| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hale Z Toklu, Philip J Scarpace, Yasemin Sakarya, Nataliya Kirichenko, Michael Matheny, Erin B Bruce, Christy S Carter, Drake Morgan, Nihal Tüme. Intracerebroventricular tempol administration in older rats reduces oxidative stress in the hypothalamus but does not change STAT3 signalling or SIRT1/AMPK pathway. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. vol 42. issue 1. 2017-01-25. PMID:28006433. |
tempol significantly decreased (p < 0.01) nicotinamide adenine dinucleotide phosphate oxidase activity in the hypothalamus but failed to reduce food intake or weight gain and did not alter body composition. |
2017-01-25 |
2023-08-13 |
rat |
| Yue Che. Regulation of food intake and the development of anti-obesity drugs. Drug discoveries & therapeutics. vol 10. issue 2. 2017-01-24. PMID:27063550. |
this article summarizes the feeding control circuits and regulators involved in obesity development, highlight the hypothalamus, melanocortin system and brain-gut peptide actions in this process, and the five us fda approved anti-obesity medications in long term use, namely phentermine/topiramate, lorcaserin, naltrexone/bupropion, liraglutide and orlistat. |
2017-01-24 |
2023-08-13 |
Not clear |
| Aysel Vehapoğlu, Serdar Türkmen, Şule Terzioğl. Alpha-Melanocyte-Stimulating Hormone and Agouti-Related Protein: Do They Play a Role in Appetite Regulation in Childhood Obesity? Journal of clinical research in pediatric endocrinology. vol 8. issue 1. 2017-01-09. PMID:26758700. |
the hypothalamus plays a crucial role in the regulation of feeding behavior. |
2017-01-09 |
2023-08-13 |
Not clear |
| Jorge J Pérez-Maceira, Cristina Otero-Rodiño, María J Mancebo, José L Soengas, Manuel Aldegund. Food intake inhibition in rainbow trout induced by activation of serotonin 5-HT2C receptors is associated with increases in POMC, CART and CRF mRNA abundance in hypothalamus. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology. vol 186. issue 3. 2017-01-05. PMID:26832922. |
food intake inhibition in rainbow trout induced by activation of serotonin 5-ht2c receptors is associated with increases in pomc, cart and crf mrna abundance in hypothalamus. |
2017-01-05 |
2023-08-13 |
Not clear |
| V W W Tsai, S Lin, D A Brown, A Salis, S N Brei. Anorexia-cachexia and obesity treatment may be two sides of the same coin: role of the TGF-b superfamily cytokine MIC-1/GDF15. International journal of obesity (2005). vol 40. issue 2. 2016-12-28. PMID:26620888. |
this cytokine acts on feeding centres in the hypothalamus and brainstem to cause anorexia leading to loss of lean and fat mass and eventually cachexia. |
2016-12-28 |
2023-08-13 |
Not clear |
| C A Woods, Z R Guttman, D Huang, R A Kolaric, A I Rabinowitsch, K T Jones, S Cabeza de Vaca, A Sclafani, K D Car. Insulin receptor activation in the nucleus accumbens reflects nutritive value of a recently ingested meal. Physiology & behavior. vol 159. 2016-12-27. PMID:26988281. |
with respect to feeding, insulin is typically thought of as a satiety hormone, acting in the hypothalamus to limit ingestive behavior. |
2016-12-27 |
2023-08-13 |
rat |
| E Gjerde, H Long, D Richard, C-D Walke. Developmental Responses of the Lateral Hypothalamus to Leptin in Neonatal Rats, and its Implications for the Development of Functional Connections with the Ventral Tegmental Area. Journal of neuroendocrinology. vol 28. issue 3. 2016-12-23. PMID:26709016. |
food intake is regulated by a close communication between the hypothalamus and the mesocorticolimbic pathways, which are still developing during the perinatal period in the rat, and are known targets for peripheral metabolic hormones such as leptin. |
2016-12-23 |
2023-08-13 |
rat |
| G Helfer, A Tup. Hypothalamic Wnt Signalling and its Role in Energy Balance Regulation. Journal of neuroendocrinology. vol 28. issue 3. 2016-12-23. PMID:26802435. |
based on scattered findings that report the presence of wnt molecules in the tanycytes and ependymal cells lining the third ventricle and arcuate nucleus neurones of the hypothalamus, their potential importance in key regions of food intake and body weight regulation has been investigated in recent studies. |
2016-12-23 |
2023-08-13 |
mouse |
| G Helfer, A Tup. Hypothalamic Wnt Signalling and its Role in Energy Balance Regulation. Journal of neuroendocrinology. vol 28. issue 3. 2016-12-23. PMID:26802435. |
aspects of wnt signalling in seasonal (photoperiod sensitive) rodents are also highlighted, given the recent evidence indicating that the wnt pathway in the hypothalamus is not only regulated by diet and leptin, but also by photoperiod in seasonal animals, which is connected to natural adaptive changes in food intake and body weight. |
2016-12-23 |
2023-08-13 |
mouse |
| Shigetomo Suyama, Misato Kodaira-Hirano, Zesemdorj Otgon-Uul, Yoichi Ueta, Masanori Nakata, Toshihiko Yad. Fasted/fed states regulate postsynaptic hub protein DYNLL2 and glutamatergic transmission in oxytocin neurons in the hypothalamic paraventricular nucleus. Neuropeptides. vol 56. 2016-12-21. PMID:26344333. |
the neurons in the hypothalamus regulate food intake and energy metabolism on reception of systemic energy states. |
2016-12-21 |
2023-08-13 |
Not clear |
| Leigh Wellhauser, Jennifer A Chalmers, Denise D Belsha. Nitric Oxide Exerts Basal and Insulin-Dependent Anorexigenic Actions in POMC Hypothalamic Neurons. Molecular endocrinology (Baltimore, Md.). vol 30. issue 4. 2016-12-21. PMID:26930171. |
the arcuate nucleus of the hypothalamus represents a key center for the control of appetite and feeding through the regulation of 2 key neuronal populations, notably agouti-related peptide/neuropeptide y and proopimelanocortin (pomc)/cocaine- and amphetamine-regulated transcript neurons. |
2016-12-21 |
2023-08-13 |
Not clear |
| Florian Reichmann, Peter Holze. Neuropeptide Y: A stressful review. Neuropeptides. vol 55. 2016-12-15. PMID:26441327. |
npy is expressed in particular neurons of the brainstem, hypothalamus and limbic system, which explains why npy has an impact on stress-related changes in emotional-affective behaviour and feeding as well as on stress coping. |
2016-12-15 |
2023-08-13 |
Not clear |
| Rhanor Gillette, Jeffrey W Brow. The Sea Slug, Pleurobranchaea californica: A Signpost Species in the Evolution of Complex Nervous Systems and Behavior. Integrative and comparative biology. vol 55. issue 6. 2016-12-13. PMID:26163678. |
functions of hypothalamus and basal ganglia are combined in pleurobranchaea's feeding motor network. |
2016-12-13 |
2023-08-13 |
Not clear |
| Rhanor Gillette, Jeffrey W Brow. The Sea Slug, Pleurobranchaea californica: A Signpost Species in the Evolution of Complex Nervous Systems and Behavior. Integrative and comparative biology. vol 55. issue 6. 2016-12-13. PMID:26163678. |
they suggest (1) an origin of olfactory bulb and pallium from head-region pns; (2) modularization of an ancestral feeding network into discrete but interacting executive modules for incentive comparison and decision (basal ganglia), and homeostatic functions (hypothalamus); (3) modification of a multifunctional premotor network for turns and locomotion, and its downstream targets for mid-brain and hind-brain motor areas and spinal cpgs; (4) condensation of a distributed serotonergic network for arousal into the raphe nuclei, with superimposed control by a peptidergic hypothalamic network mediating appetite and arousal; (5) centralization and condensation of the dopaminergic sensory afferents of the pns, and/or the disperse dopaminergic elements of central cpgs, into the brain nuclei mediating valuation, reward, and motor arousal; and (6) the urbilaterian possessed the basic circuit relations integrating sensation, internal state, and learning for cost-benefit approach-avoidance decisions. |
2016-12-13 |
2023-08-13 |
Not clear |
| b' Giuseppe Montalbano, Manuela Mania, Maria Cristina Guerrera, Francesco Abbate, Rosaria Laur\\xc3\\xa0, Michele Navarra, Jose A Vega, Emilia Ciriaco, Antonino German\\xc3\\xa. Morphological differences in adipose tissue and changes in BDNF/Trkb expression in brain and gut of a diet induced obese zebrafish model. Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. vol 204. 2016-12-13. PMID:26617157.' |
moreover, various nuclei of the hypothalamus receive and process peripheral stimuli from the gastrointestinal tract, controlling food intake and therefore energy balance. |
2016-12-13 |
2023-08-13 |
zebrafish |
| C Ardianto, N Yonemochi, S Yamamoto, L Yang, F Takenoya, S Shioda, H Nagase, H Ikeda, J Kame. Opioid systems in the lateral hypothalamus regulate feeding behavior through orexin and GABA neurons. Neuroscience. vol 320. 2016-12-13. PMID:26855191. |
the hypothalamus controls feeding behavior. |
2016-12-13 |
2023-08-13 |
mouse |
| Bing Li, Yuemei Xu, Danqing Pan, Qian Xiao, Qi Gao, Xin Chen, Xiuhua Peng, Yuling Du, Pengfei Ga. Effect of immobilization stress on the appetite and stomach ghrelin expression in maternal mice. International journal of clinical and experimental pathology. vol 8. issue 12. 2016-12-13. PMID:26884874. |
the central regulation of body weight and food intake occurs in the hypothalamus, which contains multiple neuronal systems that play important roles in the regulation of energy homeostasis. |
2016-12-13 |
2023-08-13 |
mouse |
| Christophe Magnan, Serge Luque. [Role of fatty acids in the nervous control of energy balance]. Biologie aujourd'hui. vol 209. issue 4. 2016-12-13. PMID:27021049. |
fatty acid (fa)-sensitive neurons are present in the brain, especially the hypothalamus, and play a key role in the neural control of energy and glucose homeostasis including feeding behavior, insulin secretion and action. |
2016-12-13 |
2023-08-13 |
human |
| Ayelén M Blanco, Juan I Bertucci, María J Delgado, Ana I Valenciano, Suraj Unniappa. Tissue-specific expression of ghrelinergic and NUCB2/nesfatin-1 systems in goldfish (Carassius auratus) is modulated by macronutrient composition of diets. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 195. 2016-11-11. PMID:26805937. |
short-term feeding with fat-enriched diets significantly increased nucb2 mrna levels in hypothalamus and liver, preproghrelin, goat and ghs-r1 expression in pituitary, and ghs-r1 expression in gut. |
2016-11-11 |
2023-08-13 |
Not clear |
| Raj K Nangunoori, Nestor D Tomycz, Michael Y Oh, Donald M Whitin. Deep Brain Stimulation for Obesity: From a Theoretical Framework to Practical Application. Neural plasticity. vol 2016. 2016-11-04. PMID:26819774. |
in this review, the authors will review some of the work relating to feeding physiology and research surrounding two nodes involved in feeding homeostasis, nucleus accumbens (nac) and hypothalamus, and use this to provide a framework for future investigations of dbs as a viable therapeutic modality for obesity. |
2016-11-04 |
2023-08-13 |
human |