| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Youping Wang, Chi Pan, Xia Zhang, Aiqi Zhao, Ying Don. Mutant NPM1 maintains RASGRP3 protein stability via interaction with MID1 to promote acute myeloid leukemia cell proliferation and autophagy. Journal of leukocyte biology. vol 113. issue 5. 2023-05-05. PMID:36826998. |
further, cck8, edu staining, immunofluorescence, and western blot were performed to explore the effect of rasgrp3 on cell proliferation and apoptosis in npm1-mutated acute myeloid leukemia. |
2023-05-05 |
2023-12-17 |
Not clear |
| Leon Katzengruber, Pascal Sander, Stefan Laufe. MKK4 Inhibitors-Recent Development Status and Therapeutic Potential. International journal of molecular sciences. vol 24. issue 8. 2023-04-28. PMID:37108658. |
mkk4 (mitogen-activated protein kinase kinase 4; also referred to as mek4) is a dual-specificity protein kinase that phosphorylates and regulates both jnk (c-jun n-terminal kinase) and p38 mapk (p38 mitogen-activated protein kinase) signaling pathways and therefore has a great impact on cell proliferation, differentiation and apoptosis. |
2023-04-28 |
2023-08-14 |
Not clear |
| Ang Cai, Pengfei Xia, Xiaokang Zhou, Yao He, Jun L. MiR-1275 Targeting SPARC Promotes Gambogic Acid-Induced Inhibition of Gastric Cancer. Biochemical genetics. 2023-04-28. PMID:37118619. |
in functional experiments, mir-1275 enhanced the influence of ga on cell apoptosis, migration, and proliferation. |
2023-04-28 |
2023-08-14 |
mouse |
| Zahra Jodari Mohammadpour, Reza Mohammadzadeh, Darya Javadrashid, Amir Baghbanzadeh, Mohammad Amin Doustvandi, Nesa Barpour, Behzad Baradara. Combination of SIX4-siRNA and temozolomide inhibits the growth and migration of A-172 glioblastoma cancer cells. Naunyn-Schmiedeberg's archives of pharmacology. 2023-04-24. PMID:37093251. |
we studied the cytotoxic effect of the six4-sirna and tmz on a-172 cells using the mtt assay investigated their effect on apoptosis and cell cycle of a-172 cells used wound healing assays to assess their effect on cell migration. |
2023-04-24 |
2023-08-14 |
Not clear |
| Dilara Akcora-Yildiz, Nurbanu Gonulkirmaz, Tulin Ozkan, Meral Beksac, Asuman Sungurogl. HIV-1 integrase inhibitor raltegravir promotes DNA damage-induced apoptosis in multiple myeloma. Chemical biology & drug design. 2023-04-24. PMID:37094820. |
raltegravir treatment for 72 h significantly decreased cell viability, increased apoptosis, and dna damage in mm cells while having minimum toxicity on cell viability of normal pbmcs approximately from 200 nm (0.2 μm; p ˂ .01 for u66 and p ˂ .0001 for nci h929 and rpmi 8226 cells). |
2023-04-24 |
2023-08-14 |
human |
| Yanhua Zuo, Huaheng Xu, Yanxia Li, Zongfang Zhang, Ran Tao, Manxiang Wan. Hsa_circ_0007707 participates in PDE3B-mediated apoptosis inhibition and inflammation promotion in fibroblast-like synoviocytes. International immunopharmacology. vol 119. 2023-04-22. PMID:37086679. |
effects of circ_0007707 silencing on cell proliferation and apoptosis were evaluated using cell counting kit-8, 5-ethynyl-2'-deoxyuridine (edu), and flow cytometry assays. |
2023-04-22 |
2023-08-14 |
Not clear |
| Yao Guo, Qin Zhao, Yingying Tian, Yuanyuan Liu, Ziyi Yan, Changhu Xue, Jingfeng Wan. Study on the effects of the different polar group of EPA-enriched phospholipids on the proliferation and apoptosis in 95D cells. Marine life science & technology. vol 3. issue 4. 2023-04-19. PMID:37073266. |
our results showed that epa-pc effectively inhibited proliferative activity and promoted apoptosis of 95d cells in a dose-dependent manner, while epa-pe had no effect on cell proliferation, although it slightly promoted apoptosis. |
2023-04-19 |
2023-08-14 |
Not clear |
| Roya Kishani Farahani, Ehsan Nazemalhosseini Mojarad, Hamid Reza Soleimanpour-Lichae. The SW480 cell line, overexpressing PIWIL2 gene, maintains the expression of stemness and proliferation genes in the mice xenografts. Gastroenterology and hepatology from bed to bench. vol 16. issue 1. 2023-04-18. PMID:37070109. |
this study aims to confirm previous fundamental in vitro findings about the piwil2 gene by investigating the effects of its overexpression on cell cycle, proliferation, apoptosis, and stem cell expression markers in colorectal cancer cells (crc cells) at in vivo level. |
2023-04-18 |
2023-08-14 |
mouse |
| Huan Wang, Ming Shi, Jia Wan, Hong Y. The increased expression of cytokeratin 13 leads to an increase in radiosensitivity of nasopharyngeal carcinoma HNE-3 cells by upregulating ERRFI1. IUBMB life. 2023-04-18. PMID:37070291. |
the effects of ck13 overexpression on cell viability and apoptosis under radiotherapy conditions were evaluated using the cck-8 assay, immunofluorescence, and western blotting (wb). |
2023-04-18 |
2023-08-14 |
human |
| Huan Wang, Ming Shi, Jia Wan, Hong Y. The increased expression of cytokeratin 13 leads to an increase in radiosensitivity of nasopharyngeal carcinoma HNE-3 cells by upregulating ERRFI1. IUBMB life. 2023-04-18. PMID:37070291. |
the effects of errfi1 on cell viability, cell apoptosis, cell cycle, and the related key genes were further evaluated using cck-8, immunofluorescence, flow cytometry, quantitative polymerase chain reaction and wb. |
2023-04-18 |
2023-08-14 |
human |
| Yingjun Zhu, Min Zhang, Jiayu Wang, Qingxiu Wan. Knocking down Trim47 ameliorated sevoflurane-induced neuronal cell injury and cognitive impairment in rats. Experimental brain research. 2023-04-17. PMID:37067562. |
flow cytometry was used to study the effect of knockdown of trim47 on cell apoptosis. |
2023-04-17 |
2023-08-14 |
rat |
| Xiao Wu, Zhongyi Zeng, Kai Peng, Da Ren, Lei Zhan. Regulatory mechanism of DHRS2-modified human umbilical cord mesenchymal stem cells-derived exosomes in prostate cancer cell proliferation and apoptosis. Tissue & cell. vol 82. 2023-04-15. PMID:37060745. |
du145 cells were selected for in vitro study to further study the effects of dhrs2-modified exos on cell proliferation and apoptosis. |
2023-04-15 |
2023-08-14 |
human |
| Christopher Simon, Tomoko Soga, Ishwar Parha. Kisspeptin-10 Mitigates α-Synuclein-Mediated Mitochondrial Apoptosis in SH-SY5Y-Derived Neurons via a Kisspeptin Receptor-Independent Manner. International journal of molecular sciences. vol 24. issue 7. 2023-04-13. PMID:37047030. |
recapitulating the specificity observed on cell viability, exogenously administered kp-10 (0.1 µm) substantially suppressed wild-type and e46k mutant α-syn-mediated apoptosis and mitochondrial depolarization in cholinergic differentiated neurons. |
2023-04-13 |
2023-08-14 |
human |
| Omar Noman, Fahd A Nasr, Mohammad Z Ahmed, Md Tabish Rehman, Wajhul Qamar, Ali S Alqahtani, Sebastian Guenthe. Assessment of the Anticancer Effect of Chlorojanerin Isolated from Molecules (Basel, Switzerland). vol 28. issue 7. 2023-04-13. PMID:37049823. |
the effects of chlorojanerin on cell cytotoxicity, cell cycle arrest, and cell apoptosis were examined using mtt assay, propidium iodide staining, and fitc annexin v assay. |
2023-04-13 |
2023-08-14 |
Not clear |
| J Mao, Q Lu, P Li, S Shi, J Li, Y Li, S Chen, X Xi. CCDC3 Gene Regulates the Proliferation of Breast Cancer Cells. Bulletin of experimental biology and medicine. 2023-04-13. PMID:37052857. |
cell counting kit-8 and clone formation assay were used to detect the effects of ccdc3 knockdown on cell viability; flow cytometry was used to detect the effects of ccdc3 knockdown on cell apoptosis and cell cycle. |
2023-04-13 |
2023-08-14 |
human |
| Katarzyna Jaskiewicz, Magdalena Maleszka-Kurpiel, Andrzej Michalski, Rafal Ploski, Malgorzata Rydzanicz, Marzena Gajeck. Non-allergic eye rubbing is a major behavioral risk factor for keratoconus. PloS one. vol 18. issue 4. 2023-04-13. PMID:37053215. |
eye-rubbing causes ce damage and triggers cellular stress which through its influence on cell apoptosis, migration, and adhesion affects the ktcn phenotype. |
2023-04-13 |
2023-08-14 |
Not clear |
| Minglei Bi, Yonghong Qin, Liangtao Zhao, Xuanfen Zhan. Edaravone promotes viability of random skin flaps via activating PI3K/Akt/mTOR signalling pathway-mediated enhancement of autophagy. International wound journal. 2023-04-12. PMID:37042039. |
on one hand, 3-ma reversed the effects of eda on cell viability, oxidative stress and apoptosis via inhibiting autophagy. |
2023-04-12 |
2023-08-14 |
mouse |
| Jiayi Wang, Keizo Matsushita, Jianyong Zhong, Li-Jun Ma, Hai-Chun Yang, Agnes B Fog. Low-Dose Erythropoietin Amplifies Beneficial Effects of Angiotensin II Blockade on Glomerulosclerosis. Laboratory investigation; a journal of technical methods and pathology. vol 103. issue 2. 2023-04-11. PMID:37039147. |
glomerular endothelial cells and podocytes were cultured to evaluate the effects of da on cell migration, apoptosis, and akt signaling. |
2023-04-11 |
2023-08-14 |
mouse |
| Li Pan, Tianjiao E, Chengyu Xu, Xiapu Fan, Jiajia Xia, Yan Liu, Jiawei Liu, Jinpeng Zhao, Nan Bao, Yuan Zhao, Hui Sun, Guixin Qin, Mohammed Hamdy Farou. The apoptotic effects of soybean agglutinin were induced through three different signal pathways by down-regulating cytoskeleton proteins in IPEC-J2 cells. Scientific reports. vol 13. issue 1. 2023-04-08. PMID:37031286. |
we aimed to evaluate the effects of sba on cell apoptosis and the expression of the cytoskeletal protein (krt8, krt18 and acta), reveal the roles of these cytoskeletal proteins or their combinations on sba-induced cell apoptosis in ipec-j2 cell line, evaluate the influences of sba on the mitochondria, endoplasmic reticulum stress and death receptor-mediated apoptosis signal pathway and to show the roles of krt8, krt18 and acta in different apoptosis signal pathways induced by sba. |
2023-04-08 |
2023-08-14 |
Not clear |
| Li Pan, Tianjiao E, Chengyu Xu, Xiapu Fan, Jiajia Xia, Yan Liu, Jiawei Liu, Jinpeng Zhao, Nan Bao, Yuan Zhao, Hui Sun, Guixin Qin, Mohammed Hamdy Farou. The apoptotic effects of soybean agglutinin were induced through three different signal pathways by down-regulating cytoskeleton proteins in IPEC-J2 cells. Scientific reports. vol 13. issue 1. 2023-04-08. PMID:37031286. |
the degree of effect of three cytoskeleton proteins on cell apoptosis was acta > krt8 > krt18. |
2023-04-08 |
2023-08-14 |
Not clear |