All Relations between apoptosis and spinal cord

Publication Sentence Publish Date Extraction Date Species
Qifei Xu, Fanguo Kong, Guanghui Zhao, Junwei Jin, Shengkai Feng, Ming L. USP7 alleviates neuronal inflammation and apoptosis in spinal cord injury via deubiquitinating NRF1/KLF7 axis. Neurological research. 2024-07-15. PMID:39007840. usp7 alleviates neuronal inflammation and apoptosis in spinal cord injury via deubiquitinating nrf1/klf7 axis. 2024-07-15 2024-07-18 Not clear
Meng Li, Jinfeng Mo, Deguang Wu, Haibo He, Panyong H. Treadmill training improves neural function recovery in rats with spinal cord injury via JAK2/STAT3 signaling pathway and attenuating apoptosis. Neuroreport. 2024-07-08. PMID:38973489. treadmill training improves neural function recovery in rats with spinal cord injury via jak2/stat3 signaling pathway and attenuating apoptosis. 2024-07-08 2024-07-11 rat
Meng Li, Jinfeng Mo, Deguang Wu, Haibo He, Panyong H. Treadmill training improves neural function recovery in rats with spinal cord injury via JAK2/STAT3 signaling pathway and attenuating apoptosis. Neuroreport. 2024-07-08. PMID:38973489. our results showed that physical treadmill training can enhance activation of jak2/stat3 signal pathway and attenuate apoptosis in the injured spinal cord, resulting in better functional recovery. 2024-07-08 2024-07-11 rat
Wei Wang, Fei Yao, Haiyuan Xing, Fan Yang, Li Ya. Exosomal miR-17-92 Cluster from BMSCs Alleviates Apoptosis and Inflammation in Spinal Cord Injury. Biochemical genetics. 2024-07-03. PMID:38961001. exosomal mir-17-92 cluster from bmscs alleviates apoptosis and inflammation in spinal cord injury. 2024-07-03 2024-07-10 rat
Wei Wang, Fei Yao, Haiyuan Xing, Fan Yang, Li Ya. Exosomal miR-17-92 Cluster from BMSCs Alleviates Apoptosis and Inflammation in Spinal Cord Injury. Biochemical genetics. 2024-07-03. PMID:38961001. spinal cord injury (sci) involves neuronal apoptosis and axonal disruption, leading to severe motor dysfunction. 2024-07-03 2024-07-10 rat
Qiuchen Wang, Lu Ge, Jiali Guo, Haijuan Zhang, Tianling Chen, Feifei Lian, Lei Li, Yun Xu, Jinyu Xu, Nuo Chen, Yu Zhang, Zhanwei Ruan, Jian Xiao, Hongyu Zhang, Liangliang Yan. Acid Neutralization by Composite Lysine Nanoparticles for Spinal Cord Injury Recovery through Mitigating Mitochondrial Dysfunction. ACS biomaterials science & engineering. 2024-06-17. PMID:38885615. after spinal cord injury (sci), significant alterations in the tissue microenvironment lead to mitochondrial dysfunction, inducing apoptosis and inhibiting the remodeling of neural circuits, thereby impeding recovery. 2024-06-17 2024-06-21 mouse
Chenyu Wu, Yu Chen, Ximiao Chen, Yekai Zhang, Xiaoying Zhao, Yuxin Deng, Chenchao Li, Di Zhang, Xiaolei Zhang, Sheng Wan. 20-Deoxyingenol Activates Mitophagy Through TFEB and Promotes Functional Recovery After Spinal Cord Injury. Molecular neurobiology. 2024-06-12. PMID:38865079. our research results show that 20-doi significantly improves the apoptosis of neural cells after tbhp stimulation and functional recovery after spinal cord injury. 2024-06-12 2024-06-14 rat
Chenyu Wu, Yu Chen, Ximiao Chen, Yekai Zhang, Xiaoying Zhao, Yuxin Deng, Chenchao Li, Di Zhang, Xiaolei Zhang, Sheng Wan. 20-Deoxyingenol Activates Mitophagy Through TFEB and Promotes Functional Recovery After Spinal Cord Injury. Molecular neurobiology. 2024-06-12. PMID:38865079. in addition, mitophagy, tfeb levels, and apoptosis are related to the mechanism of 20-doi treatment for spinal cord injury. 2024-06-12 2024-06-14 rat
Weijun Huang, Depeng Wu, Chaoyang Cai, Hui Yao, Zhenming Tian, Yang Yang, Mao Pang, Limin Rong, Bin Li. Corrigendum to "Inhibition of MST1 ameliorates neuronal apoptosis via GSK3β/β-TrCP/NRF2 pathway in spinal cord injury accompanied by diabetes" [Redox Biol. 71C (2024) 103104]. Redox biology. 2024-05-28. PMID:38806302. corrigendum to "inhibition of mst1 ameliorates neuronal apoptosis via gsk3β/β-trcp/nrf2 pathway in spinal cord injury accompanied by diabetes" [redox biol. 2024-05-28 2024-06-03 Not clear
Bo Deng, Xuegang He, Zhaoheng Wang, Jihe Kang, Guangzhi Zhang, Lei Li, Xuewen Kan. HSP70 protects PC12 cells against TBHP-induced apoptosis and oxidative stress by activating the Nrf2/HO-1 signaling pathway. In vitro cellular & developmental biology. Animal. 2024-05-28. PMID:38807023. hsp70 exhibits neuroprotective, antioxidant, and anti-apoptotic properties, which are crucial in preventing spinal cord injury (sci) induced by oxidative stress and apoptosis. 2024-05-28 2024-06-03 Not clear
Mingyu Bai, Yang Cui, Zelin Sang, Shuang Gao, Haosen Zhao, Xifan Me. Zinc ions regulate mitochondrial quality control in neurons under oxidative stress and reduce PANoptosis in spinal cord injury models via the Lgals3-Bax pathway. Free radical biology & medicine. vol 221. 2024-05-25. PMID:38782079. spinal cord injury is a serious traumatic nervous system disorder characterized by extensive neuronal apoptosis. 2024-05-25 2024-05-27 Not clear
Hassan Reda Hassan Elsayed, Eyad Mohamed Tolba Ali, Mohammed Rami Rabei, Eman Mohamad El Nashar, Mansour Abdullah Alghamdi, Norah Saeed Al-Zahrani, Shaker Hassan Alshehri, Rashid A Aldahhan, Amira Ibrahim Mors. Angiotensin II Type 1 receptor blockade attenuates the neuropathological changes in the spinal cords of diabetic rats with modulation of nuclear factor erythroid 2-related factor 2/ heme oxygenase 1 system. Tissue & cell. vol 88. 2024-05-25. PMID:38795506. after two months, the pathological alteration in the spinal cord was investigated, and an immunohistochemical study was performed for neuronal, astrocytic, and microglial markers; nuclear protein (neun), glial fibrillary acidic protein (gfap), and ionized calcium-binding adaptor molecule 1 (iba1), respectively, and for an apoptosis marker; caspase-3, and the inflammatory marker; nuclear factor kappa b (nf-kb) signaling, heme oxygenase-1 (ho-1) and nuclear factor erythroid 2-related factor 2 (nrf2); physiological antioxidant system. 2024-05-25 2024-05-31 rat
Hassan Reda Hassan Elsayed, Eyad Mohamed Tolba Ali, Mohammed Rami Rabei, Eman Mohamad El Nashar, Mansour Abdullah Alghamdi, Norah Saeed Al-Zahrani, Shaker Hassan Alshehri, Rashid A Aldahhan, Amira Ibrahim Mors. Angiotensin II Type 1 receptor blockade attenuates the neuropathological changes in the spinal cords of diabetic rats with modulation of nuclear factor erythroid 2-related factor 2/ heme oxygenase 1 system. Tissue & cell. vol 88. 2024-05-25. PMID:38795506. the results showed that losartan caused recovery of spinal cord changes, by inhibiting the microglial and astrocytic activation, suppressing neuronal apoptosis and nf-kb expression with activation of nrf2/ho-1 (p<0.0005). 2024-05-25 2024-05-31 rat
Hassan Reda Hassan Elsayed, Eyad Mohamed Tolba Ali, Mohammed Rami Rabei, Eman Mohamad El Nashar, Mansour Abdullah Alghamdi, Norah Saeed Al-Zahrani, Shaker Hassan Alshehri, Rashid A Aldahhan, Amira Ibrahim Mors. Angiotensin II Type 1 receptor blockade attenuates the neuropathological changes in the spinal cords of diabetic rats with modulation of nuclear factor erythroid 2-related factor 2/ heme oxygenase 1 system. Tissue & cell. vol 88. 2024-05-25. PMID:38795506. it is suggested, herein, that losartan can suppress diabetes-induced glial activation, inflammation, neuronal apoptosis, and oxidative stress in the spinal cord; the mechanisms that may underlie the role of at1 antagonism in suppressing diabetic neuropathic pain. 2024-05-25 2024-05-31 rat
Jiaxian Weng, Le Wang, Kai Wang, Haitao Su, Dan Luo, Haimei Yang, Yaqian Wen, Qiduan Wu, Xing L. Correction: Tauroursodeoxycholic Acid Inhibited Apoptosis and Oxidative Stress in H2O2-Induced BMSC Death via Modulating the Nrf-2 Signaling Pathway: the Therapeutic Implications in a Rat Model of Spinal Cord Injury. Molecular neurobiology. 2024-05-23. PMID:38780723. correction: tauroursodeoxycholic acid inhibited apoptosis and oxidative stress in h2o2-induced bmsc death via modulating the nrf-2 signaling pathway: the therapeutic implications in a rat model of spinal cord injury. 2024-05-23 2024-05-27 rat
Rui Tan, Chunxiao Sui, Yuhang Diao, Guihong Shi, Xiaojun Hu, Zhenghao Hao, Chenyang Li, Mingyu Hao, Minghao Xie, Tao Zh. Activation of the sigma-1 receptor ameliorates neuronal ferroptosis via IRE1α after spinal cord injury. Brain research. vol 1838. 2024-05-23. PMID:38763502. however, the present study found that sig-1r activation effectively promoted the recovery of motor function in mice after spinal cord injury, attenuated neuronal apoptosis, reduced the production of pro-inflammatory cytokines and iron accumulation, and inhibited ferroptosis in spinal cord tissues following sci in mice. 2024-05-23 2024-05-27 mouse
Zhiping Qi, Su Pan, Xiaoyu Yang, Renfeng Zhang, Cheng Qin, Hongye Yan, Longchuan Zhu, Weijian Kon. Injectable Hydrogel Loaded with CDs and FTY720 Combined with Neural Stem Cells for the Treatment of Spinal Cord Injury. International journal of nanomedicine. vol 19. 2024-05-13. PMID:38736654. spinal cord injury (sci) is an incurable and disabling event that is accompanied by complex inflammation-related pathological processes, such as the production of excessive reactive oxygen species (ros) by infiltrating inflammatory immune cells and their release into the extracellular microenvironment, resulting in extensive apoptosis of endogenous neural stem cells. 2024-05-13 2024-05-27 rat
Yilin Zhou, Yuyan Bai, Peisen Zhang, Peiqing Weng, Wenxi Xi. EXPRESS: Propofol alleviates spinal cord ischemia-reperfusion injury by preserving PI3K/AKT/GIT1 axis. Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 2024-05-08. PMID:38715211. propofol can attenuate neurological dysfunction induced by sciri, decrease spinal cord tissue injury and bscb permeability in addition to suppressing cell apoptosis and inflammatory cytokines, whereas further treatment by ly294002 can partially reverse the protective effect of propofol on sciri. 2024-05-08 2024-05-27 rat
Jingjia Ye, Xihao Pan, Zhengfa Wen, Tianxin Wu, Yuting Jin, Shunxian Ji, Xianzhu Zhang, Yuanzhu Ma, Wei Liu, Chong Teng, Longguang Tang, Wei We. Injectable conductive hydrogel remodeling microenvironment and mimicking neuroelectric signal transmission after spinal cord injury. Journal of colloid and interface science. vol 668. 2024-05-02. PMID:38696992. severe spinal cord injury (sci) leads to dysregulated neuroinflammation and cell apoptosis, resulting in axonal die-back and the loss of neuroelectric signal transmission. 2024-05-02 2024-05-05 rat
Jingjia Ye, Xihao Pan, Zhengfa Wen, Tianxin Wu, Yuting Jin, Shunxian Ji, Xianzhu Zhang, Yuanzhu Ma, Wei Liu, Chong Teng, Longguang Tang, Wei We. Injectable conductive hydrogel remodeling microenvironment and mimicking neuroelectric signal transmission after spinal cord injury. Journal of colloid and interface science. vol 668. 2024-05-02. PMID:38696992. the hydrogel also led to a notable decrease in cell apoptosis and the achievement of scar-free wound healing, which saved 45.6 ± 10.8 % of spinal cord tissue in sfma@il grafting. 2024-05-02 2024-05-05 rat