| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E J Wolvetang, T J Wilson, E Sanij, J Busciglio, T Hatzistavrou, A Seth, P J Hertzog, I Kol. ETS2 overexpression in transgenic models and in Down syndrome predisposes to apoptosis via the p53 pathway. Human molecular genetics. vol 12. issue 3. 2003-09-24. PMID:12554679. |
in all circumstances of ets2 overexpression, the increased apoptosis correlated with increased p53 and alterations in downstream factors in the p53 pathway. |
2003-09-24 |
2023-08-12 |
mouse |
| Arnaud Zaldumbide, Françoise Carlotti, Philippe Pognonec, Kim E Bouluko. The role of the Ets2 transcription factor in the proliferation, maturation, and survival of mouse thymocytes. Journal of immunology (Baltimore, Md. : 1950). vol 169. issue 9. 2002-12-10. PMID:12391198. |
the proliferation and survival of these t cells are clearly affected upon apoptotic signals: glucocorticoid-induced apoptosis induces t cells from ets2 transgenic mice to continue to proliferate in vivo and to survive better ex vivo than t cells from control littermates. |
2002-12-10 |
2023-08-12 |
mouse |
| L Sevilla, A Zaldumbide, F Carlotti, M A Dayem, P Pognonec, K E Bouluko. Bcl-XL expression correlates with primary macrophage differentiation, activation of functional competence, and survival and results from synergistic transcriptional activation by Ets2 and PU.1. The Journal of biological chemistry. vol 276. issue 21. 2001-07-05. PMID:11278399. |
we demonstrate that the exogenous expression of both ets2 and pu.1 in macrophages increases the number of viable cells upon csf-1 depletion and that ets2 and pu.1 can functionally replace bcl-x(l) in inhibiting bax-induced apoptosis. |
2001-07-05 |
2023-08-12 |
Not clear |
| L Sevilla, C Aperlo, V Dulic, J C Chambard, C Boutonnet, O Pasquier, P Pognonec, K E Bouluko. The Ets2 transcription factor inhibits apoptosis induced by colony-stimulating factor 1 deprivation of macrophages through a Bcl-xL-dependent mechanism. Molecular and cellular biology. vol 19. issue 4. 1999-04-20. PMID:10082528. |
transient expression of ets2 results in the upregulation of bcl-xl but not of bcl-xs, an alternatively spliced gene product which induces apoptosis. |
1999-04-20 |
2023-08-12 |
Not clear |
| L Sevilla, C Aperlo, V Dulic, J C Chambard, C Boutonnet, O Pasquier, P Pognonec, K E Bouluko. The Ets2 transcription factor inhibits apoptosis induced by colony-stimulating factor 1 deprivation of macrophages through a Bcl-xL-dependent mechanism. Molecular and cellular biology. vol 19. issue 4. 1999-04-20. PMID:10082528. |
these results strongly suggest a novel role of ets2 in affecting apoptosis through its regulation of bcl-xl transcription. |
1999-04-20 |
2023-08-12 |
Not clear |
| L Sevilla, C Aperlo, V Dulic, J C Chambard, C Boutonnet, O Pasquier, P Pognonec, K E Bouluko. The Ets2 transcription factor inhibits apoptosis induced by colony-stimulating factor 1 deprivation of macrophages through a Bcl-xL-dependent mechanism. Molecular and cellular biology. vol 19. issue 4. 1999-04-20. PMID:10082528. |
the ets2 transcription factor inhibits apoptosis induced by colony-stimulating factor 1 deprivation of macrophages through a bcl-xl-dependent mechanism. |
1999-04-20 |
2023-08-12 |
Not clear |
| L Sevilla, C Aperlo, V Dulic, J C Chambard, C Boutonnet, O Pasquier, P Pognonec, K E Bouluko. The Ets2 transcription factor inhibits apoptosis induced by colony-stimulating factor 1 deprivation of macrophages through a Bcl-xL-dependent mechanism. Molecular and cellular biology. vol 19. issue 4. 1999-04-20. PMID:10082528. |
in the absence of csf-1, these macrophages undergo cell death by apoptosis, whereas constitutive expression of ets2 rescues these cells from cell death, and bcl-xl is upregulated. |
1999-04-20 |
2023-08-12 |
Not clear |