| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M L M Rocha, P P Fernandes, B M Lotufo, A C Manhães, P C Barradas, F Tenori. Undernutrition during early life alters neuropeptide Y distribution along the arcuate/paraventricular pathway. Neuroscience. vol 256. 2014-08-27. PMID:24183962. |
feeding behavior is mainly modulated by neural and hormonal inputs to the hypothalamus. |
2014-08-27 |
2023-08-12 |
rat |
| Takashi Sumita, Hiraku Ono, Tokuko Suzuki, Gota Sakai, Kouichi Inukai, Hideki Katagiri, Tomoichiro Asano, Shigehiro Katayama, Takuya Awat. Mediobasal hypothalamic PTEN modulates hepatic insulin resistance independently of food intake in rats. American journal of physiology. Endocrinology and metabolism. vol 307. issue 1. 2014-08-27. PMID:24824654. |
insulin acts in the mediobasal hypothalamus (mbh) to not only suppress food intake and weight gain but also improve glucose metabolism via pi 3-kinase activation. |
2014-08-27 |
2023-08-13 |
rat |
| Xavier Brenachot, Caroline Rigault, Emmanuelle Nédélec, Amélie Laderrière, Tasneem Khanam, Alexandra Gouazé, Sylvie Chaudy, Aleth Lemoine, Frédérique Datiche, Jean Gascuel, Luc Pénicaud, Alexandre Benan. The histone acetyltransferase MOF activates hypothalamic polysialylation to prevent diet-induced obesity in mice. Molecular metabolism. vol 3. issue 6. 2014-08-27. PMID:25161885. |
overfeeding causes rapid synaptic remodeling in hypothalamus feeding circuits. |
2014-08-27 |
2023-08-13 |
mouse |
| Xavier Brenachot, Caroline Rigault, Emmanuelle Nédélec, Amélie Laderrière, Tasneem Khanam, Alexandra Gouazé, Sylvie Chaudy, Aleth Lemoine, Frédérique Datiche, Jean Gascuel, Luc Pénicaud, Alexandre Benan. The histone acetyltransferase MOF activates hypothalamic polysialylation to prevent diet-induced obesity in mice. Molecular metabolism. vol 3. issue 6. 2014-08-27. PMID:25161885. |
mof silencing in the mediobasal hypothalamus of adult mice prevented activation of the st8sia4 gene transcription, reduced polysialylation, altered the acute homeostatic feeding response to hfd and increased the body weight gain. |
2014-08-27 |
2023-08-13 |
mouse |
| Alexander V Loktev, Peter K Jackso. Neuropeptide Y family receptors traffic via the Bardet-Biedl syndrome pathway to signal in neuronal primary cilia. Cell reports. vol 5. issue 5. 2014-08-26. PMID:24316073. |
we show that mice modeling bbs disease or obese tubby mice fail to localize npy2r to cilia in the hypothalamus and that bbs mutant mice fail to activate c-fos or decrease food intake in response to the npy2r ligand pyy3-36. |
2014-08-26 |
2023-08-12 |
mouse |
| Jing Dong, Huan Xu, Huan Xu, Peng-fei Wang, Gui-ju Cai, Hai-feng Song, Chang-chen Wang, Zhao-tong Dong, Yan-jiao Ju, Zheng-yao Jian. Nesfatin-1 stimulates fatty-acid oxidation by activating AMP-activated protein kinase in STZ-induced type 2 diabetic mice. PloS one. vol 8. issue 12. 2014-08-25. PMID:24391760. |
we observed that plasma nesfatin-1 was significantly increased while expression of nesfatin-1 neurons were decreased in hypothalamus in diabetes group compared to only high-calorie diet control group; intravenous injection of nesfatin-1 decreased 0-1h, 0-2h, 0-3h cumulative food intake in t2dm, but 0-24h total food intake had no difference between groups. |
2014-08-25 |
2023-08-12 |
mouse |
| Maria A Agapito, Changqing Zhang, Sengottuvelan Murugan, Dipak K Sarka. Fetal alcohol exposure disrupts metabolic signaling in hypothalamic proopiomelanocortin neurons via a circadian mechanism in male mice. Endocrinology. vol 155. issue 7. 2014-08-25. PMID:24797626. |
early-life ethanol feeding (elaf) alters the metabolic function of proopiomelanocortin (pomc)-producing neurons and the circadian expression of clock regulatory genes in the hypothalamus. |
2014-08-25 |
2023-08-13 |
mouse |
| Bruno Chausse, Carina Solon, Camille C Caldeira da Silva, Ivan G Masselli Dos Reis, Fúlvia B Manchado-Gobatto, Claudio A Gobatto, Licio A Velloso, Alicia J Kowaltowsk. Intermittent fasting induces hypothalamic modifications resulting in low feeding efficiency, low body mass and overeating. Endocrinology. vol 155. issue 7. 2014-08-25. PMID:24797627. |
furthermore, an increased expression of orexigenic neurotransmitters agrp and npy in the hypothalamus of if animals was found, even on feeding days, which could explain the overeating pattern. |
2014-08-25 |
2023-08-13 |
rat |
| I M Szeto, M E Payne, A Jahan-Mihan, J Duan, G H Anderso. Multivitamin supplementation during pregnancy alters body weight and macronutrient selection in Wistar rat offspring. Journal of developmental origins of health and disease. vol 1. issue 6. 2014-08-22. PMID:25142010. |
the hypothesis that vitamin content of the diet during gestation alters macronutrient choice, food intake and the expression of serotonin receptors and proopiomelanocortin (pomc) in the hypothalamus of the offspring was investigated. |
2014-08-22 |
2023-08-13 |
rat |
| I M Szeto, M E Payne, A Jahan-Mihan, J Duan, G H Anderso. Multivitamin supplementation during pregnancy alters body weight and macronutrient selection in Wistar rat offspring. Journal of developmental origins of health and disease. vol 1. issue 6. 2014-08-22. PMID:25142010. |
in conclusion, intake of multivitamins above the requirements during pregnancy affected macronutrient choice, food intake and the expression of serotonin receptors and pomc in the hypothalamus. |
2014-08-22 |
2023-08-13 |
rat |
| Vanessa V Dos Santos, Ana Lúcia S Rodrigues, Thereza C De Lima, Susana R de Barioglio, Rita Raisman-Vozari, Rui D Predige. Ghrelin as a neuroprotective and palliative agent in Alzheimer's and Parkinson's disease. Current pharmaceutical design. vol 19. issue 38. 2014-08-21. PMID:23530516. |
ghrelin is a gastric hormone that stimulates growth hormone (gh) secretion and food intake to regulate energy homeostasis and body weight by binding to its receptor, gh secretagogue receptor (ghsr1a), which is most highly expressed in the pituitary and hypothalamus. |
2014-08-21 |
2023-08-12 |
Not clear |
| Wanchun Yang, Wanxiang Jiang, Liping Luo, Jicheng Bu, Dejiang Pang, Jing Wei, Chongyangzi Du, Xiaoqiang Xia, Yiyuan Cui, Shuang Liu, Qing Mao, Mina Che. Genetic deletion of Rheb1 in the brain reduces food intake and causes hypoglycemia with altered peripheral metabolism. International journal of molecular sciences. vol 15. issue 1. 2014-08-19. PMID:24451134. |
the hypothalamus in the brain plays a critical role in the control of food intake and peripheral metabolism. |
2014-08-19 |
2023-08-12 |
mouse |
| S D Primeaux, M J Barnes, H D Brayme. Hypothalamic QRFP: regulation of food intake and fat selection. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 45. issue 13. 2014-08-18. PMID:23979792. |
prepro-qrfp mrna expression is localized to select regions of the hypothalamus, which are involved in the regulation of feeding behavior. |
2014-08-18 |
2023-08-12 |
mouse |
| b' A Stengel, Y Tach\\xc3\\xa. Role of NUCB2/Nesfatin-1 in the hypothalamic control of energy homeostasis. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 45. issue 13. 2014-08-18. PMID:24048879.' |
within the brain, the hypothalamus plays a pivotal role as a production site of food intake regulatory factors. |
2014-08-18 |
2023-08-12 |
rat |
| b' A Stengel, Y Tach\\xc3\\xa. Role of NUCB2/Nesfatin-1 in the hypothalamic control of energy homeostasis. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 45. issue 13. 2014-08-18. PMID:24048879.' |
of interest was the demonstration that nucb2 also exerts its anorexigenic action in the paraventricular nucleus of the hypothalamus and is regulated at this site by changes in metabolic status with a diurnal rhythm inversely related to that of feeding in rats. |
2014-08-18 |
2023-08-12 |
rat |
| Adrián Báez-Ruiz, Dalia Luna-Moreno, Agustín Carmona-Castro, René Cárdenas-Vázquez, Mauricio Díaz-Muñoz, Vania Carmona-Alcocer, Citlalli Fuentes-Granados, Miranda-Anaya Manue. Hypothalamic expression of anorexigenic and orexigenic hormone receptors in obese females Neotomodon alstoni: effect of fasting. Nutritional neuroscience. vol 17. issue 1. 2014-08-15. PMID:24401125. |
obesity is a world problem that requires a better understanding of its physiological and genetic basis, as well as the mechanisms by which the hypothalamus controls feeding behavior. |
2014-08-15 |
2023-08-12 |
mouse |
| Su Gao, Timothy H Moran, Gary D Lopaschuk, Andrew A Butle. Hypothalamic malonyl-CoA and the control of food intake. Physiology & behavior. vol 122. 2014-08-11. PMID:23988346. |
malonyl-coa in the hypothalamus has been proposed as an anorectic mediator in the central control of feeding. |
2014-08-11 |
2023-08-12 |
Not clear |
| Andrew J Irving, Jenni Harve. Leptin regulation of hippocampal synaptic function in health and disease. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 369. issue 1633. 2014-08-11. PMID:24298156. |
the endocrine hormone leptin plays a key role in regulating food intake and body weight via its actions in the hypothalamus. |
2014-08-11 |
2023-08-12 |
Not clear |
| Hirotaka Ueda, Takakazu Yagi, Haruka Amitani, Akihiro Asakawa, Satoshi Ikeda, Shouichi Miyawaki, Akio Inu. The roles of salivary secretion, brain-gut peptides, and oral hygiene in obesity. Obesity research & clinical practice. vol 7. issue 5. 2014-07-28. PMID:24455760. |
leptin is an adipostatic hormone that acts on receptors in the hypothalamus to suppress food intake and increase energy consumption. |
2014-07-28 |
2023-08-12 |
Not clear |
| Edyta Adamska, Lucyna Ostrowska, Maria Górska, Adam Krętowsk. The role of gastrointestinal hormones in the pathogenesis of obesity and type 2 diabetes. Przeglad gastroenterologiczny. vol 9. issue 2. 2014-07-25. PMID:25061485. |
changes in circulating gut hormones concentrations result in activation of various pathways primarily within the hypothalamus and brain stem areas, which modulate feeding behaviour and a number of metabolic processes. |
2014-07-25 |
2023-08-13 |
Not clear |