| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| James M Robertson, Justin K Achua, Justin P Smith, Melissa A Prince, Clarissa D Staton, Patrick J Ronan, Tangi R Summers, Cliff H Summer. Anxious behavior induces elevated hippocampal Cb Neuroscience. vol 352. 2018-03-05. PMID:28392296. |
the hippocampus plays important roles in the regulation of affective behavior, emotion, and anxiety, as well as memory. |
2018-03-05 |
2023-08-13 |
Not clear |
| Karen R Mifsud, Johannes M H M Reu. Acute stress enhances heterodimerization and binding of corticosteroid receptors at glucocorticoid target genes in the hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 40. 2018-02-07. PMID:27655894. |
a stressful event results in secretion of glucocorticoid hormones, which bind to mineralocorticoid receptors (mrs) and glucocorticoid receptors (grs) in the hippocampus to regulate cognitive and affective responses to the challenge. |
2018-02-07 |
2023-08-13 |
Not clear |
| Eunchai Kang, Zhexing Wen, Hongjun Song, Kimberly M Christian, Guo-Li Min. Adult Neurogenesis and Psychiatric Disorders. Cold Spring Harbor perspectives in biology. vol 8. issue 9. 2017-11-24. PMID:26801682. |
constitutive neurogenesis in the hippocampus of the mature brain reflects large-scale plasticity unique to this region and could be a potential hub for modulation of a subset of cognitive and affective behaviors that are affected by multiple psychiatric disorders. |
2017-11-24 |
2023-08-13 |
Not clear |
| Judith Baka, Eszter Csakvari, Orsolya Huzian, Nikoletta Dobos, Laszlo Siklos, Csaba Leranth, Neil J MacLusky, Ronald S Duman, Tibor Hajsza. Stress induces equivalent remodeling of hippocampal spine synapses in a simulated postpartum environment and in a female rat model of major depression. Neuroscience. vol 343. 2017-11-17. PMID:28012870. |
in line with our emerging 'synaptogenic hypothesis' of depression, the loss of hippocampal spine synapses may be a novel perspective both in the pathomechanism and in the clinical management of postpartum affective illness. |
2017-11-17 |
2023-08-13 |
rat |
| S Yu, I Zutshi, R Stoffel, J Zhang, A P Ventura-Silva, N Sousa, P S Costa, F Holsboer, A Patchev, O F X Almeid. Antidepressant responsiveness in adulthood is permanently impaired after neonatal destruction of the neurogenic pool. Translational psychiatry. vol 7. issue 1. 2017-11-16. PMID:28045461. |
the dynamic turnover of hippocampal neurons is implicated in the regulation of cognitive and affective behavior. |
2017-11-16 |
2023-08-13 |
rat |
| Charlotte Hentze, Henrik Walter, Elisabeth Schramm, Sarah Drost, Dieter Schoepf, Thomas Fangmeier, Margarete Mattern, Claus Normann, Ingo Zobel, Knut Schnel. Functional Correlates of childhood maltreatment and symptom severity during affective theory of mind tasks in chronic depression. Psychiatry research. Neuroimaging. vol 250. 2017-11-08. PMID:27107154. |
amygdala activation during affective tom correlated positively with ctq total scores, while (para)hippocampal response correlated negatively with madrs scores. |
2017-11-08 |
2023-08-13 |
Not clear |
| Bhanu Chandra Karisetty, Swati Maitra, Abhipradnya Bipin Wahul, Anusha Musalamadugu, Nitin Khandelwal, Sumasri Guntupalli, Ramya Garikapati, Thatiparthi Jhansyrani, Arvind Kumar, Sumana Chakravart. Differential effect of chronic stress on mouse hippocampal memory and affective behavior: Role of major ovarian hormones. Behavioural brain research. vol 318. 2017-11-06. PMID:27780721. |
differential effect of chronic stress on mouse hippocampal memory and affective behavior: role of major ovarian hormones. |
2017-11-06 |
2023-08-13 |
mouse |
| Bhanu Chandra Karisetty, Swati Maitra, Abhipradnya Bipin Wahul, Anusha Musalamadugu, Nitin Khandelwal, Sumasri Guntupalli, Ramya Garikapati, Thatiparthi Jhansyrani, Arvind Kumar, Sumana Chakravart. Differential effect of chronic stress on mouse hippocampal memory and affective behavior: Role of major ovarian hormones. Behavioural brain research. vol 318. 2017-11-06. PMID:27780721. |
so, to understand the stress-induced mood and cognitive disorders in intact females (with ovaries) and ovariectomized (ovx) females, we studied changes in mouse hippocampus, a functionally heterogeneous neural structure involved in both affective and cognitive behaviors. |
2017-11-06 |
2023-08-13 |
mouse |
| Bhanu Chandra Karisetty, Swati Maitra, Abhipradnya Bipin Wahul, Anusha Musalamadugu, Nitin Khandelwal, Sumasri Guntupalli, Ramya Garikapati, Thatiparthi Jhansyrani, Arvind Kumar, Sumana Chakravart. Differential effect of chronic stress on mouse hippocampal memory and affective behavior: Role of major ovarian hormones. Behavioural brain research. vol 318. 2017-11-06. PMID:27780721. |
we report that the presence or absence of ovarian hormones, particularly the estrogen, has a significant impact in altering the hippocampus related spatial memory and affective behavior, in females. |
2017-11-06 |
2023-08-13 |
mouse |
| D Borsook, C Linnman, V Faria, A M Strassman, L Becerra, I Elma. Reward deficiency and anti-reward in pain chronification. Neuroscience and biobehavioral reviews. vol 68. 2017-10-23. PMID:27246519. |
anti-reward (ar) conversely pertains to a between-systems neuroadaptation involving over-recruitment of key limbic structures (e.g., the central and basolateral amygdala nuclei, the bed nucleus of the stria terminalis, the lateral tegmental noradrenergic nuclei of the brain stem, the hippocampus and the habenula) responsible for massive outpouring of stressogenic neurochemicals (e.g., norepinephrine, corticotropin releasing factor, vasopressin, hypocretin, and substance p) giving rise to such negative affective states as anxiety, fear and depression. |
2017-10-23 |
2023-08-13 |
Not clear |
| Luis E B Bettio, Luckshi Rajendran, Joana Gil-Mohape. The effects of aging in the hippocampus and cognitive decline. Neuroscience and biobehavioral reviews. vol 79. 2017-10-23. PMID:28476525. |
one structure of particular interest when considering aging and cognitive decline is the hippocampus, a brain region known to play an important role in learning and memory consolidation as well as in affective behaviours and mood regulation, and where both functional and structural plasticity (e.g., neurogenesis) occur well into adulthood. |
2017-10-23 |
2023-08-13 |
Not clear |
| Farhana Yasmin, Kapil Saxena, Bruce S McEwen, Sumantra Chattarj. The delayed strengthening of synaptic connectivity in the amygdala depends on NMDA receptor activation during acute stress. Physiological reports. vol 4. issue 20. 2017-10-17. PMID:27798355. |
there is growing evidence that stress leads to contrasting patterns of structural plasticity in the hippocampus and amygdala, two brain areas implicated in the cognitive and affective symptoms of stress-related psychiatric disorders. |
2017-10-17 |
2023-08-13 |
rat |
| Shaozheng Qin, Xujun Duan, Kaustubh Supekar, Huafu Chen, Tianwen Chen, Vinod Meno. Large-scale intrinsic functional network organization along the long axis of the human medial temporal lobe. Brain structure & function. vol 221. issue 6. 2017-09-28. PMID:26336951. |
the hippocampus showed stronger connectivity with striatum, ventral tegmental area and amygdala-regions important for integrating reward and affective signals, whereas the phg showed stronger connectivity with unimodal and polymodal association cortices. |
2017-09-28 |
2023-08-13 |
human |
| Roee Admon, Michael T Treadway, Linda Valeri, Malavika Mehta, Samuel Douglas, Diego A Pizzagall. Distinct Trajectories of Cortisol Response to Prolonged Acute Stress Are Linked to Affective Responses and Hippocampal Gray Matter Volume in Healthy Females. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 33. 2017-09-11. PMID:28739584. |
distinct trajectories of cortisol response to prolonged acute stress are linked to affective responses and hippocampal gray matter volume in healthy females. |
2017-09-11 |
2023-08-13 |
Not clear |
| Luis E B Bettio, Anna R Patten, Joana Gil-Mohapel, Natasha F O'Rourke, Ronan P Hanley, Samantha Kennedy, Karthik Gopalakrishnan, Ana Lúcia S Rodrigues, Jeremy Wulff, Brian R Christi. ISX-9 can potentiate cell proliferation and neuronal commitment in the rat dentate gyrus. Neuroscience. vol 332. 2017-09-05. PMID:27373772. |
given the proposed role of this form of structural plasticity in the functioning of the hippocampus (namely learning and memory and affective behaviors), it is believed that alterations in hippocampal neurogenesis might underlie some of the behavioral deficits associated with these psychiatric and neurological conditions. |
2017-09-05 |
2023-08-13 |
rat |
| Luis E B Bettio, Anna R Patten, Joana Gil-Mohapel, Natasha F O'Rourke, Ronan P Hanley, Samantha Kennedy, Karthik Gopalakrishnan, Ana Lúcia S Rodrigues, Jeremy Wulff, Brian R Christi. ISX-9 can potentiate cell proliferation and neuronal commitment in the rat dentate gyrus. Neuroscience. vol 332. 2017-09-05. PMID:27373772. |
future studies are thus warranted to evaluate the pro-neurogenic properties of isx-9 in animal models of affective and neurological disorders associated with impaired hippocampal structural plasticity. |
2017-09-05 |
2023-08-13 |
rat |
| Laura K Fonken, Matthew G Frank, Meagan M Kitt, Heather M D'Angelo, Diana M Norden, Michael D Weber, Ruth M Barrientos, Jonathan P Godbout, Linda R Watkins, Steven F Maie. The Alarmin HMGB1 Mediates Age-Induced Neuroinflammatory Priming. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 30. 2017-07-10. PMID:27466339. |
icm pretreatment of aged rats with box-a 24 h before e. coli infection prevented the extended hippocampal cytokine response and associated cognitive and affective behavioral changes. |
2017-07-10 |
2023-08-13 |
rat |
| Suyun Zhang, Juan Hong, Tingting Zhang, Jie Wu, Ling Che. Activation of Sigma-1 Receptor Alleviates Postpartum Estrogen Withdrawal-Induced "Depression" Through Restoring Hippocampal nNOS-NO-CREB Activities in Mice. Molecular neurobiology. vol 54. issue 4. 2017-07-07. PMID:27032391. |
affective behaviors as assessed by forced swim and tail suspension tests, hippocampal neuronal nitric oxide synthase (nnos), nitric oxide (no), cyclic amp (camp) response element binding protein (creb) phosphorylation (phosphor-creb), and neurosteroidogenesis were examined before e2 withdrawal (ew; hsp mice) and on days 2-4 (early-ew mice) and days 8-10 (late-ew mice) after ew. |
2017-07-07 |
2023-08-13 |
mouse |
| Ural Verimli, Umit S Sehirl. Glutamic acid decarboxylase isoform distribution in transgenic mouse septum: an anti-GFP immunofluorescence study. Anatomical science international. vol 91. issue 4. 2017-03-02. PMID:26643381. |
medial septal projections regulate hippocampal theta rhythm whereas lateral septal projections are involved in processes such as affective functions, memory formation, and behavioral responses. |
2017-03-02 |
2023-08-13 |
mouse |
| Robert J Buchanan, Klevest Gjini, Pradeep Modur, Kevin T Meier, Zoltan Nadasdy, Jennifer L Robinso. In vivo measurements of limbic glutamate and GABA concentrations in epileptic patients during affective and cognitive tasks: A microdialysis study. Hippocampus. vol 26. issue 5. 2017-01-06. PMID:26606278. |
limbic system structures such as the amygdala (amg) and the hippocampus (hipp) are involved in affective and cognitive processing. |
2017-01-06 |
2023-08-13 |
human |