| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kiheon Baek, Alexander D Noblett, Pengyu Ren, Laura J Sugg. Design and Characterization of Nucleopeptides for Hydrogel Self-Assembly. ACS applied bio materials. vol 2. issue 7. 2022-01-15. PMID:35030815. |
self-assembling peptides can be used in a bottom-up approach to build hydrogels that are similar to the extracellular matrix at both structural and functional levels. |
2022-01-15 |
2023-08-13 |
Not clear |
| Philip Boucher, Clair Goug. Mapping the ethical landscape of carbon capture and storage. Poiesis & praxis : international journal of ethics of science and technology assessment. vol 9. issue 3-4. 2021-10-21. PMID:23226998. |
this imitates a bottom-up analytic structure in the absence of the direct participation of actors, culminating in the construction of a map of the ethical landscape; a high-resolution ethical matrix of coded interpretations of various actors' ethical framings of the technology. |
2021-10-21 |
2023-08-12 |
Not clear |
| Hai-Jun Su, Hongliang Shi, Jingjun Y. A Symbolic Formulation for Analytical Compliance Analysis and Synthesis of Flexure Mechanisms. Journal of mechanical design (New York, N.Y. : 1990). vol 134. issue 5. 2021-10-21. PMID:23904747. |
at last, we use a bottom-up approach to obtain the compliance/stiffness matrix for the overall mechanism. |
2021-10-21 |
2023-08-12 |
Not clear |
| Francesco Branda, Aurelio Bifulco, Dieter Jehnichen, Dambarudhar Parida, Robin Pauer, Jessica Passaro, Sabyasachi Gaan, Doris Pospiech, Massimo Durant. Structure and Bottom-up Formation Mechanism of Multisheet Silica-Based Nanoparticles Formed in an Epoxy Matrix through an Langmuir : the ACS journal of surfaces and colloids. vol 37. issue 29. 2021-09-01. PMID:34275300. |
structure and bottom-up formation mechanism of multisheet silica-based nanoparticles formed in an epoxy matrix through an organic/inorganic hybrid composite materials with the dispersed phases in sizes down to a few tens of nanometers raised very great interest. |
2021-09-01 |
2023-08-13 |
Not clear |
| Costantino Casale, Giorgia Imparato, Claudia Mazio, Paolo A Netti, Francesco Urciuol. Geometrical confinement controls cell, ECM and vascular network alignment during the morphogenesis of 3D bioengineered human connective tissues. Acta biomaterialia. vol 131. 2021-08-31. PMID:34144214. |
here, we show a new method to align de novo synthesized extracellular matrix components in bioengineered connective tissues obtained by means of a bottom-up tissue engineering approach. |
2021-08-31 |
2023-08-13 |
human |
| Luís P Ferreira, Vítor M Gaspar, Luís Mendes, Iola F Duarte, João F Man. Organotypic 3D decellularized matrix tumor spheroids for high-throughput drug screening. Biomaterials. vol 275. 2021-08-26. PMID:34186236. |
to address this, herein we employed ultra-low adhesion surfaces for bioengineering organotypic 3d metastatic breast cancer-fibroblast models enriched with decm microfibrillar fragments, as a bottom-up strategy to include major matrix components and their associated biomolecular cues during the early stages of 3d microtissue spheroids assembly, simulating pre-existing ecm presence in the in vivo setting. |
2021-08-26 |
2023-08-13 |
Not clear |
| Jingwen Zhang, Song Li, Zhengyi Zhu, Zhenwang Wu, Jiuxing Zhan. Enhancing the thermoelectric properties of SnTe Dalton transactions (Cambridge, England : 2003). vol 50. issue 30. 2021-08-04. PMID:34259288. |
in this work, an amorphous carbon core-shell-coated pbte nanostructure prepared by a "bottom-up" method is first incorporated into the sn1-ysbyte matrix to enhance the thermoelectric performance of snte. |
2021-08-04 |
2023-08-13 |
Not clear |
| Chih-Yu Wu, Ting-Ying Wu, Zhen-Yu Guan, Peng-Yuan Wang, Yen-Ching Yang, Chao-Wei Huang, Tzu-Hung Lin, Hsien-Yeh Che. Vapor-phased fabrication and modulation of cell-laden scaffolding materials. Nature communications. vol 12. issue 1. 2021-06-15. PMID:34099701. |
bottom-up approaches using building blocks of modules to fabricate scaffolds for tissue engineering applications have enabled the fabrication of structurally complex and multifunctional materials allowing for physical and chemical flexibility to better mimic the native extracellular matrix. |
2021-06-15 |
2023-08-13 |
Not clear |
| Assal Daneshgar, Oliver Klein, Grit Nebrich, Marie Weinhart, Peter Tang, Alexander Arnold, Imran Ullah, Julian Pohl, Simon Moosburner, Nathanael Raschzok, Benjamin Strücker, Marcus Bahra, Johann Pratschke, Igor M Sauer, Karl H Hillebrand. The human liver matrisome - Proteomic analysis of native and fibrotic human liver extracellular matrices for organ engineering approaches. Biomaterials. vol 257. 2021-05-14. PMID:32739662. |
here we present a thorough analysis of the native human liver proteomic landscape using decellularization and defatting protocols to create extracellular matrix scaffolds of natural origin that can further be used in both bottom-up and top-down approaches in tissue engineering based organ replacements. |
2021-05-14 |
2023-08-13 |
human |
| Matthew R Arkenberg, Han D Nguyen, Chien-Chi Li. Recent advances in bio-orthogonal and dynamic crosslinking of biomimetic hydrogels. Journal of materials chemistry. B. vol 8. issue 35. 2021-03-29. PMID:32692329. |
the high degree of tunability in crosslinking reactions of orthogonal 'click' chemistry has enabled a bottom-up approach to install specific biomimicry in an artificial extracellular matrix. |
2021-03-29 |
2023-08-13 |
Not clear |
| Kiheon Baek, Alexander David Noblett, Pengyu Ren, Laura J Sugg. Self-assembled nucleo-tripeptide hydrogels provide local and sustained doxorubicin release. Biomaterials science. vol 8. issue 11. 2021-01-18. PMID:32352097. |
these hydrogels have specific benefits for biomedical applications due to their dna-like interactions in addition to the well-known advantages of peptide biomaterials: biocompatibility, extracellular matrix (ecm)-like structure, and bottom-up design. |
2021-01-18 |
2023-08-13 |
mouse |
| Stefano Levi Mortera, Federica Del Chierico, Pamela Vernocchi, Maria M Rosado, Agnese Cavola, Marco Chierici, Luisa Pieroni, Andrea Urbani, Rita Carsetti, Isabella Lante, Bruno Dallapiccola, Lorenza Putignan. Monitoring Perinatal Gut Microbiota in Mouse Models by Mass Spectrometry Approaches: Parental Genetic Background and Breastfeeding Effects. Frontiers in microbiology. vol 7. 2020-09-30. PMID:27725814. |
to investigate these topics, we used either a culturomic approach that employed matrix assisted laser desorption ionization time-of-flight mass spectrometry (ms), or bottom-up liquid chromatography, with subsequent msms shotgun metaproteomic analysis that compared and assembled results of the two techniques. |
2020-09-30 |
2023-08-13 |
mouse |
| Solveig M Bartelt, Elizaveta Chervyachkova, Julia Ricken, Seraphine V Wegne. Mimicking Adhesion in Minimal Synthetic Cells. Advanced biosystems. vol 3. issue 6. 2020-09-23. PMID:32648713. |
cell adhesions to the extracellular matrix and to neighboring cells are fundamental to cell behavior and have also been implemented into minimal synthetic cells, which are assembled from molecular building blocks from the bottom-up. |
2020-09-23 |
2023-08-13 |
Not clear |
| Yingjie Li, Xiaotong Lin, Shili Qin, Lidi Gao, Yimin Tang, Shuren Liu, Yuanyuan Wan. β-Cyclodextrin-modified covalent organic framework as chiral stationary phase for the separation of amino acids and β-blockers by capillary electrochromatography. Chirality. vol 32. issue 7. 2020-06-24. PMID:32329149. |
here, a novel isocyanate-β-cyclodextrin-modified cof (mdi-β-cd-modified cof) was synthesized using isocyanate-β-cyclodextrin as the chiral selector and imine-based tppa-1 cof as the matrix by a bottom-up strategy. |
2020-06-24 |
2023-08-13 |
Not clear |
| Andrew T Rowley, Raji R Nagalla, Szu-Wen Wang, Wendy F Li. Extracellular Matrix-Based Strategies for Immunomodulatory Biomaterials Engineering. Advanced healthcare materials. vol 8. issue 8. 2020-06-22. PMID:30714328. |
by contrast, a bottom-up approach leverages immunomodulatory domains, such as arg-gly-asp (rgd), matrix metalloproteinase (mmp)-sensitive peptides, or leukocyte-associated immunoglobulin-like receptor-1(lair-1) ligands, by incorporating them into synthetic materials. |
2020-06-22 |
2023-08-13 |
Not clear |
| Xi Zhan. Seven perspectives on GPCR H/D-exchange proteomics methods. F1000Research. vol 6. 2019-11-20. PMID:28529698. |
this article proposes to view bottom-up hdx as two steps to guide choices of detergent buffers and chromatography settings: (i) protein hdx labeling in native buffers, and (ii) peptide-centric analysis of hdx labels, which applies (a) bottom-up ms/ms to construct peptide matrix and (b) hdx ms to locate and quantify h/d labels. |
2019-11-20 |
2023-08-13 |
human |
| Simon H Tran, Clive G Wilson, F Philipp Sei. A Review of the Emerging Role of Silk for the Treatment of the Eye. Pharmaceutical research. vol 35. issue 12. 2019-07-09. PMID:30397820. |
the progression of top-down and bottom-up engineering approaches using silk as the basis of a drug delivery or cell-loaded matrix helped to re-ignite interest in this ancient material. |
2019-07-09 |
2023-08-13 |
Not clear |
| Xiaojing Shen, Liangliang Su. Systematic Evaluation of Immobilized Trypsin-Based Fast Protein Digestion for Deep and High-Throughput Bottom-Up Proteomics. Proteomics. vol 18. issue 9. 2019-07-04. PMID:29577644. |
how does the solid matrix of im influence its preference for protein cleavage and how well can im perform for deep bottom-up proteomics compared to ft? |
2019-07-04 |
2023-08-13 |
mouse |
| Yvonne Pasing, Armin Schniers, Terkel Hanse. Straightforward Protocol for Gel-Free Proteomic Analysis of Adipose Tissue. Methods in molecular biology (Clifton, N.J.). vol 1788. 2019-02-28. PMID:28980277. |
adipose tissue as a matrix in bottom-up proteomics is challenging due to the extremely high lipid content.the lysis buffer utilized contains the detergent sodium deoxycholate, which does not impair the activity of trypsin and therefore enables direct digestion without detergent removal steps. |
2019-02-28 |
2023-08-13 |
Not clear |
| Øystein Skjærvø, Eirik J Solbakk, Trine Grønhaug Halvorsen, Léon Reubsae. Paper-based immunocapture for targeted protein analysis. Talanta. vol 195. 2019-02-20. PMID:30625614. |
a novel sampling concept for mass spectrometric bottom-up targeted protein analysis is here demonstrated with polymeric sampling spots integrated with instant immunocapture for analysis of dried matrix spots. |
2019-02-20 |
2023-08-13 |
human |