All Relations between learning and memory and synaptic plasticity

Publication Sentence Publish Date Extraction Date Species
Tue G Banke, Stephen F Traynelis, Andres Barri. Early Expression of GluN2A-Containing NMDA Receptors in A Model of Fragile X Syndrome. Journal of neurophysiology. 2024-02-21. PMID:38380828. nmda-type glutamate receptors (nmdars) play a crucial role in synaptogenesis, circuit development, and synaptic plasticity, serving as fundamental components in cellular models of learning and memory. 2024-02-21 2024-02-23 mouse
Svitlana V Bach, Allison J Bauman, Darya Hosein, Jennifer J Tuscher, Lara Ianov, Kelsey M Greathouse, Benjamin W Henderson, Jeremy H Herskowitz, Keri Martinowich, Jeremy J Da. Distinct roles of Bdnf I and Bdnf IV transcript variant expression in hippocampal neurons. Hippocampus. 2024-02-16. PMID:38362938. brain-derived neurotrophic factor (bdnf) plays a critical role in brain development, dendritic growth, synaptic plasticity, as well as learning and memory. 2024-02-16 2024-02-18 rat
Yinghan Zhuang, Chuhan Li, Fang Zhao, Yan Yan, Hongjie Pan, Jianmin Zhan, Thomas Behnisc. E3 Ubiquitin Ligase International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38338822. given the role of the ubiquitin-proteasome system (ups) in various nervous system processes, including learning and memory, we were particularly interested in exploring the involvement of ring-type ubiquitin e3 ligases, such as uhrf2 (nirf), in social behavior and synaptic plasticity. 2024-02-10 2024-02-12 mouse
Judit Català-Solsona, Stefano Lutzu, Pablo J Lituma, Cristina Fábregas-Ordoñez, Dolores Siedlecki, Lydia Giménez-Llort, Alfredo J Miñano-Molina, Carlos A Saura, Pablo E Castillo, José Rodriguez-Álvare. Nr4a2 blocks oAβ-mediated synaptic plasticity dysfunction and ameliorates spatial memory deficits in the APP bioRxiv : the preprint server for biology. 2024-02-08. PMID:38328087. nr4a2 blocks oaβ-mediated synaptic plasticity dysfunction and ameliorates spatial memory deficits in the app alzheimer's disease ad is associated with disruptions in neuronal communication, especially in brain regions crucial for learning and memory, such as the hippocampus. 2024-02-08 2024-02-10 mouse
Wenbin Zhang, Jiaqi Zhang, Zhongqi Zhang, Shuhan Cha, Jiong Li, Li Chen, Jiaming Wu, Jijun Teng, Guoqing Guo, Jifeng Zhan. Effects of DeSUMOylated Spastin on AMPA Receptor Surface Delivery and Synaptic Function Are Enhanced by Phosphorylating at Ser210. Molecular neurobiology. 2024-01-24. PMID:38267753. surface trafficking of ampa receptors (ampars) is one of the important mechanisms mediating synaptic plasticity which is essential for cognitive functions such as learning and memory. 2024-01-24 2024-01-27 Not clear
Valérie Clavet-Fournier, ChungKu Lee, Waja Wegner, Nils Brose, JeongSeop Rhee, Katrin I Willi. Pre- and postsynaptic nanostructures increase in size and complexity after induction of long-term potentiation. iScience. vol 27. issue 1. 2024-01-12. PMID:38213627. synaptic plasticity involves changes in synaptic morphology and the number of neurotransmitter receptors, and is thought to underlie learning and memory. 2024-01-12 2024-01-14 Not clear
Hou-Yuan Huang, Shelbi Salinas, Jessica Cornell, Iquo-Bella Udoh, Yang Shen, Miou Zho. CCR5 regulates Aβ Neurobiology of learning and memory. 2024-01-12. PMID:38215963. recently, ccr5 has also been reported to play a role in synaptic plasticity, learning and memory, and cognitive deficits associated with normal aging, traumatic brain injury (tbi), and hiv-associated neurocognitive disorder (hand). 2024-01-12 2024-01-15 mouse
Chad M Heer, Mark E J Sheffiel. Distinct catecholaminergic pathways projecting to hippocampal CA1 transmit contrasting signals during behavior and learning. bioRxiv : the preprint server for biology. 2023-12-11. PMID:38076843. neuromodulatory inputs to the hippocampus play pivotal roles in modulating synaptic plasticity, shaping neuronal activity, and influencing learning and memory. 2023-12-11 2023-12-17 mouse
Lei Dong, Ling Zhao, Lei Tian, Wenjun Zhao, Chan Xiong, Yu Zhen. AsHC 360 Exposure Influence on Epileptiform Discharges in Hippocampus of Infantile Male Rats In Vitro. International journal of molecular sciences. vol 24. issue 23. 2023-12-09. PMID:38069126. they can penetrate the blood-brain barrier, specifically affecting synaptic plasticity and the learning and memory ability of hippocampal neurons. 2023-12-09 2023-12-17 rat
Jongkyun Kang, Chen Zhang, Yuhao Wang, Jian Feng, Bonnie Berger, Norbert Perrimon, Jie She. Lipophorin Receptors Genetically Modulate Neurodegeneration Caused by Reduction of Psn Expression in the Aging Drosophila Brain. Genetics. 2023-11-23. PMID:37996068. mouse genetic analysis highlighted the importance of presenilin (ps) in learning and memory, synaptic plasticity and neurotransmitter release, and neuronal survival, and drosophila studies further demonstrated an evolutionarily conserved role of ps in neuronal survival during aging. 2023-11-23 2023-11-29 mouse
Niek Brosens, Sylvie L Lesuis, Priyanka Rao-Ruiz, Michel C van den Oever, Harm J Kruger. Shaping memories via stress: a synaptic engram perspective. Biological psychiatry. 2023-11-17. PMID:37977215. at the cellular level, a large body of evidence indicates that (nor)adrenaline and glucocorticoid release induced by acute stress-exposure affects synapse function and synaptic plasticity, which are critical substrates for learning and memory. 2023-11-17 2023-11-20 Not clear
Wenyue Su, Yan Liu, Aileen Lam, Xiaoning Hao, Michel Baudry, Xiaoning B. Contextual fear memory impairment in Angelman syndrome model mice is associated with altered transcriptional responses. Scientific reports. vol 13. issue 1. 2023-10-31. PMID:37903805. unique recall degs in wt mice were enriched in biological processes critical for synaptic plasticity and learning and memory, including the extracellular matrix network clustered around fibronectin 1 and collagens. 2023-10-31 2023-11-08 mouse
Kwan Young Lee, Haohan Wang, Yeeun Yook, Justin S Rhodes, Catherine A Christian-Hinman, Nien-Pei Tsa. Tumor suppressor p53 modulates activity-dependent synapse strengthening, autism-like behavior and hippocampus-dependent learning. Molecular psychiatry. 2023-09-27. PMID:37759036. altogether, our study suggests p53 as an activity-dependent transcription factor that mediates the surface expression of ampar, permits hippocampal synaptic plasticity, represses autism-like behavior, and promotes hippocampus-dependent learning and memory. 2023-09-27 2023-10-07 mouse
Kongjie Lu, Chenyang Li, Jiao Liu, Jinpeng Wang, Yongfeng Li, Bin He, Junzhao Li, Xiaochen Zhang, Mengping Wei, Yonglu Tian, Rong Zhang, Chen Zhang, Yong Zhan. Impairments in endogenous AMPA receptor dynamics correlates with learning deficits in Alzheimer's disease model mice. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 40. 2023-09-25. PMID:37748061. ampa receptors (ampars) play a critical role in synaptic plasticity and learning and memory, and dysfunction or dysregulation of ampars could lead to various neurological and psychiatric disorders, such as alzheimer's disease (ad). 2023-09-25 2023-10-07 mouse
Jie Yuan, Jing Gao, Kai-Qi Su, Xiao-Dong Fen. [Electroacupuncture improves learning and memory impairment and enhances hippocampal synaptic plasticity through BDNF/TRKB/CREB signaling pathway in cerebral ischemia-reperfusion injury rats]. Zhen ci yan jiu = Acupuncture research. vol 48. issue 9. 2023-09-20. PMID:37730254. [electroacupuncture improves learning and memory impairment and enhances hippocampal synaptic plasticity through bdnf/trkb/creb signaling pathway in cerebral ischemia-reperfusion injury rats]. 2023-09-20 2023-10-07 rat
Jie Yuan, Jing Gao, Kai-Qi Su, Xiao-Dong Fen. [Electroacupuncture improves learning and memory impairment and enhances hippocampal synaptic plasticity through BDNF/TRKB/CREB signaling pathway in cerebral ischemia-reperfusion injury rats]. Zhen ci yan jiu = Acupuncture research. vol 48. issue 9. 2023-09-20. PMID:37730254. to observe the effect of electroacupuncture on brain-derived neurotrophin factor (bdnf) / tyrosine kinase receptor b (trkb) / cyclic adenosine monophosphate response element binding protein (creb) pathway, synaptic plasticity marker protein and synaptic ultrastructure in the hippocampus of rats with learning and memory impairment induced by cerebral ischemia reperfusion (ir), so as to explore its mechanisms underlying improvement of cognitive impairment after stroke. 2023-09-20 2023-10-07 rat
Mingcui Luo, Yiwen Yi, Songqiang Huang, Shiyun Dai, Lulu Xie, Kexin Liu, Shuai Zhang, Tao Jiang, Tingting Wang, Baozhen Yao, Hui Wang, Dan X. Gestational dexamethasone exposure impacts hippocampal excitatory synaptic transmission and learning and memory function with transgenerational effects. Acta pharmaceutica Sinica. B. vol 13. issue 9. 2023-09-18. PMID:37719378. the formation of learning and memory is regulated by synaptic plasticity in hippocampal neurons. 2023-09-18 2023-10-07 rat
Mingcui Luo, Yiwen Yi, Songqiang Huang, Shiyun Dai, Lulu Xie, Kexin Liu, Shuai Zhang, Tao Jiang, Tingting Wang, Baozhen Yao, Hui Wang, Dan X. Gestational dexamethasone exposure impacts hippocampal excitatory synaptic transmission and learning and memory function with transgenerational effects. Acta pharmaceutica Sinica. B. vol 13. issue 9. 2023-09-18. PMID:37719378. pde impaired synaptic transmission of hippocampal excitatory neurons in offspring of f1 to f3 generations, and abnormalities of neurotransmitters and receptors would impair synaptic plasticity and lead to impaired learning and memory, but these changes failed to carry over to offspring of f5 and f7 generations. 2023-09-18 2023-10-07 rat
Simone Tambaro, Sumonto Mitra, Ruchi Gera, Bengt Linderoth, Lars U Wahlberg, Taher Darreh-Shori, Homira Behbahani, Per Nilsson, Maria Eriksdotte. Feasibility and therapeutical potential of local intracerebral encapsulated cell biodelivery of BDNF to App Alzheimer's research & therapy. vol 15. issue 1. 2023-08-21. PMID:37596686. brain-derived neurotrophic factor (bdnf) is a key neurotrophin involved in the learning and memory process, with a crucial role in synaptic plasticity and neuronal survival. 2023-08-21 2023-09-07 mouse
Shahin Khodaei, Dian-Shi Wang, Beverley A Orse. Reduced excitatory neurotransmission in the hippocampus after inflammation and sevoflurane anaesthesia. BJA open. vol 6. 2023-08-17. PMID:37588178. synaptic plasticity in the hippocampus, a cellular correlate of learning and memory, was also studied. 2023-08-17 2023-09-07 Not clear