| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Koro Gotoh, Takayuki Masaki, Seiichi Chiba, Keiko Higuchi, Tetsuya Kakuma, Hiroyuki Shimizu, Masatomo Mori, Toshiie Sakata, Hironobu Yoshimats. Hypothalamic neuronal histamine signaling in the estrogen deficiency-induced obesity. Journal of neurochemistry. vol 110. issue 6. 2009-09-29. PMID:19619143. |
food intake was measured in rats after the treatment of e2, alpha-fluoromethyl histidine, a specific suicide inhibitor of histidine decarboxylase that depletes hypothalamic neuronal histamine, or crh antagonist. |
2009-09-29 |
2023-08-12 |
mouse |
| Koro Gotoh, Takayuki Masaki, Seiichi Chiba, Keiko Higuchi, Tetsuya Kakuma, Hiroyuki Shimizu, Masatomo Mori, Toshiie Sakata, Hironobu Yoshimats. Hypothalamic neuronal histamine signaling in the estrogen deficiency-induced obesity. Journal of neurochemistry. vol 110. issue 6. 2009-09-29. PMID:19619143. |
we measured food intake and body weight in wild-type mice or mice with targeted disruption of the histamine receptors (h1-r) knockout (h1ko mice). |
2009-09-29 |
2023-08-12 |
mouse |
| Koro Gotoh, Takayuki Masaki, Seiichi Chiba, Keiko Higuchi, Tetsuya Kakuma, Hiroyuki Shimizu, Masatomo Mori, Toshiie Sakata, Hironobu Yoshimats. Hypothalamic neuronal histamine signaling in the estrogen deficiency-induced obesity. Journal of neurochemistry. vol 110. issue 6. 2009-09-29. PMID:19619143. |
ovx increased food intake and body weight, and decreased crh content and histamine turnover in the hypothalamus. |
2009-09-29 |
2023-08-12 |
mouse |
| Koro Gotoh, Takayuki Masaki, Seiichi Chiba, Keiko Higuchi, Tetsuya Kakuma, Hiroyuki Shimizu, Masatomo Mori, Toshiie Sakata, Hironobu Yoshimats. Hypothalamic neuronal histamine signaling in the estrogen deficiency-induced obesity. Journal of neurochemistry. vol 110. issue 6. 2009-09-29. PMID:19619143. |
these results indicate that crh and hypothalamic neuronal histamine mediate the suppressive effects of e2 on feeding behavior and body weight. |
2009-09-29 |
2023-08-12 |
mouse |
| Pascale David Pierson, Alec Fettes, Christian Freichel, Silvia Gatti-McArthur, Cornelia Hertel, Jörg Huwyler, Peter Mohr, Toshito Nakagawa, Matthias Nettekoven, Jean-Marc Plancher, Susanne Raab, Hans Richter, Olivier Roche, Rosa María Rodríguez Sarmiento, Monique Schmitt, Franz Schuler, Tadakatsu Takahashi, Sven Taylor, Christoph Ullmer, Ruby Wiegan. 5-hydroxyindole-2-carboxylic acid amides: novel histamine-3 receptor inverse agonists for the treatment of obesity. Journal of medicinal chemistry. vol 52. issue 13. 2009-08-12. PMID:19456097. |
several pieces of evidence across different species, including primates, underscore the implication of the histamine 3 receptor (h(3)r) in the regulation of food intake and body weight and the potential therapeutic effect of h(3)r inverse agonists. |
2009-08-12 |
2023-08-12 |
human |
| Preeti H Jethwa, Perry Barrett, Yvonne Turnbull, Rachel A Enright, Amy Warner, Michelle Murphy, Francis J P Eblin. The role of histamine 3 receptors in the control of food intake in a seasonal model of obesity: the Siberian hamster. Behavioural pharmacology. vol 20. issue 2. 2009-06-09. PMID:19339875. |
the role of histamine 3 receptors in the control of food intake in a seasonal model of obesity: the siberian hamster. |
2009-06-09 |
2023-08-12 |
Not clear |
| Preeti H Jethwa, Perry Barrett, Yvonne Turnbull, Rachel A Enright, Amy Warner, Michelle Murphy, Francis J P Eblin. The role of histamine 3 receptors in the control of food intake in a seasonal model of obesity: the Siberian hamster. Behavioural pharmacology. vol 20. issue 2. 2009-06-09. PMID:19339875. |
intracerebroventricular administration of histamine decreased food intake in hamsters in the fat summer state. |
2009-06-09 |
2023-08-12 |
Not clear |
| Preeti H Jethwa, Perry Barrett, Yvonne Turnbull, Rachel A Enright, Amy Warner, Michelle Murphy, Francis J P Eblin. The role of histamine 3 receptors in the control of food intake in a seasonal model of obesity: the Siberian hamster. Behavioural pharmacology. vol 20. issue 2. 2009-06-09. PMID:19339875. |
in summary, our results suggest that increased availability of central histamine or the reduction of h3r activity decrease food intake. |
2009-06-09 |
2023-08-12 |
Not clear |
| Seiichi Chiba, Emi Itateyama, Toshiie Sakata, Hironobu Yoshimats. Acute central administration of immepip, a histamine H3 receptor agonist, suppresses hypothalamic histamine release and elicits feeding behavior in rats. Brain research bulletin. vol 79. issue 1. 2009-05-12. PMID:19150394. |
acute central administration of immepip, a histamine h3 receptor agonist, suppresses hypothalamic histamine release and elicits feeding behavior in rats. |
2009-05-12 |
2023-08-12 |
rat |
| Seiichi Chiba, Emi Itateyama, Toshiie Sakata, Hironobu Yoshimats. Acute central administration of immepip, a histamine H3 receptor agonist, suppresses hypothalamic histamine release and elicits feeding behavior in rats. Brain research bulletin. vol 79. issue 1. 2009-05-12. PMID:19150394. |
histamine suppresses feeding behavior via histamine h1 receptors in the hypothalamus. |
2009-05-12 |
2023-08-12 |
rat |
| Seiichi Chiba, Emi Itateyama, Toshiie Sakata, Hironobu Yoshimats. Acute central administration of immepip, a histamine H3 receptor agonist, suppresses hypothalamic histamine release and elicits feeding behavior in rats. Brain research bulletin. vol 79. issue 1. 2009-05-12. PMID:19150394. |
this study was performed to examine whether the acute reduction of histamine release in the hypothalamus caused by immepip, a histamine h3 agonist, modulates the feeding behavior of rats. |
2009-05-12 |
2023-08-12 |
rat |
| Seiichi Chiba, Emi Itateyama, Toshiie Sakata, Hironobu Yoshimats. Acute central administration of immepip, a histamine H3 receptor agonist, suppresses hypothalamic histamine release and elicits feeding behavior in rats. Brain research bulletin. vol 79. issue 1. 2009-05-12. PMID:19150394. |
these results suggest that i3v administration of immepip, an h3 receptor agonist, suppresses hypothalamic histamine release and elicits feeding behavior in rats. |
2009-05-12 |
2023-08-12 |
rat |
| Hironobu Yoshimats. Hypothalamic neuronal histamine regulates body weight through the modulation of diurnal feeding rhythm. Nutrition (Burbank, Los Angeles County, Calif.). vol 24. issue 9. 2009-01-28. PMID:18725079. |
hypothalamic neuronal histamine regulates body weight through the modulation of diurnal feeding rhythm. |
2009-01-28 |
2023-08-12 |
mouse |
| Hironobu Yoshimats. Hypothalamic neuronal histamine regulates body weight through the modulation of diurnal feeding rhythm. Nutrition (Burbank, Los Angeles County, Calif.). vol 24. issue 9. 2009-01-28. PMID:18725079. |
hypothalamic neuronal histamine and its h(1) receptor (h(1)-r), a leptin signaling pathway in the brain, regulate body weight and adiposity by affecting food intake and energy expenditure. |
2009-01-28 |
2023-08-12 |
mouse |
| Hironobu Yoshimats. Hypothalamic neuronal histamine regulates body weight through the modulation of diurnal feeding rhythm. Nutrition (Burbank, Los Angeles County, Calif.). vol 24. issue 9. 2009-01-28. PMID:18725079. |
leptin-induced suppression of food intake and upregulation of uncoupling protein-1 expression in brown adipose tissue were partially attenuated in histamine h(1)-r knockout (h(1)ko) mice. |
2009-01-28 |
2023-08-12 |
mouse |
| Hironobu Yoshimats. Hypothalamic neuronal histamine regulates body weight through the modulation of diurnal feeding rhythm. Nutrition (Burbank, Los Angeles County, Calif.). vol 24. issue 9. 2009-01-28. PMID:18725079. |
these findings suggest that histamine h(1)-r is crucial for regulating the feeding rhythm and in mediating the effects of leptin. |
2009-01-28 |
2023-08-12 |
mouse |
| W A Fogel, A Stasiak, A Lewinski, M Maksymowicz, J Joche. Satiety signalling histaminergic system and brain-gut peptides in regulation of food intake in rats with portocaval anastomosis. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 59 Suppl 2. 2008-12-12. PMID:18812634. |
brain histamine plays a regulatory role in feeding behaviour, acting as an inhibitory modulator. |
2008-12-12 |
2023-08-12 |
rat |
| W A Fogel, A Stasiak, A Lewinski, M Maksymowicz, J Joche. Satiety signalling histaminergic system and brain-gut peptides in regulation of food intake in rats with portocaval anastomosis. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 59 Suppl 2. 2008-12-12. PMID:18812634. |
to disclose underlying regulatory mechanisms, food intake was measured before and after treatment with antagonists of histamine h(1) and h(2), orexin type 1 (ox(1)) and cannabinoid type 1 (cb(1)) receptors in adult male lewis rats 6 months following the end-to-side pca or sham operation. |
2008-12-12 |
2023-08-12 |
rat |
| Zendehdel Morteza, Babapour Vahhab, Jonaidi Hossei. Effects of central histamine receptors blockade on GABA(A) agonist-induced food intake in broiler cockerels. Pakistan journal of biological sciences : PJBS. vol 11. issue 3. 2008-10-16. PMID:18817165. |
effects of central histamine receptors blockade on gaba(a) agonist-induced food intake in broiler cockerels. |
2008-10-16 |
2023-08-12 |
Not clear |
| Nir Bara. Betahistine: what's new on the agenda? Expert opinion on investigational drugs. vol 17. issue 5. 2008-06-02. PMID:18447604. |
in recent years, histamine was found to be a key neurotransmitter in the regulation of feeding behavior. |
2008-06-02 |
2023-08-12 |
Not clear |