| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mercedes Salido, Jose Vilches, Antonio López, Godfried M Rooman. Neuropeptides bombesin and calcitonin inhibit apoptosis-related elemental changes in prostate carcinoma cell lines. Cancer. vol 94. issue 2. 2002-04-04. PMID:11900223. |
the authors previously reported that calcitonin and bombesin inhibited etoposide-induced apoptosis in these cells. |
2002-04-04 |
2023-08-12 |
Not clear |
| A S Belloni, G Albertin, M L Forneris, G G Nussdorfe. Proadrenomedullin-derived peptides as autocrine-paracrine regulators of cell growth. Histology and histopathology. vol 16. issue 4. 2002-03-21. PMID:11642745. |
these last two effects are mediated by calcitonin gene-related peptide type 1 (cgrp1) receptors coupled to the adenylate cyclase (ac)/protein kinase (pk) a-dependent cascade; 2) inhibits proliferation and enhances apoptosis of kidney mesangial cells, through the modulation of mitogen-activated pk (mapk) cascades; 3) stimulates proliferation of adrenal zona glomerulosa cells, acting via cgrp1 receptor coupled to the tyrosine kinase-dependent mapk cascade, thereby possibly being involved in the maintenance and stimulation of adrenal growth; 4) enhances proliferation of skin and mucosa epithelial cells and fibroblasts, by activating cgrp1 receptor coupled to the ac/pka signaling pathway; and 5) enhances proliferation of several tumor-cell lines through the activation of the ac/pka cascade, which suggests a potential role for adm as promoter of neoplastic growth. |
2002-03-21 |
2023-08-12 |
Not clear |
| J D Adachi, A Papaioanno. Corticosteroid-Induced osteoporosis: detection and management. Drug safety. vol 24. issue 8. 2002-01-22. PMID:11480493. |
interesting work has suggested that the bisphosphonates and calcitonin may help to prevent osteoblast apoptosis from occurring. |
2002-01-22 |
2023-08-12 |
Not clear |
| M Salido, J Vilches, A Lópe. Neuropeptides bombesin and calcitonin induce resistance to etoposide induced apoptosis in prostate cancer cell lines. Histology and histopathology. vol 15. issue 3. 2001-01-25. PMID:10963117. |
neuropeptides bombesin and calcitonin induce resistance to etoposide induced apoptosis in prostate cancer cell lines. |
2001-01-25 |
2023-08-12 |
Not clear |
| K Kanaoka, Y Kobayashi, F Hashimoto, T Nakashima, M Shibata, K Kobayashi, Y Kato, H Saka. A common downstream signaling activity of osteoclast survival factors that prevent nitric oxide-promoted osteoclast apoptosis. Endocrinology. vol 141. issue 8. 2000-08-16. PMID:10919288. |
independently from the pka activation, colony stimulating factor-1, interleukin-1beta and the receptor activator of nf-kappab ligand also protected against the apoptosis but were less effective than calcitonin. |
2000-08-16 |
2023-08-12 |
Not clear |
| I Millet, R J Phillips, R S Sherwin, S Ghosh, R E Voll, R A Flavell, A Vignery, M Rincó. Inhibition of NF-kappaB activity and enhancement of apoptosis by the neuropeptide calcitonin gene-related peptide. The Journal of biological chemistry. vol 275. issue 20. 2000-06-21. PMID:10809748. |
inhibition of nf-kappab activity and enhancement of apoptosis by the neuropeptide calcitonin gene-related peptide. |
2000-06-21 |
2023-08-12 |
mouse |
| L I Plotkin, R S Weinstein, A M Parfitt, P K Roberson, S C Manolagas, T Bellid. Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin. The Journal of clinical investigation. vol 104. issue 10. 1999-12-09. PMID:10562298. |
prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin. |
1999-12-09 |
2023-08-12 |
mouse |
| L I Plotkin, R S Weinstein, A M Parfitt, P K Roberson, S C Manolagas, T Bellid. Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin. The Journal of clinical investigation. vol 104. issue 10. 1999-12-09. PMID:10562298. |
these results suggest that the therapeutic efficacy of bps or calcitonin in diseases such as glucocorticoid-induced osteoporosis may be due, in part, to their ability to prevent osteocyte and osteoblast apoptosis. |
1999-12-09 |
2023-08-12 |
mouse |
| M Shichiri, H Kato, M Doi, F Marumo, Y Hirat. Induction of max by adrenomedullin and calcitonin gene-related peptide antagonizes endothelial apoptosis. Molecular endocrinology (Baltimore, Md.). vol 13. issue 8. 1999-09-20. PMID:10446908. |
induction of max by adrenomedullin and calcitonin gene-related peptide antagonizes endothelial apoptosis. |
1999-09-20 |
2023-08-12 |
rat |
| K S Selander, P L Härkönen, E Valve, J Mönkkönen, R Hannuniemi, H K Väänäne. Calcitonin promotes osteoclast survival in vitro. Molecular and cellular endocrinology. vol 122. issue 2. 1997-02-21. PMID:8902842. |
here we show that calcitonin also promotes the survival of rat osteoclasts in vitro, cultured either on glass or bone, by delaying the onset of apoptosis. |
1997-02-21 |
2023-08-12 |
rat |
| K S Selander, P L Härkönen, E Valve, J Mönkkönen, R Hannuniemi, H K Väänäne. Calcitonin promotes osteoclast survival in vitro. Molecular and cellular endocrinology. vol 122. issue 2. 1997-02-21. PMID:8902842. |
however, clodronate-induced apoptosis of osteoclasts could not be reversed by calcitonin and neither could calcitonin rescue osteoclasts already committed to apoptosis. |
1997-02-21 |
2023-08-12 |
rat |
| K S Selander, P L Härkönen, E Valve, J Mönkkönen, R Hannuniemi, H K Väänäne. Calcitonin promotes osteoclast survival in vitro. Molecular and cellular endocrinology. vol 122. issue 2. 1997-02-21. PMID:8902842. |
our results show that at least in vitro calcitonin protects osteoclasts from apoptosis and suggest that it regulates the onset of apoptosis. |
1997-02-21 |
2023-08-12 |
rat |
| H Sakuta, K Inaba, S Muramats. Calcitonin gene-related peptide enhances apoptosis of thymocytes. Journal of neuroimmunology. vol 67. issue 2. 1996-09-18. PMID:8765332. |
calcitonin gene-related peptide enhances apoptosis of thymocytes. |
1996-09-18 |
2023-08-12 |
Not clear |
| H Sakuta, K Inaba, S Muramats. Calcitonin gene-related peptide enhances apoptosis of thymocytes. Journal of neuroimmunology. vol 67. issue 2. 1996-09-18. PMID:8765332. |
the effect of calcitonin gene-related peptide (cgrp), a neuropeptide, on the apoptosis of murine thymocytes was investigated. |
1996-09-18 |
2023-08-12 |
Not clear |