| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuanyu Song, Yinghua Chen, Wei Sun, Changqing Li, Junfeng Li, Haoyu Wang, Ruiqi Qin, Xiaoqing Su, Tong Wu, Hongxu Zhao, Yusheng Ha. [Exploration of electroacupuncture at "Fengchi" (GB 20) and "Sishencong" (EX-HN 1) for attenuating learning and memory impairment in vascular dementia rats based on NMDAR/CREB/BDNF signaling pathway]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. vol 44. issue 12. 2024-12-10. PMID:39658379. |
to explore the mechanism of electroacupuncture (ea) at "fengchi" (gb 20) and "sishencong" (ex-hn 1) on learning and memory impairment in vascular dementia (vd) rats by observing the influences on the n-methyl-d-aspartate receptor (nmdar)/cyclic adenosine monophosphate response element-binding protein (creb)/brain-derived neurotrophic factor (bdnf) signaling pathway and the excitotoxicity induced by hippocampal calcium overload. |
2024-12-10 |
2024-12-13 |
rat |
| Jia-Qi Ma, Lu Wang, Yue Zhang, Yong-Qian Bian, Xiao-Peng Qu, Li-Jia Song, Chao Wang, Li Gao, Qi-Xing Fang, De-Chang Zhao, Liang-Liang Shen, Bei Li. Single-nucleus RNA sequencing-based construction of a hippocampal neuron atlas in mice with epileptic cognitive impairment. iScience. vol 27. issue 10. 2024-12-05. PMID:39635132. |
the hippocampus plays a critical role in learning and memory, and mice with epileptic cognitive impairment exhibit hippocampal atrophy. |
2024-12-05 |
2024-12-07 |
mouse |
| Aubrey M Demchuk, Ingrid M Esteves, Bruce L McNaughto. Non-maternal nest building behaviours in mice predict bilateral dorsal hippocampal lesion extent. Behavioural brain research. 2024-12-04. PMID:39631505. |
lesions and pharmacological inactivation of the hippocampus have long been important tools for assessing the critical role of the hippocampus in learning and memory. |
2024-12-04 |
2024-12-07 |
mouse |
| Maryam Dastan, Ziba Rajaei, Mohammadreza Sharifi, Hossein Saleh. Crocin Improves Cognitive Impairment in LPS-treated Rats through Anti-Apoptotic, Anti-Inflammatory, and Antioxidant Activities. Molecular neurobiology. 2024-12-04. PMID:39630406. |
the results indicated that lps administration caused spatial learning and memory dysfunction (p = 0.001, p < 0.01) accompanied by upregulation of nfkb, tnfα, and casp3 mrna expression (p < 0.0001), increased tnf-α (p < 0.01) and lipid peroxidation level (p < 0.01), decreased total thiol concentration (p < 0.05), tissue damage and neuronal loss in the hippocampus (p < 0.0001). |
2024-12-04 |
2024-12-06 |
rat |
| Maryam Dastan, Ziba Rajaei, Mohammadreza Sharifi, Hossein Saleh. Crocin Improves Cognitive Impairment in LPS-treated Rats through Anti-Apoptotic, Anti-Inflammatory, and Antioxidant Activities. Molecular neurobiology. 2024-12-04. PMID:39630406. |
furthermore, crocin treatment at a dosage of 100 mg/kg attenuated learning and memory impairments (p = 0.001, p < 0.01), downregulated nfkb, tnfα, and casp3 mrna expression (p < 0.0001), decreased tnf-α level (p < 0.01) and lipid peroxidation (p < 0.05) and increased total thiol level (p < 0.05) in the hippocampus. |
2024-12-04 |
2024-12-06 |
rat |
| J Quinn Lee, Matt Nielsen, Rebecca McHugh, Erik Morgan, Nancy S Hong, Robert J Sutherland, Robert J McDonal. Sparsity of Population Activity in the Hippocampus Is Task-Invariant Across the Trisynaptic Circuit and Dorsoventral Axis. Hippocampus. vol 35. issue 1. 2024-12-02. PMID:39620324. |
importantly, representational sparsity has significant implications for neural computation and theoretical models of learning and memory within and beyond the hippocampus. |
2024-12-02 |
2024-12-06 |
rat |
| Robert J McDonald, Joelle Kopp, Erin L Zelinski, Robert J Sutherland, Hugo Lehmann, Fraser Sparks, Nancy S Hon. Anterograde versus Retrograde Effects of Damage to Identified Learning and Memory Systems during Acquisition, Retention, and Re-Acquisition of an Instrumental Visual Discrimination Task: Dorsal Striatum, Perirhinal Cortex, and Hippocampus. Journal of integrative neuroscience. vol 23. issue 11. 2024-11-29. PMID:39613472. |
anterograde versus retrograde effects of damage to identified learning and memory systems during acquisition, retention, and re-acquisition of an instrumental visual discrimination task: dorsal striatum, perirhinal cortex, and hippocampus. |
2024-11-29 |
2024-12-02 |
Not clear |
| Ziyao Han, Xiaoyue Yang, Jianxiong Gui, Hanyu Luo, Dishu Huang, Hengsheng Chen, Li Cheng, Ping Yuan, Li Jian. Defective Hippocampal Primary Ciliary Function and Aberrant LKB1/AMPK Signaling Pathway Are Associated With the Inhibition of Autophagic Activity in Offspring Born to Mothers of Advanced Maternal Age. Developmental neurobiology. vol 85. issue 1. 2024-11-28. PMID:39604128. |
as hippocampal autophagy and primary cilia play a crucial role in learning and memory abilities, this study aimed to investigate the effects of ama on hippocampal autophagy and primary cilia, and to explore their relationship with the changes of lkb1/ampk signaling pathway in offspring rats. |
2024-11-28 |
2024-11-30 |
rat |
| Christopher D Adam, Emily D Schellinger, Alicia White, Srdjan M Joksimovic, Hajime Takano, Douglas A Coulte. Chemogenetic Breakdown of the Dentate Gate Causes Seizures and Spatial Memory Deficits. bioRxiv : the preprint server for biology. 2024-11-28. PMID:39605633. |
effective gating is thought to prevent seizure initiation and propagation in the hippocampus and support learning and memory processes. |
2024-11-28 |
2024-11-30 |
mouse |
| Mousa Shaabani Ghahremanlo, Vida Hojati, Gholamhassan Vaezi, Shahram Sharaf. Transgenerational of Oxidative Damage Induced by Prenatal Ethanol Exposure on Spatial Learning/Memory and BDNF in the of Male Rats. IBRO neuroscience reports. vol 17. 2024-11-25. PMID:39583589. |
this study investigates how prenatal ethanol exposure triggers oxidative stress (os) and affects neurotrophic factors (ntfs), particularly brain-derived growth factor (bdnf) gene expression in the hippocampus, influencing learning and memory decline across two generations of male offspring from ethanol-exposed female rats. |
2024-11-25 |
2024-11-27 |
rat |
| Erika R Carlson, Jennifer K Melbourne, Kimberly Nixo. Pharmacological depletion of microglia protects against alcohol-induced corticolimbic neurodegeneration during intoxication in male rats. bioRxiv : the preprint server for biology. 2024-11-22. PMID:39574620. |
excessive alcohol use damages the brain, especially corticolimbic regions such as the hippocampus and rhinal cortices, leading to learning and memory problems. |
2024-11-22 |
2024-11-24 |
mouse |
| Maryam Dastan, Ziba Rajaei, Mohammadreza Sharifi, Hossein Saleh. Gallic acid ameliorates LPS-induced memory decline by modulating NF-κB, TNF-α, and Caspase 3 gene expression and attenuating oxidative stress and neuronal loss in the rat hippocampus. Metabolic brain disease. vol 40. issue 1. 2024-11-18. PMID:39556267. |
lps treatment resulted in spatial learning and memory impairment, upregulation of nf-κb, tnf-α, and caspase 3 mrna expression, increased lipid peroxidation, decreased total thiol level, and neuronal loss in the hippocampus. |
2024-11-18 |
2024-11-22 |
rat |
| Kui Wang, Haidong Wei, Liufei Yang, Shuyue Zhang, Yiqin Cheng, Chen Li, Pengyu Jia, Yuanyuan Zhang, Yan Zhang, Pei Fan, Ning Wang, Haixia Lu, Xinlin Chen, Yong Liu, Pengbo Zhan. Pretreatment with tetramethylpyrazine alleviated the impairment of learning and memory induced by sevoflurane exposure in neonatal rats. Neuroscience. 2024-11-14. PMID:39542344. |
these findings indicated that pretreatment with tetramethylpyrazine alleviated the impairment of learning and memory induced by sevoflurane through improvement of hippocampal synaptic plasticity in neonatal rats. |
2024-11-14 |
2024-11-17 |
rat |
| Linping Wang, Weiyao Wang, Yingshun Li, Hua Jin, Bin Xiao, Qinghua Ji. Dopamine and D1 receptor in hippocampal dentate gyrus involved in chronic stress-induced alteration of spatial learning and memory in rats. Neurobiology of stress. vol 33. 2024-11-14. PMID:39524935. |
dopamine and d1 receptor in hippocampal dentate gyrus involved in chronic stress-induced alteration of spatial learning and memory in rats. |
2024-11-14 |
2024-11-17 |
rat |
| Linping Wang, Weiyao Wang, Yingshun Li, Hua Jin, Bin Xiao, Qinghua Ji. Dopamine and D1 receptor in hippocampal dentate gyrus involved in chronic stress-induced alteration of spatial learning and memory in rats. Neurobiology of stress. vol 33. 2024-11-14. PMID:39524935. |
dopamine (da) plays a critical role in learning and memory in the hippocampus through the activation of d1-like receptors (d1r). |
2024-11-14 |
2024-11-17 |
rat |
| Linping Wang, Weiyao Wang, Yingshun Li, Hua Jin, Bin Xiao, Qinghua Ji. Dopamine and D1 receptor in hippocampal dentate gyrus involved in chronic stress-induced alteration of spatial learning and memory in rats. Neurobiology of stress. vol 33. 2024-11-14. PMID:39524935. |
however, the specific roles of da and d1r in the hippocampal dentate gyrus (dg), particularly in cs-induced changes in spatial learning and memory, are not well understood. |
2024-11-14 |
2024-11-17 |
rat |
| Aspen M Harter, Mariya Nemesh, Michelle T Ji, Luca Lee, Anna Yamazaki, Chris Kim, Eva E Rede. Female Wistar Kyoto More Immobile rats with genetic stress hyper-reactivity show enhanced contextual fear memory without deficit in extinction of fear. The European journal of neuroscience. 2024-11-10. PMID:39523452. |
hippocampal expressions of genes relevant to both learning and memory and the stress response were decreased in stressed wmis compared to wli females, further suggesting a marked dysregulation in stress-related functions like in ptsd. |
2024-11-10 |
2024-11-17 |
rat |
| Marcela Salazar-García, Laura Villavicencio-Guzmán, Cristina Revilla-Monsalve, Carlos César Patiño-Morales, Ricardo Jaime-Cruz, Tania Cristina Ramírez-Fuentes, Juan Carlos Coron. Harmful Effects on the Hippocampal Morpho-Histology and on Learning and Memory in the Offspring of Rats with Streptozotocin-Induced Diabetes. International journal of molecular sciences. vol 25. issue 21. 2024-11-09. PMID:39518888. |
harmful effects on the hippocampal morpho-histology and on learning and memory in the offspring of rats with streptozotocin-induced diabetes. |
2024-11-09 |
2024-11-17 |
rat |
| Marcela Salazar-García, Laura Villavicencio-Guzmán, Cristina Revilla-Monsalve, Carlos César Patiño-Morales, Ricardo Jaime-Cruz, Tania Cristina Ramírez-Fuentes, Juan Carlos Coron. Harmful Effects on the Hippocampal Morpho-Histology and on Learning and Memory in the Offspring of Rats with Streptozotocin-Induced Diabetes. International journal of molecular sciences. vol 25. issue 21. 2024-11-09. PMID:39518888. |
we evaluate the effect of the hyperglycemic intrauterine environment on hippocampal histomorphometry in offspring, correlating it with spatial learning and memory, as well as the morphology of dendrites and spines in 30-day-old pups (p30). |
2024-11-09 |
2024-11-17 |
rat |
| Xinlong Zhang, Yue Feng, Yi Zhong, Rui Ding, Yaoyi Guo, Fan Jiang, Yan Xing, Hongwei Shi, Hongguang Bao, Yanna S. Dexmedetomidine Attenuates Neuroinflammation-Mediated Hippocampal Neurogenesis Impairment in Sepsis-Associated Encephalopathy Mice through Central α2A-Adrenoceptor. ACS chemical neuroscience. 2024-11-08. PMID:39513993. |
clp-induced astrocyte-related neuroinflammation and hippocampal neurogenesis deficits, accompanied by learning and memory decline, which were reversed by dexmedetomidine. |
2024-11-08 |
2024-11-16 |
mouse |