| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K R Upton, L G Rile. Acute stress inhibits food intake and alters ghrelin signaling in the brain of tilapia (Oreochromis mossambicus). Domestic animal endocrinology. vol 44. issue 3. 2013-09-03. PMID:23291012. |
it is not clear if these changes result in altered feeding behavior because no changes in crh or npy mrna expression were observed or if ghrelin is playing a role in regulating overall metabolic changes after acute stress. |
2013-09-03 |
2023-08-12 |
Not clear |
| Nobuko Sakurazawa, Asuka Mano-Otagiri, Takahiro Nemoto, Tamotsu Shibasak. Effects of intracerebroventricular ghrelin on food intake and Fos expression in the arcuate nucleus of the hypothalamus in female rats vary with estrous cycle phase. Neuroscience letters. vol 541. 2013-09-03. PMID:23435434. |
intracerebroventricular (icv) injection of ghrelin increases food intake via activation of neuropeptide y (npy)/agouti-related protein (agrp) neurons, which express growth hormone secretagogue receptor type 1a (ghs-r1a), in the arcuate nucleus of the hypothalamus (arc) in male rats. |
2013-09-03 |
2023-08-12 |
rat |
| Janine J Geerling, Yanan Wang, Louis M Havekes, Johannes A Romijn, Patrick C N Rense. Acute central neuropeptide Y administration increases food intake but does not affect hepatic very low-density lipoprotein (VLDL) production in mice. PloS one. vol 8. issue 2. 2013-09-03. PMID:23460782. |
central neuropeptide y (npy) administration stimulates food intake in rodents. |
2013-09-03 |
2023-08-12 |
mouse |
| Yih-Shou Hsieh, Meng-Hsien Kuo, Pei-Ni Chen, Dong-Yih Ku. The identification of neuropeptide Y receptor subtype involved in phenylpropanolamine-induced increase in oxidative stress and appetite suppression. Neuromolecular medicine. vol 15. issue 1. 2013-08-29. PMID:23179670. |
changes in food intake and hypothalamic npy, y1r, y5r, and sod contents were assessed and compared. |
2013-08-29 |
2023-08-12 |
rat |
| Yih-Shou Hsieh, Meng-Hsien Kuo, Pei-Ni Chen, Dong-Yih Ku. The identification of neuropeptide Y receptor subtype involved in phenylpropanolamine-induced increase in oxidative stress and appetite suppression. Neuromolecular medicine. vol 15. issue 1. 2013-08-29. PMID:23179670. |
results showed that food intake and npy contents were decreased following ppa treatment, while y1r and sod contents were increased and y5r contents remained unchanged. |
2013-08-29 |
2023-08-12 |
rat |
| Yih-Shou Hsieh, Meng-Hsien Kuo, Pei-Ni Chen, Dong-Yih Ku. The identification of neuropeptide Y receptor subtype involved in phenylpropanolamine-induced increase in oxidative stress and appetite suppression. Neuromolecular medicine. vol 15. issue 1. 2013-08-29. PMID:23179670. |
moreover, although y1r or y5r knockdown by themselves could modify the food intake, y1r but not y5r knockdown could modify ppa-induced anorexia as well as npy and sod contents. |
2013-08-29 |
2023-08-12 |
rat |
| Ana Belén Gómez-SanMiguel, Ana Isabel Martín, Maria Paz Nieto-Bona, Carmen Fernández-Galaz, María López-Menduiña, María Ángeles Villanúa, Asunción López-Calderó. Systemic α-melanocyte-stimulating hormone administration decreases arthritis-induced anorexia and muscle wasting. American journal of physiology. Regulatory, integrative and comparative physiology. vol 304. issue 10. 2013-07-22. PMID:23515620. |
arthritis decreased food intake, but it increased hypothalamic expression of neuropeptide y (npy) and agouti-related peptides (agrp) as well as interleukin-1β (il-1β) and cyclooxygenase-2 (cox-2) mrna. |
2013-07-22 |
2023-08-12 |
rat |
| X L Ma, L W Zheng, L T Mao, L B Zhou, A L Wan. Neuropeptide Y in black seabream Acanthopagrus schlegelii: identification, distribution and mRNA expression responses to ghrelin. Journal of fish biology. vol 82. issue 4. 2013-06-24. PMID:23557320. |
treatment with acylated ghrelin significantly up-regulated npy mrna level in the hypothalamus, suggesting that npy may be involved in regulating food intake of a. schlegelii. |
2013-06-24 |
2023-08-12 |
Not clear |
| Arun K Tiwari, Eva J Brandl, Caroline Weber, Olga Likhodi, Clement C Zai, Margaret K Hahn, Jeffrey A Lieberman, Herbert Y Meltzer, James L Kennedy, Daniel J Mülle. Association of a functional polymorphism in neuropeptide Y with antipsychotic-induced weight gain in schizophrenia patients. Journal of clinical psychopharmacology. vol 33. issue 1. 2013-06-12. PMID:23277265. |
because npy is a potent orexigenic peptide stimulating food intake, and genetic variation of the gene has been shown to influence development of obesity, we investigated the impact of npy polymorphisms on antipsychotic-induced bwg.we analyzed 5 polymorphisms in the npy gene (rs10551063, rs16147, rs5573, rs5574, and rs16475) in schizophrenia subjects (n = 226), treated mostly with clozapine and olanzapine for up to 14 weeks. |
2013-06-12 |
2023-08-12 |
human |
| Rim Hassouna, Philippe Zizzari, Odile Viltart, Seung-Kwon Yang, Robert Gardette, Catherine Videau, Emilio Badoer, Jacques Epelbaum, Virginie Toll. A natural variant of obestatin, Q90L, inhibits ghrelin's action on food intake and GH secretion and targets NPY and GHRH neurons in mice. PloS one. vol 7. issue 12. 2013-06-11. PMID:23251435. |
a natural variant of obestatin, q90l, inhibits ghrelin's action on food intake and gh secretion and targets npy and ghrh neurons in mice. |
2013-06-11 |
2023-08-12 |
mouse |
| Rim Hassouna, Philippe Zizzari, Odile Viltart, Seung-Kwon Yang, Robert Gardette, Catherine Videau, Emilio Badoer, Jacques Epelbaum, Virginie Toll. A natural variant of obestatin, Q90L, inhibits ghrelin's action on food intake and GH secretion and targets NPY and GHRH neurons in mice. PloS one. vol 7. issue 12. 2013-06-11. PMID:23251435. |
in the present study, we tested the activity of native and q90l obestatin to modulate ghrelin-induced food intake, gh secretion, cfos activity in ghrh and neuropeptide y (npy) neurons and γ-aminobutyric-acid activity onto ghrh neurons. |
2013-06-11 |
2023-08-12 |
mouse |
| Li-Na Wang, Sheng-Li Li, Chuang-Hong Li, Chen-Xu Zhang, Hui Yuan, Xin-Ping L. [Diltiazem enhances food intake and gastrointestinal function in rats]. Sheng li xue bao : [Acta physiologica Sinica]. vol 64. issue 2. 2013-05-30. PMID:22513469. |
to detect the effects of diltiazem on food intake and body weight, the average daily food intake and body weight were recorded, and the serum metabolic hormones of plasma growth hormone (gh) and neuropeptide y (npy) were tested by radioimmunoassay. |
2013-05-30 |
2023-08-12 |
rat |
| Li-Na Wang, Sheng-Li Li, Chuang-Hong Li, Chen-Xu Zhang, Hui Yuan, Xin-Ping L. [Diltiazem enhances food intake and gastrointestinal function in rats]. Sheng li xue bao : [Acta physiologica Sinica]. vol 64. issue 2. 2013-05-30. PMID:22513469. |
the average daily food intake and body weight were significantly increased, and the serum concentrations of gh and npy were also remarkably increased in diltiazem-treated groups compared with those in control group. |
2013-05-30 |
2023-08-12 |
rat |
| J Wang, Z Yuan, J Dong, D Zhang, T Usami, T Murata, K Narita, T Higuch. Neuropeptide Y loses its orexigenic effect in rats with lesions of the hypothalamic paraventricular nucleus. Endocrine research. vol 38. issue 1. 2013-05-29. PMID:22594946. |
both neuropeptide y (npy) and ghrelin can enhance the feeding behavior. |
2013-05-29 |
2023-08-12 |
rat |
| Yuusuke Tamura, Kyouhei Hayashi, Naoki Omori, Yuji Nishiura, Kana Watanabe, Nobuyuki Tanaka, Masahiko Fujioka, Naoki Kouyama, Akira Yukimasa, Yukari Tanaka, Takeshi Chiba, Hideki Tanioka, Hirohide Nambu, Hideo Yukioka, Hiroki Sato, Takayuki Okun. Identification of a novel benzimidazole derivative as a highly potent NPY Y5 receptor antagonist with an anti-obesity profile. Bioorganic & medicinal chemistry letters. vol 23. issue 1. 2013-05-28. PMID:23206862. |
among them, derivative 4i inhibited food intake induced by the npy y5 selective agonist, and chronic oral administration of 4i in dio mice caused a dose-dependent reduction of body weight gain. |
2013-05-28 |
2023-08-12 |
mouse |
| Laura Butruille, Sylvain Mayeur, Thibaut Duparc, Claude Knauf, Emmanuelle Moitrot, Isabelle Fajardy, Philippe Valet, Laurent Storme, Philippe Deruelle, Jean Lesag. Prenatal fasudil exposure alleviates fetal growth but programs hyperphagia and overweight in the adult male rat. European journal of pharmacology. vol 689. issue 1-3. 2013-05-23. PMID:22683867. |
in 9 month-old rats, exposure to fasudil increased the daily food intake as well as hypothalamic mrna level of the orexigenic npy peptide without modulation of the anorexigenic pomc gene expression. |
2013-05-23 |
2023-08-12 |
rat |
| Lei Zhang, Miyuki Yagi, Herbert Herzo. The role of NPY and ghrelin in anorexia nervosa. Current pharmaceutical design. vol 18. issue 31. 2013-05-13. PMID:22632858. |
from the large number of players involved in this interplay, peptides from the neuropeptide y (npy) family are unique, with the predominantly neuronally expressed npy being one of the most strongly stimulating agents for food intake while its two other closely related family members peptide yy (pyy) and pancreatic polypeptide (pp) released from the gut induce satiety. |
2013-05-13 |
2023-08-12 |
Not clear |
| Lei Zhang, Miyuki Yagi, Herbert Herzo. The role of NPY and ghrelin in anorexia nervosa. Current pharmaceutical design. vol 18. issue 31. 2013-05-13. PMID:22632858. |
it is doing this by stimulating hypothalamic npy production and release, subsequently leading to increased appetite and feeding behaviour. |
2013-05-13 |
2023-08-12 |
Not clear |
| Peter Holzer, Florian Reichmann, Aitak Farz. Neuropeptide Y, peptide YY and pancreatic polypeptide in the gut-brain axis. Neuropeptides. vol 46. issue 6. 2013-05-06. PMID:22979996. |
in the brain, npy and its receptors (y1, y2, y4, y5) play important roles in regulating food intake, energy homeostasis, anxiety, mood and stress resilience. |
2013-05-06 |
2023-08-12 |
Not clear |
| Sheng Bi, Yonwook J Kim, Fenping Zhen. Dorsomedial hypothalamic NPY and energy balance control. Neuropeptides. vol 46. issue 6. 2013-05-06. PMID:23083763. |
in support of this view, adeno-associated virus (aav)-mediated overexpression of npy in the dmh causes increases in food intake and body weight and exacerbates high-fat diet-induced hyperphagia and obesity. |
2013-05-06 |
2023-08-12 |
rat |