| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rebecca Della Valle, Negin Mohammadmirzaei, Dayan Kno. Single prolonged stress alters neural activation in the periacqueductal gray and midline thalamic nuclei during emotional learning and memory. Learning & memory (Cold Spring Harbor, N.Y.). vol 26. issue 10. 2020-08-11. PMID:31527186. |
clinical and preclinical studies that have examined the neurobiology of persistent fear memory in posttraumatic stress disorder (ptsd) have focused on the medial prefrontal cortex, hippocampus, and amygdala. |
2020-08-11 |
2023-08-13 |
rat |
| Punita Kumari, Koustav Roy, Meetu Wadhwa, Garima Chauhan, Shahnawaz Alam, Krishna Kishore, Koushik Ray, Usha Panjwan. Fear memory is impaired in hypobaric hypoxia: Role of synaptic plasticity and neuro-modulators in limbic region. Life sciences. vol 254. 2020-07-21. PMID:32188570. |
therefore, the present study aims to investigate the effect of hh on biochemical and molecular mechanisms in amygdala involved in fear memory regulation along with the hippocampus and prefrontal cortex based fear memory. |
2020-07-21 |
2023-08-13 |
Not clear |
| Woong Bin Kim, Jun-Hyeong Ch. Encoding of contextual fear memory in hippocampal-amygdala circuit. Nature communications. vol 11. issue 1. 2020-07-13. PMID:32170133. |
here, we show that activity in the ventral ca1 (vca1) hippocampal projections to the basal amygdala (ba), paired with aversive stimuli, contributes to encoding conditioned fear memory. |
2020-07-13 |
2023-08-13 |
human |
| Henry L Hallock, Henry M Quillian, Yishan Mai, Kristen R Maynard, Julia L Hill, Keri Martinowic. Manipulation of a genetically and spatially defined sub-population of BDNF-expressing neurons potentiates learned fear and decreases hippocampal-prefrontal synchrony in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 13. 2020-07-08. PMID:31170726. |
brain-derived neurotrophic factor (bdnf) signaling regulates synaptic plasticity in the hippocampus (hc) and prefrontal cortex (pfc), and has been extensively linked with fear memory expression in rodents. |
2020-07-08 |
2023-08-13 |
mouse |
| Briana K Chen, Nathen J Murawski, Christine Cincotta, Olivia McKissick, Abby Finkelstein, Anahita B Hamidi, Emily Merfeld, Emily Doucette, Stephanie L Grella, Monika Shpokayte, Yosif Zaki, Amanda Fortin, Steve Ramire. Artificially Enhancing and Suppressing Hippocampus-Mediated Memories. Current biology : CB. vol 29. issue 11. 2020-06-22. PMID:31130452. |
fear memory suppression was associated with a reduction in hippocampal cells active during retrieval, while fear memory enhancement was associated with an increase in basolateral amygdala activity. |
2020-06-22 |
2023-08-13 |
Not clear |
| M Ghonghadze, K Pachkoria, M Okujava, N Antelava, N Gongadz. ENDOCANNABINOIDS RECEPTORS MEDIATED CENTRAL AND PERIPHERAL EFFECTS (REVIEW). Georgian medical news. issue 298. 2020-06-19. PMID:32141867. |
some data suggests that genetic or pharmacological inhibition of cox-2 activity may reduce disorders in hippocampal long-term synaptic plasticity and fear memory, as well as supports improving effects of tetrahydrocannabinoids (thc) on neurodegenerative processes such as alzheimer's disease, because thc facilitates to marked expression of an important endopeptidase neprilysin for degradation of ab proteins. |
2020-06-19 |
2023-08-13 |
Not clear |
| Jina Park, Seung Ju Park, Seyun Ki. Inositol polyphosphate multikinase deficiency leads to aberrant induction of synaptotagmin-2 in the forebrain. Molecular brain. vol 12. issue 1. 2020-05-26. PMID:31221192. |
conditional deletion of ipmk in excitatory neurons of the mouse postnatal forebrain results in enhanced extinction of fear memory accompanied by activation of p85 s6 kinase 1 signaling in the amygdala; it also facilitates hippocampal long-term potentiation. |
2020-05-26 |
2023-08-13 |
mouse |
| María Sol Kruse, Martín Javier Vadillo, Anabel María Mercedes Miguelez Fernández, Mariana Rey, Bonifacio Silvano Zanutto, Héctor Coirin. Sucrose exposure in juvenile rats produces long-term changes in fear memory and anxiety-like behavior. Psychoneuroendocrinology. vol 104. 2020-05-18. PMID:30928734. |
sucrose consumption during youth also affected fear behavior as animals exhibited impaired extinction of fear memory compared to control, indicating that prefrontal and hippocampal function is impaired. |
2020-05-18 |
2023-08-13 |
rat |
| Joseph B Rayman, Joud Hijazi, Xiang Li, Nancy Kedersha, Paul J Anderson, Eric R Kande. Genetic Perturbation of TIA1 Reveals a Physiological Role in Fear Memory. Cell reports. vol 26. issue 11. 2020-04-15. PMID:30865887. |
here, we show that tia1 bidirectionally modulates stress-dependent synaptic plasticity in the hippocampus, a brain region involved in fear memory and olfactory discrimination learning. |
2020-04-15 |
2023-08-13 |
Not clear |
| Marcelo Giachero, Eloisa Pavesi, Gastón Calfa, Simone C Motta, Newton S Canteras, Víctor A Molina, Antonio P Carobre. Inactivation of the dorsolateral periaqueductal gray matter impairs the promoting influence of stress on fear memory during retrieval. Brain structure & function. vol 224. issue 9. 2020-04-14. PMID:31511975. |
moreover, this treatment prevented the enhancement of the density of hippocampal "mature" spines associated with fear memory. |
2020-04-14 |
2023-08-13 |
rat |
| Liang Zhang, Xuanmao Chen, Carlos Sindreu, Song Lu, Daniel R Storm, Larry S Zweifel, Zhengui Xi. Dynamics of a hippocampal neuronal ensemble encoding trace fear memory revealed by in vivo Ca2+ imaging. PloS one. vol 14. issue 7. 2020-03-02. PMID:31269057. |
dynamics of a hippocampal neuronal ensemble encoding trace fear memory revealed by in vivo ca2+ imaging. |
2020-03-02 |
2023-08-13 |
mouse |
| Ankit Uniyal, Raghunath Singh, Ansab Akhtar, Yashika Bansal, Anurag Kuhad, Sangeeta Pilkhwal Sa. Co-treatment of piracetam with risperidone rescued extinction deficits in experimental paradigms of post-traumatic stress disorder by restoring the physiological alterations in cortex and hippocampus. Pharmacology, biochemistry, and behavior. vol 185. 2020-02-26. PMID:31445955. |
our preliminary study suggests that piracetam, risperidone and their combination restored the physiological cascades in cortex and hippocampus along with successful suppression of fear memory and a symptom cluster of ptsd-like phenotype in rats. |
2020-02-26 |
2023-08-13 |
rat |
| Sylvie L Lesuis, Paul J Lucassen, Harm J Kruger. Early life stress impairs fear memory and synaptic plasticity; a potential role for GluN2B. Neuropharmacology. vol 149. 2020-01-27. PMID:30641077. |
we demonstrate that els impaired fear memory in 6 month old mice and decreased hippocampal ltp as well as the paired-pulse ratio (ppr). |
2020-01-27 |
2023-08-13 |
mouse |
| Sylvie L Lesuis, Paul J Lucassen, Harm J Kruger. Early life stress impairs fear memory and synaptic plasticity; a potential role for GluN2B. Neuropharmacology. vol 149. 2020-01-27. PMID:30641077. |
these studies suggest that els reduces hippocampal synaptic plasticity and fear memory formation and hampers glun2b receptor function. |
2020-01-27 |
2023-08-13 |
mouse |
| Chad Smith, Tal Frolinger, Justin Brathwaite, Steven Sims, Giulio M Pasinett. Dietary polyphenols enhance optogenetic recall of fear memory in hippocampal dentate gyrus granule neuron subpopulations. Communications biology. vol 1. 2020-01-11. PMID:30271926. |
dietary polyphenols enhance optogenetic recall of fear memory in hippocampal dentate gyrus granule neuron subpopulations. |
2020-01-11 |
2023-08-13 |
Not clear |
| Mi Li, Kai Li, Hong Zhang, Yong Jian. Study on the mechanism of TMRK electroacupuncture in repairing synaptic plasticity in amygdala and hippocampus to relieve fear memory in PTSD rats. Technology and health care : official journal of the European Society for Engineering and Medicine. vol 27. issue S1. 2020-01-03. PMID:31045558. |
study on the mechanism of tmrk electroacupuncture in repairing synaptic plasticity in amygdala and hippocampus to relieve fear memory in ptsd rats. |
2020-01-03 |
2023-08-13 |
rat |
| Yusuke Kishimoto, Shingo Kasamatsu, Shuichi Yanai, Shogo Endo, Takaaki Akaike, Hideshi Ihar. 8-Nitro-cGMP attenuates context-dependent fear memory in mice. Biochemical and biophysical research communications. vol 511. issue 1. 2019-12-10. PMID:30773263. |
the results of an open-field test and fear-conditioning task revealed that icv infusion of 8-nitro-cgmp decreased the vertical activity and context-dependent fear memory of mice, which are both associated with the hippocampus. |
2019-12-10 |
2023-08-13 |
mouse |
| Lina Liu, Jing Yan, Fei Ge, Xiangtao Xu, Jun Lu, Huilian Shi, Shuihong Li, Yue Zhao, Changzheng Zhan. Saikosaponin‑D improves fear memory deficits in ovariectomized rats via the action of estrogen receptor‑α in the hippocampus. Molecular medicine reports. vol 20. issue 1. 2019-11-26. PMID:31115535. |
saikosaponin‑d improves fear memory deficits in ovariectomized rats via the action of estrogen receptor‑α in the hippocampus. |
2019-11-26 |
2023-08-13 |
rat |
| Lina Liu, Jing Yan, Fei Ge, Xiangtao Xu, Jun Lu, Huilian Shi, Shuihong Li, Yue Zhao, Changzheng Zhan. Saikosaponin‑D improves fear memory deficits in ovariectomized rats via the action of estrogen receptor‑α in the hippocampus. Molecular medicine reports. vol 20. issue 1. 2019-11-26. PMID:31115535. |
collectively, this study demonstrated that ssd‑mediated fear memory improvement in ovx rats may be attributed not to e2 levels or erβ activity, but to erα activation in the hippocampus. |
2019-11-26 |
2023-08-13 |
rat |
| Yu Ohmura, Takayuki Yoshida, Kohtarou Konno, Masabumi Minami, Masahiko Watanabe, Mitsuhiro Yoshiok. Serotonin 5-HT7 Receptor in the Ventral Hippocampus Modulates the Retrieval of Fear Memory and Stress-Induced Defecation. The international journal of neuropsychopharmacology. vol 19. issue 6. 2019-11-20. PMID:26647382. |
serotonin 5-ht7 receptor in the ventral hippocampus modulates the retrieval of fear memory and stress-induced defecation. |
2019-11-20 |
2023-08-13 |
Not clear |