| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Linmei Zheng, Rong Tang, Junbo Fang, Haoyue Hu, Fiaz Ahmad, Qiong Tang, Jinfu Liu, Mei Zhong, Jing L. Circular RNA hsa_circ_0081343 modulates trophoblast autophagy through Rbm8a nuclear translocation. Placenta. vol 158. 2024-10-16. PMID:39413593. |
recent studies reported significant reduction of hsa_circ_0081343 in human placenta developed in fgr and is involved in cell migration, invasion, and apoptosis of trophoblast by acting as microrna sponges. |
2024-10-16 |
2024-10-19 |
human |
| Song Zhang, Mitchell C Lock, Michelle Tie, I Caroline McMillen, Kimberley J Botting, Janna L Morriso. Cardiac programming in the placentally restricted sheep fetus in early gestation. The Journal of physiology. 2024-07-08. PMID:38975864. |
fgr did not change cardiomyocyte proliferation during early gestation but did result in increased apoptosis and markers of autophagy in the fetal heart, which may result in the decreased endowment of cardiomyocytes observed in late gestation. |
2024-07-08 |
2024-07-11 |
human |
| Qiang Ma, Lu Zheng, Hao Cheng, Xiaoyang Li, Zhining Liu, Peng Gon. PDCD4-induced oxidative stress through FGR/NF-κB axis in rectal cancer radiotherapy-induced AKI. International immunopharmacology. vol 132. 2024-04-06. PMID:38581987. |
in vitro experiments demonstrated that pdcd4 induced apoptosis in renal tubular cells by promoting fgr expression, which activated the nf-κb signaling pathway and triggered an oxidative stress response. |
2024-04-06 |
2024-04-10 |
mouse |
| Lauren T Gallagher, James Bardill, Carmen C Sucharov, Clyde J Wright, Anis Karimpour-Fard, Miguel Zarate, Courtney Breckenfelder, Kenneth W Liechty, S Christopher Derderia. Dysregulation of miRNA-mRNA expression in fetal growth restriction in a caloric restricted mouse model. Scientific reports. vol 14. issue 1. 2024-03-06. PMID:38448721. |
thus, a maternal caloric restriction mouse model of fgr results in aberrant microrna-regulated molecular pathways associated with angiogenesis, oxidative stress, signal transduction, apoptosis, and cell differentiation. |
2024-03-06 |
2024-03-09 |
mouse |
| Hao Zhang, Xia Zha, Bei Zhang, Yi Zheng, Mabrouk Elsabagh, Hongrong Wang, Mengzhi Wan. Gut microbiota contributes to bisphenol A-induced maternal intestinal and placental apoptosis, oxidative stress, and fetal growth restriction in pregnant ewe model by regulating gut-placental axis. Microbiome. vol 12. issue 1. 2024-02-16. PMID:38365714. |
previous studies on pregnant ewes revealed that bpa exposure causes placental apoptosis and oxidative stress (os) and decreases placental efficiency, consequently leading to fgr. |
2024-02-16 |
2024-02-19 |
Not clear |
| Mengyao Wu, Junyu He, Yetao Chen, Fangzhu Wan, Hongbo Tang, Chenghong Yin, Haibo He, Huifan Yu, Chengfu Yua. Biomarkers for Diagnosing and Treating Fetal Growth Restriction. Current medicinal chemistry. 2023-11-03. PMID:37921170. |
this review focuses on the prediction and diagnosis of fgr, as well as the significance of biomarkers for fgr, such as those related to gene regulation, apoptosis, mitochondrial function, and inflammation. |
2023-11-03 |
2023-11-08 |
Not clear |
| Lauren Sayres, Amanda R Flockton, Shuhan Ji, Carla Rey Diaz, Diane L Gumina, Emily J S. Angiogenic Function of Human Placental Endothelial Cells in Severe Fetal Growth Restriction Is Not Rescued by Individual Extracellular Matrix Proteins. Cells. vol 12. issue 19. 2023-10-13. PMID:37830553. |
ecs were isolated from human placentae, either control or affected by severe fgr, and subjected to a series of experiments to interrogate the role of ecm proteins on adhesion, proliferation, migration, and apoptosis. |
2023-10-13 |
2023-10-15 |
human |
| Lauren Sayres, Amanda R Flockton, Shuhan Ji, Carla Rey Diaz, Diane L Gumina, Emily J S. Angiogenic Function of Human Placental Endothelial Cells in Severe Fetal Growth Restriction Is Not Rescued by Individual Extracellular Matrix Proteins. Cells. vol 12. issue 19. 2023-10-13. PMID:37830553. |
differences in adhesion and apoptosis between control and fgr ecs were not evident. |
2023-10-13 |
2023-10-15 |
human |
| Kwang-Youn Kim, Jae Dong Son, Su-Jin Hwang, Jong Kwang Lee, Jae Young Park, Kwang Il Park, Tae Woo O. Fermented Glutinous Rice Extract Mitigates DSS-Induced Ulcerative Colitis by Alleviating Intestinal Barrier Function and Improving Gut Microbiota and Inflammation. Antioxidants (Basel, Switzerland). vol 12. issue 2. 2023-02-25. PMID:36829894. |
herein, we determined the effects of fermented glutinous rice (fgr) on the expression of tight junction proteins and levels of inflammation and apoptosis in the dextran sodium sulfate (dss)-induced acute colitis model. |
2023-02-25 |
2023-08-14 |
mouse |
| Kwang-Youn Kim, Jae Dong Son, Su-Jin Hwang, Jong Kwang Lee, Jae Young Park, Kwang Il Park, Tae Woo O. Fermented Glutinous Rice Extract Mitigates DSS-Induced Ulcerative Colitis by Alleviating Intestinal Barrier Function and Improving Gut Microbiota and Inflammation. Antioxidants (Basel, Switzerland). vol 12. issue 2. 2023-02-25. PMID:36829894. |
furthermore, fgr treatment inhibited apoptosis by reducing the activity of caspase-3 and the ratio of bcl-2 associated x (bax)/b-cell lymphoma 2 (bcl-2). |
2023-02-25 |
2023-08-14 |
mouse |
| Kwang-Youn Kim, Jae Dong Son, Su-Jin Hwang, Jong Kwang Lee, Jae Young Park, Kwang Il Park, Tae Woo O. Fermented Glutinous Rice Extract Mitigates DSS-Induced Ulcerative Colitis by Alleviating Intestinal Barrier Function and Improving Gut Microbiota and Inflammation. Antioxidants (Basel, Switzerland). vol 12. issue 2. 2023-02-25. PMID:36829894. |
collectively, fgr treatment protected the intestinal barrier from dysfunction and inhibited inflammation and apoptosis in dss-induced colitis. |
2023-02-25 |
2023-08-14 |
mouse |
| Hao Zhang, Yi Zheng, Xiaoyun Liu, Xia Zha, Mabrouk Elsabagh, Yi Ma, Honghua Jiang, Hongrong Wang, Mengzhi Wan. Autophagy attenuates placental apoptosis, oxidative stress and fetal growth restriction in pregnant ewes. Environment international. vol 173. 2023-02-25. PMID:36841186. |
exposure to bpa during gestation resulted in placental insufficiency, fetal growth restriction (fgr), autophagy, endoplasmic reticulum stress (ers), mitochondrial dysfunction, os, and apoptosis in type a placentomes. |
2023-02-25 |
2023-08-14 |
cat |
| Ignacio Valenzuela, Katerina Zapletalova, Marnel Greyling, Yannick Regin, Andre Gie, David Basurto, Jan Deprest, Johannes van der Merw. Fetal Growth Restriction Impairs Lung Function and Neurodevelopment in an Early Preterm Rabbit Model. Biomedicines. vol 11. issue 1. 2023-01-21. PMID:36672647. |
in fgr brains, cell density was globally reduced, with higher apoptosis in selected areas. |
2023-01-21 |
2023-08-14 |
rabbit |
| Zhuomin Huang, Litong Zhu, Quanfu Zhang, Depeng Zhao, Jilong Ya. Circular RNA hsa-circ-0005238 enhances trophoblast migration, invasion and suppresses apoptosis Frontiers in medicine. vol 9. 2022-10-31. PMID:36314002. |
circular rna hsa-circ-0005238 enhances trophoblast migration, invasion and suppresses apoptosis fetal growth restriction (fgr) is attributed to various maternal, fetal, and placental factors. |
2022-10-31 |
2023-08-14 |
Not clear |
| Tomasz Gęca, Aleksandra Stupak, Robert Nawrot, Anna Goździcka-Józefiak, Anna Kwaśniewska, Wojciech Kwaśniewsk. Placental proteome in late‑onset of fetal growth restriction. Molecular medicine reports. vol 26. issue 6. 2022-10-20. PMID:36263610. |
in the fgr placental proteome, other detected proteins were mostly involved in response to oxidative stress, cellular oxidation and detoxication, apoptosis, hemostatic and catabolic processes, energy transduction protein interactions, cell proliferation, differentiation and intracellular signaling. |
2022-10-20 |
2023-08-14 |
Not clear |
| Jiawen Cui, Xinyi Kang, Yanxing Shan, Mingjin Zhang, Ying Gao, Wei Wu, Liping Che. miR-1227-3p participates in the development of fetal growth restriction via regulating trophoblast cell proliferation and apoptosis. Scientific reports. vol 12. issue 1. 2022-04-18. PMID:35430618. |
taken together, mir-1227-3p may participate in the development of fgr via regulating trophoblast cell proliferation and apoptosis by targeting genes involved in the insulin pathway. |
2022-04-18 |
2023-08-13 |
Not clear |
| Hua-Long Zhu, Li-Min Dai, Yong-Wei Xiong, Xue-Ting Shi, Wei-Bo Liu, Yi-Ting Fu, Guo-Xiang Zhou, Shuang Zhang, Lan Gao, Cheng Zhang, Ling-Li Zhao, Xiao-Feng Xu, Yi-Chao Huang, De-Xiang Xu, Hua Wan. Gestational exposure to environmental cadmium induces placental apoptosis and fetal growth restriction via Parkin-modulated MCL-1 degradation. Journal of hazardous materials. vol 424. issue Pt A. 2021-12-07. PMID:34583167. |
heavy metal cadmium (cd), a classical environmental pollutant, causes placental apoptosis and fetal growth restriction (fgr), whereby the mechanism remains unclear. |
2021-12-07 |
2023-08-13 |
mouse |
| Hua-Long Zhu, Li-Min Dai, Yong-Wei Xiong, Xue-Ting Shi, Wei-Bo Liu, Yi-Ting Fu, Guo-Xiang Zhou, Shuang Zhang, Lan Gao, Cheng Zhang, Ling-Li Zhao, Xiao-Feng Xu, Yi-Chao Huang, De-Xiang Xu, Hua Wan. Gestational exposure to environmental cadmium induces placental apoptosis and fetal growth restriction via Parkin-modulated MCL-1 degradation. Journal of hazardous materials. vol 424. issue Pt A. 2021-12-07. PMID:34583167. |
here, our human case-control study firstly showed that there was a positive association of parkin mitochondrial translocation, mcl-1 reduction, placental apoptosis, and all-cause fgr. |
2021-12-07 |
2023-08-13 |
mouse |
| Hua-Long Zhu, Li-Min Dai, Yong-Wei Xiong, Xue-Ting Shi, Wei-Bo Liu, Yi-Ting Fu, Guo-Xiang Zhou, Shuang Zhang, Lan Gao, Cheng Zhang, Ling-Li Zhao, Xiao-Feng Xu, Yi-Chao Huang, De-Xiang Xu, Hua Wan. Gestational exposure to environmental cadmium induces placental apoptosis and fetal growth restriction via Parkin-modulated MCL-1 degradation. Journal of hazardous materials. vol 424. issue Pt A. 2021-12-07. PMID:34583167. |
subsequently, cd was administered to establish in vitro and in vivo models of placental apoptosis or fgr. |
2021-12-07 |
2023-08-13 |
mouse |
| Hua-Long Zhu, Li-Min Dai, Yong-Wei Xiong, Xue-Ting Shi, Wei-Bo Liu, Yi-Ting Fu, Guo-Xiang Zhou, Shuang Zhang, Lan Gao, Cheng Zhang, Ling-Li Zhao, Xiao-Feng Xu, Yi-Chao Huang, De-Xiang Xu, Hua Wan. Gestational exposure to environmental cadmium induces placental apoptosis and fetal growth restriction via Parkin-modulated MCL-1 degradation. Journal of hazardous materials. vol 424. issue Pt A. 2021-12-07. PMID:34583167. |
in conclusion, cadmium induces placental apoptosis and fgr via mtros-mediated parkin-modulated degradation of mcl-1. |
2021-12-07 |
2023-08-13 |
mouse |