| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J D Raybuck, K M Latta. Differential effects of dorsal hippocampal inactivation on expression of recent and remote drug and fear memory. Neuroscience letters. vol 569. 2014-12-09. PMID:24686177. |
differential effects of dorsal hippocampal inactivation on expression of recent and remote drug and fear memory. |
2014-12-09 |
2023-08-12 |
Not clear |
| Gisele Pereira Dias, Mário Cesar do Nascimento Bevilaqua, Anna Claudia Domingos Silveira da Luz, Renata Lopes Fleming, Lítia Alves de Carvalho, Graham Cocks, Danielle Beckman, Lucas Costa Hosken, William de Sant'Anna Machado, Ana Carolina Corrêa-e-Castro, Felippe Mousovich-Neto, Vítor de Castro Gomes, Gilmara de Nazareth Tavares Bastos, Regina Célia Cussa Kubrusly, Vânia Maria Corrêa da Costa, Deepak Srivastava, Jesus Landeira-Fernandez, Antonio Egidio Nardi, Sandrine Thuret, Patricia Franca Gardin. Hippocampal biomarkers of fear memory in an animal model of generalized anxiety disorder. Behavioural brain research. vol 263. 2014-12-03. PMID:24462725. |
hippocampal biomarkers of fear memory in an animal model of generalized anxiety disorder. |
2014-12-03 |
2023-08-12 |
rat |
| Qin Zhang, Xiaohong Xu, Tao Li, Yang Lu, Qin Ruan, Yingjun Lu, Qinwen Wang, Fangni Dong, Yanling Yang, Guangxia Zhan. Exposure to bisphenol-A affects fear memory and histone acetylation of the hippocampus in adult mice. Hormones and behavior. vol 65. issue 2. 2014-10-20. PMID:24333847. |
exposure to bisphenol-a affects fear memory and histone acetylation of the hippocampus in adult mice. |
2014-10-20 |
2023-08-12 |
mouse |
| Qin Zhang, Xiaohong Xu, Tao Li, Yang Lu, Qin Ruan, Yingjun Lu, Qinwen Wang, Fangni Dong, Yanling Yang, Guangxia Zhan. Exposure to bisphenol-A affects fear memory and histone acetylation of the hippocampus in adult mice. Hormones and behavior. vol 65. issue 2. 2014-10-20. PMID:24333847. |
these results suggest that long term exposure to bpa enhanced fear memory by the concomitant increased level of nmda receptor and/or the enhanced histone acetylation in the hippocampus, which may be associated with activation of erk1/2 signaling pathway. |
2014-10-20 |
2023-08-12 |
mouse |
| Stephen Mare. Fear of the unexpected: hippocampus mediates novelty-induced return of extinguished fear in rats. Neurobiology of learning and memory. vol 108. 2014-10-14. PMID:23791555. |
several lines of evidence indicate an important role for the hippocampus in the recovery of fear memory after extinction. |
2014-10-14 |
2023-08-12 |
rat |
| Hongmiao Zhang, Guifen Chen, Hui Kuang, Joe Z Tsie. Mapping and deciphering neural codes of NMDA receptor-dependent fear memory engrams in the hippocampus. PloS one. vol 8. issue 11. 2014-10-01. PMID:24302990. |
mapping and deciphering neural codes of nmda receptor-dependent fear memory engrams in the hippocampus. |
2014-10-01 |
2023-08-12 |
mouse |
| Hongmiao Zhang, Guifen Chen, Hui Kuang, Joe Z Tsie. Mapping and deciphering neural codes of NMDA receptor-dependent fear memory engrams in the hippocampus. PloS one. vol 8. issue 11. 2014-10-01. PMID:24302990. |
therefore, our study has decoded real-time memory contents, timing relationship between cs and us, and temporal organizing patterns of fear memory engrams and demonstrated how hippocampal memory codes are regulated by nmda receptor synaptic plasticity. |
2014-10-01 |
2023-08-12 |
mouse |
| Jorge R Bergado-Acosta, Iris Müller, Gal Richter-Levin, Oliver Stor. The GABA-synthetic enzyme GAD65 controls circadian activation of conditioned fear pathways. Behavioural brain research. vol 260. 2014-09-02. PMID:24300892. |
hyperactivity and reduced freezing during fear memory retrieval were accompanied by an increased induction of the immediate early gene cfos suggesting hyperactivation of the hippocampus, amygdala, and medial hypothalamus. |
2014-09-02 |
2023-08-12 |
mouse |
| Moriel Zelikowsky, Sarah Hersman, Monica K Chawla, Carol A Barnes, Michael S Fanselo. Neuronal ensembles in amygdala, hippocampus, and prefrontal cortex track differential components of contextual fear. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 25. 2014-08-12. PMID:24948801. |
collectively, these data provide crucial insight into the region-specific behavior of neuronal ensembles during contextual fear conditioning and demonstrate a dissociable role for the hippocampus and amygdala in processing the contextual and emotional properties of a fear memory. |
2014-08-12 |
2023-08-13 |
rat |
| Inmaculada Pereda-Pérez, Natalija Popović, Beatriz Baño Otalora, Miroljub Popović, Juan Antonio Madrid, Maria Angeles Rol, César Vener. Long-term social isolation in the adulthood results in CA1 shrinkage and cognitive impairment. Neurobiology of learning and memory. vol 106. 2014-08-11. PMID:23867635. |
after 6½ months of social isolation, adult female degus showed a normal auditory-cued fear memory, but a deficit in contextual fear memory, a hippocampal dependent task. |
2014-08-11 |
2023-08-12 |
Not clear |
| Nicola J Broadbent, Robert E Clar. Remote context fear conditioning remains hippocampus-dependent irrespective of training protocol, training-surgery interval, lesion size, and lesion method. Neurobiology of learning and memory. vol 106. 2014-08-11. PMID:23994542. |
accordingly, we evaluated classically conditioned fear memory in large groups of rats with hippocampal damage by manipulating several procedural variables including the training protocol, the training-surgery interval, the extent of hippocampal damage, and the method of damaging the hippocampus. |
2014-08-11 |
2023-08-12 |
rat |
| Xu Liu, Steve Ramirez, Susumu Tonegaw. Inception of a false memory by optogenetic manipulation of a hippocampal memory engram. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 369. issue 1633. 2014-08-11. PMID:24298144. |
here, we first identified a population of cells in the dentate gyrus (dg) of the hippocampus that bear the engrams for a specific context; these cells were naturally activated during the encoding phase of fear conditioning and their artificial reactivation using optogenetics in an unrelated context was sufficient for inducing the fear memory specific to the conditioned context. |
2014-08-11 |
2023-08-12 |
Not clear |
| Matthew R Durk, Kyung Han, Edwin C Y Chow, Rosemary Ahrens, Jeffrey T Henderson, Paul E Fraser, K Sandy Pan. 1α,25-Dihydroxyvitamin D3 reduces cerebral amyloid-β accumulation and improves cognition in mouse models of Alzheimer's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 21. 2014-07-11. PMID:24849345. |
long-term treatment of tgcrnd8 mice with 1,25(oh)2d3 during the period of plaque formation reduced soluble and insoluble plaque-associated aβ, particularly in the hippocampus in which the vdr is abundant and p-gp induction is greatest after 1,25(oh)2d3 treatment, and this led to improved conditioned fear memory. |
2014-07-11 |
2023-08-13 |
mouse |
| Tilman Breiderhoff, Gitte B Christiansen, Lone T Pallesen, Christian Vaegter, Anders Nykjaer, Mai Marie Holm, Simon Glerup, Thomas E Willno. Sortilin-related receptor SORCS3 is a postsynaptic modulator of synaptic depression and fear extinction. PloS one. vol 8. issue 9. 2014-06-15. PMID:24069373. |
consistent with a loss of synaptic retraction, sorcs3-deficient mice suffer from deficits in behavioral activities associated with hippocampal ltd, particularly from an accelerated extinction of fear memory. |
2014-06-15 |
2023-08-12 |
mouse |
| K McEown, D Trei. Α2 GABAA receptor sub-units in the ventral hippocampus and α5 GABAA receptor sub-units in the dorsal hippocampus mediate anxiety and fear memory. Neuroscience. vol 252. 2014-06-11. PMID:23962649. |
Α2 gabaa receptor sub-units in the ventral hippocampus and α5 gabaa receptor sub-units in the dorsal hippocampus mediate anxiety and fear memory. |
2014-06-11 |
2023-08-12 |
rat |
| K McEown, D Trei. Α2 GABAA receptor sub-units in the ventral hippocampus and α5 GABAA receptor sub-units in the dorsal hippocampus mediate anxiety and fear memory. Neuroscience. vol 252. 2014-06-11. PMID:23962649. |
on the other hand, inactivating the dorsal hippocampus disrupts fear memory, while inactivating the ventral hippocampus does not. |
2014-06-11 |
2023-08-12 |
rat |
| K McEown, D Trei. Α2 GABAA receptor sub-units in the ventral hippocampus and α5 GABAA receptor sub-units in the dorsal hippocampus mediate anxiety and fear memory. Neuroscience. vol 252. 2014-06-11. PMID:23962649. |
this double dissociation suggests that α2 gabaa receptor sub-units in the ventral hippocampus mediate unconditioned fear or anxiety, while α5 gabaa receptor sub-units in the dorsal hippocampus mediate conditioned fear memory. |
2014-06-11 |
2023-08-12 |
rat |
| Georgette M Gafford, Ryan G Parsons, Fred J Helmstette. Memory accuracy predicts hippocampal mTOR pathway activation following retrieval of contextual fear memory. Hippocampus. vol 23. issue 9. 2014-04-09. PMID:23640842. |
we tested whether p70s6 kinase (p70s6k), a key component of the mtor signaling pathway, is activated following retrieval of context fear memory in the dorsal hippocampus (dh) and anterior cingulate cortex (acc) at 1, 10, or 36 days after context fear conditioning. |
2014-04-09 |
2023-08-12 |
Not clear |
| C P Fitzsimons, L W A van Hooijdonk, M Schouten, I Zalachoras, V Brinks, T Zheng, T G Schouten, D J Saaltink, T Dijkmans, D A Steindler, J Verhaagen, F J Verbeek, P J Lucassen, E R de Kloet, O C Meijer, H Karst, M Joels, M S Oitzl, E Vreugdenhi. Knockdown of the glucocorticoid receptor alters functional integration of newborn neurons in the adult hippocampus and impairs fear-motivated behavior. Molecular psychiatry. vol 18. issue 9. 2014-03-25. PMID:22925833. |
together, our data demonstrate a key role for the gr in newborn hippocampal cells in mediating their synaptic connectivity and structural as well as functional integration into mature hippocampal circuits involved in fear memory consolidation. |
2014-03-25 |
2023-08-12 |
Not clear |
| Ashley C Chen, Amit Etki. Hippocampal network connectivity and activation differentiates post-traumatic stress disorder from generalized anxiety disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 10. 2014-03-24. PMID:23673864. |
as the hippocampus is implicated in both general anxiety and fear memory, it may be an important brain locus for mapping the similarities and differences among anxiety disorders. |
2014-03-24 |
2023-08-12 |
human |