| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hironobu Yoshimatsu, Seiichi Chiba, Daisuke Tajima, Yuko Akehi, Toshiie Sakat. Histidine suppresses food intake through its conversion into neuronal histamine. Experimental biology and medicine (Maywood, N.J.). vol 227. issue 1. 2002-01-30. PMID:11788786. |
hypothalamic neuronal histamine has been shown to regulate feeding behavior and energy metabolism as a target of leptin action in the brain. |
2002-01-30 |
2023-08-12 |
rat |
| Hironobu Yoshimatsu, Seiichi Chiba, Daisuke Tajima, Yuko Akehi, Toshiie Sakat. Histidine suppresses food intake through its conversion into neuronal histamine. Experimental biology and medicine (Maywood, N.J.). vol 227. issue 1. 2002-01-30. PMID:11788786. |
the present study aimed to examine the involvement of l-histidine, a precursor of neuronal histamine, in the regulation of feeding behavior in rats. |
2002-01-30 |
2023-08-12 |
rat |
| Hironobu Yoshimatsu, Seiichi Chiba, Daisuke Tajima, Yuko Akehi, Toshiie Sakat. Histidine suppresses food intake through its conversion into neuronal histamine. Experimental biology and medicine (Maywood, N.J.). vol 227. issue 1. 2002-01-30. PMID:11788786. |
pretreatment of the rats with an ip bolus injection of alpha-fluoromethylhistidine, a suicide inhibitor of a histidine decarboxylase (hdc), at a dosage of 224 micromol/kg blocked the conversion of histidine into histamine and attenuated the suppressive effect of histidine on food intake from 64.2% to 88.1% of the controls (p < 0.05). |
2002-01-30 |
2023-08-12 |
rat |
| Hironobu Yoshimatsu, Seiichi Chiba, Daisuke Tajima, Yuko Akehi, Toshiie Sakat. Histidine suppresses food intake through its conversion into neuronal histamine. Experimental biology and medicine (Maywood, N.J.). vol 227. issue 1. 2002-01-30. PMID:11788786. |
the present findings indicate that l-histidine suppresses food intake through its conversion into histamine in the hypothalamus. |
2002-01-30 |
2023-08-12 |
rat |
| K S Eriksson, O Sergeeva, R E Brown, H L Haa. Orexin/hypocretin excites the histaminergic neurons of the tuberomammillary nucleus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 23. 2002-01-11. PMID:11717361. |
histamine has also been shown to play a role in the regulation of sleep and feeding. |
2002-01-11 |
2023-08-12 |
Not clear |
| L Tuomisto, V Lozeva, A Valjakka, A Leckli. Modifying effects of histamine on circadian rhythms and neuronal excitability. Behavioural brain research. vol 124. issue 2. 2002-01-02. PMID:11640965. |
histamine appears to be necessary for the maintenance of the circadian rhythmicity of the adrenocortical hormone release, locomotor activity and food intake, and the sleep-wakefulness cycle. |
2002-01-02 |
2023-08-12 |
monkey |
| T Morimoto, Y Yamamoto, A Yamatodan. Brain histamine and feeding behavior. Behavioural brain research. vol 124. issue 2. 2002-01-02. PMID:11640967. |
brain histamine and feeding behavior. |
2002-01-02 |
2023-08-12 |
mouse |
| T Morimoto, Y Yamamoto, A Yamatodan. Brain histamine and feeding behavior. Behavioural brain research. vol 124. issue 2. 2002-01-02. PMID:11640967. |
based on the clinical observation that some antidepressants and antipsychotics with antihistaminic activity stimulate food intake and increase body weight, histamine has been thought to be an anorectic agent. |
2002-01-02 |
2023-08-12 |
mouse |
| T Morimoto, Y Yamamoto, A Yamatodan. Brain histamine and feeding behavior. Behavioural brain research. vol 124. issue 2. 2002-01-02. PMID:11640967. |
several lines of evidence suggest that histamine decreases food intake via h(1)-receptors (h1r) at least in the ventromedial hypothalamus or the paraventricular nucleus. |
2002-01-02 |
2023-08-12 |
mouse |
| T Morimoto, Y Yamamoto, A Yamatodan. Brain histamine and feeding behavior. Behavioural brain research. vol 124. issue 2. 2002-01-02. PMID:11640967. |
in regulating food intake, histamine is indicated to functionally associate with neuropeptide y, peptide yy, and bombesin. |
2002-01-02 |
2023-08-12 |
mouse |
| T Morimoto, Y Yamamoto, A Yamatodan. Brain histamine and feeding behavior. Behavioural brain research. vol 124. issue 2. 2002-01-02. PMID:11640967. |
however, the question remained as to why the circadian variation in the level of histamine is inversely correlated to the pattern of feeding. |
2002-01-02 |
2023-08-12 |
mouse |
| A Mollet, T A Lutz, S Meier, T Riediger, P A Rushing, E Scharre. Histamine H1 receptors mediate the anorectic action of the pancreatic hormone amylin. American journal of physiology. Regulatory, integrative and comparative physiology. vol 281. issue 5. 2001-12-04. PMID:11641114. |
the mice were also injected with the h3 antagonist thioperamide (20 mg/kg), which reduces feeding by enhancing the release of endogenous histamine through presynaptic h3 receptors. |
2001-12-04 |
2023-08-12 |
mouse |
| S Meade, D M Denbo. Feeding, drinking, and temperature responses of chickens to intracerebroventricular histamine. Physiology & behavior. vol 73. issue 1-2. 2001-08-09. PMID:11399296. |
feeding, drinking, and temperature responses of chickens to intracerebroventricular histamine. |
2001-08-09 |
2023-08-12 |
Not clear |
| S Attoub, L Moizo, I Sobhani, J P Laigneau, M J Lewin, A Bad. The H3 receptor is involved in cholecystokinin inhibition of food intake in rats. Life sciences. vol 69. issue 4. 2001-07-26. PMID:11459437. |
the maximal feeding inhibitory dose of thioperamide (3 mg.kg i.p) increased by 40% and 22 % (p<0.01 vs saline) brain and stomach histamine contents, respectively. |
2001-07-26 |
2023-08-12 |
rat |
| G A Bra. A concise review on the therapeutics of obesity. Nutrition (Burbank, Los Angeles County, Calif.). vol 16. issue 10. 2001-05-31. PMID:11054601. |
monoamines acting on noradrenergic receptors, serotonin receptors, dopamine receptors, and histamine receptors can reduce food intake. |
2001-05-31 |
2023-08-12 |
human |
| W Langhan. Anorexia of infection: current prospects. Nutrition (Burbank, Los Angeles County, Calif.). vol 16. issue 10. 2001-05-31. PMID:11054606. |
central mediators of the anorexia during infection appear to be neurochemicals involved in the normal control of feeding, such as serotonin, dopamine, histamine, corticotropin releasing factor, neuropeptide y, and alpha-melanocyte-stimulating hormone. |
2001-05-31 |
2023-08-12 |
Not clear |
| T Masaki, H Yoshimatsu, S Chiba, T Watanabe, T Sakat. Central infusion of histamine reduces fat accumulation and upregulates UCP family in leptin-resistant obese mice. Diabetes. vol 50. issue 2. 2001-03-29. PMID:11272150. |
to address this issue, effects of central, chronic treatment with histamine on food intake, adiposity, and energy expenditure were examined using leptin-resistant obese and diabetic mice. |
2001-03-29 |
2023-08-12 |
mouse |
| T Masaki, H Yoshimatsu, S Chiba, T Watanabe, T Sakat. Targeted disruption of histamine H1-receptor attenuates regulatory effects of leptin on feeding, adiposity, and UCP family in mice. Diabetes. vol 50. issue 2. 2001-03-29. PMID:11272151. |
targeted disruption of histamine h1-receptor attenuates regulatory effects of leptin on feeding, adiposity, and ucp family in mice. |
2001-03-29 |
2023-08-12 |
mouse |
| T Masaki, H Yoshimatsu, S Chiba, T Watanabe, T Sakat. Targeted disruption of histamine H1-receptor attenuates regulatory effects of leptin on feeding, adiposity, and UCP family in mice. Diabetes. vol 50. issue 2. 2001-03-29. PMID:11272151. |
histamine neurons are widely distributed in the brain and suppress food intake through the histamine h1 receptor (h1-r) in the hypothalamus. |
2001-03-29 |
2023-08-12 |
mouse |
| T Masaki, H Yoshimatsu, S Chiba, T Watanabe, T Sakat. Targeted disruption of histamine H1-receptor attenuates regulatory effects of leptin on feeding, adiposity, and UCP family in mice. Diabetes. vol 50. issue 2. 2001-03-29. PMID:11272151. |
to examine the role of neuronal histamine in leptin signaling pathways, we investigated the effects of h1-r knockout (h1ko) mice on both food intake and mrna expressions of uncoupling proteins (ucps) as regulated by leptin, and concomitantly on basal changes in both expression of hypothalamic neuropeptides and diet-induced fat deposition in adipose tissues. |
2001-03-29 |
2023-08-12 |
mouse |