| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuming Cao, Zhenlie Chen, Ming Zhang, Lei Shi, Songling Qin, Dan Lv, Danyang Li, Ling Ma, Yuanzhen Zhan. Maternal exposure to bisphenol A induces fetal growth restriction via upregulating the expression of estrogen receptors. Chemosphere. vol 287. issue Pt 3. 2021-11-26. PMID:34537452. |
in conclusion, bpa promotes estrogen production and cell apoptosis in bewo cells via upregulating er expression, leading to fgr. |
2021-11-26 |
2023-08-13 |
human |
| Lynda K Harris, Priyadarshini Pantham, Hannah E J Yong, Anita Pratt, Anthony J Borg, Ian Crocker, Melissa Westwood, John Aplin, Bill Kalionis, Padma Murth. The role of insulin-like growth factor 2 receptor-mediated homeobox gene expression in human placental apoptosis, and its implications in idiopathic fetal growth restriction. Molecular human reproduction. vol 25. issue 9. 2020-07-14. PMID:31418778. |
it is well known that placentas from women with fgr exhibit reduced cell growth, elevated levels of apoptosis and perturbed expression of the growth factors, cytokines and the homeobox gene family of transcription factors. |
2020-07-14 |
2023-08-13 |
human |
| Lynda K Harris, Priyadarshini Pantham, Hannah E J Yong, Anita Pratt, Anthony J Borg, Ian Crocker, Melissa Westwood, John Aplin, Bill Kalionis, Padma Murth. The role of insulin-like growth factor 2 receptor-mediated homeobox gene expression in human placental apoptosis, and its implications in idiopathic fetal growth restriction. Molecular human reproduction. vol 25. issue 9. 2020-07-14. PMID:31418778. |
this is the first study linking igf2r placental expression with changes in the expression of homeobox genes that control cellular signalling pathways responsible for increased trophoblast cell apoptosis, which is a characteristic feature of fgr. |
2020-07-14 |
2023-08-13 |
human |
| C Paules, A P Dantas, J Miranda, F Crovetto, E Eixarch, V Rodriguez-Sureda, C Dominguez, G Casu, C Rovira, A Nadal, F Crispi, E Gratacó. Premature placental aging in term small-for-gestational-age and growth-restricted fetuses. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology. vol 53. issue 5. 2019-12-24. PMID:30125412. |
to perform a comprehensive assessment of the placental aging process in small term fetuses classified as being small-for-gestational age (sga) or having fetal growth restriction (fgr) through analysis of senescence and apoptosis markers. |
2019-12-24 |
2023-08-13 |
Not clear |
| Alan D Bolnick, Jay M Bolnick, Hamid-Reza Kohan-Ghadr, Brian A Kilburn, Michael Hertz, Jing Dai, Sascha Drewlo, D Randall Arman. Nifedipine Prevents Apoptosis of Alcohol-Exposed First-Trimester Trophoblast Cells. Alcoholism, clinical and experimental research. vol 42. issue 1. 2019-08-14. PMID:29048755. |
ethanol (etoh) induces apoptosis of human placental trophoblast cells, possibly disrupting placentation and contributing to fgr in fasd. |
2019-08-14 |
2023-08-13 |
human |
| Anna Karynna Alves de Alencar Rocha, Beth J Allison, Tamara Yawno, Graeme R Polglase, Amy E Sutherland, Atul Malhotra, Graham Jenkin, Margie Castillo-Melendez, Suzanne L Mille. Early- versus Late-Onset Fetal Growth Restriction Differentially Affects the Development of the Fetal Sheep Brain. Developmental neuroscience. vol 39. issue 1-4. 2018-02-13. PMID:28273661. |
neun-positive neuronal cell counts in the cortex were not different across groups; however, the morphology of neuronal cells was different in response to placental insufficiency, most notable in the early-onset fgr fetuses, but it was late-onset fgr that induced caspase-3-positive apoptosis within the cortex. |
2018-02-13 |
2023-08-13 |
Not clear |
| Yan P Wang, Xu Chen, Zhi K Zhang, Hong Y Cui, Peng Wang, Yue Wan. Increased renal apoptosis and reduced renin-angiotensin system in fetal growth restriction. Journal of the renin-angiotensin-aldosterone system : JRAAS. vol 17. issue 3. 2017-04-17. PMID:27534427. |
the purpose of the study was to characterize changes in apoptosis and the renin-angiotensin system (ras) in fetal growth restriction (fgr). |
2017-04-17 |
2023-08-13 |
Not clear |
| Hui Chen, Zhen-Wei Liang, Zhen-Hua Wang, Jian-Ping Zhang, Bo Hu, Xiang-Bin Xing, Wei-Bin Ca. Akt Activation and Inhibition of Cytochrome C Release: Mechanistic Insights into Leptin-promoted Survival of Type II Alveolar Epithelial Cells. Journal of cellular biochemistry. vol 116. issue 10. 2016-05-31. PMID:25833759. |
taken together, our data suggested that leptin enhances the maturity of fetal lungs by mediating the regulation of caspase-3 and -9 during hypoxia-induced apoptosis of type ii aecs and provide support for the potential of leptin as a therapeutic agent for promoting lung development in fgr. |
2016-05-31 |
2023-08-13 |
rat |
| T P H Nguyen, H E J Yong, T Chollangi, A J Borg, S P Brennecke, P Murth. Placental vitamin D receptor expression is decreased in human idiopathic fetal growth restriction. Journal of molecular medicine (Berlin, Germany). vol 93. issue 7. 2016-03-24. PMID:25716068. |
our study aimed at determining placental vdr expression in fgr and gestation-matched control (gmc) pregnancies and identifying the actions of vdr in trophoblast differentiation and apoptosis. |
2016-03-24 |
2023-08-13 |
human |
| T P H Nguyen, H E J Yong, T Chollangi, A J Borg, S P Brennecke, P Murth. Placental vitamin D receptor expression is decreased in human idiopathic fetal growth restriction. Journal of molecular medicine (Berlin, Germany). vol 93. issue 7. 2016-03-24. PMID:25716068. |
significant decreases in vdr mrna expression (p = 0.0005) and protein expression (p = 0.0003) were observed in the fgr samples, while vdr inactivation, which showed markers for differentiation, cell attachment and apoptosis, was significantly increased. |
2016-03-24 |
2023-08-13 |
human |
| T P H Nguyen, H E J Yong, T Chollangi, A J Borg, S P Brennecke, P Murth. Placental vitamin D receptor expression is decreased in human idiopathic fetal growth restriction. Journal of molecular medicine (Berlin, Germany). vol 93. issue 7. 2016-03-24. PMID:25716068. |
thus, decreased placental vdr may contribute to uncontrolled premature differentiation and apoptosis of trophoblasts that are characteristics of idiopathic fgr pregnancies. |
2016-03-24 |
2023-08-13 |
human |
| Padma Murthi, Hannah E J Yong, Thy P H Ngyuen, Stacey Ellery, Harmeet Singh, Rahana Rahman, Hayley Dickinson, David W Walker, Miranda Davies-Tuck, Euan M Wallace, Peter R Ebelin. Role of the Placental Vitamin D Receptor in Modulating Feto-Placental Growth in Fetal Growth Restriction and Preeclampsia-Affected Pregnancies. Frontiers in physiology. vol 7. 2016-02-29. PMID:26924988. |
our own studies demonstrate that the vitamin d receptor (vdr) is significantly decreased in placentae from human pregnancies complicated by fgr and contributes to abnormal placental trophoblast apoptosis and differentiation and regulation of cell-cycle genes in vitro. |
2016-02-29 |
2023-08-13 |
human |
| Rachel Sheridan, Chethan Belludi, Jane Khoury, Jerzy Stanek, Stuart Handwerge. FOXO1 expression in villous trophoblast of preeclampsia and fetal growth restriction placentas. Histology and histopathology. vol 30. issue 2. 2015-11-02. PMID:25202916. |
oxidative stress and increased apoptosis are implicated in the pathogenesis of many disorders of pregnancy, including preeclampsia (pe) and fetal growth restriction (fgr). |
2015-11-02 |
2023-08-13 |
Not clear |
| Rachel Sheridan, Chethan Belludi, Jane Khoury, Jerzy Stanek, Stuart Handwerge. FOXO1 expression in villous trophoblast of preeclampsia and fetal growth restriction placentas. Histology and histopathology. vol 30. issue 2. 2015-11-02. PMID:25202916. |
since the transcription factor foxo1 (forkhead box protein o1) is implicated in the regulation of a variety of cellular processes, including resistance to oxidative stress, apoptosis and morphogenesis of the placenta, we examined whether foxo1 expression is abnormal in placentas from patients with pe or fgr. |
2015-11-02 |
2023-08-13 |
Not clear |
| Zivanit Ergaz, Claire Guillemin, Meytal Neeman-Azulay, Liza Weinstein-Fudim, Christopher J Stodgell, Richard K Miller, Moshe Szyf, Asher Orno. Placental oxidative stress and decreased global DNA methylation are corrected by copper in the Cohen diabetic rat. Toxicology and applied pharmacology. vol 276. issue 3. 2014-06-07. PMID:24593922. |
hsd induced fgr and fetal oxidative stress, more prominent in the cds, that was alleviated more effectively by copper than by the anti-oxidant vitamins c and e. our aim was to evaluate the impact of copper or the anti-oxidant tempol on placental size, protein content, oxidative stress, apoptosis and total dna methylation. |
2014-06-07 |
2023-08-12 |
rat |
| C L Whitehead, S P Walker, M Lappas, S Ton. Circulating RNA coding genes regulating apoptosis in maternal blood in severe early onset fetal growth restriction and pre-eclampsia. Journal of perinatology : official journal of the California Perinatal Association. vol 33. issue 8. 2014-03-11. PMID:23429544. |
to determine whether the intrinsic apoptosis pathway is differentially expressed in placenta and maternal blood in severe preterm fetal growth restriction (fgr) and pre-eclampsia (pe), and to examine whether circulating rna in maternal blood may be potential biomarkers. |
2014-03-11 |
2023-08-12 |
Not clear |
| Johanna Selvaratnam, Haiyan Guan, James Koropatnick, Kaiping Yan. Metallothionein-I- and -II-deficient mice display increased susceptibility to cadmium-induced fetal growth restriction. American journal of physiology. Endocrinology and metabolism. vol 305. issue 6. 2013-11-15. PMID:23880315. |
the present data also suggest that increased apoptosis and reduced glut1 expression in the placenta contribute to the molecular mechanisms underlying cadmium-induced fgr. |
2013-11-15 |
2023-08-12 |
mouse |
| M Desforges, L Parsons, M Westwood, C P Sibley, S L Greenwoo. Taurine transport in human placental trophoblast is important for regulation of cell differentiation and survival. Cell death & disease. vol 4. 2013-08-23. PMID:23519128. |
trophoblast differentiation was compromised in taut-deficient cells, and susceptibility of these cells to an inflammatory cytokine that is elevated in fgr was increased, evidenced by elevated levels of apoptosis. |
2013-08-23 |
2023-08-12 |
human |
| Zhen-Yan Chen, Qi Wang, Guang-Ying Huan. [Effect of Bushen Yiqi Huoxue Recipe on placental trophoblast apoptosis in fetal growth restricted pregnant rat]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine. vol 30. issue 6. 2013-01-24. PMID:20815277. |
to observe the effect of bushen yiqi huoxue recipe (byhr, a chinese medical prescription for reinforcing shen, replenishing qi and promoting blood circulation) on placental trophoblast apoptosis in fetal growth restricted (fgr) pregnant rat for the sake of explore its mechanism of action in treating fgr. |
2013-01-24 |
2023-08-12 |
rat |
| Hua Chen, Zhong-ying Da. [Roles of placental cellular apoptosis and bcl-2 expression in fetal growth restriction with unclear etiologies]. Zhonghua fu chan ke za zhi. vol 43. issue 7. 2011-10-28. PMID:19080514. |
to investigate the roles of placental cellular apoptosis and bcl-2 gene expression in fetal growth restriction (fgr) with unclear etiologies. |
2011-10-28 |
2023-08-12 |
Not clear |