-Hyun Choi, Laura Marsal-García, Mehdi Amiri, Akiko Yanagiya, Nahum Sonenber. The mRNA translation initiation factor eIF4G1 controls mitochondrial oxidative phosphorylation, axonal morphogenesis, and memory. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 25. 2023-06-12. PMID:37307456. |
the axonal arborization of eif4g1-1d primary hippocampal neurons was significantly disrupted, and the mice displayed impairment in hippocampus-dependent learning and memory. |
2023-06-12 |
2023-08-14 |
mouse |
| Yong-Xin Chen, Hong Yang, Da-Song Wang, Yu-Ting Yao, Ting-Ting Chen, Ling Tao, Yan Chen, Xiang-Chun She. Gastrodin relieves cognitive impairment by regulating autophagy via PI3K/AKT signaling pathway in vascular dementia. Biochemical and biophysical research communications. vol 671. 2023-06-12. PMID:37307708. |
the study showed that gas relieved learning and memory deficits, ameliorated hippocampus histological lesions in vad rats. |
2023-06-12 |
2023-08-14 |
rat |
| Xiao-Bo Bi, Xia Zhang, Ji-Peng Wen, Wei Ding, Jin L. [Effects of repeated sevoflurane exposure on hippocampal cell apoptosis and long-term learning and memory ability in neonatal rats]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 38. issue 6. 2023-06-12. PMID:37308440. |
[effects of repeated sevoflurane exposure on hippocampal cell apoptosis and long-term learning and memory ability in neonatal rats]. |
2023-06-12 |
2023-08-14 |
rat |
| Fatemeh Abolhasani, Yaghoub Pourshojaei, Fatemeh Mohammadi, Khadijeh Esmaeilpour, Ali Asadipour, Mehran Ilaghi, Mohammad Shaban. Exploring the potential of a novel phenoxyethyl piperidine derivative with cholinesterase inhibitory properties as a treatment for dementia: insights from STZ animal model of dementia. Neuroscience letters. 2023-06-11. PMID:37302565. |
in the current study, we assessed the effects of a synthetic phenoxyethyl piperidine derivative, compound 7c, as a novel dual inhibitor of acetylcholinesterase (ache) and butyrylcholinesterase (buche), on learning and memory, as well as serum and hippocampal ache levels in an animal model of ad. |
2023-06-11 |
2023-08-14 |
human |
| Eduarda G Nachtigall, Júlia D R de Freitas, Jociane de C Myskiw, Cristiane R G Furin. Role of hippocampal Wnt signaling pathways on contextual fear memory reconsolidation. Neuroscience. 2023-06-07. PMID:37286160. |
it is known the wnt signaling pathways can modulate hippocampal synaptic plasticity as well as learning and memory. |
2023-06-07 |
2023-08-14 |
Not clear |
| Samira Choopani, Bahereh Kiani, Shayan Aliakbari, Jalal Babaie, Majid Golkar, Hamid Gholami Pourbadie, Mohammad Sayya. Latent toxoplasmosis impairs learning and memory yet strengthens short-term and long-term hippocampal synaptic plasticity at perforant pathway-dentate gyrus, and Schaffer collatterals-CA1 synapses. Scientific reports. vol 13. issue 1. 2023-06-02. PMID:37268701. |
latent toxoplasmosis impairs learning and memory yet strengthens short-term and long-term hippocampal synaptic plasticity at perforant pathway-dentate gyrus, and schaffer collatterals-ca1 synapses. |
2023-06-02 |
2023-08-14 |
rat |
| Suhel Parvez, Binu Ramachandran, Medha Kaushik, Heena Tabassum, Julietta U Fre. Long-term depression induction and maintenance across regions of the apical branch of CA1 dendrites. Hippocampus. 2023-05-31. PMID:37254828. |
well known as the center for learning and memory, hippocampus is the crucial brain region to study synaptic plasticity in the context of cellular fundamental mechanisms such as long-term depression (ltd) and long-term potentiation (ltp). |
2023-05-31 |
2023-08-14 |
rat |
| Shogo Soma, Shinya Ohara, Satoshi Nonomura, Naofumi Suematsu, Junichi Yoshida, Eva Pastalkova, Yutaka Sakai, Ken-Ichiro Tsutsui, Yoshikazu Isomur. Rat hippocampal CA1 region represents learning-related action and reward events with shorter latency than the lateral entorhinal cortex. Communications biology. vol 6. issue 1. 2023-05-31. PMID:37258700. |
the hippocampus and entorhinal cortex are deeply involved in learning and memory. |
2023-05-31 |
2023-08-14 |
rat |
| Zijuan Zhang, Ziyang Yu, Ye Yuan, Jing Yang, Shijie Wang, He Ma, Li Hao, Jinlian Ma, Zhonghua Li, Zhenqiang Zhang, Christian Hölsche. Cholecystokinin Signaling can Rescue Cognition and Synaptic Plasticity in the APP/PS1 Mouse Model of Alzheimer's Disease. Molecular neurobiology. 2023-05-29. PMID:37247071. |
our study found that the cck analogue could effectively improve spatial learning and memory, enhance synaptic plasticity in the hippocampus, normalize synapse numbers and morphology and the levels of key synaptic proteins, up-regulate the pi3k/akt signaling pathway and normalize pka, creb, bdnf and trkb receptor levels in app/ps1 mice. |
2023-05-29 |
2023-08-14 |
mouse |
| Yuta Madokoro, Daisuke Kato, Yo Tsuda, Itsumi Arakawa, Kengo Suzuki, Toyohiro Sato, Masayuki Mizuno, Yuto Uchida, Kosei Ojika, Noriyuki Matsukaw. Direct Enhancement Effect of Hippocampal Cholinergic Neurostimulating Peptide on Cholinergic Activity in the Hippocampus. International journal of molecular sciences. vol 24. issue 10. 2023-05-27. PMID:37240261. |
the cholinergic efferent network from the medial septal nucleus to the hippocampus is crucial for learning and memory. |
2023-05-27 |
2023-08-14 |
mouse |
| Carolina Gaudenzi, Karen Rosemary Mifsud, Johannes Reu. Insights into isoform-specific mineralocorticoid receptor action in the hippocampus. The Journal of endocrinology. 2023-05-26. PMID:37235709. |
in the hippocampus, the mr has been implicated in several processes, such as neuronal maintenance, adult neurogenesis, inhibitory control of the hypothalamic-pituitary-adrenal (hpa) axis, and learning and memory. |
2023-05-26 |
2023-08-14 |
mouse |
| Bakhtiarzadeh Fatemeh, Shahpasand Koorosh, Shojaei Amir, Fathollahi Yaghoub, Mirnajafi-Zadeh Java. Intra-hippocampal cis-P tau microinjection induces long-term changes in behavior and synaptic plasticity in mice. Behavioral and brain functions : BBF. vol 19. issue 1. 2023-05-25. PMID:37231523. |
the present study investigated the long-term effects of tauopathy on learning and memory, synaptic plasticity, and hippocampal cell numbers. |
2023-05-25 |
2023-08-14 |
mouse |
| Yulong Wu, Zhouyan Dong, Xinze Jiang, Lei Qu, Wei Zhou, Xu Sun, Jiangshan Hou, Hongmei Xu, Mei Chen. Gut Microbiota Taxon-Dependent Transformation of Microglial M1/M2 Phenotypes Underlying Mechanisms of Spatial Learning and Memory Impairment after Chronic Methamphetamine Exposure. Microbiology spectrum. 2023-05-22. PMID:37212669. |
here, we investigated the impact of the gut microbiota on the phenotype status of microglia (microglial phenotypes m1 and microglial m2) and their secreting factors, the subsequent hippocampal neural processes, and the resulting influence on spatial learning and memory of chronically meth-exposed mice. |
2023-05-22 |
2023-08-14 |
mouse |
| Ning Kang, Xiaoguang Han, Zhengqian Li, Taotao Liu, Xinning Mi, Yue Li, Xiangyang Guo, Dengyang Han, Ning Yan. Rapamycin Affects the Hippocampal SNARE Complex to Alleviate Cognitive Dysfunction Induced by Surgery in Aged Rats. Brain sciences. vol 13. issue 4. 2023-05-16. PMID:37190563. |
here, we evaluated the effects of propofol anesthesia plus surgery on learning and memory and investigated levels of snare proteins and chaperones in hippocampal synaptosomes. |
2023-05-16 |
2023-08-14 |
rat |
| Daniela Madeira, Cátia R Lopes, Ana P Simões, Paula M Canas, Rodrigo A Cunha, Paula Agostinh. Astrocytic A Glia. 2023-05-15. PMID:37183905. |
astrocytic a astrocytes are wired to bidirectionally communicate with neurons namely with synapses, thus shaping synaptic plasticity, which in the hippocampus is considered to underlie learning and memory. |
2023-05-15 |
2023-08-14 |
Not clear |
| Robert J McDonald, Nancy S Hong, Jan S Trow, Chelsea Kaupp, R J Balog, London Gokarn, Erin A Falkenberg, Keiko J McCreary, Nasrin Soltanpour, Carter Witbeck, Aimee McKenna, Gerlinde A S Met. Effects of maternal social isolation on adult rodent offspring cognition. Scientific reports. vol 13. issue 1. 2023-05-14. PMID:37173349. |
accordingly, for this study we were interested in the effects of maternal stress induced via social isolation on adult offspring cognitive functions including spatial, stimulus-response, and emotional learning and memory that are mediated by different networks centered on the hippocampus, dorsal striatum, and amygdala, respectively. |
2023-05-14 |
2023-08-14 |
rat |
| Joseph A Kostansek, Gavin J Latona, Segewkal H Heruye, Stephanie Matthews, Charles S Bockman, Kristina A Simeone, Timothy A Simeon. Orexin receptors regulate hippocampal sharp wave-ripple complexes in ex vivo slices. European journal of pharmacology. 2023-05-05. PMID:37146705. |
our study indicates an orexin contribution to hippocampal sharp wave-ripple complexes and suggests a mechanism by which sub-homeostatic concentrations of orexin may inhibit learning and memory function. |
2023-05-05 |
2023-08-14 |
Not clear |