| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K J Jackson, M I Dama. L-type calcium channels and calcium/calmodulin-dependent kinase II differentially mediate behaviors associated with nicotine withdrawal in mice. The Journal of pharmacology and experimental therapeutics. vol 330. issue 1. 2009-07-27. PMID:19336664. |
pharmacological data suggest that camkii is involved in somatic signs and affective nicotine withdrawal, and activity level is decreased after nicotine withdrawal, whereas the genetic assessments yielded results suggesting that camkii is involved only in the anxiety-related response, yet the kinase activity may be increased after nicotine withdrawal; thus, future studies are necessary to clarify the precise behavioral specifics of the relevance of camkii in nicotine withdrawal behaviors. |
2009-07-27 |
2023-08-12 |
mouse |
| K J Jackson, D H Kota, B R Martin, M I Dama. The role of various nicotinic receptor subunits and factors influencing nicotine conditioned place aversion. Neuropharmacology. vol 56. issue 6-7. 2009-07-07. PMID:19371584. |
affective nicotine withdrawal symptoms are of major motivational significance in contributing to relapse and continued tobacco use; thus, it is important to understand the molecular and receptor-mediated mechanisms that mediate affective withdrawal behaviors. |
2009-07-07 |
2023-08-12 |
mouse |
| Raffaella Isola, Hailin Zhang, Gopi A Tejwani, Norton H Neff, Maria Hadjiconstantino. Acute nicotine changes dynorphin and prodynorphin mRNA in the striatum. Psychopharmacology. vol 201. issue 4. 2009-04-01. PMID:18807250. |
the kappa-dynorphinergic system has been associated with negative motivational and affective states, and whether dynorphin (dyn) contributes to the behavioral pharmacology of nicotine is a pertinent question. |
2009-04-01 |
2023-08-12 |
Not clear |
| Freda Patterson, Christopher Jepson, Andrew A Strasser, James Loughead, Kenneth A Perkins, Ruben C Gur, Joseph M Frey, Steven Siegel, Caryn Lerma. Varenicline improves mood and cognition during smoking abstinence. Biological psychiatry. vol 65. issue 2. 2009-03-20. PMID:18842256. |
its effects on the affective and cognitive dimensions of nicotine withdrawal have yet to be well characterized. |
2009-03-20 |
2023-08-12 |
Not clear |
| Adrie W Bruijnzeel, Athina Marko. Decreased sensitivity to the effects of dopamine D1-like, but not D2-like, receptor antagonism in the posterior hypothalamic region/anterior ventral tegmental area on brain reward function during chronic exposure to nicotine in rats. Brain research. vol 1058. issue 1-2. 2009-01-26. PMID:16126181. |
decreased sensitivity to d1-like receptor antagonism in the posterior hypothalamus/anterior vta may partly mediate the development of tolerance to the reinforcing effects of nicotine and the manifestation of negative affective signs associated with cessation of nicotine administration. |
2009-01-26 |
2023-08-12 |
rat |
| Adam Rzetelny, David G Gilbert, Jonathan Hammersley, Robert Radtke, Norka E Rabinovich, Stacey L Smal. Nicotine decreases attentional bias to negative-affect-related Stroop words among smokers. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 10. issue 6. 2008-11-18. PMID:18584466. |
the present study examined the hypothesis that nicotine is associated with reduced attentional bias to affective and smoking-related stimuli in a modified stroop task. |
2008-11-18 |
2023-08-12 |
Not clear |
| Saul Shiffma. Effect of nicotine lozenges on affective smoking withdrawal symptoms: secondary analysis of a randomized, double-blind, placebo-controlled clinical trial. Clinical therapeutics. vol 30. issue 8. 2008-10-20. PMID:18803988. |
effect of nicotine lozenges on affective smoking withdrawal symptoms: secondary analysis of a randomized, double-blind, placebo-controlled clinical trial. |
2008-10-20 |
2023-08-12 |
Not clear |
| Astrid K Stoker, Svetlana Semenova, Athina Marko. Affective and somatic aspects of spontaneous and precipitated nicotine withdrawal in C57BL/6J and BALB/cByJ mice. Neuropharmacology. vol 54. issue 8. 2008-08-25. PMID:18452957. |
affective and somatic aspects of spontaneous and precipitated nicotine withdrawal in c57bl/6j and balb/cbyj mice. |
2008-08-25 |
2023-08-12 |
mouse |
| Astrid K Stoker, Svetlana Semenova, Athina Marko. Affective and somatic aspects of spontaneous and precipitated nicotine withdrawal in C57BL/6J and BALB/cByJ mice. Neuropharmacology. vol 54. issue 8. 2008-08-25. PMID:18452957. |
we evaluated measures of affective and somatic aspects of nicotine withdrawal in c57bl/6j and balb/cbyj mice. |
2008-08-25 |
2023-08-12 |
mouse |
| Astrid K Stoker, Svetlana Semenova, Athina Marko. Affective and somatic aspects of spontaneous and precipitated nicotine withdrawal in C57BL/6J and BALB/cByJ mice. Neuropharmacology. vol 54. issue 8. 2008-08-25. PMID:18452957. |
in conclusion, administration of relatively high nicotine doses over prolonged periods of time induces both the affective and somatic aspects of spontaneous nicotine withdrawal in the mouse, while exposure to nicotine for shorter periods of time is sufficient for nachr antagonist-precipitated nicotine withdrawal. |
2008-08-25 |
2023-08-12 |
mouse |
| Paul M Johnson, Jonathan A Hollander, Paul J Kenn. Decreased brain reward function during nicotine withdrawal in C57BL6 mice: evidence from intracranial self-stimulation (ICSS) studies. Pharmacology, biochemistry, and behavior. vol 90. issue 3. 2008-08-25. PMID:18466962. |
further, these findings highlight the potential utility of the icss procedure for assessing this important affective component of nicotine withdrawal in genetically modified mice. |
2008-08-25 |
2023-08-12 |
mouse |
| Marina R Picciotto, Nii A Addy, Yann S Mineur, Darlene H Brunzel. It is not "either/or": activation and desensitization of nicotinic acetylcholine receptors both contribute to behaviors related to nicotine addiction and mood. Progress in neurobiology. vol 84. issue 4. 2008-07-30. PMID:18242816. |
this review will examine the evidence for the contribution of these two very different consequences of nicotine administration to behaviors related to nicotine addiction, including processes related to drug reinforcement and affective modulation. |
2008-07-30 |
2023-08-12 |
Not clear |
| Marina R Picciotto, Nii A Addy, Yann S Mineur, Darlene H Brunzel. It is not "either/or": activation and desensitization of nicotinic acetylcholine receptors both contribute to behaviors related to nicotine addiction and mood. Progress in neurobiology. vol 84. issue 4. 2008-07-30. PMID:18242816. |
we conclude that there are effects of nachr activation and desensitization on drug reinforcement and affective behavior, and that both processes are important in the behavioral consequences of nicotine in tobacco smoking. |
2008-07-30 |
2023-08-12 |
Not clear |
| Jessica M André, Danielle Gulick, George S Portugal, Thomas J Goul. Nicotine withdrawal disrupts both foreground and background contextual fear conditioning but not pre-pulse inhibition of the acoustic startle response in C57BL/6 mice. Behavioural brain research. vol 190. issue 2. 2008-07-30. PMID:18367257. |
although animal models have provided insights into the somatic and affective symptoms of nicotine withdrawal, less research has focused on the effects of nicotine withdrawal on cognition. |
2008-07-30 |
2023-08-12 |
mouse |
| Patricia Vieyra-Reyes, Marina R Picciotto, Yann S Mineu. Voluntary oral nicotine intake in mice down-regulates GluR2 but does not modulate depression-like behaviors. Neuroscience letters. vol 434. issue 1. 2008-07-03. PMID:18261852. |
these results suggest that voluntary nicotine drinking induces nicotine preference in mice, but does not alter a number of affective behaviors. |
2008-07-03 |
2023-08-12 |
mouse |
| Raffaella Isola, Hailing Zhang, Gopi A Tejwani, Norton H Neff, Maria Hadjiconstantino. Dynorphin and prodynorphin mRNA changes in the striatum during nicotine withdrawal. Synapse (New York, N.Y.). vol 62. issue 6. 2008-07-02. PMID:18361441. |
nicotine withdrawal causes somatic and negative affective symptoms that contribute to relapse and continued tobacco smoking. |
2008-07-02 |
2023-08-12 |
mouse |
| Raffaella Isola, Hailing Zhang, Gopi A Tejwani, Norton H Neff, Maria Hadjiconstantino. Dynorphin and prodynorphin mRNA changes in the striatum during nicotine withdrawal. Synapse (New York, N.Y.). vol 62. issue 6. 2008-07-02. PMID:18361441. |
heightened dynorphinergic tone might be responsible, in part, for the emergence of the negative affective states observed during nicotine withdrawal. |
2008-07-02 |
2023-08-12 |
mouse |
| Bonnie Spring, Jessica Werth Cook, Bradley Appelhans, Anne Maloney, Malia Richmond, Jocelyn Vaughn, Joseph Vanderveen, Donald Hedeke. Nicotine effects on affective response in depression-prone smokers. Psychopharmacology. vol 196. issue 3. 2008-05-30. PMID:17960366. |
nicotine effects on affective response in depression-prone smokers. |
2008-05-30 |
2023-08-12 |
Not clear |
| Anthony S Rauhut, Isaac J Zentner, Stacey K Mardekian, Jason B Tanenbau. Wistar Kyoto and Wistar rats differ in the affective and locomotor effects of nicotine. Physiology & behavior. vol 93. issue 1-2. 2008-04-22. PMID:17889041. |
wistar kyoto and wistar rats differ in the affective and locomotor effects of nicotine. |
2008-04-22 |
2023-08-12 |
rat |
| K J Jackson, B R Martin, J P Changeux, M I Dama. Differential role of nicotinic acetylcholine receptor subunits in physical and affective nicotine withdrawal signs. The Journal of pharmacology and experimental therapeutics. vol 325. issue 1. 2008-04-22. PMID:18184829. |
differential role of nicotinic acetylcholine receptor subunits in physical and affective nicotine withdrawal signs. |
2008-04-22 |
2023-08-12 |
mouse |