| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J A Hellings, J K Warnoc. Self-injurious behavior and serotonin in Prader-Willi syndrome. Psychopharmacology bulletin. vol 30. issue 2. 1995-02-23. PMID:7831463. |
low central nervous system (cns) serotonin levels have been associated with impulsive, aggressive and self-injurious behavior (sib). |
1995-02-23 |
2023-08-12 |
Not clear |
| F Saudou, D A Amara, A Dierich, M LeMeur, S Ramboz, L Segu, M C Buhot, R He. Enhanced aggressive behavior in mice lacking 5-HT1B receptor. Science (New York, N.Y.). vol 265. issue 5180. 1994-10-19. PMID:8091214. |
the neuromodulator serotonin (5-hydroxytryptamine, 5-ht) has been associated with mood disorders such as depression, anxiety, and impulsive violence. |
1994-10-19 |
2023-08-12 |
mouse |
| U D McCann, A Ridenour, Y Shaham, G A Ricaurt. Serotonin neurotoxicity after (+/-)3,4-methylenedioxymethamphetamine (MDMA; "Ecstasy"): a controlled study in humans. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 10. issue 2. 1994-08-10. PMID:7517677. |
outcome measures obtained after at least 2 weeks of drug abstinence included concentrations of monoamine metabolites in cerebrospinal fluid (csf), prolactin responses to l-tryptophan, nociceptive responses to ischemic pain, and personality characteristics in which 5-ht has been implicated (i.e., impulsivity and aggression). |
1994-08-10 |
2023-08-12 |
human |
| U D McCann, A Ridenour, Y Shaham, G A Ricaurt. Serotonin neurotoxicity after (+/-)3,4-methylenedioxymethamphetamine (MDMA; "Ecstasy"): a controlled study in humans. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 10. issue 2. 1994-08-10. PMID:7517677. |
further, differences in personality support the view that 5-ht systems are involved in modulating impulsive and aggressive personality traits. |
1994-08-10 |
2023-08-12 |
human |
| J G Csernansky, Y I Shelin. Abnormalities of serotonin metabolism and nonpsychotic psychiatric disorders. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists. vol 5. issue 4. 1994-03-23. PMID:8312985. |
abnormalities of brain serotonin (5-hydroxytryptamine; 5-ht) metabolism have been proposed as the neurobiological basis of a vulnerability to depression and of a long-standing tendency toward impulsivity and aggression. |
1994-03-23 |
2023-08-12 |
Not clear |
| J G Csernansky, Y I Shelin. Abnormalities of serotonin metabolism and nonpsychotic psychiatric disorders. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists. vol 5. issue 4. 1994-03-23. PMID:8312985. |
the goal of future research should be to better define the pathophysiological role of 5-ht dysfunction for both mood instability and impulsivity, in the service of developing improved treatments for these psychopathological conditions. |
1994-03-23 |
2023-08-12 |
Not clear |
| M Virkkunen, R Rawlings, R Tokola, R E Poland, A Guidotti, C Nemeroff, G Bissette, K Kalogeras, S L Karonen, M Linnoil. CSF biochemistries, glucose metabolism, and diurnal activity rhythms in alcoholic, violent offenders, fire setters, and healthy volunteers. Archives of general psychiatry. vol 51. issue 1. 1994-02-07. PMID:7506515. |
there is an extensive literature describing a central serotonin deficit in alcoholic, impulsive, violent offenders and fire setters. |
1994-02-07 |
2023-08-12 |
human |
| M Virkkunen, R Rawlings, R Tokola, R E Poland, A Guidotti, C Nemeroff, G Bissette, K Kalogeras, S L Karonen, M Linnoil. CSF biochemistries, glucose metabolism, and diurnal activity rhythms in alcoholic, violent offenders, fire setters, and healthy volunteers. Archives of general psychiatry. vol 51. issue 1. 1994-02-07. PMID:7506515. |
in the present study, we investigated biochemical concomitants of impulsivity and aggressiveness, and the physiological consequences of reduced central serotonin turnover. |
1994-02-07 |
2023-08-12 |
human |
| M Virkkunen, M Linnoil. Brain serotonin, type II alcoholism and impulsive violence. Journal of studies on alcohol. Supplement. vol 11. 1993-11-23. PMID:8410958. |
brain serotonin, type ii alcoholism and impulsive violence. |
1993-11-23 |
2023-08-12 |
human |
| M Candito, F Askenazy, M Myquel, P Chambon, G Darcour. Tryptophanemia and tyrosinemia in adolescents with impulsive behavior. International clinical psychopharmacology. vol 8. issue 2. 1993-09-09. PMID:8345161. |
tryptophan (trp) and tyrosine (tyr), respectively the circulating precursors of the central serotonergic (5-ht) and catecholamine systems, were measured in eight adolescents with impulsive behavior regardless of the exact type of disorder. |
1993-09-09 |
2023-08-12 |
human |
| M Korzekwa, P Links, M Steine. Biological markers in borderline personality disorder: new perspectives. Canadian journal of psychiatry. Revue canadienne de psychiatrie. vol 38 Suppl 1. 1993-04-21. PMID:8453532. |
an extensive analysis of serotonin studies provides exciting new directions for understanding suicidal, aggressive and especially impulsive traits. |
1993-04-21 |
2023-08-12 |
Not clear |
| D J Stein, E Hollander, M R Liebowit. Neurobiology of impulsivity and the impulse control disorders. The Journal of neuropsychiatry and clinical neurosciences. vol 5. issue 1. 1993-03-10. PMID:7679020. |
in particular, they critically review evidence that the serotonin neurotransmitter system mediates symptoms and traits of impulsive personality disorders and the impulse control disorders. |
1993-03-10 |
2023-08-12 |
Not clear |
| S E Mølle. Serotonin, carbohydrates, and atypical depression. Pharmacology & toxicology. vol 71 Suppl 1. 1993-02-11. PMID:1480561. |
central serotonin pathways participate in the regulation of mood and behavioural impulsivity, and modulate eating patterns qualitatively and quantitatively. |
1993-02-11 |
2023-08-11 |
rat |
| E F Coccar. Impulsive aggression and central serotonergic system function in humans: an example of a dimensional brain-behavior relationship. International clinical psychopharmacology. vol 7. issue 1. 1992-08-07. PMID:1624755. |
a dimensional relationship between central serotonergic (5-ht) system function and indices of suicidal and impulsive aggressive behaviors has been suggested by more than a decade of research in patients with psychiatric disorders. |
1992-08-07 |
2023-08-11 |
Not clear |
| E F Coccar. Impulsive aggression and central serotonergic system function in humans: an example of a dimensional brain-behavior relationship. International clinical psychopharmacology. vol 7. issue 1. 1992-08-07. PMID:1624755. |
the results of these studies suggest that reduced overall central 5-ht function in the limbic-hypothalamic system is associated with suicidal and/or impulsive aggressive behaviors in patients with major mood and/or personality disorders and that diminished 5-ht post-synaptic receptor function in this brain region may be an important biological correlate of these behaviors. |
1992-08-07 |
2023-08-11 |
Not clear |
| J J López-Ibo. Masked depression under the light of the new biological and nosological research. L'Encephale. vol 18 Spec No 1. 1992-07-13. PMID:1600902. |
the serotonin involvement in a wide range of conditions (such as depressions and other mood disorders, anxiety disorders, suicidal and aggressive behaviours, impulsive control disorders) has been explained through the common link of serotonin deficiency in disorders and behaviours characterized by a poor control of impulses (multi-impulsive disorders). |
1992-07-13 |
2023-08-11 |
Not clear |
| R N Golden, J H Gilmore, M H Corrigan, R D Ekstrom, B T Knight, J C Garbut. Serotonin, suicide, and aggression: clinical studies. The Journal of clinical psychiatry. vol 52 Suppl. 1992-01-30. PMID:1721619. |
various approaches to the study of 5-ht and aggressive, impulsive behavior, including cerebrospinal fluid studies, investigations of peripheral measures of 5-ht, and neuroendocrine studies utilizing 5-ht probes, are highlighted. |
1992-01-30 |
2023-08-11 |
Not clear |
| J R Cornelius, P H Soloff, J M Perel, R F Ulric. A preliminary trial of fluoxetine in refractory borderline patients. Journal of clinical psychopharmacology. vol 11. issue 2. 1991-08-01. PMID:2056138. |
borderline personality disorder is characterized by many of the symptoms associated with serotonin dysregulation, including affective lability, suicidal behaviors, and impulsive aggression. |
1991-08-01 |
2023-08-11 |
Not clear |
| E F Coccaro, J L Astil. Central serotonergic function in parasuicide. Progress in neuro-psychopharmacology & biological psychiatry. vol 14. issue 5. 1991-04-08. PMID:1981394. |
since reduced central 5-ht activity appears to be consistently associated with impulsive aggression, it is possible that suicidal and parasuicidal acts in individuals with evidence of reduced central 5-ht activity are a manifestation of reduced impulse control. |
1991-04-08 |
2023-08-11 |
Not clear |
| J J Lopez-Ibo. Impulse control in obsessive-compulsive disorder: a biopsychopathological approach. Progress in neuro-psychopharmacology & biological psychiatry. vol 14. issue 5. 1991-04-08. PMID:2293251. |
evidence from biological research and from treatment outcome studies also suggest common traits in the "hyponomic" (impulsive) and "hypernomic" (obsessive) individuals, related to serotonin (5-ht) metabolism disturbances. |
1991-04-08 |
2023-08-11 |
Not clear |