| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Song-Hao-Ran Sheng, Yu-Bin Li, Jia-Cheng Guo, Xiao-Lan Meng, Chen Wang, Miao He, Yu-Qiang Li, Hong-Zhi Su. [Huaier triggering mitochondria apoptosis in colorectal cancer cells through oxidative stress]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 12. 2024-07-23. PMID:39041095. |
western blot(wb) experiment was performed to determine apoptosis proteins and pink1/parkin pathway. |
2024-07-23 |
2024-07-25 |
Not clear |
| Lu Wang, Ran Luo, Yin-Xu Zhao, Yu Zou, Ming Bu, Yu Li. [Ergosterol peroxide inducing apoptosis of human hepatocellular carcinoma by regulating mitochondrial apoptosis pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 12. 2024-07-23. PMID:39041100. |
the effects of different concentrations of ep on the protein expression of mitochondrial apoptosis pathway-related proteins b cell lymphoma 2(bcl-2), cytochrome c(cyt-c), bcl-2-related x protein(bax), caspase-3, cleaved caspase-3, caspase-9, and cleaved caspase-9 were examined by using western blot. |
2024-07-23 |
2024-07-25 |
human |
| Yuan-Fang Fan, Xiao-Hui Su, Ying Xu, Xiang-Ying Kong, Li-Ling Liu, Ya-Ge Tian, Na Li. [Effect of triptolide on reproductive toxicity in female rats with Ⅱ type collagen induced arthritis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 11. 2024-07-23. PMID:39041166. |
in vitro, the mouse chinese hamster ovary(cho) cell line was established, and after 24 hours of tp administration(30, 60, 120 nmol·l~(-1)), cell proliferation was detected by the thiazolyl blue tetrazolium bromide(mtt) method, apoptosis by the flow cytometry, and tgfβ3, smad3 and sf-1 protein expression in cells by the western blot method, and the nuclear entry of sf-1 was detected by immunofluorescence. |
2024-07-23 |
2024-07-25 |
mouse |
| Shicun Zhang, Wei Zou, Yan Leng, Zhuang Mu, Lan Zha. Neuroprotective Effects of Metformin on Cerebral Ischemia-Reperfusion Injury: Modulation of JNK and p38 MAP Kinase Signaling Pathways. Cell biochemistry and biophysics. 2024-07-23. PMID:39043960. |
cell viability was measured with cell counting kit-8 (cck-8), protein expression via western blot (wb), and apoptosis through flow cytometry. |
2024-07-23 |
2024-07-26 |
mouse |
| Xuyuan Zhang, Ruize Zhang, Yinhai Wang, Liang Li, Zong Zhon. CDK5 Upregulated by ELF3 Transcription Promotes IL-1β-induced Inflammation and Extracellular Matrix Degradation in Human Chondrocytes. Cell biochemistry and biophysics. 2024-07-17. PMID:39020088. |
the levels of inflammatory cytokines were estimated using enzyme-linked immunosorbent assay (elisa) while the expressions of proteins implicated in extracellular matrix (ecm) degradation- and apoptosis were detected using western blot. |
2024-07-17 |
2024-07-20 |
human |
| Fang-Fang Zhong, Bo Wei, Guo-Xiang Bao, Yi-Ping Lou, Ming-Er Wei, Xin-Yue Wang, Xiao Xiao, Jin-Jin Tia. FABP3 Induces Mitochondrial Autophagy to Promote Neuronal Cell Apoptosis in Brain Ischemia-Reperfusion Injury. Neurotoxicity research. vol 42. issue 4. 2024-07-15. PMID:39008165. |
brain tissue injury, infarct volume ratio in the ischemic penumbra, neurologic deficits, behavioral abilities, neuronal apoptosis, apoptotic factors, inflammatory factors, and lipid peroxidation markers were assessed using h&e staining, ttc staining, longa scoring, rotation experiments, immunofluorescence staining, and western blot. |
2024-07-15 |
2024-07-18 |
mouse |
| Fang-Fang Zhong, Bo Wei, Guo-Xiang Bao, Yi-Ping Lou, Ming-Er Wei, Xin-Yue Wang, Xiao Xiao, Jin-Jin Tia. FABP3 Induces Mitochondrial Autophagy to Promote Neuronal Cell Apoptosis in Brain Ischemia-Reperfusion Injury. Neurotoxicity research. vol 42. issue 4. 2024-07-15. PMID:39008165. |
cell viability, apoptosis rate, mitochondrial oxidative stress, morphology, autophagosome formation, membrane potential, lc3 protein levels, and colocalization of autophagosomes and mitochondria were evaluated using mtt assay, ldh release assay, flow cytometry, ros/mda/gsh-px measurement, transmission electron microscopy, mitotracker staining, jc-1 method, western blot, and immunofluorescence staining. |
2024-07-15 |
2024-07-18 |
mouse |
| Xinke Chen, Lijuan Ouyang, Ning Ke, Lianhong Pi, Xiyuan Zho. Study on the role of MYCN in retinoblastoma by inhibiting p53 and activating wnt/βcatenin/Fra-1 signaling pathway by reducing DKK3. Drug development research. vol 85. issue 5. 2024-07-14. PMID:39003564. |
cell proliferation was evaluated using the cell counting kit-8 assay and 5-ethynyl-2'-deoxyuridine staining, while cell cycle progression and apoptosis were analyzed by flow cytometry and western blot analysis, respectively. |
2024-07-14 |
2024-07-16 |
Not clear |
| Salar Mahmoudi-Nejad, Sina Ahmadi, Mahssa Hassan-Nejhad, Mahdieh Azimi, Hanieh Dadvand, Morteza Bagher. Zinc Supplementation Reduces ROS Production and Prevents MDMA-Induced Apoptosis in TM3 Leydig Cells via the Inhibition of Pro-Apoptotic Proteins. Biological trace element research. 2024-07-14. PMID:39004669. |
the effect of different treatment groups in causing oxidative stress and apoptosis in tm3 cells was measured by dcf, tunnel, and western blot tests, respectively. |
2024-07-14 |
2024-07-18 |
Not clear |
| Fei Zhao, Dan-Yang Chen, Bo Jing, Yu Jiang, Lan-Yue Liu, Hui Son. Effect of Flammulina velutipes polysaccharide on mitochondrial apoptosis in lung adenocarcinoma A549 cells. Scientific reports. vol 14. issue 1. 2024-07-12. PMID:38997305. |
the results of flow cytometry experiments and mitochondrial membrane potential, rt-qpcr, and western blot showed that fvp-s1 and fvp-c were able to decrease the mitochondrial membrane potential, increase the expression level of apoptotic proteins casepase-3 and casepase-9 proteins, and at the same time, increase the ratio of bax and bcl-2, which promoted apoptosis of tumor cells. |
2024-07-12 |
2024-07-15 |
Not clear |
| Kaiqiang Zhong, Yingui Huang, Rui Chen, Qiusha Pan, Jun Li, Xiaotu X. The protective effect of ginsenoside Rg1 against sepsis-induced lung injury through PI3K-Akt pathway: insights from molecular dynamics simulation and experimental validation. Scientific reports. vol 14. issue 1. 2024-07-11. PMID:38992150. |
western blot results indicated that grg1 increased the bcl-2/bax protein expression ratio to reduce apoptosis and decreased the high expression of cleaved caspase-3 in lps-induced mle-12 cells. |
2024-07-11 |
2024-07-14 |
mouse |
| Qais Ibrahee. The Role of Matrix Metalloproteinase-2 (MMP2) in Colorectal Cancer Progression: Correlation With Clinicopathological Features and Impact on Cellular Processes. Cureus. vol 16. issue 6. 2024-07-10. PMID:38978899. |
the human crc cell line sw480 was treated with an mmp2 inhibitor, arp100, and evaluated for changes in cell migration, invasion, proliferation, and apoptosis using various assays, including mtt, wound-healing, transwell, caspase activity, and western blot analysis. |
2024-07-10 |
2024-07-12 |
human |
| Pengzhen Lei, Xiaoqing Wang, Xiaodong Qu, Rui Qi, Duanmingyu Chen, Yanhai Chan. The expression of SOCS1 is regulated by promoter DNA methylation and is associated with mitochondria-mediated apoptosis of T-2 induced chondrocytes. Experimental cell research. 2024-07-06. PMID:38971518. |
the expression of apoptosis related proteins (caspase-3 and caspase-9) and cytochrome c were detected using western blot. |
2024-07-06 |
2024-07-12 |
Not clear |
| Yongzhen Duan, Peixian Huang, Lu Sun, Panxia Wang, Yi Cai, Tingting Shi, Yuliang Li, Yuhua Zhou, Shanshan Y. Dehydroandrographolide ameliorates doxorubicin-mediated cardiotoxicity by regulating autophagy through the mTOR-TFEB pathway. Chemico-biological interactions. 2024-07-04. PMID:38964637. |
western blot and flow cytometry were used to measure apoptosis of cardiomyocytes. |
2024-07-04 |
2024-07-11 |
Not clear |
| Huixia Chen, Yulin Wu, Jiazheng Wang, Yike Li, Yongxue Chen, Xinbo Wang, Hangyu Lv, Xinyan Li. Tilianin enhances the antitumor effect of sufentanil on non-small cell lung cancer. Journal of biochemical and molecular toxicology. vol 38. issue 7. 2024-07-02. PMID:38952040. |
the functions of tilianin and sufentanil on nsclc cell viability, apoptosis, mitochondrial dysfunction, and immunity in vitro were examined using cell counting kit-8 assay, flow cytometry, reactive oxygen species level analysis, cd8+ t cell percentage analysis, western blot, and enzyme-linked immunosorbent assay, respectively. |
2024-07-02 |
2024-07-04 |
mouse |
| Huixia Chen, Yulin Wu, Jiazheng Wang, Yike Li, Yongxue Chen, Xinbo Wang, Hangyu Lv, Xinyan Li. Tilianin enhances the antitumor effect of sufentanil on non-small cell lung cancer. Journal of biochemical and molecular toxicology. vol 38. issue 7. 2024-07-02. PMID:38952040. |
meanwhile, the roles of tilianin and sufentanil in nsclc tumor growth, apoptosis, and immunity in vivo were determined by establishing a tumor xenograft mouse model, immunohistochemistry, and western blot assays. |
2024-07-02 |
2024-07-04 |
mouse |
| Ru Chen, Yanfei Zhang, Junhua Wang, Minghua Tao, Jiantao Ran, Jie Yang, Zi Wang, Li Pan, Qi Ha. [Knock-down of long noncoding RNA H19 (lncRNA H19) promotes human colorectal cell autophagy and inhibits cell apoptosis induced by lipopolysaccharide]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 40. issue 6. 2024-07-02. PMID:38952094. |
cell apoptosis was detected by flow cytometry, and the protein expression levels of apoptosis and autophagy markers were analyzed through western blot. |
2024-07-02 |
2024-07-04 |
human |
| Zhaoheng Wang, Daxue Zhu, Fengguang Yang, Haiwei Chen, Jihe Kang, Wenzhao Liu, Aixin Lin, Xuewen Kan. POSTN knockdown suppresses IL-1β-induced inflammation and apoptosis of nucleus pulposus cells via inhibiting the NF-κB pathway and alleviates intervertebral disc degeneration. Journal of cell communication and signaling. vol 18. issue 2. 2024-07-01. PMID:38946726. |
western blot, immunofluorescence, and tunel staining were used to detect the expression changes of inflammation, apoptosis and nf-κb pathway-related proteins in npcs. |
2024-07-01 |
2024-07-03 |
human |
| Ayşegül Çebi, Yalçın Tepe, İmren Alioglu, Ferda Ar. Inducing Effect of Corylus avellana on Cytotoxic Activity in Lung and Breast Cancer Cells via Apoptosis. Plant foods for human nutrition (Dordrecht, Netherlands). 2024-07-01. PMID:38949744. |
apoptosis was determined by performing caspase-mediated cytokeratin 18 (m30 elisa) and western blot analysis. |
2024-07-01 |
2024-07-03 |
Not clear |
| Kai Fu, Chuchu Gao, Xue Li, Hong Zhang, Boxin Xu. 3-chloro-1,2-propanediol induces oxidative stress and promotes testicular damage and infertility in rats through CYP2C9. Reproductive toxicology (Elmsford, N.Y.). 2024-06-29. PMID:38944211. |
cell viability, blood-testis barrier (btb) related protein, progesterone content, reactive oxygen species (ros) generation, and cell apoptosis were determined by a cck8 assay, western blot, elisa, flow cytometry, and tunel staining, respectively. |
2024-06-29 |
2024-07-02 |
mouse |