| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hélène Volkof. In vitro assessment of interactions between appetite-regulating peptides in brain of goldfish (Carassius auratus). Peptides. vol 61. 2015-07-29. PMID:25219945. |
in order to better understand the interactions between appetite-related peptides, the effects of in vitro treatments of hindbrain, forebrain and hypothalamus--a major feeding regulating area--fragments with mch, apelin and orexin on the expression of mch, apelin, orexin, cart (forms 1 and 2) and npy were assessed. |
2015-07-29 |
2023-08-13 |
Not clear |
| Sofia Nasif, Flavio S J de Souza, Laura E González, Miho Yamashita, Daniela P Orquera, Malcolm J Low, Marcelo Rubinstei. Islet 1 specifies the identity of hypothalamic melanocortin neurons and is critical for normal food intake and adiposity in adulthood. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 15. 2015-07-24. PMID:25825735. |
food intake and body weight regulation depend on proper expression of the proopiomelanocortin gene (pomc) in a group of neurons located in the mediobasal hypothalamus of all vertebrates. |
2015-07-24 |
2023-08-13 |
mouse |
| Britt-Marie Iresjö, Wenhua Wang, Camilla Nilsberth, Marianne Andersson, Christina Lönnroth, Ulrika Smed. Food intake, tumor growth, and weight loss in EP2 receptor subtype knockout mice bearing PGE2-producing tumors. Physiological reports. vol 3. issue 7. 2015-07-22. PMID:26197930. |
prostaglandin d2 synthase levels were increased significantly in ep2 receptor knockouts, suggesting that improved food intake may depend on altered balance of prostaglandin production in hypothalamus since pge2 and pgd2 display opposing effects in feeding control. |
2015-07-22 |
2023-08-13 |
mouse |
| Mona A Abraham, Beatrice M Filippi, Gil Myoung Kang, Min-Seon Kim, Tony K T La. Insulin action in the hypothalamus and dorsal vagal complex. Experimental physiology. vol 99. issue 9. 2015-07-02. PMID:24972836. |
in addition to the classical view that insulin resistance in the liver, muscle and fat disrupts glucose homeostasis, studies in the past decade have illustrated that insulin resistance in the hypothalamus dysregulates hepatic glucose production and food intake, leading to type 2 diabetes and obesity. |
2015-07-02 |
2023-08-13 |
Not clear |
| Mona A Abraham, Beatrice M Filippi, Gil Myoung Kang, Min-Seon Kim, Tony K T La. Insulin action in the hypothalamus and dorsal vagal complex. Experimental physiology. vol 99. issue 9. 2015-07-02. PMID:24972836. |
this invited review argues that in addition to the hypothalamus, insulin signalling in the dorsal vagal complex regulates hepatic glucose production and food intake. |
2015-07-02 |
2023-08-13 |
Not clear |
| Katie Sokolowski, Shigeyuki Esumi, Tsutomu Hirata, Yasman Kamal, Tuyen Tran, Andrew Lam, Livio Oboti, Sherri-Chanelle Brighthaupt, Manar Zaghlula, Jennifer Martinez, Svetlana Ghimbovschi, Susan Knoblach, Alessandra Pierani, Nobuaki Tamamaki, Nirao M Shah, Kevin S Jones, Joshua G Corbi. Specification of select hypothalamic circuits and innate behaviors by the embryonic patterning gene dbx1. Neuron. vol 86. issue 2. 2015-06-30. PMID:25864637. |
the hypothalamus integrates information required for the production of a variety of innate behaviors such as feeding, mating, aggression, and predator avoidance. |
2015-06-30 |
2023-08-13 |
mouse |
| Maegan L Askew, Halie D Muckelrath, Jonathon R Johnston, Kathleen S Curti. Neuroanatomical association of hypothalamic HSD2-containing neurons with ERα, catecholamines, or oxytocin: implications for feeding? Frontiers in systems neuroscience. vol 9. 2015-06-30. PMID:26124709. |
thus, these studies do not conclusively identify a neuroanatomical substrate by which hsd2-containing neurons in the hypothalamus may alter feeding, and leave the functional role of hypothalamic hsd2-containing neurons subject to further investigation. |
2015-06-30 |
2023-08-13 |
human |
| Hellen Barbosa Farias Silva, Ana Paula Carli de Almeida, Katarine Barbosa Cardoso, Letícia Martins Ignacio-Souza, Silvia Regina de Lima Reis, Marise Auxiliadora de Barros Reis, Márcia Queiroz Latorraca, Marciane Milanski, Vanessa Cristina Arante. Nutritional recovery promotes hypothalamic inflammation in rats during adulthood. Mediators of inflammation. vol 2014. 2015-06-24. PMID:25258479. |
we evaluated whether protein restriction in fetal life alters food intake and glucose homeostasis in adulthood by interfering with insulin signal transduction through proinflammatory mechanisms in the hypothalamus and peripheral tissues. |
2015-06-24 |
2023-08-13 |
rat |
| I S de Andrade, J C S Zemdegs, A P de Souza, R L H Watanabe, M M Telles, C M O Nascimento, L M Oyama, E B Ribeir. Diet-induced obesity impairs hypothalamic glucose sensing but not glucose hypothalamic extracellular levels, as measured by microdialysis. Nutrition & diabetes. vol 5. 2015-06-16. PMID:26075639. |
we hypothesized that glucose transport to the hypothalamus as well as glucose sensing and signaling could be impaired by high-fat feeding. |
2015-06-16 |
2023-08-13 |
Not clear |
| Chisayo Kozuka, Sumito Sunagawa, Rei Ueda, Moritake Higa, Hideaki Tanaka, Chigusa Shimizu-Okabe, Shogo Ishiuchi, Chitoshi Takayama, Masayuki Matsushita, Masato Tsutsui, Jun-ichi Miyazaki, Seiichi Oyadomari, Michio Shimabukuro, Hiroaki Masuzak. γ-Oryzanol protects pancreatic β-cells against endoplasmic reticulum stress in male mice. Endocrinology. vol 156. issue 4. 2015-06-11. PMID:25594697. |
our recent study in mice showed that γ-oryzanol, a unique component of brown rice, acts as a chemical chaperone in the hypothalamus and improves feeding behavior and diet-induced dysmetabolism. |
2015-06-11 |
2023-08-13 |
mouse |
| Jörgen A Engel, Elisabet Jerlha. Role of appetite-regulating peptides in the pathophysiology of addiction: implications for pharmacotherapy. CNS drugs. vol 28. issue 10. 2015-06-04. PMID:24958205. |
this gut-brain hormone reduces food intake as well as regulates glucose homeostasis, foremost via glp-1 receptors in hypothalamus and brain stem. |
2015-06-04 |
2023-08-13 |
human |
| A W Smith, O K Rønnekleiv, M J Kell. Gq-mER signaling has opposite effects on hypothalamic orexigenic and anorexigenic neurons. Steroids. vol 81. 2015-05-26. PMID:24269736. |
two populations of cells within the hypothalamus exert opposite actions on food intake: proopiomelanocortin (pomc) neurons decrease it, while neuropeptide y (npy)/agouti-related peptide (agrp) neurons increase it. |
2015-05-26 |
2023-08-12 |
Not clear |
| Anna M van Opstal, Anna M Westerink, Wouter M Teeuwisse, Mirjam A M van der Geest, Eric F van Furth, Jeroen van der Gron. Hypothalamic BOLD response to glucose intake and hypothalamic volume are similar in anorexia nervosa and healthy control subjects. Frontiers in neuroscience. vol 9. 2015-05-22. PMID:25999808. |
the hypothalamus plays a key role in the neurobiological processes that govern food intake and energy homeostasis, processes that are disturbed in anorexia nervosa (an). |
2015-05-22 |
2023-08-13 |
human |
| Anika M Toorie, Eduardo A Nilln. Minireview: Central Sirt1 regulates energy balance via the melanocortin system and alternate pathways. Molecular endocrinology (Baltimore, Md.). vol 28. issue 9. 2015-05-18. PMID:24947673. |
two key energy/nutrient sensors, mammalian target of rapamycin and amp-activated kinase, are involved in the control of food intake in the hypothalamus as well as in peripheral tissues ( 2 , 3 ). |
2015-05-18 |
2023-08-13 |
Not clear |
| Keisuke Okutsu, Fumiya Ojima, Naoto Shinohara, Shusuke Taniuchi, Yasusyo Mizote, Kenji Aoki, Toshiyuki Kudo, Maho Ogoshi, Sakae Takeuchi, Sumio Takahash. Functional characterization of the mouse melanocortin 3 receptor gene promoter. Gene. vol 562. issue 1. 2015-05-15. PMID:25701401. |
melanocortin receptor 3 (mc3r) is expressed in the hypothalamus and pituitary in humans and rodents, and is involved in the control of feeding, energy metabolism, and pituitary function. |
2015-05-15 |
2023-08-13 |
mouse |
| Patricia I M Silva, Catarina I M Martins, Erik Höglund, Hans Magnus Gjøen, Øyvind Øverl. Feeding motivation as a personality trait in Nile tilapia (Oreochromis niloticus): role of serotonergic neurotransmission. Fish physiology and biochemistry. vol 40. issue 5. 2015-05-14. PMID:24858238. |
furthermore, low serotonergic activity in the hypothalamus was highly correlated with a personality characterized by high feeding motivation, with feeding motivation represented as an overall measure incorporating several behavioural parameters in a principle component analyses (pca). |
2015-05-14 |
2023-08-13 |
Not clear |
| Biljana N Bursać, Ana D Vasiljević, Nataša M Nestorović, Nataša A Veličković, Danijela D Vojnović Milutinović, Gordana M Matić, Ana D Djordjevi. High-fructose diet leads to visceral adiposity and hypothalamic leptin resistance in male rats--do glucocorticoids play a role? The Journal of nutritional biochemistry. vol 25. issue 4. 2015-05-12. PMID:24565674. |
hypothalamus and adipose tissue, major organs for control of food intake and energy metabolism, play crucial roles in metabolic homeostasis. |
2015-05-12 |
2023-08-12 |
rat |
| Luigia Cristino, Thorsten Becker, Vincenzo Di Marz. Endocannabinoids and energy homeostasis: an update. BioFactors (Oxford, England). vol 40. issue 4. 2015-05-12. PMID:24752980. |
this review highlights established and more recent data on the brain circuits in which the ecs plays an important regulatory role, with focus on the hypothalamus, a region where numerous interacting systems regulating feeding, satiety, stress, and other motivational states coexist. |
2015-05-12 |
2023-08-13 |
Not clear |
| Yusaku Iwasaki, Yuko Maejima, Shigetomo Suyama, Masashi Yoshida, Takeshi Arai, Kenichi Katsurada, Parmila Kumari, Hajime Nakabayashi, Masafumi Kakei, Toshihiko Yad. Peripheral oxytocin activates vagal afferent neurons to suppress feeding in normal and leptin-resistant mice: a route for ameliorating hyperphagia and obesity. American journal of physiology. Regulatory, integrative and comparative physiology. vol 308. issue 5. 2015-04-29. PMID:25540101. |
oxytocin (oxt), a neuropeptide produced in the hypothalamus, is implicated in regulation of feeding. |
2015-04-29 |
2023-08-13 |
mouse |
| Randy J Seeley, Kent C Berridg. The hunger games. Cell. vol 160. issue 5. 2015-04-29. PMID:25723156. |
although agrp and pomc neurons in the hypothalamus have long been associated with regulation of food intake, in this issue of cell, chen et al. |
2015-04-29 |
2023-08-13 |
Not clear |