| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bader Huwaimel, Kareem M Younes, Amr S Abouzied, Akram M Elkashlan, Fawaz N Alheibshy, Ahmed Alobaida, Abdullah Turki, Saleh A Alquwaiay, Naif Alqahatani, Sulaiman A Alsuwayag. Phytochemical composition, in vitro cytotoxicity, and in silico docking properties of Tamarix tetragyna L. Scientific reports. vol 14. issue 1. 2024-10-27. PMID:39462121. |
in addition, in vitro cytoxicity activity versus cancer cell lines such mcf-7, hepg-2, hct-116, and a-549 was examined by mtt assay method, together with exploring its apoptosis effect by flow cytometry and western blot analysis techniques. |
2024-10-27 |
2024-10-29 |
Not clear |
| Xiaojing Hua, Qing Lu, Li Zen. SESN2 Ameliorates Dihydrotestosterone-induced Human Ovarian Granulosa Cell Damage by Activating AMPK/ULK1-mediated Mitophagy. Cell biochemistry and biophysics. 2024-10-17. PMID:39417977. |
the expression of sesn2, cell apoptosis, oxidative stress, mitophagy and ampk/ulk1 signaling-related proteins were measured by western blot. |
2024-10-17 |
2024-10-19 |
human |
| Wei-Yu Lin, Yu-Hsuan Cheng, Pei-Yu Liu, Shih-Ping Hsu, San-Chi Lin, Chiang-Ting Chie. Carvedilol through ß1-Adrenoceptor blockade ameliorates glomerulonephritis via inhibition of oxidative stress, apoptosis, autophagy, ferroptosis, endoplasmic reticulum stress and inflammation. Biochemical pharmacology. 2024-10-14. PMID:39401703. |
we examined rana and rena response to anti-thy1.1 and compared the effect of dnx or dnax on urinary oxidative stress, renal gp91, tyrosine hydroxylase (th), calcitonin gene-related peptide (cgrp), apoptosis, autophagy, ferroptosis, antioxidant enzymes, endoplasmic reticulum (er) stress and inflammation by western blot. |
2024-10-14 |
2024-10-17 |
rat |
| Mona Khoshbakht, Mohammad Mahdi Forghanifard, Hossein Aghamollaei, Jafar Aman. In silico and in vitro evaluation of a PE38 and Nb-based recombinant immunotoxin targeting the GRP78 receptor in cancer cells. Biotechnology and applied biochemistry. 2024-10-13. PMID:39397264. |
accordingly, the cytotoxicity, binding affinity, cell internalization, and apoptosis were evaluated using mtt, enzyme-linked immunosorbent assay, and western blot. |
2024-10-13 |
2024-10-16 |
Not clear |
| Sepideh Goudarzi, Razieh Mohammad Jafari, Nikou Farsiu, Behnam Amini, Mohammad Amin Manavi, Javad Fahanik-Babaei, Shahram Ejtemaei-Mehr, Ahmad Reza Dehpou. Protective Effects of Licofelone on Scopolamine-Induced Spatial Learning and Memory Impairment by Enhancing Parkin-Dependent Mitophagy and Promotion of Neural Regeneration and in Adult Mice. European journal of pharmacology. 2024-10-12. PMID:39395583. |
hippocampi were used to evaluate the levels of apoptosis via tunel assay, neural regeneration via immunohistochemistry method detecting doublecortin and nestin, and mitophagy via western blot of mitophagy proteins parkin and atg5. |
2024-10-12 |
2024-10-15 |
mouse |
| Bharathkumar Nagaraj, Arvind Sivasubramanian, Shazia Anjum Musthafa, Sadiq Muhammad, Aswathy Karanath Anilkumar, Ganesh Munuswamy-Ramanujam, Chinnaperumal Kamaraj, Sivaraman Dhanasekaran, Vetriselvan Subramaniya. Clerodane diterpene 3-deoxycaryoptinol (Clerodin) selectively induces apoptosis in human monocytic leukemia (THP-1) cells and upregulates apoptotic protein caspase-3. Free radical biology & medicine. 2024-10-11. PMID:39393554. |
moreover, the western blot was used to detect mitochondrial apoptosis of thp-1 cells. |
2024-10-11 |
2024-10-14 |
human |
| Beibei Qin, Dongfang Tang, Mingzhi Zhan. miR-149-3p targeting Biomolecules & biomedicine. 2024-10-10. PMID:39388706. |
western blot analysis was used to examine proteins related to migration, invasion, apoptosis, and tmprss4 expression. |
2024-10-10 |
2024-10-13 |
mouse |
| Jing Bai, Wen-Bo Sun, Wei-Chao Zheng, Xu-Peng Wang, Yang Ba. Carbon monoxide-releasing molecule-3 ameliorates traumatic brain injury-induced cardiac dysfunctions via inhibition of pyroptosis and apoptosis. Molecular and cellular biochemistry. 2024-10-08. PMID:39377871. |
24 h post-trauma, the cardiac function, pathological change, serum troponin t and creatine kinase-mb (ck-mb) levels, pyroptosis, apoptosis and expressions of tunel staining, gasdermin d (gsdmd), il-1β, il-18, ratio bax/bcl-2 were assessed by echocardiography, hematoxylin-eosin staining, chemiluminescence, immunofluorescence, and western blot assays, respectively. |
2024-10-08 |
2024-10-10 |
rat |
| Chuanlan Liu, Xiaomu Zhu, Erbu Aga, Wai Ming Tse, Kathy Wai Gaun Tse, Yanyong Liu, Bengui Y. Ebeiedinone and peimisine inhibit cigarette smoke extract-induced oxidative stress injury and apoptosis in BEAS-2B cells. Cell stress & chaperones. 2024-10-06. PMID:39370036. |
the western blot assay results indicate that ebeiedinone and peimisine reduce cse-induced oxidative stress, dna damage, apoptosis, and autophagy dysregulation by inhibiting ros, upregulating sod and gsh/gssg, and downregulating mda, 4-hne, and 8-ohdg through the nrf2/keap1 and jnk/mapk-dependent pathways, thereby delaying the pathological progression of copd caused by cs. |
2024-10-06 |
2024-10-09 |
human |
| Qiong Duan, Ruochen Li, Mingxiao Wang, Zhenting Cui, Xia Zhu, Fanghong Chen, Feng Han, Jianxin M. Exploring the anti-NSCLC mechanism of phillyrin targeting inhibition of the HSP90-AKT pathway. Naunyn-Schmiedeberg's archives of pharmacology. 2024-10-02. PMID:39356318. |
cck-8 assay, wound healing assay, apoptosis assay, western blot, and in vivo experiments verified the inhibitory effect of phn on nsclc. |
2024-10-02 |
2024-10-04 |
Not clear |
| Qian Yang, Qi-Ming Zhong, Mei-Qing Song, Li-Guo Tong, Chong-Zhi Ba. Exosomes derived from Danshen decoction-pretreated bone marrow mesenchymal stem cells alleviate myocardial infarction via anti-apoptosis and up-regulation of autophagy. Heliyon. vol 10. issue 18. 2024-09-30. PMID:39347388. |
on the 7th, 14th and 28th days, serum ck, ldh, α-hbdh, alt, and ast were measured and electrocardiogram changes were monitored to identify cardiac function; triphenyltetrazolium chloride staining, hematein&eosin staining, masson trichrome staining and transmission electron microscope were adopted to analyze infarct area, cardiac morphology, histopathology, and fibrosis and cardiomyocyte ultrastructure; tunel assay, real-time pcr and western blot were performed to detect cardiomyocyte apoptosis and autophagy. |
2024-09-30 |
2024-10-02 |
rat |
| Li Qiu, Zhaoming Huan. Downregulation of IGFBP7 Alleviates LPS-induced Inflammation and Apoptosis in WI-38 Cells via Enhancing Mitophagy. Cell biochemistry and biophysics. 2024-09-30. PMID:39347911. |
next, igfbp7 interference plasmid was constructed, and cell viability and apoptosis were detected by cck8, flow cytometry and western blot. |
2024-09-30 |
2024-10-02 |
human |
| Yafei Zhu, Xinlin Zhao, Tibenda Jonnea Japhet, Jun Chen, Qipeng Zha. Sampling of N-methyl-N-nitrosourea-induced Rat's Retina Damage and Multi-index Evaluation of Pathological Changes. Journal of visualized experiments : JoVE. issue 211. 2024-09-30. PMID:39345110. |
additionally, we performed hematoxylin-eosin staining to assess retinal pathological changes. determination of the apoptosis rate and apoptosis protein by tunel and western blot. |
2024-09-30 |
2024-10-02 |
rat |
| Selman Gencer, Cihan Gür, Mustafa İleritürk, Sefa Küçükler, Nurhan Akaras, Hasan Şimşek, Fatih M Kandemi. The ameliorative effect of carvacrol on sodium arsenite-induced hepatotoxicity in rats: Possible role of Nrf2/HO-1, RAGE/NLRP3, Bax/Bcl-2/Caspase-3, and Beclin-1 pathways. Journal of biochemical and molecular toxicology. vol 38. issue 10. 2024-09-25. PMID:39318027. |
oxidative stress, inflammation, apoptosis, autophagy damage pathways parameters, and liver tissue integrity were analyzed using biochemical, molecular, western blot, histological, and immunohistological methods. |
2024-09-25 |
2024-09-27 |
rat |
| Nan Jiang, Jiawei Kang, Yi Ding, Munire Shataer, Liangying Ma, Tayier Tuerson. MiR-509-3p promotes gastric cancer development by activating FOXM1-mediated p38/MK2 pathway. Biomolecules & biomedicine. 2024-09-25. PMID:39319839. |
cck-8, edu, transwell, wound healing assays, flow cytometry, and western blot analysis were employed to examine changes in proliferation, migration, invasion, apoptosis, foxm1, and the p38 mapk (p38)/mapk-activated protein kinase 2 (mk2) pathway in gc cells (mnk-45 and hgc-27) after mir-509-3p overexpression or knockdown, foxm1 overexpression, and application of the p38 pathway agonist anisomycin. |
2024-09-25 |
2024-09-27 |
Not clear |
| Yaping Xu, Chundong Yu, Hongbin Zhang, Tao Wang, Yujian Liu, Lupeng Wu, Shuping Zhong, Zaifa Hon. Downregulation of Brf1 Induces Liver Failure and Inhibits Hepatocellular Carcinoma Progression by Promoting Apoptosis. Journal of Cancer. vol 15. issue 17. 2024-09-24. PMID:39308682. |
western blot (wb) analysis, flow cytometry, and tunel assays were used to detect apoptosis. |
2024-09-24 |
2024-09-26 |
mouse |
| Xiangjun Yi, Xuan Chen, Zhenbin L. miR-200c targeting GLI3 inhibits cell proliferation and promotes apoptosis in non-small cell lung cancer cells. Medicine. vol 103. issue 38. 2024-09-23. PMID:39312343. |
the cell viability rate was detected by cell counting kit-8, cell invasion ability was detected with transwell, cell apoptosis and cell cycle was determined by flow cytometry, and the expression of gli3 was detected using quantitative polymerase chain reaction and western blot, to verify the effect of the interaction between mir-200c-3p and gli3 on the cell activities. |
2024-09-23 |
2024-09-26 |
Not clear |
| Marta Henklewska, Aleksandra Pawlak, Bożena Obmińska-Mrukowic. Targeting ATR Kinase as a Strategy for Canine Lymphoma and Leukaemia Treatment. Veterinary and comparative oncology. 2024-09-20. PMID:39300906. |
further, we estimated the level of apoptosis in berzosertib-treated cells via flow cytometry and assessed h2ax phosphorylation as a marker of dna damage using western blot technique. |
2024-09-20 |
2024-09-22 |
human |
| Feng Hu, Senbo Yan, Li Lin, Xiaoxia Qiu, Xinghe Lin, Weiwei Wan. Sacubitril/valsartan attenuated myocardial inflammation, fibrosis, apoptosis and promoted autophagy in doxorubicin-induced cardiotoxicity mice via regulating the AMPKα-mTORC1 signaling pathway. Molecular and cellular biochemistry. 2024-09-20. PMID:39304614. |
a variety of techniques were used to investigate cardiac inflammation, fibrosis, apoptosis, and autophagy, including western blot, real-time quantitative pcr (rt-qpcr), immunohistochemistry, and fluorescence. |
2024-09-20 |
2024-09-23 |
mouse |
| Menglan Liu, Zuoxiao Li, Zhiyu Lv, Yang Xi. Discussion of spinal cord neurons apoptosis and neuroprotection mechanism of NGF gene transfection mediated by recombinant adenovirus in EAE mice. Scientific reports. vol 14. issue 1. 2024-09-17. PMID:39289437. |
aqthe tunel method was employed to observe spinal neuron apoptosis in each group of mice; protein immunoblotting (western blot) and rt-pcr were used to measure ngf levels in the spinal cord tissues of each group, and western blotting was used to assess levels of cleaved caspase-3, bax, and bcl-2. |
2024-09-17 |
2024-09-20 |
mouse |