| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Cabral, J De Ross, V M Castilho, M L Brandão, M J Nobr. Glutamate receptor antagonism in inferior colliculus attenuates elevated startle response of high anxiety diazepam-withdrawn rats. Neuroscience. vol 161. issue 3. 2009-08-24. PMID:19348870. |
in addition, since bzp withdrawal may function as an unconditioned stressor, the negative affective states observed in ha rats could be a by-product of gaba-glutamate imbalance in brain systems that modulate unconditioned fear and anxiety behaviors, since the blockade of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (ampa) and n-methyl-d-aspartate (nmda) glutamate receptors in the cic clearly reduced the aversion promoted by diazepam withdrawal. |
2009-08-24 |
2023-08-12 |
rat |
| Tzu-Lan Liu, Der-Yow Chen, K C Lian. Post-training infusion of glutamate into the bed nucleus of the stria terminalis enhanced inhibitory avoidance memory: an effect involving norepinephrine. Neurobiology of learning and memory. vol 91. issue 4. 2009-05-26. PMID:19186212. |
this study examined an interaction between glutamate and norepinephrine in the bed nucleus of the stria terminalis (bnst) in modulating affective memory formation. |
2009-05-26 |
2023-08-12 |
rat |
| Houman Homayoun, Bita Moghadda. Orbitofrontal cortex neurons as a common target for classic and glutamatergic antipsychotic drugs. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 46. 2008-12-17. PMID:19004793. |
new evidence that agonists of the metabotropic glutamate 2/3 (mglu2/3) receptors ameliorate psychotic and affective symptoms of schizophrenia suggests that compounds with different molecular targets may act on a common cellular target to treat schizophrenia. |
2008-12-17 |
2023-08-12 |
rat |
| V M Pickel, E E Colago, I Mania, A I Molosh, D G Rainni. Dopamine D1 receptors co-distribute with N-methyl-D-aspartic acid type-1 subunits and modulate synaptically-evoked N-methyl-D-aspartic acid currents in rat basolateral amygdala. Neuroscience. vol 142. issue 3. 2007-01-03. PMID:16905271. |
activation of dopamine d1 or glutamate, n-methyl-d-aspartic acid (nmda) receptors in the basolateral amygdala (bla) can potently influence affective behaviors and associative learning. |
2007-01-03 |
2023-08-12 |
rat |
| S J Mathew, J D Coplan, D D Schoepp, E L Smith, L A Rosenblum, J M Gorma. Glutamate-hypothalamic-pituitary-adrenal axis interactions: implications for mood and anxiety disorders. CNS spectrums. vol 6. issue 7. 2005-05-03. PMID:15573019. |
ultimately, hpa axis modulators, serotonin-enhancing agents, and glutamate antagonists might serve to increase neurotropic factors in key brain regions for affective and anxiety regulation, providing a putative final common pathway. |
2005-05-03 |
2023-08-12 |
Not clear |
| Yumiko Sekiya, Takayuki Nakagawa, Tohru Ozawa, Masabumi Minami, Masamichi Sato. Facilitation of morphine withdrawal symptoms and morphine-induced conditioned place preference by a glutamate transporter inhibitor DL-threo-beta-benzyloxyaspartate in rats. European journal of pharmacology. vol 485. issue 1-3. 2004-10-05. PMID:14757142. |
these results suggest that central glutamate transporters play inhibitory roles in the expression of somatic and negative affective components of morphine withdrawal and the reinforcing effect of morphine. |
2004-10-05 |
2023-08-12 |
rat |
| Yumiko Sekiya, Takayuki Nakagawa, Tohru Ozawa, Masabumi Minami, Masamichi Sato. Facilitation of morphine withdrawal symptoms and morphine-induced conditioned place preference by a glutamate transporter inhibitor DL-threo-beta-benzyloxyaspartate in rats. European journal of pharmacology. vol 485. issue 1-3. 2004-10-05. PMID:14757142. |
administration of a potent glutamate transporter inhibitor, dl-threo-beta-benzyloxyaspartate (dl-tboa), on acute morphine-induced antinociception, expression of somatic and negative affective components of morphine withdrawal, and acquisition of morphine-induced conditioned place preference in rats. |
2004-10-05 |
2023-08-12 |
rat |
| Susan R Sesack, David B Carr, Natalia Omelchenko, Aline Pint. Anatomical substrates for glutamate-dopamine interactions: evidence for specificity of connections and extrasynaptic actions. Annals of the New York Academy of Sciences. vol 1003. 2004-02-13. PMID:14684434. |
for normal regulation of motor, affective, and cognitive functions, dopamine provides an essential modulation of glutamate transmission within multiple brain regions. |
2004-02-13 |
2023-08-12 |
Not clear |
| Takeshi Watanabe, Takayuki Nakagawa, Rie Yamamoto, Akifumi Maeda, Masabumi Minami, Masamichi Sato. Involvement of glutamate receptors within the central nucleus of the amygdala in naloxone-precipitated morphine withdrawal-induced conditioned place aversion in rats. Japanese journal of pharmacology. vol 88. issue 4. 2002-12-12. PMID:12046982. |
in the present study, we investigated the role of glutamate receptors within the cea in the negative affective component of morphine abstinence by evaluating naloxone-precipitated withdrawal-induced conditioned place aversion (cpa) in morphine-dependent rats. |
2002-12-12 |
2023-08-12 |
rat |
| D E Dietrich, M Schedlowski, L Bode, H Ludwig, H M Emric. A viro-psycho-immunological disease-model of a subtype affective disorder. Pharmacopsychiatry. vol 31. issue 3. 1998-09-17. PMID:9657234. |
in addition, a specific affinity of bdv structural elements for aspartate and glutamate receptors in the hippocampal formation might directly induce an imbalance of these transmitter system interactions, causing affective and behavioral disturbances. |
1998-09-17 |
2023-08-12 |
human |