| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Szentiványi, A P Zou, C Y Maeda, D L Mattson, A W Cowle. Increase in renal medullary nitric oxide synthase activity protects from norepinephrine-induced hypertension. Hypertension (Dallas, Tex. : 1979). vol 35. issue 1 Pt 2. 2000-02-07. PMID:10642335. |
studies were performed in conscious sprague-dawley rats to determine the role of the alpha(2)-adrenergic receptor-mediated increase in the renal medullary nitric oxide synthase (nos) activity as a counterregulatory mechanism of blood pressure control in response to increased renal adrenergic stimulation. |
2000-02-07 |
2023-08-12 |
rat |
| G A Hea. Central imidazoline- and alpha 2-receptors involved in the cardiovascular actions of centrally acting antihypertensive agents. Annals of the New York Academy of Sciences. vol 881. 1999-08-10. PMID:10415926. |
we used conscious rabbits and imidazoline and specific alpha 2-adrenoceptor antagonists to show that second-generation agents rilmenidine and moxonidine act preferentially through imidazoline receptors but that alpha 2-adrenoceptors are important for the hypotension produced by clonidine and alpha-methyldopa. |
1999-08-10 |
2023-08-12 |
Not clear |
| Q M Zhu, J D Lesnick, J R Jasper, S J MacLennan, M P Dillon, R M Eglen, D R Blu. alpha 2A-adrenoceptors, not I1-imidazoline receptors, mediate the hypotensive effects of rilmenidine and moxonidine in conscious mice. In vivo and in vitro studies. Annals of the New York Academy of Sciences. vol 881. 1999-08-10. PMID:10415927. |
alpha 2a-adrenoceptors, not i1-imidazoline receptors, mediate the hypotensive effects of rilmenidine and moxonidine in conscious mice. |
1999-08-10 |
2023-08-12 |
mouse |
| B S Huang, F H Leene. Brain renin-angiotensin system and ouabain-induced sympathetic hyperactivity and hypertension in Wistar rats. Hypertension (Dallas, Tex. : 1979). vol 34. issue 1. 1999-08-02. PMID:10406832. |
on day 15, mean arterial pressure, heart rate, central venous pressure, and renal sympathetic nerve activity were recorded in conscious rats at rest and in response to air-jet stress, intracerebroventricular injection of the alpha(2)-agonist guanabenz (25 and 75 micrograms) or angiotensin ii (30 ng), acute volume expansion, and ramp changes of blood pressure by +/-50 mm hg with phenylephrine and nitroprusside. |
1999-08-02 |
2023-08-12 |
rat |
| D Fanini, M Poglio, M C Marci, G Iovinelli, F Antenucc. [Oral premedication with clonidine as an alternative in dental practice. The effects on the pain threshold, blood pressure and salivary flow]. Minerva stomatologica. vol 47. issue 9. 1999-01-04. PMID:9835755. |
clonidine, an alpha 2-adrenoceptor agonist, has been recently shown to be effective in conscious sedation because of its analgesic and sedative properties, having also proven to be active in reducing neuroendocrine responses to stressful stimuli perioperatively. |
1999-01-04 |
2023-08-12 |
Not clear |
| P S Pagel, L T Proctor, A Devcic, D A Hettrick, J R Kersten, J P Tessmer, N E Farber, W T Schmeling, D C Warltie. A novel alpha 2-adrenoceptor antagonist attenuates the early, but preserves the late cardiovascular effects of intravenous dexmedetomidine in conscious dogs. Journal of cardiothoracic and vascular anesthesia. vol 12. issue 4. 1998-10-27. PMID:9713732. |
a novel alpha 2-adrenoceptor antagonist attenuates the early, but preserves the late cardiovascular effects of intravenous dexmedetomidine in conscious dogs. |
1998-10-27 |
2023-08-12 |
Not clear |
| P S Pagel, L T Proctor, A Devcic, D A Hettrick, J R Kersten, J P Tessmer, N E Farber, W T Schmeling, D C Warltie. A novel alpha 2-adrenoceptor antagonist attenuates the early, but preserves the late cardiovascular effects of intravenous dexmedetomidine in conscious dogs. Journal of cardiothoracic and vascular anesthesia. vol 12. issue 4. 1998-10-27. PMID:9713732. |
to test the hypothesis that l-659,066, a peripherally acting alpha 2-adrenoceptor agonist, will abolish the early pressor response but preserve the late depressor action of intravenous dexmedetomidine in conscious, unsedated dogs. |
1998-10-27 |
2023-08-12 |
Not clear |
| B S Huang, S J Veerasingham, F H Leene. Brain "ouabain," ANG II, and sympathoexcitation by chronic central sodium loading in rats. The American journal of physiology. vol 274. issue 4. 1998-06-02. PMID:9575931. |
in conscious rats, sodium-rich acsf increased baseline mean arterial pressure (map), enhanced map, heart rate (hr), and renal sympathetic nerve activity (rsna) responses to intracerebroventricular alpha 2-adrenoceptor agonist guanabenz and air stress, and desensitized arterial and cardiopulmonary baroreflex control of hr and rsna. |
1998-06-02 |
2023-08-12 |
rat |
| R Yamaji, Y Ohnishi, M Sakamoto, M Takenoshita, M Ohta, S Tsuyama, F Watanabe, H Inui, K Miyatake, Y Nakan. Alpha 2-adrenoceptor-mediated antisecretory effect of hypoxia in conscious rats. Bioscience, biotechnology, and biochemistry. vol 62. issue 3. 1998-05-27. PMID:9571785. |
alpha 2-adrenoceptor-mediated antisecretory effect of hypoxia in conscious rats. |
1998-05-27 |
2023-08-12 |
rat |
| M J García-Barrado, M Reverte, J Palomero, J Moratino. Comparative effects of calcium channel blockers and indomethacin on insulin secretion and blood pressure increase derived from alpha 1-adrenoceptor stimulation in the rabbit. Journal of autonomic pharmacology. vol 17. issue 5. 1998-02-03. PMID:9427108. |
in conscious, fasted rabbits the intravenous infusion of the alpha 1-adrenoceptor agonist, amidephrine (3 and 10 micrograms kg-1 min-1) induced a dose related increase in insulin plasma levels. |
1998-02-03 |
2023-08-12 |
rabbit |
| C S Celly, W N McDonell, W D Black, S S Youn. Cardiopulmonary effects of clonidine, diazepam and the peripheral alpha 2 adrenoceptor agonist ST-91 in conscious sheep. Journal of veterinary pharmacology and therapeutics. vol 20. issue 6. 1998-01-30. PMID:9430771. |
cardiopulmonary effects of clonidine, diazepam and the peripheral alpha 2 adrenoceptor agonist st-91 in conscious sheep. |
1998-01-30 |
2023-08-12 |
Not clear |
| B Szabo, R Urba. Role of I1 imidazoline receptors in the sympathoinhibition produced by intracisternally administered rilmenidine and moxonidine. Arzneimittel-Forschung. vol 47. issue 9. 1997-12-08. PMID:9342413. |
the role of alpha 2-adrenoceptors and i1 imidazoline receptors in the cardiovascular effects of rilmenidine (cas 54187-04-1), moxonidine (cas 75438-57-2) and guanabenz (cas 23256-50-0) was studied in conscious rabbits. |
1997-12-08 |
2023-08-12 |
Not clear |
| H M Siragy, R M Care. The subtype 2 angiotensin receptor regulates renal prostaglandin F2 alpha formation in conscious rats. The American journal of physiology. vol 273. issue 3 Pt 2. 1997-10-23. PMID:9321892. |
the subtype 2 angiotensin receptor regulates renal prostaglandin f2 alpha formation in conscious rats. |
1997-10-23 |
2023-08-12 |
rat |
| H M Siragy, R M Care. The subtype 2 angiotensin receptor regulates renal prostaglandin F2 alpha formation in conscious rats. The American journal of physiology. vol 273. issue 3 Pt 2. 1997-10-23. PMID:9321892. |
using a microdialysis technique, we monitored changes in renal interstitial fluid pge2 and pgf2 alpha in response to 5 days of sodium depletion alone or a combination of sodium depletion and intravenous infusion of the at1 receptor blocker losartan or the at2 receptor blocker pd-123319 in conscious rats. |
1997-10-23 |
2023-08-12 |
rat |
| H Gao, W J Welch, G F DiBona, C S Wilco. Sympathetic nervous system and hypertension during prolonged TxA2/PGH2 receptor activation in rats. The American journal of physiology. vol 273. issue 2 Pt 2. 1997-09-25. PMID:9277490. |
in conclusion, hypertension during prolonged infusions of u-46619 into conscious, salt-loaded rats is accompanied by an increase in total and renal vascular resistance and is dependent on peripheral but not central txa2/pgh2 receptors and on the autonomic and alpha 1-adrenergic peripheral sympathetic nervous systems. |
1997-09-25 |
2023-08-12 |
rat |
| O Ishizuka, R K Pandita, A Mattiasson, W D Steers, K E Andersso. Stimulation of bladder activity by volume, L-dopa and capsaicin in normal conscious rats--effects of spinal alpha 1-adrenoceptor blockade. Naunyn-Schmiedeberg's archives of pharmacology. vol 355. issue 6. 1997-08-27. PMID:9205965. |
stimulation of bladder activity by volume, l-dopa and capsaicin in normal conscious rats--effects of spinal alpha 1-adrenoceptor blockade. |
1997-08-27 |
2023-08-12 |
rat |
| O Ishizuka, A Mattiasson, W D Steers, K E Andersso. Effects of spinal alpha 1-adrenoceptor antagonism on bladder activity induced by apomorphine in conscious rats with and without bladder outlet obstruction. Neurourology and urodynamics. vol 16. issue 3. 1997-08-15. PMID:9136141. |
effects of spinal alpha 1-adrenoceptor antagonism on bladder activity induced by apomorphine in conscious rats with and without bladder outlet obstruction. |
1997-08-15 |
2023-08-12 |
rat |
| K Jo. [Predictive indicators for progression to severe complications(hemolytic-uremic syndrome and encephalopathy) and their prevention in enterohemorrhagic Escherichia coli infection]. Nihon rinsho. Japanese journal of clinical medicine. vol 55. issue 3. 1997-06-17. PMID:9086784. |
predictors for complications include severe abdominal pain and bloody diarrhea development of high fever, change of consciousness, urinal protein and/or occult blood, abrupt increase of white blood cell count, urinal nag, alpha 1 microglobulin, beta 2 microglobulin, low osmolar urine, high thrombomodulin level, marked thickening of intestinal wall, increased brightness of kidney in ultrasound sonography. |
1997-06-17 |
2023-08-12 |
Not clear |
| W A Saad, G P Camargo, L A Camarg. On a dual role for clonidine stimulation of the ventromedial nucleus of the hypothalamus in sodium and potassium renal excretions of rats. Pharmacology. vol 53. issue 5. 1997-06-12. PMID:8990486. |
the effects of clonidine on sodium and potassium excretions were examined after previous administration of prazosin (an alpha 1-adrenergic receptor antagonist) and yohimbine (an alpha 2-adrenergic receptor antagonist) into the ventromedial nucleus of the hypothalamus of conscious rats. |
1997-06-12 |
2023-08-12 |
rat |
| K Ohashi, T Saigus. Sympathetic nervous responses during cytokine-induced fever in conscious rabbits. Pflugers Archiv : European journal of physiology. vol 433. issue 6. 1997-06-10. PMID:9049158. |
sympathetic responses during fever induced by two representative endogenous pyrogens, interleukin-1 beta (il-1 beta) and tumor necrosis factor alpha (tnf alpha), and their effective inducer, lipopolysaccharide (lps), were investigated in conscious rabbits. |
1997-06-10 |
2023-08-12 |
Not clear |